PL117107B1 - Process for preparing novel 4a,9b-trans-5-aryl-2,3,4,4a,5,9b-hexahydro-1h-pyrido/4,3-b/indoles-geksagirdid 1h-pirido 4,3-b ionidolov - Google Patents

Process for preparing novel 4a,9b-trans-5-aryl-2,3,4,4a,5,9b-hexahydro-1h-pyrido/4,3-b/indoles-geksagirdid 1h-pirido 4,3-b ionidolov Download PDF

Info

Publication number
PL117107B1
PL117107B1 PL1978215921A PL21592178A PL117107B1 PL 117107 B1 PL117107 B1 PL 117107B1 PL 1978215921 A PL1978215921 A PL 1978215921A PL 21592178 A PL21592178 A PL 21592178A PL 117107 B1 PL117107 B1 PL 117107B1
Authority
PL
Poland
Prior art keywords
formula
trans
hexahydro
compounds
pyrido
Prior art date
Application number
PL1978215921A
Other languages
English (en)
Polish (pl)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of PL117107B1 publication Critical patent/PL117107B1/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurosurgery (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Psychiatry (AREA)
  • Anesthesiology (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PL1978215921A 1977-05-23 1978-05-18 Process for preparing novel 4a,9b-trans-5-aryl-2,3,4,4a,5,9b-hexahydro-1h-pyrido/4,3-b/indoles-geksagirdid 1h-pirido 4,3-b ionidolov PL117107B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US79939277A 1977-05-23 1977-05-23

Publications (1)

Publication Number Publication Date
PL117107B1 true PL117107B1 (en) 1981-07-31

Family

ID=25175793

Family Applications (5)

Application Number Title Priority Date Filing Date
PL1978215921A PL117107B1 (en) 1977-05-23 1978-05-18 Process for preparing novel 4a,9b-trans-5-aryl-2,3,4,4a,5,9b-hexahydro-1h-pyrido/4,3-b/indoles-geksagirdid 1h-pirido 4,3-b ionidolov
PL1978215923A PL116944B1 (en) 1977-05-23 1978-05-18 Process for preparing novel 4a,9b-trans-5-aryl-2,3,4,4a,5,9b-hexahydro-1h-pyrido/4,3-b/indoles,9b-geksagidro-1h-pirido/4,3-b/indolov
PL1978215922A PL114541B1 (en) 1977-05-23 1978-05-18 Process for preparing novel,substituted in position 2,4a,9b-trans-5-aryl-2,3,4,4a,5,9b-hexahydro-1h-pyrido/4,3-b/indoles
PL1978206903A PL114547B1 (en) 1977-05-23 1978-05-18 Process for preparing novel,substituted in position 2,4a,9b-trans-5-aryl-2,3,4,4a,5,9b-hexahydro-1h-pyrido/4,3-b/indoles
PL20690379A PL206903A1 (pl) 1977-05-23 1979-05-18 Sposob wytwarzania nowych podstawionych w pozycji 2-4a,9b-trans-5-arylo-2,3,4,4a,5a,9b-szesciowodoro-1h-pirydo(4,3-b)indoli

Family Applications After (4)

Application Number Title Priority Date Filing Date
PL1978215923A PL116944B1 (en) 1977-05-23 1978-05-18 Process for preparing novel 4a,9b-trans-5-aryl-2,3,4,4a,5,9b-hexahydro-1h-pyrido/4,3-b/indoles,9b-geksagidro-1h-pirido/4,3-b/indolov
PL1978215922A PL114541B1 (en) 1977-05-23 1978-05-18 Process for preparing novel,substituted in position 2,4a,9b-trans-5-aryl-2,3,4,4a,5,9b-hexahydro-1h-pyrido/4,3-b/indoles
PL1978206903A PL114547B1 (en) 1977-05-23 1978-05-18 Process for preparing novel,substituted in position 2,4a,9b-trans-5-aryl-2,3,4,4a,5,9b-hexahydro-1h-pyrido/4,3-b/indoles
PL20690379A PL206903A1 (pl) 1977-05-23 1979-05-18 Sposob wytwarzania nowych podstawionych w pozycji 2-4a,9b-trans-5-arylo-2,3,4,4a,5a,9b-szesciowodoro-1h-pirydo(4,3-b)indoli

Country Status (31)

Country Link
JP (1) JPS53144600A (de)
AR (2) AR217688A1 (de)
AT (1) AT368995B (de)
AU (1) AU499618B1 (de)
BE (1) BE867249A (de)
CA (1) CA1094071A (de)
CH (1) CH634321A5 (de)
CS (1) CS207612B2 (de)
DD (4) DD146186A5 (de)
DE (1) DE2822465C2 (de)
DK (1) DK226678A (de)
EG (1) EG13590A (de)
FI (1) FI63402C (de)
FR (1) FR2392023A1 (de)
GB (1) GB1586655A (de)
GR (1) GR69985B (de)
HU (3) HU187782B (de)
IE (1) IE46975B1 (de)
IL (1) IL54755A (de)
IT (1) IT1096307B (de)
LU (1) LU79684A1 (de)
NL (1) NL7804210A (de)
NO (2) NO150204C (de)
NZ (1) NZ187333A (de)
PH (1) PH13756A (de)
PL (5) PL117107B1 (de)
PT (1) PT68058B (de)
SE (2) SE441448B (de)
SU (4) SU873883A3 (de)
YU (4) YU91478A (de)
ZA (1) ZA782918B (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4224329A (en) * 1979-01-23 1980-09-23 Pfizer Inc. 2-Substituted-trans-5-aryl-2,3,4,4a,5,9b-hexahydro-1H-pyrido[4,3-b]indoles
US4451655A (en) * 1982-05-17 1984-05-29 Pfizer Inc. Process for preparing carboline derivatives and compounds used in their preparation
RU2106864C1 (ru) * 1995-10-23 1998-03-20 Николай Серафимович Зефиров Средство для лечения болезни альцгеймера
US6974825B1 (en) 1996-12-20 2005-12-13 Astrazeneca Canada Inc. Compounds with analgesic effect
SE9604786D0 (sv) 1996-12-20 1996-12-20 Astra Pharma Inc New compounds
SE9904675D0 (sv) 1999-12-20 1999-12-20 Astra Pharma Inc Novel compounds
SE0101769D0 (sv) 2001-05-18 2001-05-18 Astrazeneca Ab Novel compounds
SE0101771D0 (sv) 2001-05-18 2001-05-18 Astrazeneca Ab Novel compounds
SE0101770D0 (sv) 2001-05-18 2001-05-18 Astrazeneca Ab Novel compounds
SE0101773D0 (sv) 2001-05-18 2001-05-18 Astrazeneca Ab Novel compounds

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR205452A1 (es) * 1973-12-06 1976-05-07 Endo Lab Metodo para preparar nuevos trans-2, 3, 4, 4a, 5, 9b-hexahidro-5-fenil-1h-pirido(4,3-b) indoles
JPS50126699A (de) * 1974-03-20 1975-10-04
US4001263A (en) * 1974-04-01 1977-01-04 Pfizer Inc. 5-Aryl-1,2,3,4-tetrahydro-γ-carbolines

Also Published As

Publication number Publication date
NO151862B (no) 1985-03-11
FR2392023A1 (fr) 1978-12-22
FI63402C (fi) 1983-06-10
AR217688A1 (es) 1980-04-15
YU221782A (en) 1983-01-21
FR2392023B1 (de) 1980-11-07
DD145536A5 (de) 1980-12-17
YU221882A (en) 1983-01-21
HU185009B (en) 1984-11-28
IL54755A (en) 1981-02-27
AR221721A1 (es) 1981-03-13
CS207612B2 (en) 1981-08-31
SU818484A3 (ru) 1981-03-30
PL114547B1 (en) 1981-02-28
YU221682A (en) 1983-01-21
PL116944B1 (en) 1981-07-31
NL7804210A (nl) 1978-11-27
SE8305917L (sv) 1983-10-27
PT68058B (en) 1979-10-24
SU841589A3 (ru) 1981-06-23
JPS5711912B2 (de) 1982-03-08
IT1096307B (it) 1985-08-26
BE867249A (fr) 1978-11-20
PL206903A1 (pl) 1979-10-22
SE7803625L (sv) 1978-11-24
CH634321A5 (en) 1983-01-31
YU40796B (en) 1986-06-30
AU499618B1 (en) 1979-04-26
IT7823673A0 (it) 1978-05-22
NO151862C (no) 1985-06-19
IL54755A0 (en) 1978-07-31
PT68058A (en) 1978-06-01
LU79684A1 (fr) 1979-12-06
HU187782B (en) 1986-02-28
SU873883A3 (ru) 1981-10-15
DE2822465C2 (de) 1986-08-28
YU91478A (en) 1983-01-21
SE8305917D0 (sv) 1983-10-27
PL114541B1 (en) 1981-02-28
SU843749A3 (ru) 1981-06-30
IE46975B1 (en) 1983-11-16
FI63402B (fi) 1983-02-28
IE781013L (en) 1978-11-23
ATA369678A (de) 1982-04-15
NO150204C (no) 1984-09-05
GR69985B (de) 1982-07-22
NO150204B (no) 1984-05-28
HU188802B (en) 1986-05-28
ZA782918B (en) 1979-06-27
EG13590A (en) 1982-03-31
GB1586655A (en) 1981-03-25
NO831790L (no) 1978-11-24
AT368995B (de) 1982-11-25
CA1094071A (en) 1981-01-20
DD145537A5 (de) 1980-12-17
SE441448B (sv) 1985-10-07
DK226678A (da) 1978-11-24
SE448459B (sv) 1987-02-23
JPS53144600A (en) 1978-12-15
DE2822465A1 (de) 1978-11-30
NO781770L (no) 1978-11-24
NZ187333A (en) 1984-05-31
DD146186A5 (de) 1981-01-28
DD138321A5 (de) 1979-10-24
FI781612A7 (fi) 1978-11-24
PH13756A (en) 1980-09-17

Similar Documents

Publication Publication Date Title
Harbert et al. Neuroleptic activity in 5-aryltetrahydro-. gamma.-carbolines
DE69937077T2 (de) Zwischenprodukte für die Herstellung von Imidazo-Pyridin-Derivate
FI80883C (fi) Foerfarande foer framstaellning av nya terapeutiskt anvaendbara bensotiazol- och bensotiofenderivat.
Thompson et al. Synthesis and pharmacological evaluation of a series of dibenzo [a, d] cycloalkenimines as N-methyl-D-aspartate antagonists
AU680320B2 (en) Morpholine derivatives as dopamine receptor subtype ligands
Stanton et al. Synthesis and anticonvulsant activity of some tetracyclic indole derivatives
PL117107B1 (en) Process for preparing novel 4a,9b-trans-5-aryl-2,3,4,4a,5,9b-hexahydro-1h-pyrido/4,3-b/indoles-geksagirdid 1h-pirido 4,3-b ionidolov
AU694212B2 (en) Benzofuran derivatives as d4 receptor antagonists
CA1332836C (en) 3-oxadiazole and 3-carboxylic acid .beta.-carboline derivatives, their production and their use as drugs
JPH08319290A (ja) イミダゾール誘導体
DE60223227T2 (de) BenzoÄbÄthiophenderivate und Verfahren zu deren Herstellung
PL96534B1 (pl) Sposob wytwarzania nowych dwubenzo/b,f/tiepin
DD258984A5 (de) Verfahren zur herstellung neuer heterozyklischer carboxamid-derivate
GB2219798A (en) 2-arycalicyl-pyridine derivatives
Asselin et al. Cycloalkanoindoles. 2. 1-Alkyl-1, 2, 3, 4-tetrahydrocarbazole-1-ethanamines and related compounds. Potential antidepressants
BG99253A (en) Epi - epibatydine derivatives
HU214869B (hu) Eljárás 11-helyettesített-20,21-dinoreburnamenin-származékok és a vegyületeket tartalmazó gyógyászati készítmények előállítására
CZ294957B6 (cs) Způsob přípravy substituované imidazopyridinové sloučeniny
IE883136L (en) Ó(2)-adreno receptor antagonists
PL130655B1 (en) Process for preparing novel condensed derivatives of as-triazine
US3503990A (en) 6-aryl-4,5,6,7-tetrahydro-4-oxoindole derivatives
EP0017727A1 (de) Polysubstituierte Diazatricyclen, Verfahren zu ihrer Herstellung und sie enthaltende pharmazeutische Zusammensetzungen
CA1133483A (en) Hexahydro-trans-pyridoindole neuroleptic agents
GB2160200A (en) Naphth-(2,3-b)-1,4-oxazines
EP1179532B1 (de) Verfahren zur herstellung von indol-derivaten und intermediaten dafür