PL145814B1 - Method of obtaining novel condensed derivatives of double-ring imidazole - Google Patents
Method of obtaining novel condensed derivatives of double-ring imidazole Download PDFInfo
- Publication number
- PL145814B1 PL145814B1 PL1985259305A PL25930585A PL145814B1 PL 145814 B1 PL145814 B1 PL 145814B1 PL 1985259305 A PL1985259305 A PL 1985259305A PL 25930585 A PL25930585 A PL 25930585A PL 145814 B1 PL145814 B1 PL 145814B1
- Authority
- PL
- Poland
- Prior art keywords
- compounds
- pyridine
- formula
- evaporated
- alkyl
- Prior art date
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/84—Nitriles
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/30—Oestrogens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/55—Acids; Esters
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/10—Compounds having one or more C—Si linkages containing nitrogen having a Si-N linkage
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1804—Compounds having Si-O-C linkages
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Endocrinology (AREA)
- Diabetes (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/622,421 US4617307A (en) | 1984-06-20 | 1984-06-20 | Substituted imidazo[1,5-A]pyridine derivatives as aromatase inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL145814B1 true PL145814B1 (en) | 1988-11-30 |
Family
ID=24494112
Family Applications (6)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL1985259305A PL145814B1 (en) | 1984-06-20 | 1985-06-20 | Method of obtaining novel condensed derivatives of double-ring imidazole |
| PL1985259307A PL145105B1 (en) | 1984-06-20 | 1985-06-20 | Method of obtaining novel concentrated two-ring derivatives of imidazole |
| PL1985259303A PL145103B1 (en) | 1984-06-20 | 1985-06-20 | Method of obtaining novel concentrated two-ring derivatives of imidazole |
| PL1985254099A PL145087B1 (en) | 1984-06-20 | 1985-06-20 | Method of obtaining novel derivatives of imidazo /1,5-a/ pyridine |
| PL1985259304A PL145348B1 (en) | 1984-06-20 | 1985-06-20 | Method of obtaining novel condensed disubstituted imidazole derivatives |
| PL1985259306A PL145104B1 (en) | 1984-06-20 | 1985-06-20 | Method of obtaining novel concentrated two-ring derivatives of imidazole |
Family Applications After (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL1985259307A PL145105B1 (en) | 1984-06-20 | 1985-06-20 | Method of obtaining novel concentrated two-ring derivatives of imidazole |
| PL1985259303A PL145103B1 (en) | 1984-06-20 | 1985-06-20 | Method of obtaining novel concentrated two-ring derivatives of imidazole |
| PL1985254099A PL145087B1 (en) | 1984-06-20 | 1985-06-20 | Method of obtaining novel derivatives of imidazo /1,5-a/ pyridine |
| PL1985259304A PL145348B1 (en) | 1984-06-20 | 1985-06-20 | Method of obtaining novel condensed disubstituted imidazole derivatives |
| PL1985259306A PL145104B1 (en) | 1984-06-20 | 1985-06-20 | Method of obtaining novel concentrated two-ring derivatives of imidazole |
Country Status (31)
| Country | Link |
|---|---|
| US (1) | US4617307A (2) |
| EP (1) | EP0165904B1 (2) |
| JP (1) | JPS6112688A (2) |
| KR (1) | KR900008566B1 (2) |
| AT (1) | ATE62415T1 (2) |
| AU (1) | AU589565B2 (2) |
| BG (7) | BG60262B2 (2) |
| CA (1) | CA1276633C (2) |
| CS (1) | CS268672B2 (2) |
| CY (1) | CY1750A (2) |
| DD (1) | DD237510A5 (2) |
| DE (1) | DE3582452D1 (2) |
| DK (1) | DK170302B1 (2) |
| DZ (1) | DZ799A1 (2) |
| ES (6) | ES8702406A1 (2) |
| FI (1) | FI80694C (2) |
| GR (1) | GR851487B (2) |
| HK (1) | HK23494A (2) |
| HU (1) | HU202529B (2) |
| IE (1) | IE58070B1 (2) |
| IL (1) | IL75546A (2) |
| MA (1) | MA20459A1 (2) |
| MX (1) | MX9203369A (2) |
| NO (1) | NO162467C (2) |
| NZ (1) | NZ212483A (2) |
| PH (1) | PH23390A (2) |
| PL (6) | PL145814B1 (2) |
| PT (1) | PT80661B (2) |
| RO (1) | RO92583A (2) |
| SU (6) | SU1433413A3 (2) |
| ZA (1) | ZA854615B (2) |
Families Citing this family (66)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5428160A (en) * | 1982-12-21 | 1995-06-27 | Ciba-Geigy Corporation | Substituted imidazo[5-a]pyridine derviatives and other substituted bicyclic derivatives |
| US4728645A (en) * | 1982-12-21 | 1988-03-01 | Ciba-Geigy Corporation | Substituted imidazo[1,5-A]pyridine derivatives and other substituted bicyclic derivatives, useful as aromatase inhibitors |
| US4889861A (en) * | 1982-12-21 | 1989-12-26 | Ciba-Geigy Corp. | Substituted imidazo[1,5-a]pyridine derivatives and other substituted bicyclic derivatives and their use as aromatase inhibitors |
| GB8510541D0 (en) * | 1985-04-25 | 1985-05-30 | Wyeth John & Brother Ltd | Heterocyclic compounds |
| US5171858A (en) * | 1985-06-05 | 1992-12-15 | Schering A.G. | Preparation of certain 5,6-dihydro-8-phenyl-imidazo[1,5-a]pyridines |
| US4978672A (en) * | 1986-03-07 | 1990-12-18 | Ciba-Geigy Corporation | Alpha-heterocyclc substituted tolunitriles |
| US4749713A (en) * | 1986-03-07 | 1988-06-07 | Ciba-Geigy Corporation | Alpha-heterocycle substituted tolunitriles |
| US4937250A (en) * | 1988-03-07 | 1990-06-26 | Ciba-Geigy Corporation | Alpha-heterocycle substituted tolunitriles |
| US4797411A (en) * | 1986-07-18 | 1989-01-10 | Farmitalia Carlo Erba S.P.A. | Cycloalkyl-substituted 4-pyridyl derivatives and use as aromatase inhibitors |
| GB8820730D0 (en) * | 1988-09-02 | 1988-10-05 | Erba Carlo Spa | Substituted 5 6 7 8-tetrahydroimidazo/1.5-a/pyridines & process for their preparation |
| US5057521A (en) * | 1988-10-26 | 1991-10-15 | Ciba-Geigy Corporation | Use of bicyclic imidazole compounds for the treatment of hyperaldosteronism |
| US5066656A (en) * | 1989-11-01 | 1991-11-19 | Janssen Pharmaceutica N.V. | Pharmacologically active (6,7-dihydro-5H-pyrrolo[1,2-c]imidazol-5-yl)- and (5,6,7,8-tetrahydroimidazo[1,5-a]pyridin-5-yl) substituted 1H-benzotriazole derivatives |
| CA2026792A1 (en) * | 1989-11-01 | 1991-05-02 | Michael N. Greco | (6,7-dihydro-5h-pyrrolo[1,2-c]imidazol-5-yl)- and (5,6,7,8-tetrahydroimidazo[1,5-a]pyridin-5-yl) substituted 1h-benzotriazole derivatives |
| MTP1076B (en) * | 1990-01-12 | 1991-09-30 | Ciba Geigy Ag | Hemihydrate |
| US5162337A (en) * | 1990-10-05 | 1992-11-10 | Merck & Co., Inc. | Animal growth promotion |
| EP0514015A1 (en) * | 1991-04-19 | 1992-11-19 | Merck & Co. Inc. | Control of sex differentiation in fish |
| CH683151A5 (de) * | 1991-04-24 | 1994-01-31 | Ciba Geigy Ag | Antikonzeption bei weiblichen Primaten ohne Beeinflussung des menstruellen Zyklus. |
| JPH05176659A (ja) * | 1991-04-26 | 1993-07-20 | Merck & Co Inc | 家禽における雌性表現型を転換するために抗ミュラー管ホルモンを単独またはアロマターゼ阻害剤と組合せて使用する方法 |
| AU2356195A (en) * | 1994-04-14 | 1995-11-10 | Sepracor, Inc. | Treating estrogen-dependent diseases with (-)-fadrozole |
| AU682947B2 (en) * | 1994-05-27 | 1997-10-23 | Mochida Pharmaceutical Co., Ltd. | Novel azolyl methyl phenyl derivatives having aromatase inhibitory activity |
| DE4432106A1 (de) * | 1994-09-09 | 1996-03-14 | Hoechst Ag | Mit Heterocyclen-N-Oxid-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum, sie enthaltendes Medikament sowie Zwischenprodukte zu ihrer Herstellung |
| US6833373B1 (en) | 1998-12-23 | 2004-12-21 | G.D. Searle & Co. | Method of using an integrin antagonist and one or more antineoplastic agents as a combination therapy in the treatment of neoplasia |
| US6858598B1 (en) | 1998-12-23 | 2005-02-22 | G. D. Searle & Co. | Method of using a matrix metalloproteinase inhibitor and one or more antineoplastic agents as a combination therapy in the treatment of neoplasia |
| US8168616B1 (en) | 2000-11-17 | 2012-05-01 | Novartis Ag | Combination comprising a renin inhibitor and an angiotensin receptor inhibitor for hypertension |
| AU2003250190A1 (en) * | 2002-07-30 | 2004-02-23 | Novartis Ag | Combination of an aromatase inhibitor with a bisphosphonate |
| EP1537114B8 (en) * | 2002-08-07 | 2007-10-03 | Novartis AG | Organic compounds as agents for the treatment of aldosterone mediated conditions |
| WO2004046145A1 (en) * | 2002-11-18 | 2004-06-03 | Novartis Ag | Imidazo[1, 5a]pyridine derivatives and methods for treating aldosterone mediated diseases |
| WO2005007627A1 (ja) * | 2003-07-18 | 2005-01-27 | Nihon Nohyaku Co., Ltd. | フェニルピリジン誘導体、その中間体及びこれを有効成分とする除草剤 |
| GB0327839D0 (en) | 2003-12-01 | 2003-12-31 | Novartis Ag | Organic compounds |
| NZ549535A (en) | 2004-03-17 | 2010-11-26 | Novartis Ag | Use of aliskiren for treating renal and other disorders |
| CN1997643A (zh) * | 2004-05-28 | 2007-07-11 | 斯皮德尔实验股份公司 | 杂环化合物及其作为醛固酮合酶抑制剂的应用 |
| CA2568159A1 (en) * | 2004-05-28 | 2005-12-15 | Speedel Experimenta Ag | Tetrahydro-imidazo [1,5-a] pyridin derivatives as aldosterone synthase inhibitors |
| GT200600381A (es) | 2005-08-25 | 2007-03-28 | Compuestos organicos | |
| EP1842543A1 (en) | 2006-04-05 | 2007-10-10 | Speedel Pharma AG | Pharmaceutical composition coprising an aldosterone synthase inhibitor and a mineralcorticoid receptor antagonist |
| MX2008015008A (es) * | 2006-05-26 | 2008-12-05 | Novartis Ag | INHIBIDORES DE SINTASA DE ALDOSTERONA Y/O DE 11ß-HIDROXILASA. |
| CA2657258A1 (en) | 2006-07-20 | 2008-01-24 | Novartis Ag | Amino-piperidine derivatives as cetp inhibitors |
| JP2010501573A (ja) * | 2006-08-25 | 2010-01-21 | ノバルティス アクチエンゲゼルシャフト | アルドステロン合成酵素および/または11−β−ヒドロキシラーゼおよび/またはアロマターゼが介在する疾患の処置のための縮合イミダゾール誘導体 |
| WO2008085302A1 (en) * | 2006-12-20 | 2008-07-17 | Merck & Co., Inc. | Imidazopyridine analogs as cb2 receptor modulators, useful in the treatment of pain, respiratory and non-respiratory diseases |
| EP2463282B1 (en) | 2007-11-05 | 2013-08-07 | Novartis AG | 4-Benzylamino-1-carboxyacyl-piperidine derivatives as CETP inhibitors useful for the treatment of diseases such as hyperlipidemia or arteriosclerosis |
| MX2010006063A (es) | 2007-12-03 | 2010-07-01 | Novartis Ag | Derivados de 4-bencil-amino-pirrolidina 1,2-disustituida como inhibidores de la proteina de transferencia de colesteril-ester (cetp) utiles para el tratamiento de las enfermedades tales como hiperlipidemia o arterioesclerosis. |
| EP2095819A1 (en) * | 2008-02-28 | 2009-09-02 | Maastricht University | N-benzyl imidazole derivatives and their use as aldosterone synthase inhibitors |
| CN103896796B (zh) | 2009-05-28 | 2016-04-27 | 诺华股份有限公司 | 作为脑啡肽酶抑制剂的取代的氨基丙酸衍生物 |
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| JO2967B1 (en) | 2009-11-20 | 2016-03-15 | نوفارتس ايه جي | Acetic acid derivatives of carbamoyl methyl amino are substituted as new NEP inhibitors |
| US8877815B2 (en) | 2010-11-16 | 2014-11-04 | Novartis Ag | Substituted carbamoylcycloalkyl acetic acid derivatives as NEP |
| US8673974B2 (en) | 2010-11-16 | 2014-03-18 | Novartis Ag | Substituted amino bisphenyl pentanoic acid derivatives as NEP inhibitors |
| AR086665A1 (es) | 2011-06-14 | 2014-01-15 | Lilly Co Eli | Inhibidor de aldosterona sintasa y composiciones farmaceuticas |
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| JO3137B1 (ar) | 2012-01-17 | 2017-09-20 | Novartis Ag | أملاح وأشكال جديدة لمثبط إنزيم سينثاز أو أروماتاز ثنائي هيدروبيرولو [2،1-c] إيميدازوليل ألدوستيرون |
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| MX2017009839A (es) * | 2015-01-29 | 2017-11-02 | Novartis Ag | Proceso para la produccion de derivados de imidazolo condensados. |
| GB201511790D0 (en) | 2015-07-06 | 2015-08-19 | Iomet Pharma Ltd | Pharmaceutical compound |
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| CN109890389B (zh) * | 2016-10-27 | 2022-07-01 | 达米安制药股份公司 | 醛固酮合酶抑制剂 |
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| UY38072A (es) | 2018-02-07 | 2019-10-01 | Novartis Ag | Compuestos derivados de éster butanoico sustituido con bisfenilo como inhibidores de nep, composiciones y combinaciones de los mismos |
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| JP7657151B2 (ja) | 2018-11-27 | 2025-04-04 | ノバルティス アーゲー | 代謝性障害の処置のためのプロタンパク質コンバターゼスブチリシン/ケキシン9型(pcsk9)阻害剤としての環状ペプチド |
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| WO2023084449A1 (en) | 2021-11-12 | 2023-05-19 | Novartis Ag | Diaminocyclopentylpyridine derivatives for the treatment of a disease or disorder |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5124517B1 (2) * | 1971-03-15 | 1976-07-24 | ||
| FR2449689A1 (fr) * | 1979-02-20 | 1980-09-19 | Logeais Labor Jacques | Nouveaux derives condenses de pyrrolidine ou de piperidine, leur procede de preparation et leurs applications en therapeutique |
| US4444775A (en) * | 1981-06-22 | 1984-04-24 | Ciba-Geigy Corporation | Substituted imidazo[1,5-A]pyridines |
| FI75569C (fi) * | 1981-06-22 | 1988-07-11 | Ciba Geigy Ag | Analogifoerfarande foer framstaellning av terapeutiskt verkande imidazo/1,5-a/pyridiner. |
| US4409226A (en) * | 1981-10-05 | 1983-10-11 | Schering Corporation | Imidazo[1,5-a]pyridines |
| US4361567A (en) * | 1981-10-05 | 1982-11-30 | Schering Corporation | Treatment of peptic ulcer disease |
| US4588732A (en) * | 1982-12-21 | 1986-05-13 | Ciba-Geigy Corporation | Certain imidazo(1,5-a)pyridine derivatives and their use as thromboxane synthetase inhibitors |
| US4470986A (en) * | 1982-12-21 | 1984-09-11 | Ciba-Geigy Corporation | Certain imidazo (1,5-A) pyridine aliphatic carboxylic acid derivatives and their use as selective thromboxane inhibitors |
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1984
- 1984-06-20 US US06/622,421 patent/US4617307A/en not_active Expired - Lifetime
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1985
- 1985-06-17 AT AT85810279T patent/ATE62415T1/de not_active IP Right Cessation
- 1985-06-17 EP EP85810279A patent/EP0165904B1/de not_active Expired - Lifetime
- 1985-06-17 DE DE8585810279T patent/DE3582452D1/de not_active Expired - Lifetime
- 1985-06-17 FI FI852399A patent/FI80694C/fi not_active IP Right Cessation
- 1985-06-18 CA CA000484263A patent/CA1276633C/en not_active Expired - Lifetime
- 1985-06-18 DZ DZ850130A patent/DZ799A1/fr active
- 1985-06-18 GR GR851487A patent/GR851487B/el unknown
- 1985-06-18 IL IL75546A patent/IL75546A/xx not_active IP Right Cessation
- 1985-06-18 CS CS854449A patent/CS268672B2/cs not_active IP Right Cessation
- 1985-06-19 RO RO85119210A patent/RO92583A/ro unknown
- 1985-06-19 PH PH32427A patent/PH23390A/en unknown
- 1985-06-19 PT PT80661A patent/PT80661B/pt unknown
- 1985-06-19 DK DK277685A patent/DK170302B1/da not_active IP Right Cessation
- 1985-06-19 ZA ZA854615A patent/ZA854615B/xx unknown
- 1985-06-19 AU AU43857/85A patent/AU589565B2/en not_active Expired
- 1985-06-19 HU HU852417A patent/HU202529B/hu unknown
- 1985-06-19 IE IE152085A patent/IE58070B1/en not_active IP Right Cessation
- 1985-06-19 ES ES544344A patent/ES8702406A1/es not_active Expired
- 1985-06-19 KR KR1019850004323A patent/KR900008566B1/ko not_active Expired
- 1985-06-19 MA MA20686A patent/MA20459A1/fr unknown
- 1985-06-19 NZ NZ212483A patent/NZ212483A/xx unknown
- 1985-06-19 SU SU853917403A patent/SU1433413A3/ru active
- 1985-06-19 BG BG70749A patent/BG60262B2/xx unknown
- 1985-06-19 NO NO852474A patent/NO162467C/no unknown
- 1985-06-20 PL PL1985259305A patent/PL145814B1/pl unknown
- 1985-06-20 JP JP60133167A patent/JPS6112688A/ja active Granted
- 1985-06-20 PL PL1985259307A patent/PL145105B1/pl unknown
- 1985-06-20 PL PL1985259303A patent/PL145103B1/pl unknown
- 1985-06-20 PL PL1985254099A patent/PL145087B1/pl unknown
- 1985-06-20 PL PL1985259304A patent/PL145348B1/pl unknown
- 1985-06-20 DD DD85277587A patent/DD237510A5/de not_active IP Right Cessation
- 1985-06-20 PL PL1985259306A patent/PL145104B1/pl unknown
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1986
- 1986-05-30 ES ES555542A patent/ES8802049A1/es not_active Expired
- 1986-05-30 ES ES555538A patent/ES8802048A1/es not_active Expired
- 1986-05-30 ES ES555540A patent/ES8801262A1/es not_active Expired
- 1986-05-30 ES ES555539A patent/ES8802155A1/es not_active Expired
- 1986-05-30 ES ES555541A patent/ES8800681A1/es not_active Expired
- 1986-07-02 SU SU864027755A patent/SU1436879A3/ru active
- 1986-07-02 SU SU864027757A patent/SU1436880A3/ru active
- 1986-07-02 SU SU864027756A patent/SU1482530A3/ru active
- 1986-07-02 SU SU864027758A patent/SU1443802A3/ru active
- 1986-07-02 SU SU864027754A patent/SU1436878A3/ru active
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1992
- 1992-06-25 MX MX9203369A patent/MX9203369A/es unknown
- 1992-10-22 BG BG097009A patent/BG60305B2/bg unknown
- 1992-10-22 BG BG097010A patent/BG60306B2/bg unknown
- 1992-10-22 BG BG097011A patent/BG60307B2/xx unknown
- 1992-10-22 BG BG097012A patent/BG60352B2/bg unknown
- 1992-10-22 BG BG097013A patent/BG60353B2/bg unknown
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1993
- 1993-11-11 BG BG098213A patent/BG60402B2/bg unknown
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1994
- 1994-03-17 HK HK234/94A patent/HK23494A/xx not_active IP Right Cessation
- 1994-06-03 CY CY175094A patent/CY1750A/xx unknown
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