PL1606261T3 - Nowy sposób przygotowania roflumilastu - Google Patents

Nowy sposób przygotowania roflumilastu

Info

Publication number: PL1606261T3
Authority: PL; Poland
Prior art keywords: roflumilast; preparation; novel process; novel
Prior art date: 2003-03-10

Application number

PL04718315T

Other languages

English (en)

Inventor

Bernhard Kohl

Bernd Mueller

Walter Palosch

Original Assignee

Astrazeneca Ab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2003-03-10

Filing date

2004-03-08

Publication date

2010-04-30

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=32981730&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL1606261(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2004-03-08 Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab

2010-04-30 Publication of PL1606261T3 publication Critical patent/PL1606261T3/pl

Links

MNDBXUUTURYVHR-UHFFFAOYSA-N roflumilast Chemical compound FC(F)OC1=CC=C(C(=O)NC=2C(=CN=CC=2Cl)Cl)C=C1OCC1CC1 MNDBXUUTURYVHR-UHFFFAOYSA-N 0.000 title 1
229960002586 roflumilast Drugs 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/61—Halogen atoms or nitro radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/75—Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Epidemiology (AREA)
Orthopedic Medicine & Surgery (AREA)
Immunology (AREA)
Rheumatology (AREA)
Physical Education & Sports Medicine (AREA)
Dermatology (AREA)
Pulmonology (AREA)
Pyridine Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

PL04718315T 2003-03-10 2004-03-08 Nowy sposób przygotowania roflumilastu PL1606261T3 (pl)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
EP03005245		2003-03-10
PCT/EP2004/050272 WO2004080967A1 (en)	2003-03-10	2004-03-08	Novel process for the preparation of roflumilast
EP04718315A EP1606261B1 (en)	2003-03-10	2004-03-08	Novel process for the preparation of roflumilast

Publications (1)

Publication Number	Publication Date
PL1606261T3 true PL1606261T3 (pl)	2010-04-30

Family

ID=32981730

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PL04718315T PL1606261T3 (pl)	2003-03-10	2004-03-08	Nowy sposób przygotowania roflumilastu

Country Status (29)

Country	Link
US (5)	US7470791B2 (pl)
EP (1)	EP1606261B1 (pl)
JP (1)	JP4742026B2 (pl)
KR (1)	KR101179012B1 (pl)
CN (1)	CN100471840C (pl)
AR (1)	AR043531A1 (pl)
AT (1)	ATE447555T1 (pl)
AU (1)	AU2004220357B2 (pl)
BR (1)	BRPI0406427B8 (pl)
CA (1)	CA2503290C (pl)
CY (1)	CY1109580T1 (pl)
DE (1)	DE602004023921D1 (pl)
DK (1)	DK1606261T3 (pl)
EA (1)	EA009985B1 (pl)
ES (1)	ES2335498T3 (pl)
HR (1)	HRP20050399B1 (pl)
IL (1)	IL168170A (pl)
IS (1)	IS2723B (pl)
ME (1)	ME00524B (pl)
MX (1)	MXPA04008070A (pl)
NO (1)	NO329301B1 (pl)
NZ (1)	NZ539542A (pl)
PL (1)	PL1606261T3 (pl)
PT (1)	PT1606261E (pl)
RS (2)	RS52908B (pl)
SI (1)	SI1606261T1 (pl)
TW (1)	TWI340741B (pl)
WO (1)	WO2004080967A1 (pl)
ZA (1)	ZA200503191B (pl)

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CN103319333B (zh) *	2013-07-15	2014-12-10	天津南开允公医药科技有限公司	一种制备3-环丙基甲氧基-4-二氟甲氧基苯甲酰氯化合物的方法
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CN103536582A (zh) *	2013-10-12	2014-01-29	云南龙海天然植物药业有限公司	罗氟司特干粉吸入剂
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2004
- 2004-03-08 ES ES04718315T patent/ES2335498T3/es not_active Expired - Lifetime
- 2004-03-08 EP EP04718315A patent/EP1606261B1/en not_active Expired - Lifetime
- 2004-03-08 JP JP2006505451A patent/JP4742026B2/ja not_active Expired - Fee Related
- 2004-03-08 RS RS20050669A patent/RS52908B/sr unknown
- 2004-03-08 DE DE602004023921T patent/DE602004023921D1/de not_active Expired - Lifetime
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- 2004-03-08 DK DK04718315.7T patent/DK1606261T3/da active
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- 2004-03-08 AT AT04718315T patent/ATE447555T1/de active
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- 2004-03-08 EA EA200501350A patent/EA009985B1/ru active Protection Beyond IP Right Term
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2005
- 2005-04-19 IS IS7810A patent/IS2723B/is unknown
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2008
- 2008-11-26 US US12/292,795 patent/US20090171096A1/en not_active Abandoned
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2012
- 2012-07-12 US US13/547,945 patent/US8536206B2/en not_active Expired - Fee Related
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Also Published As

Publication number	Publication date
AU2004220357B2 (en)	2010-09-30
BRPI0406427A (pt)	2005-10-04
BRPI0406427B8 (pt)	2021-05-25
US20130231374A1 (en)	2013-09-05
DK1606261T3 (da)	2010-01-18
NZ539542A (en)	2007-09-28
TW200508201A (en)	2005-03-01
US8536206B2 (en)	2013-09-17
US20130224299A1 (en)	2013-08-29
US8618142B2 (en)	2013-12-31
RS52908B (sr)	2014-02-28
IL168170A (en)	2010-12-30
JP4742026B2 (ja)	2011-08-10
CY1109580T1 (el)	2014-08-13
DE602004023921D1 (de)	2009-12-17
NO20051957D0 (no)	2005-04-21
WO2004080967A1 (en)	2004-09-23
AR043531A1 (es)	2005-08-03
HRP20050399A2 (en)	2006-08-31
US20120294942A1 (en)	2012-11-22
AU2004220357A1 (en)	2004-09-23
NO20051957L (no)	2005-10-06
BRPI0406427B1 (pt)	2019-05-14
HRP20050399B1 (hr)	2013-09-30
IS2723B (is)	2011-03-15
KR20050106392A (ko)	2005-11-09
US20090171096A1 (en)	2009-07-02
TWI340741B (en)	2011-04-21
CA2503290A1 (en)	2004-09-23
US8604064B2 (en)	2013-12-10
CN100471840C (zh)	2009-03-25
EA009985B1 (ru)	2008-04-28
MXPA04008070A (es)	2004-11-26
ES2335498T3 (es)	2010-03-29
CA2503290C (en)	2012-12-04
PT1606261E (pt)	2010-01-11
RS20050669A (sr)	2008-04-04
ZA200503191B (en)	2006-02-22
EP1606261A1 (en)	2005-12-21
JP2006519818A (ja)	2006-08-31
EP1606261B1 (en)	2009-11-04
EA200501350A1 (ru)	2006-04-28
US7470791B2 (en)	2008-12-30
CN1701062A (zh)	2005-11-23
IS7810A (is)	2005-04-19
ME00524B (me)	2011-10-10
NO329301B1 (no)	2010-09-27
KR101179012B1 (ko)	2012-09-03
SI1606261T1 (sl)	2010-03-31
US20060004061A1 (en)	2006-01-05
HK1085480A1 (zh)	2006-08-25
ATE447555T1 (de)	2009-11-15

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