PL1758871T3 - Pirazolopirymidyny - Google Patents

Pirazolopirymidyny

Info

Publication number
PL1758871T3
PL1758871T3 PL05753794T PL05753794T PL1758871T3 PL 1758871 T3 PL1758871 T3 PL 1758871T3 PL 05753794 T PL05753794 T PL 05753794T PL 05753794 T PL05753794 T PL 05753794T PL 1758871 T3 PL1758871 T3 PL 1758871T3
Authority
PL
Poland
Prior art keywords
cyclin
dependent kinase
treatment
control
pyrazolopyrimidines
Prior art date
Application number
PL05753794T
Other languages
English (en)
Inventor
Qingjie Ding
Nan Jiang
John Lawson Roberts
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of PL1758871T3 publication Critical patent/PL1758871T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
PL05753794T 2004-06-09 2005-06-01 Pirazolopirymidyny PL1758871T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US57825304P 2004-06-09 2004-06-09
EP05753794A EP1758871B1 (en) 2004-06-09 2005-06-01 Pyrazolo pyrimidines
PCT/EP2005/005896 WO2005121107A1 (en) 2004-06-09 2005-06-01 Pyrazolo pyrimidines

Publications (1)

Publication Number Publication Date
PL1758871T3 true PL1758871T3 (pl) 2008-04-30

Family

ID=35170008

Family Applications (1)

Application Number Title Priority Date Filing Date
PL05753794T PL1758871T3 (pl) 2004-06-09 2005-06-01 Pirazolopirymidyny

Country Status (14)

Country Link
US (1) US7405220B2 (pl)
EP (1) EP1758871B1 (pl)
JP (1) JP2008501744A (pl)
CN (1) CN1964954B (pl)
AT (1) ATE378321T1 (pl)
AU (1) AU2005251892A1 (pl)
BR (1) BRPI0511975A (pl)
CA (1) CA2568722A1 (pl)
DE (1) DE602005003362T2 (pl)
ES (1) ES2296195T3 (pl)
MX (1) MXPA06014161A (pl)
PL (1) PL1758871T3 (pl)
RU (1) RU2412186C2 (pl)
WO (1) WO2005121107A1 (pl)

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WO2007125952A1 (ja) 2006-04-28 2007-11-08 Shionogi & Co., Ltd. Ｎｐｙ ｙ５受容体拮抗作用を有するアミン誘導体
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KR100963644B1 (ko) 2007-11-23 2010-06-15 한국과학기술연구원 피라졸로피리미딘온 유도체 및 그의 제조방법
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WO2010118367A2 (en) * 2009-04-10 2010-10-14 Progenics Pharmaceuticals, Inc. Antiviral pyrimidines
US8227618B2 (en) 2009-04-23 2012-07-24 Shionogi & Co., Ltd. Amine-derivatives having NPY Y5 receptor antagonistic activity and the uses thereof
US8362023B2 (en) 2011-01-19 2013-01-29 Hoffmann-La Roche Inc. Pyrazolo pyrimidines
JP2013142065A (ja) 2012-01-10 2013-07-22 Sumitomo Chemical Co Ltd 植物病害防除組成物およびその用途
CN102690270B (zh) * 2012-05-28 2014-02-05 苏州科捷生物医药有限公司 嘧啶类化合物及其用途
CN103058934A (zh) * 2013-01-07 2013-04-24 盛世泰科生物医药技术(苏州)有限公司 一种5-乙酰基-2,4-二氯嘧啶的合成方法
TWI629275B (zh) 2013-03-13 2018-07-11 賽諾菲公司 Ｎ－（４－（氮雜吲唑－６－基）－苯基）－磺醯胺及其作為醫藥之用途
DK3149008T3 (en) * 2014-05-28 2019-04-01 Shanghai Fochon Pharmaceutical Co Ltd Specific protein kinase inhibitors
GB201501115D0 (en) 2015-01-23 2015-03-11 Univ Dundee Compounds
TWI726861B (zh) 2015-01-23 2021-05-11 英商葛蘭素史克智慧財產發展有限公司 吡唑并-嘧啶化合物、其鹽及其用途
DE102016110830B4 (de) 2015-06-14 2022-01-13 Zema - Zentrum Für Mechatronik Und Automatisierungstechnik Gemeinnützige Gmbh Vorrichtung zur Befestigung einer Adaptionsplatte an einer Radnabe eines Fahrzeugs und Verfahren zum Betrieb einer Adaptionsplatte an einer Radnabe eines Fahrzeugs
US12583852B2 (en) 2018-05-02 2026-03-24 Jw Pharmaceutical Corporation Heterocycle derivative
US11066404B2 (en) 2018-10-11 2021-07-20 Incyte Corporation Dihydropyrido[2,3-d]pyrimidinone compounds as CDK2 inhibitors
US11384083B2 (en) 2019-02-15 2022-07-12 Incyte Corporation Substituted spiro[cyclopropane-1,5′-pyrrolo[2,3-d]pyrimidin]-6′(7′h)-ones as CDK2 inhibitors
TW202100520A (zh) 2019-03-05 2021-01-01 美商英塞特公司 作為cdk2 抑制劑之吡唑基嘧啶基胺化合物
WO2020205560A1 (en) 2019-03-29 2020-10-08 Incyte Corporation Sulfonylamide compounds as cdk2 inhibitors
US11447494B2 (en) 2019-05-01 2022-09-20 Incyte Corporation Tricyclic amine compounds as CDK2 inhibitors
WO2020223469A1 (en) 2019-05-01 2020-11-05 Incyte Corporation N-(1-(methylsulfonyl)piperidin-4-yl)-4,5-di hydro-1h-imidazo[4,5-h]quinazolin-8-amine derivatives and related compounds as cyclin-dependent kinase 2 (cdk2) inhibitors for treating cancer
CA3150681A1 (en) 2019-08-14 2021-02-18 Incyte Corporation Imidazolyl pyrimidinylamine compounds as cdk2 inhibitors
US11851426B2 (en) * 2019-10-11 2023-12-26 Incyte Corporation Bicyclic amines as CDK2 inhibitors
WO2021141041A1 (ja) 2020-01-07 2021-07-15 大日本住友製薬株式会社 タウオパチーの治療剤
KR20240020735A (ko) 2021-05-07 2024-02-15 카이메라 쎄라퓨틱스 인코포레이티드 Cdk2 분해제 및 그 용도
US11981671B2 (en) 2021-06-21 2024-05-14 Incyte Corporation Bicyclic pyrazolyl amines as CDK2 inhibitors
US11932648B2 (en) * 2021-06-28 2024-03-19 Blueprint Medicines Corporation CDK2 inhibitors
EP4147700A1 (en) 2021-09-08 2023-03-15 LQT Therapeutics Inc. N-(4-(azaindazol-6-yl)-phenyl)-sulfonamides for use in the treatment of sickle cell disease
US11976073B2 (en) 2021-12-10 2024-05-07 Incyte Corporation Bicyclic amines as CDK2 inhibitors
US12084453B2 (en) 2021-12-10 2024-09-10 Incyte Corporation Bicyclic amines as CDK12 inhibitors
WO2024238570A1 (en) * 2023-05-15 2024-11-21 Aleksia Therapeutics, Inc. Cdk2 inhibitor pyrazolopyrimidine compounds
WO2025024726A1 (en) * 2023-07-26 2025-01-30 Kinnate Biopharma Inc. Inhibitors of cyclin-dependent kinase

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US7157455B2 (en) 2003-02-10 2007-01-02 Hoffmann-La Roche Inc. 4-Aminopyrimidine-5-one derivatives
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CN1934111A (zh) * 2004-02-27 2007-03-21 霍夫曼-拉罗奇有限公司 杂芳基稠合的吡唑并衍生物

Also Published As

Publication number Publication date
US20050277655A1 (en) 2005-12-15
CA2568722A1 (en) 2005-12-22
JP2008501744A (ja) 2008-01-24
RU2007100134A (ru) 2008-07-20
RU2412186C2 (ru) 2011-02-20
DE602005003362D1 (en) 2007-12-27
ES2296195T3 (es) 2008-04-16
DE602005003362T2 (de) 2008-10-16
EP1758871B1 (en) 2007-11-14
US7405220B2 (en) 2008-07-29
ATE378321T1 (de) 2007-11-15
WO2005121107A1 (en) 2005-12-22
EP1758871A1 (en) 2007-03-07
CN1964954A (zh) 2007-05-16
AU2005251892A1 (en) 2005-12-22
MXPA06014161A (es) 2007-01-29
BRPI0511975A (pt) 2008-01-22
CN1964954B (zh) 2010-07-21

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