PL1758905T3 - 8-[3-Aminopiperydyn-1-ylo]-ksantyna, jej wytwarzanie i jej zastosowanie jako inhibitora DPP-IV - Google Patents

8-[3-Aminopiperydyn-1-ylo]-ksantyna, jej wytwarzanie i jej zastosowanie jako inhibitora DPP-IV

Info

Publication number: PL1758905T3
Authority: PL; Poland
Prior art keywords: ddp; xanthine; piperidin; inhibitor; amino
Prior art date: 2004-02-18

Application number

PL05707354T

Other languages

English (en)

Inventor

Frank Himmelsbach

Elke Langkopf

Matthias Eckhardt

Mohammad Tadayyon

Leo Thomas

Original Assignee

Boehringer Ingelheim Int

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2004-02-18

Filing date

2005-02-12

Publication date

2009-10-30

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34922894&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL1758905(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2004-02-18 Priority claimed from DE102004008112A external-priority patent/DE102004008112A1/de

2004-03-17 Priority claimed from DE102004012921A external-priority patent/DE102004012921A1/de

2004-07-03 Priority claimed from DE102004032263A external-priority patent/DE102004032263A1/de

2005-02-12 Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int

2009-10-30 Publication of PL1758905T3 publication Critical patent/PL1758905T3/pl

Links

WNHHLYZOSOUUQW-UHFFFAOYSA-N 8-(3-aminopiperidin-1-yl)-3,7-dihydropurine-2,6-dione Chemical compound C1C(N)CCCN1C(N1)=NC2=C1C(=O)NC(=O)N2 WNHHLYZOSOUUQW-UHFFFAOYSA-N 0.000 title 1
239000003112 inhibitor Substances 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
- C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
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Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Diabetes (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Hematology (AREA)
Endocrinology (AREA)
Immunology (AREA)
Rheumatology (AREA)
Physical Education & Sports Medicine (AREA)
Oncology (AREA)
Urology & Nephrology (AREA)
Orthopedic Medicine & Surgery (AREA)
Pain & Pain Management (AREA)
Virology (AREA)
Obesity (AREA)
Reproductive Health (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Dermatology (AREA)
Psychiatry (AREA)
Communicable Diseases (AREA)
Tropical Medicine & Parasitology (AREA)
Molecular Biology (AREA)
Transplantation (AREA)
Vascular Medicine (AREA)

PL05707354T 2004-02-18 2005-02-12 8-[3-Aminopiperydyn-1-ylo]-ksantyna, jej wytwarzanie i jej zastosowanie jako inhibitora DPP-IV PL1758905T3 (pl)

Applications Claiming Priority (5)

Application Number	Priority Date	Filing Date	Title
DE102004008112A DE102004008112A1 (de)	2004-02-18	2004-02-18	8-[3-Amino-piperidin-1-yl]-xanthine, deren Herstellung und Verwendung als Arzneimittel
DE102004012921A DE102004012921A1 (de)	2004-03-17	2004-03-17	8-[3-Amino-piperidin-1-yl]-xanthine, deren Herstellung und deren Verwendung als Arzneimittel
DE102004032263A DE102004032263A1 (de)	2004-07-03	2004-07-03	8-[3-Amino-piperidin-1yl]-xanthine, deren Herstellung und deren Verwendung als Arzneimittel
EP05707354A EP1758905B1 (de)	2004-02-18	2005-02-12	8-[3-amino-piperidin-1-yl]-xanthine, deren herstellung und deren verwendung als dpp-iv hemmer
PCT/EP2005/001427 WO2005085246A1 (de)	2004-02-18	2005-02-12	8-[3-amino-piperidin-1-yl]-xanthine, deren herstellung und deren verwendung als dpp-iv hemmer

Publications (1)

Publication Number	Publication Date
PL1758905T3 true PL1758905T3 (pl)	2009-10-30

Family

ID=34922894

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PL05707354T PL1758905T3 (pl)	2004-02-18	2005-02-12	8-[3-Aminopiperydyn-1-ylo]-ksantyna, jej wytwarzanie i jej zastosowanie jako inhibitora DPP-IV

Country Status (29)

Country	Link
EP (2)	EP1758905B1 (pl)
JP (2)	JP4733058B2 (pl)
KR (1)	KR101207224B1 (pl)
CN (1)	CN102199151A (pl)
AR (1)	AR047614A1 (pl)
AT (1)	ATE430150T1 (pl)
AU (1)	AU2005219508B2 (pl)
BR (1)	BRPI0507873B8 (pl)
CA (1)	CA2555050C (pl)
CY (1)	CY1109284T1 (pl)
DE (1)	DE502005007196D1 (pl)
DK (1)	DK1758905T3 (pl)
EA (2)	EA010854B1 (pl)
EC (1)	ECSP066775A (pl)
ES (1)	ES2326666T3 (pl)
HR (1)	HRP20090346T1 (pl)
IL (2)	IL176920A (pl)
ME (1)	ME01108B (pl)
MY (1)	MY144322A (pl)
NO (1)	NO20062688L (pl)
NZ (1)	NZ548901A (pl)
PE (1)	PE20060210A1 (pl)
PL (1)	PL1758905T3 (pl)
PT (1)	PT1758905E (pl)
RS (1)	RS50982B (pl)
SI (1)	SI1758905T1 (pl)
TW (1)	TWI350756B (pl)
UY (1)	UY28749A1 (pl)
WO (1)	WO2005085246A1 (pl)

Families Citing this family (93)

* Cited by examiner, † Cited by third party
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US7407955B2 (en)	2002-08-21	2008-08-05	Boehringer Ingelheim Pharma Gmbh & Co., Kg	8-[3-amino-piperidin-1-yl]-xanthines, the preparation thereof and their use as pharmaceutical compositions
US7495005B2 (en)	2002-08-22	2009-02-24	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Xanthine derivatives, their preparation and their use in pharmaceutical compositions
US7569574B2 (en)	2002-08-22	2009-08-04	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Purine derivatives, the preparation thereof and their use as pharmaceutical compositions
US7482337B2 (en)	2002-11-08	2009-01-27	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Xanthine derivatives, the preparation thereof and their use as pharmaceutical compositions
DE10254304A1 (de)	2002-11-21	2004-06-03	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Neue Xanthinderivate, deren Herstellung und deren Verwendung als Arzneimittel
US7566707B2 (en)	2003-06-18	2009-07-28	Boehringer Ingelheim International Gmbh	Imidazopyridazinone and imidazopyridone derivatives, the preparation thereof and their use as pharmaceutical compositions
DE10355304A1 (de)	2003-11-27	2005-06-23	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Neue 8-(Piperazin-1-yl)-und 8-([1,4]Diazepan-1-yl)-xanthine, deren Herstellung und deren Verwendung als Arzneimittel
US7501426B2 (en)	2004-02-18	2009-03-10	Boehringer Ingelheim International Gmbh	8-[3-amino-piperidin-1-yl]-xanthines, their preparation and their use as pharmaceutical compositions
CA2555050C (en) *	2004-02-18	2017-11-28	Boehringer Ingelheim International Gmbh	8-[3-amino-piperidin-1-yl]-xanthine derivatives, the production thereof and the use in the form of a dpp-iv inhibitor
DE102004009039A1 (de)	2004-02-23	2005-09-08	Boehringer Ingelheim Pharma Gmbh & Co. Kg	8-[3-Amino-piperidin-1-yl]-xanthine, deren Herstellung und Verwendung als Arzneimittel
US7393847B2 (en)	2004-03-13	2008-07-01	Boehringer Ingleheim International Gmbh	Imidazopyridazinediones, their preparation and their use as pharmaceutical compositions
US7439370B2 (en)	2004-05-10	2008-10-21	Boehringer Ingelheim International Gmbh	Imidazole derivatives, their preparation and their use as intermediates for the preparation of pharmaceutical compositions and pesticides
DE102004030502A1 (de)	2004-06-24	2006-01-12	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Neue Imidazole und Triazole, deren Herstellung und Verwendung als Arzneimittel
DE102004043944A1 (de)	2004-09-11	2006-03-30	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Neue 8-(3-Amino-piperidin-1-yl)-7-(but-2-inyl)-xanthine, deren Herstellung und deren Verwendung als Arzneimittel
DE102004044221A1 (de)	2004-09-14	2006-03-16	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Neue 3-Methyl-7-butinyl-xanthine, deren Herstellung und deren Verwendung als Arzneimittel
DE102004054054A1 (de)	2004-11-05	2006-05-11	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Verfahren zur Herstellung chiraler 8-(3-Amino-piperidin-1-yl)-xanthine
AU2012205240B2 (en) *	2004-11-05	2015-03-26	Boehringer Ingelheim International Gmbh	Method for producing chiral 8-(3-amino-piperidin-1-yl)-xanthines
DE102005035891A1 (de) *	2005-07-30	2007-02-08	Boehringer Ingelheim Pharma Gmbh & Co. Kg	8-(3-Amino-piperidin-1-yl)-xanthine, deren Herstellung und deren Verwendung als Arzneimittel
GB0526291D0 (en)	2005-12-23	2006-02-01	Prosidion Ltd	Therapeutic method
MX2008013130A (es)	2006-04-12	2008-11-19	Probiodrug Ag	Inhibidores de enzima.
PE20110235A1 (es)	2006-05-04	2011-04-14	Boehringer Ingelheim Int	Combinaciones farmaceuticas que comprenden linagliptina y metmorfina
EP1852108A1 (en)	2006-05-04	2007-11-07	Boehringer Ingelheim Pharma GmbH & Co.KG	DPP IV inhibitor formulations
MX2008014024A (es)	2006-05-04	2008-11-14	Boehringer Ingelheim Int	Formas poliformas.
EP2057160A1 (en) *	2006-08-08	2009-05-13	Boehringer Ingelheim International GmbH	Pyrrolo [3, 2 -d]pyrimidines as dpp-iv inhibitors for the treatment of diabetes mellitus
JP5379692B2 (ja)	2006-11-09	2013-12-25	プロビオドルグエージー	潰瘍、癌及び他の疾患の治療のためのグルタミニルシクラーゼの阻害薬としての３−ヒドロキシ−１，５−ジヒドロ−ピロール−２−オン誘導体
EP2091948B1 (en)	2006-11-30	2012-04-18	Probiodrug AG	Novel inhibitors of glutaminyl cyclase
US9656991B2 (en)	2007-04-18	2017-05-23	Probiodrug Ag	Inhibitors of glutaminyl cyclase
BRPI0701664A2 (pt) *	2007-05-28	2009-01-13	Fundacao Universidade Fed De Sco Carlos	4-quinolinonas e quinolinas, processo de preparaÇço, formulaÇÕes farmacÊuticas e uso das mesmas
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2005
- 2005-02-12 CA CA2555050A patent/CA2555050C/en not_active Expired - Lifetime
- 2005-02-12 ME MEP-2009-235A patent/ME01108B/me unknown
- 2005-02-12 DK DK05707354T patent/DK1758905T3/da active
- 2005-02-12 BR BRPI0507873A patent/BRPI0507873B8/pt not_active IP Right Cessation
- 2005-02-12 EA EA200601496A patent/EA010854B1/ru active IP Right Revival
- 2005-02-12 DE DE502005007196T patent/DE502005007196D1/de not_active Expired - Lifetime
- 2005-02-12 EA EA200801601A patent/EA200801601A1/ru unknown
- 2005-02-12 RS RSP-2009/0303A patent/RS50982B/sr unknown
- 2005-02-12 ES ES05707354T patent/ES2326666T3/es not_active Expired - Lifetime
- 2005-02-12 CN CN2011100842167A patent/CN102199151A/zh active Pending
- 2005-02-12 AU AU2005219508A patent/AU2005219508B2/en not_active Expired
- 2005-02-12 WO PCT/EP2005/001427 patent/WO2005085246A1/de not_active Ceased
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- 2005-02-12 EP EP09158875.6A patent/EP2119717B1/de not_active Expired - Lifetime
- 2005-02-15 UY UY28749A patent/UY28749A1/es not_active Application Discontinuation
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2006
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- 2006-09-18 KR KR1020067019124A patent/KR101207224B1/ko not_active Expired - Lifetime
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- 2009-07-23 CY CY20091100791T patent/CY1109284T1/el unknown
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- 2010-08-09 JP JP2010178510A patent/JP2011006437A/ja active Pending
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Also Published As

Publication number	Publication date
MY144322A (en)	2011-08-29
HK1103402A1 (en)	2007-12-21
EP2119717A1 (de)	2009-11-18
AR047614A1 (es)	2006-01-25
EA010854B1 (ru)	2008-12-30
CA2555050A1 (en)	2005-09-15
UY28749A1 (es)	2005-09-30
DK1758905T3 (da)	2009-08-24
NO20062688L (no)	2006-09-14
JP4733058B2 (ja)	2011-07-27
EP1758905B1 (de)	2009-04-29
BRPI0507873A (pt)	2007-07-24
RS50982B (sr)	2010-10-31
HRP20090346T1 (hr)	2009-08-31
PE20060210A1 (es)	2006-04-10
KR20070006780A (ko)	2007-01-11
ES2326666T3 (es)	2009-10-16
AU2005219508A1 (en)	2005-09-15
EP1758905A1 (de)	2007-03-07
NZ548901A (en)	2010-08-27
JP2007522251A (ja)	2007-08-09
EA200801601A1 (ru)	2009-08-28
TW200538131A (en)	2005-12-01
CY1109284T1 (el)	2014-07-02
ME01108B (me)	2013-03-20
DE502005007196D1 (de)	2009-06-10
JP2011006437A (ja)	2011-01-13
IL176920A0 (en)	2006-12-10
CA2555050C (en)	2017-11-28
EP2119717B1 (de)	2018-01-17
WO2005085246A1 (de)	2005-09-15
ECSP066775A (es)	2006-11-16
AU2005219508B2 (en)	2012-02-16
KR101207224B1 (ko)	2012-12-03
IL176920A (en)	2012-03-29
CN102199151A (zh)	2011-09-28
IL217268A0 (en)	2012-02-29
EA200601496A1 (ru)	2007-02-27
SI1758905T1 (sl)	2009-10-31
PT1758905E (pt)	2009-07-16
TWI350756B (en)	2011-10-21
ATE430150T1 (de)	2009-05-15
BRPI0507873B8 (pt)	2021-05-25
BRPI0507873B1 (pt)	2018-09-25

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