PL2384327T3 - Związki ze skondensowanym pierścieniem i ich zastosowanie - Google Patents

Związki ze skondensowanym pierścieniem i ich zastosowanie

Info

Publication number
PL2384327T3
PL2384327T3 PL10703532T PL10703532T PL2384327T3 PL 2384327 T3 PL2384327 T3 PL 2384327T3 PL 10703532 T PL10703532 T PL 10703532T PL 10703532 T PL10703532 T PL 10703532T PL 2384327 T3 PL2384327 T3 PL 2384327T3
Authority
PL
Poland
Prior art keywords
fused ring
ring compound
compound
fused
ring
Prior art date
Application number
PL10703532T
Other languages
English (en)
Inventor
Tsuyoshi Maekawa
Hideyuki Igawa
Original Assignee
Takeda Pharmaceuticals Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Pharmaceuticals Co filed Critical Takeda Pharmaceuticals Co
Publication of PL2384327T3 publication Critical patent/PL2384327T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Cardiology (AREA)
  • Obesity (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Endocrinology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Child & Adolescent Psychology (AREA)
  • Vascular Medicine (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
PL10703532T 2009-01-30 2010-01-29 Związki ze skondensowanym pierścieniem i ich zastosowanie PL2384327T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2009020720 2009-01-30
PCT/JP2010/051651 WO2010087515A1 (en) 2009-01-30 2010-01-29 Fused ring compound and use thereof
EP10703532.1A EP2384327B1 (en) 2009-01-30 2010-01-29 Fused ring compound and use thereof

Publications (1)

Publication Number Publication Date
PL2384327T3 true PL2384327T3 (pl) 2013-12-31

Family

ID=42026435

Family Applications (1)

Application Number Title Priority Date Filing Date
PL10703532T PL2384327T3 (pl) 2009-01-30 2010-01-29 Związki ze skondensowanym pierścieniem i ich zastosowanie

Country Status (36)

Country Link
US (4) US8283353B2 (pl)
EP (1) EP2384327B1 (pl)
JP (2) JP4892649B1 (pl)
KR (1) KR20110113758A (pl)
CN (2) CN102369205B (pl)
AR (1) AR075344A1 (pl)
AU (1) AU2010208863A1 (pl)
CA (1) CA2750710C (pl)
CL (1) CL2011001848A1 (pl)
CO (1) CO6362011A2 (pl)
CR (1) CR20110463A (pl)
CY (1) CY1114530T1 (pl)
DK (1) DK2384327T3 (pl)
DO (1) DOP2011000249A (pl)
EA (1) EA019823B1 (pl)
EC (1) ECSP11011294A (pl)
ES (1) ES2433225T3 (pl)
GE (1) GEP20135961B (pl)
HR (1) HRP20131017T1 (pl)
IL (1) IL214283A0 (pl)
MA (1) MA33071B1 (pl)
ME (1) ME01621B (pl)
MX (1) MX2011008058A (pl)
MY (1) MY152946A (pl)
NZ (1) NZ594606A (pl)
PE (1) PE20120593A1 (pl)
PL (1) PL2384327T3 (pl)
PT (1) PT2384327E (pl)
RS (1) RS53012B (pl)
SG (1) SG173135A1 (pl)
SI (1) SI2384327T1 (pl)
TN (1) TN2011000368A1 (pl)
TW (2) TWI468410B (pl)
UY (1) UY32409A (pl)
WO (1) WO2010087515A1 (pl)
ZA (1) ZA201105867B (pl)

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CA2750710C (en) 2009-01-30 2018-09-04 Takeda Pharmaceutical Company Limited Fused ring compound and use thereof
SI2655375T1 (sl) 2010-12-23 2015-03-31 Sanofi Derivati pirimidinona, njihova priprava in njihova farmacevtska uporaba
CZ304252B6 (cs) * 2011-04-11 2014-01-29 Zentiva, K. S. Způsob výroby 2-ethoxy-1-((2´-(5-oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl)bifenyl-4-yl)methyl)-1H-benzo[d]imidazol-7-karboxylátů a jejich převedení na azilsartan
MX388824B (es) 2016-06-20 2025-03-20 Novartis Ag Formas cristalinas de compuesto de triazolopirimidina.
KR102437623B1 (ko) 2017-09-26 2022-08-26 에코랍 유에스에이 인코퍼레이티드 산/음이온성 항균 및 살바이러스 조성물 및 이의 용도
SG11202011881PA (en) 2018-05-31 2020-12-30 Hua Medicine Shanghai Ltd Pharmaceutical combination, composition and combination formulation comprising glucokinase activator and dpp-iv inhibitor, and preparation method and use thereof
US11066404B2 (en) 2018-10-11 2021-07-20 Incyte Corporation Dihydropyrido[2,3-d]pyrimidinone compounds as CDK2 inhibitors
US11384083B2 (en) 2019-02-15 2022-07-12 Incyte Corporation Substituted spiro[cyclopropane-1,5′-pyrrolo[2,3-d]pyrimidin]-6′(7′h)-ones as CDK2 inhibitors
WO2020180959A1 (en) 2019-03-05 2020-09-10 Incyte Corporation Pyrazolyl pyrimidinylamine compounds as cdk2 inhibitors
US11919904B2 (en) 2019-03-29 2024-03-05 Incyte Corporation Sulfonylamide compounds as CDK2 inhibitors
US11440914B2 (en) 2019-05-01 2022-09-13 Incyte Corporation Tricyclic amine compounds as CDK2 inhibitors
US11447494B2 (en) 2019-05-01 2022-09-20 Incyte Corporation Tricyclic amine compounds as CDK2 inhibitors
MX2022001940A (es) 2019-08-14 2022-05-10 Incyte Corp Compuestos de imidazolil pirimidinilamina como inhibidores de cdk2.
CN115298177B (zh) 2019-10-11 2025-01-17 因赛特公司 作为cdk2抑制剂的双环胺
CN112745319B (zh) * 2019-10-30 2022-06-17 中国科学院上海药物研究所 一类取代三环结构的化合物、其制备方法及用途
EP4075976A1 (en) 2019-12-16 2022-10-26 Ecolab USA Inc. Anionic surfactant impact on virucidal efficacy
US11981671B2 (en) 2021-06-21 2024-05-14 Incyte Corporation Bicyclic pyrazolyl amines as CDK2 inhibitors
US11976073B2 (en) 2021-12-10 2024-05-07 Incyte Corporation Bicyclic amines as CDK2 inhibitors

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FR2672892B1 (fr) * 1991-02-20 1994-01-14 Synthelabo Derives de 4-pyrimidinones, leur preparation et leur application en therapeutique.
IL102183A (en) * 1991-06-27 1999-11-30 Takeda Chemical Industries Ltd Biphenyl substituted heterocyclic compounds their production and pharmaceutical compositions comprising them
TW251288B (pl) * 1991-06-27 1995-07-11 Takeda Dharm Industry Co Ltd
IT1250749B (it) 1991-08-02 1995-04-21 Luso Farmaco Inst Composti eterociclici ad attivita' a ii antagonista
FR2687677B1 (fr) * 1992-02-24 1996-10-11 Union Pharma Scient Appl Nouveaux derives de polyazaindenes antagonistes des recepteurs a l'angiotensine ii ; leurs procedes de preparation, compositions pharmaceutiques les contenant.
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EP2253630A1 (en) * 2007-05-21 2010-11-24 Takeda Pharmaceutical Company Limited Heterocyclic compound and use thereof
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CA2750710C (en) 2009-01-30 2018-09-04 Takeda Pharmaceutical Company Limited Fused ring compound and use thereof

Also Published As

Publication number Publication date
CA2750710C (en) 2018-09-04
US20100197683A1 (en) 2010-08-05
US20110294832A1 (en) 2011-12-01
JP2011251970A (ja) 2011-12-15
US20140046056A1 (en) 2014-02-13
DK2384327T3 (da) 2013-10-28
DOP2011000249A (es) 2011-09-15
MX2011008058A (es) 2011-09-01
TN2011000368A1 (en) 2013-03-27
EA019823B1 (ru) 2014-06-30
AR075344A1 (es) 2011-03-23
EP2384327A1 (en) 2011-11-09
EP2384327B1 (en) 2013-07-31
CO6362011A2 (es) 2012-01-20
TW201031669A (en) 2010-09-01
US20110288087A1 (en) 2011-11-24
GEP20135961B (en) 2013-11-11
CN102369205A (zh) 2012-03-07
ZA201105867B (en) 2012-10-31
ES2433225T3 (es) 2013-12-10
TW201444848A (zh) 2014-12-01
SG173135A1 (en) 2011-08-29
MA33071B1 (fr) 2012-02-01
ME01621B (me) 2014-09-20
RS53012B (sr) 2014-04-30
CY1114530T1 (el) 2017-01-25
EA201101138A1 (ru) 2012-04-30
CL2011001848A1 (es) 2012-02-03
SI2384327T1 (sl) 2013-12-31
CA2750710A1 (en) 2010-08-05
KR20110113758A (ko) 2011-10-18
WO2010087515A1 (en) 2010-08-05
HK1162505A1 (en) 2012-08-31
JP2012513952A (ja) 2012-06-21
JP5676379B2 (ja) 2015-02-25
NZ594606A (en) 2013-06-28
US8921379B2 (en) 2014-12-30
PE20120593A1 (es) 2012-05-21
MY152946A (en) 2014-12-15
CN103788097B (zh) 2016-03-30
HRP20131017T1 (hr) 2013-12-06
US8592431B2 (en) 2013-11-26
US8283353B2 (en) 2012-10-09
JP4892649B1 (ja) 2012-03-07
CN102369205B (zh) 2014-10-29
TWI468410B (zh) 2015-01-11
PT2384327E (pt) 2013-11-07
US9115136B2 (en) 2015-08-25
CR20110463A (es) 2011-12-01
ECSP11011294A (es) 2011-09-30
CN103788097A (zh) 2014-05-14
UY32409A (es) 2010-08-31
AU2010208863A1 (en) 2011-09-08
IL214283A0 (en) 2011-09-27

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