PL2717893T3 - Kompozycje nanocząstek lipidowych i sposoby do dostarczania mRNA - Google Patents

Kompozycje nanocząstek lipidowych i sposoby do dostarczania mRNA

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Publication number
PL2717893T3
PL2717893T3 PL12728007T PL12728007T PL2717893T3 PL 2717893 T3 PL2717893 T3 PL 2717893T3 PL 12728007 T PL12728007 T PL 12728007T PL 12728007 T PL12728007 T PL 12728007T PL 2717893 T3 PL2717893 T3 PL 2717893T3
Authority
PL
Poland
Prior art keywords
methods
lipid nanoparticle
nanoparticle compositions
mrna delivery
mrna
Prior art date
Application number
PL12728007T
Other languages
English (en)
Inventor
Braydon Charles Guild
Frank Derosa
Michael Heartlein
Original Assignee
Translate Bio, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=46317537&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL2717893(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Translate Bio, Inc. filed Critical Translate Bio, Inc.
Publication of PL2717893T3 publication Critical patent/PL2717893T3/pl

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A61K48/0008—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'non-active' part of the composition delivered, e.g. wherein such 'non-active' part is not delivered simultaneously with the 'active' part of the composition
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A61K31/713—Double-stranded nucleic acids or oligonucleotides
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    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/47—Hydrolases (3) acting on glycosyl compounds (3.2), e.g. cellulases, lactases
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    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
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    • A61K38/4846—Factor VII (3.4.21.21); Factor IX (3.4.21.22); Factor Xa (3.4.21.6); Factor XI (3.4.21.27); Factor XII (3.4.21.38)
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    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/505—Erythropoietin [EPO]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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    • C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
    • C07K14/8121—Serpins
    • C07K14/8125—Alpha-1-antitrypsin
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    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/88—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation using microencapsulation, e.g. using amphiphile liposome vesicle
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    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2465—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1) acting on alpha-galactose-glycoside bonds, e.g. alpha-galactosidase (3.2.1.22)
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    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/644—Coagulation factor IXa (3.4.21.22)
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    • C12Y—ENZYMES
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    • C12Y302/01022—Alpha-galactosidase (3.2.1.22)
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    • C12Y—ENZYMES
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PL12728007T 2011-06-08 2012-06-08 Kompozycje nanocząstek lipidowych i sposoby do dostarczania mRNA PL2717893T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161494881P 2011-06-08 2011-06-08
PCT/US2012/041724 WO2012170930A1 (en) 2011-06-08 2012-06-08 Lipid nanoparticle compositions and methods for mrna delivery
EP12728007.1A EP2717893B1 (en) 2011-06-08 2012-06-08 Lipid nanoparticle compositions and methods for mrna delivery

Publications (1)

Publication Number Publication Date
PL2717893T3 true PL2717893T3 (pl) 2019-12-31

Family

ID=46317537

Family Applications (2)

Application Number Title Priority Date Filing Date
PL12728007T PL2717893T3 (pl) 2011-06-08 2012-06-08 Kompozycje nanocząstek lipidowych i sposoby do dostarczania mRNA
PL19172992T PL3586861T3 (pl) 2011-06-08 2012-06-08 Kompozycje nanocząstek lipidowych i sposoby dostarczania mrna

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PL19172992T PL3586861T3 (pl) 2011-06-08 2012-06-08 Kompozycje nanocząstek lipidowych i sposoby dostarczania mrna

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US (24) US20140206753A1 (pl)
EP (4) EP3586861B1 (pl)
JP (7) JP6184945B2 (pl)
KR (4) KR20200084048A (pl)
CN (3) CN111671918A (pl)
AU (5) AU2012267531B2 (pl)
BR (1) BR112013031553A2 (pl)
CA (2) CA3107288A1 (pl)
CL (1) CL2013003478A1 (pl)
CY (1) CY1122123T1 (pl)
DK (3) DK3586861T3 (pl)
ES (3) ES2740248T3 (pl)
HK (1) HK1199206A1 (pl)
HR (1) HRP20191338T1 (pl)
HU (1) HUE044277T2 (pl)
IL (3) IL280771B2 (pl)
LT (1) LT2717893T (pl)
ME (1) ME03491B (pl)
MX (2) MX367605B (pl)
NZ (1) NZ719345A (pl)
PE (1) PE20140797A1 (pl)
PL (2) PL2717893T3 (pl)
PT (2) PT2717893T (pl)
RS (1) RS59037B1 (pl)
RU (1) RU2013154295A (pl)
SI (1) SI2717893T1 (pl)
SM (1) SMT201900445T1 (pl)
TR (1) TR201910686T4 (pl)
WO (1) WO2012170930A1 (pl)

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EP3269395A1 (en) 2008-11-07 2018-01-17 Massachusetts Institute Of Technology Aminoalcohol lipidoids and uses thereof
EP3318248B1 (en) 2009-12-01 2019-04-10 Translate Bio, Inc. Delivery of mrna for the augmentation of proteins and enzymes in human genetic diseases
WO2012019168A2 (en) 2010-08-06 2012-02-09 Moderna Therapeutics, Inc. Engineered nucleic acids and methods of use thereof
US9193827B2 (en) 2010-08-26 2015-11-24 Massachusetts Institute Of Technology Poly(beta-amino alcohols), their preparation, and uses thereof
EP2625189B1 (en) 2010-10-01 2018-06-27 ModernaTX, Inc. Engineered nucleic acids and methods of use thereof
US8853377B2 (en) 2010-11-30 2014-10-07 Shire Human Genetic Therapies, Inc. mRNA for use in treatment of human genetic diseases
EP2691443B1 (en) 2011-03-28 2021-02-17 Massachusetts Institute of Technology Conjugated lipomers and uses thereof
AU2012236099A1 (en) 2011-03-31 2013-10-03 Moderna Therapeutics, Inc. Delivery and formulation of engineered nucleic acids
US20140199233A1 (en) * 2011-05-11 2014-07-17 The Regents Of The University Of California Enhanced Growth Inhibition of Osteosarcoma by Cytotoxic Polymerized Liposomal Nanoparticles Targeting the Alcam Cell Surface Receptor
ES2795110T3 (es) 2011-06-08 2020-11-20 Translate Bio Inc Lípidos escindibles
RU2013154295A (ru) 2011-06-08 2015-07-20 Шир Хьюман Дженетик Терапис, Инк. КОМПОЗИЦИИ ЛИПИДНЫХ НАНОЧАСТИЦ И СПОСОБЫ ДЛЯ ДОСТАВКИ мРНК
EP2729165B1 (en) 2011-07-06 2017-11-08 GlaxoSmithKline Biologicals SA Immunogenic combination compositions and uses thereof
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