PL2753622T3 - Wytwarzanie alkaloidów bez oddzielania związków pośrednich - Google Patents

Wytwarzanie alkaloidów bez oddzielania związków pośrednich

Info

Publication number
PL2753622T3
PL2753622T3 PL12769528T PL12769528T PL2753622T3 PL 2753622 T3 PL2753622 T3 PL 2753622T3 PL 12769528 T PL12769528 T PL 12769528T PL 12769528 T PL12769528 T PL 12769528T PL 2753622 T3 PL2753622 T3 PL 2753622T3
Authority
PL
Poland
Prior art keywords
alkaloids
intermediates
isolation
production
Prior art date
Application number
PL12769528T
Other languages
English (en)
Inventor
Peter X Wang
Tao Jiang
David W Berberich
Original Assignee
SpecGx LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SpecGx LLC filed Critical SpecGx LLC
Publication of PL2753622T3 publication Critical patent/PL2753622T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
    • C07D489/02—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with oxygen atoms attached in positions 3 and 6, e.g. morphine, morphinone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32—Alcohol-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/36—Opioid-abuse
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/22—Bridged ring systems
    • C07D221/28—Morphinans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
    • C07D489/02—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with oxygen atoms attached in positions 3 and 6, e.g. morphine, morphinone
    • C07D489/04—Salts; Organic complexes

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Addiction (AREA)
  • Neurosurgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
PL12769528T 2011-09-08 2012-09-07 Wytwarzanie alkaloidów bez oddzielania związków pośrednich PL2753622T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161532253P 2011-09-08 2011-09-08
PCT/US2012/054099 WO2013036729A1 (en) 2011-09-08 2012-09-07 Production of alkaloids without the isolation of intermediates
EP12769528.6A EP2753622B1 (en) 2011-09-08 2012-09-07 Production of alkaloids without the isolation of intermediates

Publications (1)

Publication Number Publication Date
PL2753622T3 true PL2753622T3 (pl) 2016-07-29

Family

ID=46982922

Family Applications (1)

Application Number Title Priority Date Filing Date
PL12769528T PL2753622T3 (pl) 2011-09-08 2012-09-07 Wytwarzanie alkaloidów bez oddzielania związków pośrednich

Country Status (14)

Country Link
US (1) US8624031B2 (pl)
EP (1) EP2753622B1 (pl)
JP (1) JP2014526467A (pl)
KR (1) KR20140063763A (pl)
CN (1) CN103917543A (pl)
AU (1) AU2012304484B2 (pl)
BR (1) BR112014005421A2 (pl)
CA (1) CA2845187A1 (pl)
ES (1) ES2566620T3 (pl)
IL (1) IL231292A0 (pl)
MX (1) MX2014002630A (pl)
PL (1) PL2753622T3 (pl)
RU (1) RU2014112493A (pl)
WO (1) WO2013036729A1 (pl)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2913558C (en) * 2013-05-24 2021-06-29 Rhodes Technologies Opioid ketal compounds and uses thereof

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Also Published As

Publication number Publication date
CA2845187A1 (en) 2013-03-14
EP2753622A1 (en) 2014-07-16
US20130066080A1 (en) 2013-03-14
CN103917543A (zh) 2014-07-09
AU2012304484B2 (en) 2016-07-28
BR112014005421A2 (pt) 2017-04-04
WO2013036729A1 (en) 2013-03-14
EP2753622B1 (en) 2016-01-20
US8624031B2 (en) 2014-01-07
IL231292A0 (en) 2014-04-30
KR20140063763A (ko) 2014-05-27
RU2014112493A (ru) 2015-10-20
ES2566620T3 (es) 2016-04-14
MX2014002630A (es) 2014-04-14
AU2012304484A1 (en) 2014-02-27
JP2014526467A (ja) 2014-10-06

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