PL2848258T3 - Leczenie rodzinnej gorączki śródziemnomorskiej przeciwciałami przeciwko IL-1beta - Google Patents

Leczenie rodzinnej gorączki śródziemnomorskiej przeciwciałami przeciwko IL-1beta

Info

Publication number: PL2848258T3
Authority: PL; Poland
Prior art keywords: treatment; mediterranean fever; familial mediterranean; 1beta antibodies; 1beta
Prior art date: 2005-10-26

Application number

PL14191582T

Other languages

English (en)

Inventor

Phil Lowe

Hermann Gram

Thomas Jung

Timothy Wright

Trevor Mundel

Original Assignee

Novartis Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2005-10-26

Filing date

2006-10-24

Publication date

2018-06-29

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=37806690&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL2848258(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2006-10-24 Application filed by Novartis Ag filed Critical Novartis Ag

2018-06-29 Publication of PL2848258T3 publication Critical patent/PL2848258T3/pl

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/244—Interleukins [IL]
- C07K16/245—IL-1
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/20—Interleukins [IL]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/244—Interleukins [IL]
- C07K16/246—IL-2
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Immunology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Epidemiology (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Physical Education & Sports Medicine (AREA)
Neurology (AREA)
Endocrinology (AREA)
Mycology (AREA)
Microbiology (AREA)
Gastroenterology & Hepatology (AREA)
Rheumatology (AREA)
Orthopedic Medicine & Surgery (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Transplantation (AREA)
Zoology (AREA)
Pulmonology (AREA)
Hospice & Palliative Care (AREA)
Pain & Pain Management (AREA)
Vascular Medicine (AREA)

PL14191582T 2005-10-26 2006-10-24 Leczenie rodzinnej gorączki śródziemnomorskiej przeciwciałami przeciwko IL-1beta PL2848258T3 (pl)

Applications Claiming Priority (5)

Application Number	Priority Date	Filing Date	Title
US73043505P	2005-10-26	2005-10-26
US74212505P	2005-12-02	2005-12-02
EP06826560A EP1940465B1 (en)	2005-10-26	2006-10-24	Novel use of anti il-1beta antibodies
EP14191582.7A EP2848258B1 (en)	2005-10-26	2006-10-24	Treatment of familial Mediterranean Fever with anti IL-1beta antibodies
EP10181100A EP2332577A1 (en)	2005-10-26	2006-10-24	Novel use of IL-1beta compounds

Publications (1)

Publication Number	Publication Date
PL2848258T3 true PL2848258T3 (pl)	2018-06-29

Family

ID=37806690

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
PL14191582T PL2848258T3 (pl)	2005-10-26	2006-10-24	Leczenie rodzinnej gorączki śródziemnomorskiej przeciwciałami przeciwko IL-1beta
PL06826560T PL1940465T3 (pl)	2005-10-26	2006-10-24	Nowe zastosowanie przeciwciał anty-IL-1beta

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
PL06826560T PL1940465T3 (pl)	2005-10-26	2006-10-24	Nowe zastosowanie przeciwciał anty-IL-1beta

Country Status (28)

Country	Link
US (9)	US8105587B2 (pl)
EP (5)	EP2848258B1 (pl)
JP (4)	JP2009513645A (pl)
KR (3)	KR101749388B1 (pl)
CN (2)	CN102861332A (pl)
AU (1)	AU2006306280B2 (pl)
BR (1)	BRPI0617830B8 (pl)
CA (3)	CA2963828A1 (pl)
CY (4)	CY1113378T1 (pl)
DK (2)	DK2848258T3 (pl)
ES (3)	ES2944067T3 (pl)
HU (2)	HUE036973T2 (pl)
IL (4)	IL190545A (pl)
JO (2)	JO2826B1 (pl)
LT (3)	LT2848258T (pl)
LU (2)	LU92326I2 (pl)
MA (1)	MA29919B1 (pl)
NO (2)	NO345888B1 (pl)
NZ (1)	NZ567222A (pl)
PH (2)	PH12013501287B1 (pl)
PL (2)	PL2848258T3 (pl)
PT (2)	PT2848258T (pl)
RU (2)	RU2468817C2 (pl)
SI (2)	SI2848258T1 (pl)
TN (1)	TNSN08189A1 (pl)
TR (1)	TR201802449T4 (pl)
TW (3)	TWI388335B (pl)
WO (1)	WO2007050607A2 (pl)

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WO2008145664A1 (en) *	2007-05-29	2008-12-04	Novartis Ag	New indications for anti- il-i-beta therapy
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UY37758A (es)	2017-06-12	2019-01-31	Novartis Ag	Método de fabricación de anticuerpos biespecíficos, anticuerpos biespecíficos y uso terapéutico de dichos anticuerpos
WO2018234879A1 (en)	2017-06-22	2018-12-27	Novartis Ag	USE OF IL-1β BINDING ANTIBODIES IN THE TREATMENT OF CANCER
JP2021523894A (ja)	2018-05-09	2021-09-09	ノバルティスアーゲー	カナキヌマブの使用
US20220056123A1 (en)	2018-12-21	2022-02-24	Novartis Ag	Use of il-1beta binding antibodies
US20220025036A1 (en)	2018-12-21	2022-01-27	Novartis Ag	Use of il-1beta binding antibodies
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JP2022516850A (ja)	2018-12-21	2022-03-03	ノバルティスアーゲー	骨髄異形成症候群の治療又は予防におけるＩＬ－１β抗体の使用
TWI793503B (zh)	2020-01-20	2023-02-21	美商美國禮來大藥廠	抗IL-1β抗體
KR20230109107A (ko) *	2022-01-10	2023-07-19	(주)지아이이노베이션	글루카곤-유사 펩타이드-1 및 인터루킨-1 수용체 길항제를 포함하는 퇴행성 뇌질환 예방 또는 치료용 약학 조성물

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CA2963828A1 (en)	2005-10-26	2007-05-03	Novartis Ag	Novel use of il-1beta compounds

2006
- 2006-10-24 CA CA2963828A patent/CA2963828A1/en not_active Abandoned
- 2006-10-24 NZ NZ567222A patent/NZ567222A/en not_active IP Right Cessation
- 2006-10-24 KR KR1020147035512A patent/KR101749388B1/ko active Active
- 2006-10-24 DK DK14191582.7T patent/DK2848258T3/en active
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Also Published As

Publication number	Publication date
EP2848258A1 (en)	2015-03-18
PH12013501287A1 (en)	2016-02-01
IL245387B (en)	2019-09-26
PH12020500559A1 (en)	2021-06-14
LT2848258T (lt)	2018-02-26
KR101518064B1 (ko)	2015-05-06
ES2389110T3 (es)	2012-10-23
HK1121041A1 (en)	2009-04-17
CN101291693B (zh)	2012-10-03
IL258983B (en)	2020-10-29
IL245387A0 (en)	2016-06-30
JO2826B1 (en)	2014-09-15
MA29919B1 (fr)	2008-11-03
JP2017206552A (ja)	2017-11-24
CA2626214A1 (en)	2007-05-03
RU2008120625A (ru)	2010-01-20
US20260125463A1 (en)	2026-05-07
EP1940465A2 (en)	2008-07-09
PT2848258T (pt)	2018-03-20
SI2848258T1 (en)	2018-03-30
TNSN08189A1 (en)	2009-10-30
AU2006306280B2 (en)	2010-06-17
IL190545A0 (en)	2008-11-03
NO345140B1 (no)	2020-10-12
US9649377B2 (en)	2017-05-16
LTPA2018506I1 (lt)	2018-06-25
ES2662420T3 (es)	2018-04-06
LTC2848258I2 (lt)	2019-08-12
CY2018018I2 (el)	2018-12-12
JP6286403B2 (ja)	2018-02-28
US20170218063A1 (en)	2017-08-03
JP6061747B2 (ja)	2017-01-18
EP3332807B1 (en)	2023-02-22
CA2898369C (en)	2017-06-20
IL258983A (en)	2018-06-28
US20120039910A1 (en)	2012-02-16
US8409576B2 (en)	2013-04-02
CY2018018I1 (el)	2018-12-12
LU92326I2 (fr)	2014-02-05
TR201802449T4 (tr)	2018-03-21
US8105587B2 (en)	2012-01-31
CN102861332A (zh)	2013-01-09
PT1940465E (pt)	2012-10-03
BRPI0617830A2 (pt)	2011-08-09
JOP20140120B1 (ar)	2021-08-17
EP3332807A3 (en)	2018-06-20
IL190545A (en)	2016-09-29
JP2013166757A (ja)	2013-08-29
AU2006306280A1 (en)	2007-05-03
HUS1800025I1 (hu)	2018-07-30
CA2898369A1 (en)	2007-05-03
DK2848258T3 (en)	2018-03-19
RU2012133522A (ru)	2014-02-20
KR20170038131A (ko)	2017-04-05
US20240083997A1 (en)	2024-03-14
TWI388335B (zh)	2013-03-11
PH12013501287B1 (en)	2016-02-01
CY1113378T1 (el)	2015-11-04
NO20200810A1 (no)	2008-07-22
LU92326I9 (pl)	2019-01-16
BRPI0617830B8 (pt)	2021-05-25
US20180201674A1 (en)	2018-07-19
CN101291693A (zh)	2008-10-22
LUC00078I2 (fr)	2018-08-14
NZ567222A (en)	2011-07-29
TW200803898A (en)	2008-01-16
CY2013046I1 (el)	2015-11-04
KR20150013834A (ko)	2015-02-05
CA2626214C (en)	2016-06-21
WO2007050607A3 (en)	2007-06-28
EP2848258B1 (en)	2017-12-13
US20130171167A1 (en)	2013-07-04
IL277406A (en)	2020-11-30
WO2007050607A2 (en)	2007-05-03
DK1940465T3 (da)	2012-10-22
ES2944067T3 (es)	2023-06-19
KR101749388B1 (ko)	2017-06-20
JP2009513645A (ja)	2009-04-02
SI1940465T1 (sl)	2012-10-30
NO345888B1 (no)	2021-09-27
EP4218815A2 (en)	2023-08-02
HK1204767A1 (en)	2015-12-04
US20080286266A1 (en)	2008-11-20
CY2013046I2 (el)	2015-11-04
TW201617097A (zh)	2016-05-16
TW201302220A (zh)	2013-01-16
EP4218815A3 (en)	2024-03-27
EP2332577A1 (en)	2011-06-15
US20210147533A1 (en)	2021-05-20
RU2571563C2 (ru)	2015-12-20
CA2963828A1 (en)	2007-05-03
KR20080059598A (ko)	2008-06-30
NO20082344L (no)	2008-07-22
HUE036973T2 (hu)	2018-08-28
HK1252316A1 (en)	2019-05-24
BRPI0617830B1 (pt)	2020-10-20
CY1120018T1 (el)	2018-12-12
EP1940465B1 (en)	2012-08-01
TWI626056B (zh)	2018-06-11
LTC1940465I2 (lt)	2017-12-11
RU2468817C2 (ru)	2012-12-10
TWI537003B (zh)	2016-06-11
US20150322148A1 (en)	2015-11-12
JP2016020377A (ja)	2016-02-04
PL1940465T3 (pl)	2013-01-31
EP3332807A2 (en)	2018-06-13

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