PL318766A1 - Derivatives of benzoxazoles and pyridines useful in treating diabetes of type ii - Google Patents

Derivatives of benzoxazoles and pyridines useful in treating diabetes of type ii

Info

Publication number
PL318766A1
PL318766A1 PL95318766A PL31876695A PL318766A1 PL 318766 A1 PL318766 A1 PL 318766A1 PL 95318766 A PL95318766 A PL 95318766A PL 31876695 A PL31876695 A PL 31876695A PL 318766 A1 PL318766 A1 PL 318766A1
Authority
PL
Poland
Prior art keywords
benzoxazoles
derivatives
type
treating diabetes
pyridines useful
Prior art date
Application number
PL95318766A
Other languages
English (en)
Inventor
David Haigh
Harshad Kantilal Rami
Original Assignee
Smithkline Beecham Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB9415330A external-priority patent/GB9415330D0/en
Priority claimed from GBGB9425599.9A external-priority patent/GB9425599D0/en
Priority claimed from GBGB9509923.0A external-priority patent/GB9509923D0/en
Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc
Publication of PL318766A1 publication Critical patent/PL318766A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
    • C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
    • C07D263/58—Benzoxazoles; Hydrogenated benzoxazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
PL95318766A 1994-07-29 1995-07-28 Derivatives of benzoxazoles and pyridines useful in treating diabetes of type ii PL318766A1 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB9415330A GB9415330D0 (en) 1994-07-29 1994-07-29 Novel compounds
GBGB9425599.9A GB9425599D0 (en) 1994-12-19 1994-12-19 Novel compounds
GBGB9509923.0A GB9509923D0 (en) 1995-05-17 1995-05-17 Novel compounds
PCT/GB1995/001323 WO1996004261A1 (en) 1994-07-29 1995-06-07 Benzoxazoles and pryridine derivatives useful in the treatment of the type ii diabetes

Publications (1)

Publication Number Publication Date
PL318766A1 true PL318766A1 (en) 1997-07-07

Family

ID=27267309

Family Applications (1)

Application Number Title Priority Date Filing Date
PL95318766A PL318766A1 (en) 1994-07-29 1995-07-28 Derivatives of benzoxazoles and pyridines useful in treating diabetes of type ii

Country Status (16)

Country Link
EP (1) EP0772605A1 (pt)
AP (1) AP776A (pt)
BR (1) BR9508468A (pt)
CA (1) CA2196079A1 (pt)
CZ (1) CZ25497A3 (pt)
DZ (1) DZ1916A1 (pt)
FI (1) FI970357L (pt)
HU (1) HUT76637A (pt)
IL (3) IL114759A (pt)
MA (1) MA23632A1 (pt)
MX (1) MX9700763A (pt)
NO (1) NO307827B1 (pt)
OA (1) OA10470A (pt)
PL (1) PL318766A1 (pt)
SK (1) SK12297A3 (pt)
WO (2) WO1996004261A1 (pt)

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US6090839A (en) * 1996-12-23 2000-07-18 Merck & Co., Inc. Antidiabetic agents
US6160000A (en) * 1996-12-23 2000-12-12 Merck & Co., Inc. Antidiabetic agents based on aryl and heteroarylacetic acids
IL135177A0 (en) 1997-10-02 2001-05-20 Sankyo Co Amidocarboxylic acid derivatives and pharmaceutical compositions containing the same
US6440961B1 (en) 1997-10-27 2002-08-27 Dr. Reddy's Research Foundation Tricyclic compounds and their use in medicine: process for their preparation and pharmaceutical compositions containing them
US6265401B1 (en) * 1997-10-27 2001-07-24 Reddy-Cheminor, Inc. Bicyclic compounds and their use in medicine, process for their preparation and pharmaceutical compositions containing them
US6369067B1 (en) 1997-10-27 2002-04-09 Dr. Reddy's Research Foundation Monocyclic compounds and their use in medicine: process for their preparation and pharmaceutical compositions containing them
CN1280574A (zh) 1997-10-27 2001-01-17 雷迪研究基金会 新的杂环化合物及其在医药中的应用、它们的制备方法和含有它们的药物组合物
AU752059B2 (en) 1997-10-27 2002-09-05 Dr. Reddy's Laboratories Limited Bicyclic compounds, process for their preparation and pharmaceutical compositions containing them
US6444816B1 (en) 1997-10-27 2002-09-03 Dr. Reddy's Research Foundation Fused 7-oxo-pyrimidinyl compounds, preparation, composition and use thereof
AU749505B2 (en) * 1997-10-27 2002-06-27 Dr. Reddy's Laboratories Limited Novel tricyclic compounds and their use in medicine; process for their preparation and pharmaceutical compositions containing them
WO1999019313A1 (en) * 1997-10-27 1999-04-22 Dr. Reddy's Research Foundation Novel tricyclic compounds and their use in medicine; process for their preparation and pharmaceutical compositions containing them
JP2002507543A (ja) * 1998-05-27 2002-03-12 ドクター・レディーズ・リサーチ・ファウンデーション 二環系化合物、その製造方法およびそれらを含有する薬学的組成物
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US6365586B1 (en) 1998-10-21 2002-04-02 Novo Nordisk A/S Compounds, their preparation and use
US6468996B1 (en) 1998-10-21 2002-10-22 Novo Nordisk A/S Substituted hetero-polycyclic compounds as PPARα and PPARγ activators
US6248781B1 (en) 1998-10-21 2001-06-19 Novo Nordisk A/S Compounds useful in the treatment of conditions mediated by peroxisome proliferator-activated receptors (PPAR)
JP2002527503A (ja) * 1998-10-21 2002-08-27 ノボ ノルディスク アクティーゼルスカブ 新規化合物類、それらの調製及び使用
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US6300339B1 (en) 1998-10-21 2001-10-09 Novo Nordisk A/S Compounds, their preparation and use
AU6325599A (en) * 1998-10-21 2000-05-08 Dr. Reddy's Research Foundation New compounds, their preparation and use
WO2000023451A1 (en) * 1998-10-21 2000-04-27 Novo Nordisk A/S New compounds, their preparation and use
US6214820B1 (en) 1998-10-21 2001-04-10 Novo Nordisk A/S Compounds, their preparation and use
WO2000023416A1 (en) * 1998-10-21 2000-04-27 Novo Nordisk A/S New compounds, their preparation and use
US6531596B1 (en) 1998-10-29 2003-03-11 Dr. Reddy's Laboratories Ltd. Process for the preparation of new antidiabetic agents
AU763087B2 (en) * 1998-10-29 2003-07-10 Dr. Reddy's Laboratories Limited An improved process for the preparation of new antidiabetic agents
WO2000063189A1 (en) * 1999-04-16 2000-10-26 Novo Nordisk A/S Crystalline r- guanidines, arginine or (l) -arginine (2s) -2- ethoxy -3-{4- [2-(10h -phenoxazin -10-yl)ethoxy]phenyl}propanoate
US7414128B2 (en) 1999-04-20 2008-08-19 Dr. Reddy's Laboratories, Limited Crystalline R-guanidines, Arginine or (L)-Arginine (2S)-2-Ethoxy-3-{4-[2-(10H -phenoxazin-10-yl)ethoxy]phenyl}propanoate
KR20020005703A (ko) * 1999-04-20 2002-01-17 한센 핀 베네드, 안네 제헤르, 웨이콥 마리안느 신규한 화합물, 그의 제법 및 용도
US6274608B1 (en) 1999-04-20 2001-08-14 Novo Nordisk A/S Compounds, their preparation and use
US6972294B1 (en) 1999-04-20 2005-12-06 Novo Nordisk, A/S Compounds, their preparation and use
JP2002542246A (ja) 1999-04-20 2002-12-10 ノボ ノルディスク アクティーゼルスカブ 新規な化合物、それらの製造及び使用
US6369055B1 (en) 1999-04-20 2002-04-09 Novo Nordisk A/S Compounds, their preparation and use
WO2000063190A1 (en) * 1999-04-20 2000-10-26 Novo Nordisk A/S New compounds, their preparation and use
PL351987A1 (en) 1999-04-28 2003-07-14 Reddys Lab Ltd Dr Substitution bicyclic-heterocyclic compounds, method of obtaining thereof, and use of such compounds to control adiposis and to reduce the level of cholesterol
DE60005973T2 (de) 1999-08-27 2004-05-13 Eli Lilly And Co., Indianapolis Biaryl-oxa(thia)zolderivate und ihre verwendung als ppars modulatoren
ES2449194T3 (es) * 2000-01-19 2014-03-18 Cadila Healthcare Limited Compuestos que tienen actividades hipolipidémica e hipocolesterolémica, procedimiento para su preparación y composiciones farmacéuticas que los contienen
US6569901B2 (en) 2000-01-28 2003-05-27 Novo Nordisk A/S Alkynyl-substituted propionic acid derivatives, their preparation and use
US6555577B1 (en) 2000-01-28 2003-04-29 Novo Nordisk A/S Compounds, their preparation and use
BR0107902A (pt) * 2000-01-28 2002-11-05 Novo Nordisk As Composto, composição farmacêutica, métodos para o tratamento de doenças, e para o tratamento e/ou prevençao de, condições mediadas por receptores nucleares, e diabetes e/ou obesidade, uso de uim composto, processo para a preparação de um composto, e, método para tratar diabetes de tipo i, diabetes de tipo ii, tolerância prejudicada à glucose, resistência à insolina ou obesidade
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US7067530B2 (en) 2001-07-30 2006-06-27 Novo Nordisk A/S Compounds, their preparation and use
US7220877B2 (en) 2001-10-17 2007-05-22 Novo Nordisk A/S Compounds, their preparation and use
JP2005518408A (ja) 2001-12-29 2005-06-23 ノボ　ノルディスク　アクティーゼルスカブ 異常脂肪血症を治療するための、ｇｌｐ−１化合物と他の薬物との組み合わせ使用
US7015345B2 (en) 2002-02-21 2006-03-21 Asahi Kasei Pharma Corporation Propionic acid derivatives
US7816385B2 (en) 2002-12-20 2010-10-19 High Point Pharmaceuticals, Llc Dimeric dicarboxylic acid derivatives, their preparation and use
US6653334B1 (en) 2002-12-27 2003-11-25 Kowa Co., Ltd. Benzoxazole compound and pharmaceutical composition containing the same
US20100274022A1 (en) * 2007-04-26 2010-10-28 Pharmafrontier Co., Ltd. G protein-coupled receptor inhibitor and pharmaceutical product
EP3009136A1 (en) 2011-01-31 2016-04-20 Cadila Healthcare Limited Treatment for lipodystrophy
IN2013MU01468A (pt) 2013-04-22 2015-04-17 Cadila Healthcare Ltd
PH12015502667B1 (en) 2013-05-30 2023-10-18 Zydus Lifesciences Ltd A process for preparation of pyrroles having hypolipidemic hypocholesteremic activities
TW201636015A (zh) 2013-07-05 2016-10-16 卡地拉保健有限公司 協同性組成物
IN2013MU02470A (pt) 2013-07-25 2015-06-26 Cadila Healthcare Ltd
IN2013MU02905A (pt) 2013-09-06 2015-07-03 Cadila Healthcare Ltd
WO2017064635A2 (en) 2015-10-14 2017-04-20 Cadila Healthcare Limited Pyrrole compound, compositions and process for preparation thereof
BR112019011740A2 (pt) 2016-12-09 2019-10-29 Cadila Healthcare Limited composição farmacêutica e método para o tratamento de colangite biliar primária

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US5089514A (en) * 1990-06-14 1992-02-18 Pfizer Inc. 3-coxazolyl [phenyl, chromanyl or benzofuranyl]-2-hydroxypropionic acid derivatives and analogs as hypoglycemic agents
CA2139442A1 (en) * 1992-07-03 1994-01-20 David Haigh Heterocyclic compounds as pharmaceutical

Also Published As

Publication number Publication date
MA23632A1 (fr) 1996-04-01
FI970357A0 (fi) 1997-01-28
IL114759A (en) 1999-10-28
WO1996004260A1 (en) 1996-02-15
AP9700918A0 (en) 1997-01-31
BR9508468A (pt) 1997-11-25
FI970357A7 (fi) 1997-03-26
NO970373L (no) 1997-03-18
FI970357L (fi) 1997-03-26
NO970373D0 (no) 1997-01-28
MX9700763A (es) 1997-05-31
IL125525A0 (en) 1999-03-12
WO1996004261A1 (en) 1996-02-15
IL114759A0 (en) 1995-12-31
AP776A (en) 1999-10-28
OA10470A (en) 2002-04-08
HUT76637A (en) 1997-10-28
DZ1916A1 (fr) 2002-02-17
CA2196079A1 (en) 1996-02-15
NO307827B1 (no) 2000-06-05
IL125525A (en) 2000-02-29
EP0772605A1 (en) 1997-05-14
SK12297A3 (en) 1997-08-06
CZ25497A3 (en) 1997-09-17

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