PL3350195T3 - Sposób syntezy i oczyszczania nukleozydu i/lub nukleotydu, zmodyfikowany nukleozyd i/lub nukleotyd, cząsteczka DNA i biblioteka oligonukleotydów zawierające zmodyfikowany nukleozyd i/lub nukleotyd oraz zastosowanie biblioteki oligonukleotydów - Google Patents
Sposób syntezy i oczyszczania nukleozydu i/lub nukleotydu, zmodyfikowany nukleozyd i/lub nukleotyd, cząsteczka DNA i biblioteka oligonukleotydów zawierające zmodyfikowany nukleozyd i/lub nukleotyd oraz zastosowanie biblioteki oligonukleotydówInfo
- Publication number
- PL3350195T3 PL3350195T3 PL16846944T PL16846944T PL3350195T3 PL 3350195 T3 PL3350195 T3 PL 3350195T3 PL 16846944 T PL16846944 T PL 16846944T PL 16846944 T PL16846944 T PL 16846944T PL 3350195 T3 PL3350195 T3 PL 3350195T3
- Authority
- PL
- Poland
- Prior art keywords
- nucleotide
- nucleoside
- oligonucleotide library
- modified nucleoside
- purification
- Prior art date
Links
- 239000002777 nucleoside Substances 0.000 title 3
- 150000003833 nucleoside derivatives Chemical class 0.000 title 3
- 239000002773 nucleotide Substances 0.000 title 3
- 125000003729 nucleotide group Chemical group 0.000 title 3
- 108091034117 Oligonucleotide Proteins 0.000 title 2
- 108020004414 DNA Proteins 0.000 title 1
- 102000053602 DNA Human genes 0.000 title 1
- 230000015572 biosynthetic process Effects 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 238000000746 purification Methods 0.000 title 1
- 238000003786 synthesis reaction Methods 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B40/00—Libraries per se, e.g. arrays, mixtures
- C40B40/04—Libraries containing only organic compounds
- C40B40/06—Libraries containing nucleotides or polynucleotides, or derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
- C07H19/073—Pyrimidine radicals with 2-deoxyribosyl as the saccharide radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H1/00—Processes for the preparation of sugar derivatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H1/00—Processes for the preparation of sugar derivatives
- C07H1/06—Separation; Purification
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
- C07H19/10—Pyrimidine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
- C07H21/04—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1048—SELEX
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/115—Aptamers, i.e. nucleic acids binding a target molecule specifically and with high affinity without hybridising therewith ; Nucleic acids binding to non-nucleic acids, e.g. aptamers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/16—Aptamers
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Bioinformatics & Computational Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PL413941A PL239946B1 (pl) | 2015-09-17 | 2015-09-17 | Sposób syntezy i oczyszczania nukleotydu, zmodyfikowany nukleotyd, cząsteczka DNA i biblioteka oligonukleotydów zawierające zmodyfikowany nukleotyd oraz zastosowanie biblioteki oligonukleotydów |
| PCT/PL2016/050038 WO2017048147A1 (en) | 2015-09-17 | 2016-09-13 | The method of synthesis and purification of a nucleoside and/or a nucleotide, a modified nucleoside and/or nucleotide, a dna molecule and an oligonucleotide library comprising said modified nucleoside and/or nucleotide and the use of said oligonucleotide library |
| EP16846944.3A EP3350195B9 (en) | 2015-09-17 | 2016-09-13 | The method of synthesis and purification of a nucleoside and/or a nucleotide, a modified nucleoside and/or nucleotide, a dna molecule and an oligonucleotide library comprising said modified nucleoside and/or nucleotide and the use of said oligonucleotide library |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL3350195T3 true PL3350195T3 (pl) | 2021-10-11 |
Family
ID=58289513
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL413941A PL239946B1 (pl) | 2015-09-17 | 2015-09-17 | Sposób syntezy i oczyszczania nukleotydu, zmodyfikowany nukleotyd, cząsteczka DNA i biblioteka oligonukleotydów zawierające zmodyfikowany nukleotyd oraz zastosowanie biblioteki oligonukleotydów |
| PL16846944T PL3350195T3 (pl) | 2015-09-17 | 2016-09-13 | Sposób syntezy i oczyszczania nukleozydu i/lub nukleotydu, zmodyfikowany nukleozyd i/lub nukleotyd, cząsteczka DNA i biblioteka oligonukleotydów zawierające zmodyfikowany nukleozyd i/lub nukleotyd oraz zastosowanie biblioteki oligonukleotydów |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL413941A PL239946B1 (pl) | 2015-09-17 | 2015-09-17 | Sposób syntezy i oczyszczania nukleotydu, zmodyfikowany nukleotyd, cząsteczka DNA i biblioteka oligonukleotydów zawierające zmodyfikowany nukleotyd oraz zastosowanie biblioteki oligonukleotydów |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US10450673B2 (pl) |
| EP (1) | EP3350195B9 (pl) |
| DK (1) | DK3350195T3 (pl) |
| ES (1) | ES2885824T3 (pl) |
| HU (1) | HUE055954T2 (pl) |
| LT (1) | LT3350195T (pl) |
| PL (2) | PL239946B1 (pl) |
| PT (1) | PT3350195T (pl) |
| SI (1) | SI3350195T1 (pl) |
| WO (1) | WO2017048147A1 (pl) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL442186A1 (pl) * | 2022-09-02 | 2024-03-04 | Pure Biologics Spółka Akcyjna | Sposób syntezy i oczyszczania nukleotydu i/lub nukleozydu, zmodyfikowany nukleotyd i/lub nukleozyd, cząsteczka DNA zawierająca jedno- lub dwuniciowy łańcuch oligonukleotydów, biblioteka oligonukleotydów, zastosowanie biblioteki oligonukleotydów |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6175001B1 (en) | 1998-10-16 | 2001-01-16 | The Scripps Research Institute | Functionalized pyrimidine nucleosides and nucleotides and DNA's incorporating same |
| US9096856B2 (en) * | 2007-07-19 | 2015-08-04 | Georgia State University Research Foundation, Inc. | Nucleotides and aptamers containing boronic acid groups having biased binding to glycosylated proteins, and uses thereof |
-
2015
- 2015-09-17 PL PL413941A patent/PL239946B1/pl unknown
-
2016
- 2016-09-13 WO PCT/PL2016/050038 patent/WO2017048147A1/en not_active Ceased
- 2016-09-13 ES ES16846944T patent/ES2885824T3/es active Active
- 2016-09-13 HU HUE16846944A patent/HUE055954T2/hu unknown
- 2016-09-13 DK DK16846944.3T patent/DK3350195T3/da active
- 2016-09-13 SI SI201631318T patent/SI3350195T1/sl unknown
- 2016-09-13 PL PL16846944T patent/PL3350195T3/pl unknown
- 2016-09-13 US US15/760,915 patent/US10450673B2/en active Active
- 2016-09-13 PT PT168469443T patent/PT3350195T/pt unknown
- 2016-09-13 LT LTEPPCT/PL2016/050038T patent/LT3350195T/lt unknown
- 2016-09-13 EP EP16846944.3A patent/EP3350195B9/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| WO2017048147A1 (en) | 2017-03-23 |
| LT3350195T (lt) | 2021-09-10 |
| HUE055954T2 (hu) | 2022-01-28 |
| ES2885824T3 (es) | 2021-12-15 |
| US10450673B2 (en) | 2019-10-22 |
| PT3350195T (pt) | 2021-09-06 |
| SI3350195T1 (sl) | 2021-11-30 |
| PL239946B1 (pl) | 2022-01-31 |
| EP3350195A4 (en) | 2019-07-03 |
| EP3350195B1 (en) | 2021-06-02 |
| US20180265862A1 (en) | 2018-09-20 |
| DK3350195T3 (da) | 2021-08-30 |
| EP3350195A1 (en) | 2018-07-25 |
| EP3350195B9 (en) | 2021-09-29 |
| PL413941A1 (pl) | 2017-03-27 |
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