PL362350A1 - Mutanty chemokin w leczeniu stwardnienia rozsianego - Google Patents

Mutanty chemokin w leczeniu stwardnienia rozsianego

Info

Publication number
PL362350A1
PL362350A1 PL01362350A PL36235001A PL362350A1 PL 362350 A1 PL362350 A1 PL 362350A1 PL 01362350 A PL01362350 A PL 01362350A PL 36235001 A PL36235001 A PL 36235001A PL 362350 A1 PL362350 A1 PL 362350A1
Authority
PL
Poland
Prior art keywords
treatment
multiple sclerosis
chemokine mutants
chemokine
mutants
Prior art date
Application number
PL01362350A
Other languages
English (en)
Other versions
PL204231B1 (pl
Inventor
Amanda Proudfoot
Timothy N.C. Wells
Marie Kosko-Vilbois
Original Assignee
Applied Research Systems Ars Holding N.V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Applied Research Systems Ars Holding N.V. filed Critical Applied Research Systems Ars Holding N.V.
Publication of PL362350A1 publication Critical patent/PL362350A1/pl
Publication of PL204231B1 publication Critical patent/PL204231B1/pl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/521—Chemokines
    • C07K14/523—Beta-chemokines, e.g. RANTES, I-309/TCA-3, MIP-1alpha, MIP-1beta/ACT-2/LD78/SCIF, MCP-1/MCAF, MCP-2, MCP-3, LDCF-1, LDCF-2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Veterinary Medicine (AREA)
  • Neurosurgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Toxicology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PL362350A 2000-10-04 2001-10-03 Zastosowanie mutanta chemokiny CC, kompozycja farmaceutyczna do leczenia stwardnienia rozsianego, skrócona i zmutowana ludzka RANTES i sposób jej wytwarzania, cząsteczka DNA i zawierający ją wektor ekspresyjny oraz komórka gospodarza PL204231B1 (pl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP00121665 2000-10-04

Publications (2)

Publication Number Publication Date
PL362350A1 true PL362350A1 (pl) 2004-10-18
PL204231B1 PL204231B1 (pl) 2009-12-31

Family

ID=8170011

Family Applications (1)

Application Number Title Priority Date Filing Date
PL362350A PL204231B1 (pl) 2000-10-04 2001-10-03 Zastosowanie mutanta chemokiny CC, kompozycja farmaceutyczna do leczenia stwardnienia rozsianego, skrócona i zmutowana ludzka RANTES i sposób jej wytwarzania, cząsteczka DNA i zawierający ją wektor ekspresyjny oraz komórka gospodarza

Country Status (30)

Country Link
US (1) US7402303B2 (pl)
EP (1) EP1326628B1 (pl)
JP (1) JP3908165B2 (pl)
KR (1) KR100837898B1 (pl)
CN (1) CN1285381C (pl)
AR (1) AR030854A1 (pl)
AT (1) ATE265222T1 (pl)
AU (2) AU1591902A (pl)
BG (1) BG66137B1 (pl)
BR (1) BR0114407A (pl)
CA (1) CA2423616C (pl)
CZ (1) CZ303409B6 (pl)
DE (1) DE60103078T2 (pl)
DK (1) DK1326628T3 (pl)
EA (1) EA006137B1 (pl)
EE (1) EE05174B1 (pl)
ES (1) ES2217199T3 (pl)
HR (1) HRP20030215B1 (pl)
HU (1) HUP0302194A3 (pl)
IL (2) IL155178A0 (pl)
MX (1) MXPA03003008A (pl)
NO (1) NO330278B1 (pl)
PL (1) PL204231B1 (pl)
PT (1) PT1326628E (pl)
RS (1) RS50738B (pl)
SI (1) SI1326628T1 (pl)
SK (1) SK287523B6 (pl)
UA (1) UA77950C2 (pl)
WO (1) WO2002028419A2 (pl)
ZA (1) ZA200302315B (pl)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7553483B2 (en) 2001-12-17 2009-06-30 Merck Serono Sa Chemokine mutants acting as chemokine antagonists
JP2005529099A (ja) * 2002-04-04 2005-09-29 アプライド リサーチ システムズ エーアールエス ホールディング ナームロゼ フェンノートシャップ 改善された経口生物学的利用能を有するケモカイン変異体
CA2507008A1 (en) * 2002-12-23 2004-07-29 Applied Research Systems Ars Holding N.V. Use of cc-chemokine mutants against liver diseases
US20090022657A1 (en) * 2003-10-22 2009-01-22 Applied Research Systems Ars Holding N.V. Novel CXCL8 antagonists
AT412785B (de) * 2003-12-04 2005-07-25 Kungl Andreas J Dr Gag-bindungsproteine
ATE322506T1 (de) * 2004-01-19 2006-04-15 Ares Trading Sa Verfahren zur reinigung von in bakterien exprimierten proteinen
GB0412400D0 (en) * 2004-06-03 2004-07-07 Univ Newcastle Treatment of inflammatory conditions
EP2218748B1 (en) * 2005-09-03 2012-10-10 Samsung SDI Co., Ltd. Polybenzoxazine-based compound, electrolyte membrane including the same, and fuel cell employing the electrolyte membrane
GB0614755D0 (en) 2006-07-25 2006-09-06 Univ Geneve Cytokine derivatives
EP2185719B1 (en) 2007-08-02 2013-11-13 NovImmune SA Anti-rantes antibodies and methods of use thereof
WO2011097640A1 (en) * 2010-02-08 2011-08-11 The Trustees Of The University Of Pennsylvania Nucleic acid molecules encoding rantes, and compositions comprising and methods of using the same
EP3813869B1 (en) 2018-05-28 2023-10-18 Université de Genève Ccr5 inhibitor for use in treating a neuroinflammatory disorder that involves cerebral inflammation
WO2022093857A1 (en) * 2020-10-26 2022-05-05 City Of Hope Oncolytic virus compositions and methods for the treatment of cancer

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5739103A (en) * 1993-11-12 1998-04-14 Dana-Farber Cancer Institute Chemokine N-terminal deletion mutations
WO1998006751A1 (en) * 1996-08-16 1998-02-19 Research Corporation Technologies, Inc. Mcp-3, rantes and mip-1alpha receptor antagonists
EP0906954A1 (en) * 1997-09-29 1999-04-07 Applied Research Systems ARS Holding N.V. Amino-terminal truncated c-c chemokines as chemokine antagonist
CA2316447C (en) * 1997-12-23 2009-07-28 Fondazione Centro San Raffaele Del Monte Tabor Rantes mutants and therapeutic applications thereof
AU2740900A (en) * 1999-01-29 2000-08-18 Millennium Pharmaceuticals, Inc. Method of treating demyelinating inflammatory disease using ccr1 antagonists

Also Published As

Publication number Publication date
HRP20030215A2 (en) 2005-02-28
EA200300439A1 (ru) 2003-08-28
PT1326628E (pt) 2004-09-30
MXPA03003008A (es) 2003-07-14
WO2002028419A2 (en) 2002-04-11
CA2423616A1 (en) 2002-04-11
DK1326628T3 (da) 2004-08-09
EE05174B1 (et) 2009-06-15
NO330278B1 (no) 2011-03-21
HUP0302194A3 (en) 2005-12-28
DE60103078T2 (de) 2005-04-07
SI1326628T1 (en) 2004-10-31
CN1477969A (zh) 2004-02-25
IL155178A0 (en) 2003-11-23
AU1591902A (en) 2002-04-15
BG66137B1 (bg) 2011-07-29
AR030854A1 (es) 2003-09-03
ES2217199T3 (es) 2004-11-01
NO20031525D0 (no) 2003-04-03
HK1062811A1 (en) 2004-11-26
BR0114407A (pt) 2003-07-29
HUP0302194A2 (hu) 2003-10-28
EP1326628B1 (en) 2004-04-28
PL204231B1 (pl) 2009-12-31
SK4062003A3 (en) 2003-08-05
RS50738B (sr) 2010-08-31
WO2002028419A3 (en) 2002-06-13
NO20031525L (no) 2003-04-03
UA77950C2 (en) 2007-02-15
BG107685A (bg) 2003-11-28
KR100837898B1 (ko) 2008-06-13
KR20030034238A (ko) 2003-05-01
EP1326628A2 (en) 2003-07-16
CZ2003947A3 (cs) 2003-11-12
CZ303409B6 (cs) 2012-09-05
CN1285381C (zh) 2006-11-22
IL155178A (en) 2009-07-20
ATE265222T1 (de) 2004-05-15
US7402303B2 (en) 2008-07-22
DE60103078D1 (de) 2004-06-03
EE200300139A (et) 2003-06-16
CA2423616C (en) 2010-03-16
JP3908165B2 (ja) 2007-04-25
SK287523B6 (sk) 2011-01-04
HRP20030215B1 (en) 2011-09-30
ZA200302315B (en) 2004-03-25
US20040101509A1 (en) 2004-05-27
YU25703A (sh) 2006-05-25
EA006137B1 (ru) 2005-10-27
JP2004510426A (ja) 2004-04-08
AU2002215919B2 (en) 2005-11-24

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Legal Events

Date Code Title Description
LAPS Decisions on the lapse of the protection rights

Effective date: 20131003