ATE265222T1 - Chemokin mutanten zur behandlung multipler sklerose - Google Patents

Chemokin mutanten zur behandlung multipler sklerose

Info

Publication number
ATE265222T1
ATE265222T1 AT01986265T AT01986265T ATE265222T1 AT E265222 T1 ATE265222 T1 AT E265222T1 AT 01986265 T AT01986265 T AT 01986265T AT 01986265 T AT01986265 T AT 01986265T AT E265222 T1 ATE265222 T1 AT E265222T1
Authority
AT
Austria
Prior art keywords
treatment
multiple sclerosis
chemokine mutants
chemokine
mutants
Prior art date
Application number
AT01986265T
Other languages
English (en)
Inventor
Amanda Proudfoot
Timothy N C Wells
Marie Kosco-Vilbois
Original Assignee
Applied Research Systems
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Applied Research Systems filed Critical Applied Research Systems
Application granted granted Critical
Publication of ATE265222T1 publication Critical patent/ATE265222T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/521—Chemokines
    • C07K14/523—Beta-chemokines, e.g. RANTES, I-309/TCA-3, MIP-1alpha, MIP-1beta/ACT-2/LD78/SCIF, MCP-1/MCAF, MCP-2, MCP-3, LDCF-1, LDCF-2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Toxicology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT01986265T 2000-10-04 2001-10-03 Chemokin mutanten zur behandlung multipler sklerose ATE265222T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP00121665 2000-10-04
PCT/EP2001/011428 WO2002028419A2 (en) 2000-10-04 2001-10-03 Chemokine mutants in the treatment of multiple sclerosis

Publications (1)

Publication Number Publication Date
ATE265222T1 true ATE265222T1 (de) 2004-05-15

Family

ID=8170011

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01986265T ATE265222T1 (de) 2000-10-04 2001-10-03 Chemokin mutanten zur behandlung multipler sklerose

Country Status (30)

Country Link
US (1) US7402303B2 (de)
EP (1) EP1326628B1 (de)
JP (1) JP3908165B2 (de)
KR (1) KR100837898B1 (de)
CN (1) CN1285381C (de)
AR (1) AR030854A1 (de)
AT (1) ATE265222T1 (de)
AU (2) AU2002215919B2 (de)
BG (1) BG66137B1 (de)
BR (1) BR0114407A (de)
CA (1) CA2423616C (de)
CZ (1) CZ303409B6 (de)
DE (1) DE60103078T2 (de)
DK (1) DK1326628T3 (de)
EA (1) EA006137B1 (de)
EE (1) EE05174B1 (de)
ES (1) ES2217199T3 (de)
HR (1) HRP20030215B1 (de)
HU (1) HUP0302194A3 (de)
IL (2) IL155178A0 (de)
MX (1) MXPA03003008A (de)
NO (1) NO330278B1 (de)
PL (1) PL204231B1 (de)
PT (1) PT1326628E (de)
RS (1) RS50738B (de)
SI (1) SI1326628T1 (de)
SK (1) SK287523B6 (de)
UA (1) UA77950C2 (de)
WO (1) WO2002028419A2 (de)
ZA (1) ZA200302315B (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2468790A1 (en) 2001-12-17 2003-06-26 Applied Research Systems Ars Holding N.V. Chemokine mutants acting as chemokine antagonists
AU2003240758B2 (en) 2002-04-04 2008-03-13 Laboratoires Serono Sa Chemokines mutants having improved oral bioavailability
DE60320848D1 (de) * 2002-12-23 2008-06-19 Serono Lab Verwendung von cc-chemokine ccl5/rantes mutanten zur behandlung von lebererkrankungen
US20090022657A1 (en) * 2003-10-22 2009-01-22 Applied Research Systems Ars Holding N.V. Novel CXCL8 antagonists
AT412785B (de) * 2003-12-04 2005-07-25 Kungl Andreas J Dr Gag-bindungsproteine
PT1439191E (pt) * 2004-01-19 2006-06-30 Ares Trading Sa Processo para a purificacao de proteinas expressas de forma bacteriana
GB0412400D0 (en) * 2004-06-03 2004-07-07 Univ Newcastle Treatment of inflammatory conditions
EP1760110B1 (de) * 2005-09-03 2011-11-02 Samsung SDI Co., Ltd. Polybenzoxazin Verbindung, Elektrolyt-Membran enthaltend dieser Verbindung und Elektrolyt-Membran benutzende Brenndstofzell
GB0614755D0 (en) 2006-07-25 2006-09-06 Univ Geneve Cytokine derivatives
WO2009054873A2 (en) 2007-08-02 2009-04-30 Novimmune S.A. Anti-rantes antibodies and methods of use thereof
CA2788902C (en) * 2010-02-08 2019-09-03 The Trustees Of The University Of Pennsylvania Nucleic acid molecules encoding rantes, and compositions comprising and methods of using the same
CN112469430B (zh) 2018-05-28 2024-12-24 日内瓦大学 抑制大脑炎症的方法
WO2022093857A1 (en) * 2020-10-26 2022-05-05 City Of Hope Oncolytic virus compositions and methods for the treatment of cancer

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5739103A (en) * 1993-11-12 1998-04-14 Dana-Farber Cancer Institute Chemokine N-terminal deletion mutations
WO1998006751A1 (en) * 1996-08-16 1998-02-19 Research Corporation Technologies, Inc. Mcp-3, rantes and mip-1alpha receptor antagonists
EP0906954A1 (de) * 1997-09-29 1999-04-07 Applied Research Systems ARS Holding N.V. Aminoterminalen verkürzten C-C Chemokine als Chemokine Antagonist
ATE308617T1 (de) 1997-12-23 2005-11-15 San Raffaele Centro Fond Rantes mutanten und deren therapeutischen anwendungen
CA2361256A1 (en) * 1999-01-29 2000-08-03 James B. Rottman Method of treating demyelinating inflammatory disease using ccr1 antagonists

Also Published As

Publication number Publication date
HRP20030215A2 (en) 2005-02-28
IL155178A (en) 2009-07-20
JP2004510426A (ja) 2004-04-08
HUP0302194A2 (hu) 2003-10-28
WO2002028419A3 (en) 2002-06-13
CN1477969A (zh) 2004-02-25
HRP20030215B1 (en) 2011-09-30
US7402303B2 (en) 2008-07-22
DE60103078D1 (de) 2004-06-03
SK4062003A3 (en) 2003-08-05
SI1326628T1 (en) 2004-10-31
IL155178A0 (en) 2003-11-23
NO20031525L (no) 2003-04-03
CZ2003947A3 (cs) 2003-11-12
CN1285381C (zh) 2006-11-22
RS50738B (sr) 2010-08-31
SK287523B6 (sk) 2011-01-04
BG107685A (bg) 2003-11-28
HK1062811A1 (en) 2004-11-26
PL362350A1 (en) 2004-10-18
DE60103078T2 (de) 2005-04-07
EE200300139A (et) 2003-06-16
ZA200302315B (en) 2004-03-25
CA2423616A1 (en) 2002-04-11
WO2002028419A2 (en) 2002-04-11
ES2217199T3 (es) 2004-11-01
NO20031525D0 (no) 2003-04-03
DK1326628T3 (da) 2004-08-09
EA006137B1 (ru) 2005-10-27
BG66137B1 (bg) 2011-07-29
AU2002215919B2 (en) 2005-11-24
AU1591902A (en) 2002-04-15
AR030854A1 (es) 2003-09-03
CA2423616C (en) 2010-03-16
JP3908165B2 (ja) 2007-04-25
CZ303409B6 (cs) 2012-09-05
EP1326628A2 (de) 2003-07-16
EA200300439A1 (ru) 2003-08-28
HUP0302194A3 (en) 2005-12-28
KR100837898B1 (ko) 2008-06-13
KR20030034238A (ko) 2003-05-01
EE05174B1 (et) 2009-06-15
BR0114407A (pt) 2003-07-29
MXPA03003008A (es) 2003-07-14
US20040101509A1 (en) 2004-05-27
EP1326628B1 (de) 2004-04-28
UA77950C2 (en) 2007-02-15
PL204231B1 (pl) 2009-12-31
YU25703A (sh) 2006-05-25
NO330278B1 (no) 2011-03-21
PT1326628E (pt) 2004-09-30

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