PL371269A1 - Pochodne benzimidazolu podstawione grupą 1-fenylo-2-heteroarylową, ich zastosowanie do wytwarzania środków leczniczych do leczenia schorzeń immunologicznych - Google Patents

Pochodne benzimidazolu podstawione grupą 1-fenylo-2-heteroarylową, ich zastosowanie do wytwarzania środków leczniczych do leczenia schorzeń immunologicznych

Info

Publication number
PL371269A1
PL371269A1 PL03371269A PL37126903A PL371269A1 PL 371269 A1 PL371269 A1 PL 371269A1 PL 03371269 A PL03371269 A PL 03371269A PL 37126903 A PL37126903 A PL 37126903A PL 371269 A1 PL371269 A1 PL 371269A1
Authority
PL
Poland
Prior art keywords
heteroaryl
phenyl
treatment
drugs used
benzimidazole derivatives
Prior art date
Application number
PL03371269A
Other languages
English (en)
Other versions
PL216233B1 (pl
Inventor
Thorsten Blume
Wolfgang Halfbrodt
Joachim Kuhnke
Ursula Mönning
Bernd Elger
Herbert Schneider
Original Assignee
Schering Aktiengesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Aktiengesellschaft filed Critical Schering Aktiengesellschaft
Publication of PL371269A1 publication Critical patent/PL371269A1/pl
Publication of PL216233B1 publication Critical patent/PL216233B1/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pulmonology (AREA)
  • Transplantation (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
PL371269A 2002-02-15 2003-01-17 Pochodne benzimidazolu, ich zastosowanie oraz kompozycja farmaceutyczna je zawierająca PL216233B1 (pl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE10207844A DE10207844A1 (de) 2002-02-15 2002-02-15 1-Phenyl-2-heteroaryl-substituierte Benzimidazolderivate, deren Verwendung zur Herstellung von Arzneimitteln sowie diese Derivate enthaltende pharmazeutische Präparate

Publications (2)

Publication Number Publication Date
PL371269A1 true PL371269A1 (pl) 2005-06-13
PL216233B1 PL216233B1 (pl) 2014-03-31

Family

ID=27674913

Family Applications (1)

Application Number Title Priority Date Filing Date
PL371269A PL216233B1 (pl) 2002-02-15 2003-01-17 Pochodne benzimidazolu, ich zastosowanie oraz kompozycja farmaceutyczna je zawierająca

Country Status (30)

Country Link
EP (1) EP1474415B1 (pl)
JP (1) JP4739675B2 (pl)
KR (1) KR101027556B1 (pl)
CN (1) CN1317274C (pl)
AR (1) AR038492A1 (pl)
AT (1) ATE517881T1 (pl)
AU (1) AU2003205624B2 (pl)
BR (1) BR0307723A (pl)
CA (1) CA2475780C (pl)
CR (1) CR7442A (pl)
CY (1) CY1113230T1 (pl)
DE (1) DE10207844A1 (pl)
DK (1) DK1474415T3 (pl)
EC (1) ECSP045296A (pl)
ES (1) ES2369662T3 (pl)
IL (1) IL163431A (pl)
MX (1) MXPA04007949A (pl)
NO (1) NO329667B1 (pl)
NZ (1) NZ534660A (pl)
PE (1) PE20030941A1 (pl)
PL (1) PL216233B1 (pl)
PT (1) PT1474415E (pl)
RS (1) RS51831B (pl)
RU (1) RU2325384C2 (pl)
SI (1) SI1474415T1 (pl)
TW (1) TWI328583B (pl)
UA (1) UA81243C2 (pl)
UY (1) UY27661A1 (pl)
WO (1) WO2003068766A1 (pl)
ZA (1) ZA200407381B (pl)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2309154C9 (ru) 2002-03-27 2016-09-27 Глэксо Груп Лимитед 3-фенилсульфонил-8-пиперазин-1-ил-хинолины, обладающие аффинностью к 5-нт6 рецептору, способы их получения (варианты)
MXPA05012459A (es) * 2003-05-19 2006-02-22 Irm Llc Compuestos y composiciones inmunosupresoras.
WO2014044611A1 (en) 2012-09-20 2014-03-27 Bayer Pharma Aktiengesellschaft 1-aryl-2-heteroaryl benzimidazoles for the induction of neuronal regeneration

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4430502A (en) * 1982-08-13 1984-02-07 The Upjohn Company Pyridinyl substituted benzimidazoles and quinoxalines
ATE163290T1 (de) * 1991-06-24 1998-03-15 Neurosearch As Imidazol-verbindungen, verfahren zu ihrer herstellung und ihre anwendung
DE4129603A1 (de) * 1991-09-06 1993-03-11 Thomae Gmbh Dr K Kondensierte 5-gliedrige heterocyclen, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE4330959A1 (de) * 1993-09-09 1995-03-16 Schering Ag Neue Benzimidazolderivate, Verfahren zu ihrer Herstellung und ihre pharmazeutische Verwendung
EP0980359B1 (en) * 1997-05-01 2004-06-23 Nissan Chemical Industries, Ltd. Benzimidazole derivative
EP1214330A1 (en) * 1999-09-21 2002-06-19 LION Bioscience AG Benzimidazole derivatives and combinatorial libraries thereof
EE05515B1 (et) 2000-01-14 2012-02-15 Schering@Aktiengesellschaft 1 2 diarlbensimidasoolid mikrogliia aktivatsiooniga seotud haiguste raviks
US7115645B2 (en) * 2000-01-14 2006-10-03 Schering Aktiengesellschaft 1,2 diarylbenzimidazoles and their pharmaceutical use
DE10207843A1 (de) * 2002-02-15 2003-09-04 Schering Ag Mikrolia-Inhibitoren zur Unterbrechung von Interleukin 12 und IFN-gamma vermittelten Immunreaktionen

Also Published As

Publication number Publication date
RS51831B (sr) 2012-02-29
CA2475780A1 (en) 2003-08-21
TW200303307A (en) 2003-09-01
JP4739675B2 (ja) 2011-08-03
RS71404A (sr) 2006-10-27
CN1633429A (zh) 2005-06-29
RU2004127678A (ru) 2005-07-10
SI1474415T1 (sl) 2011-12-30
NO329667B1 (no) 2010-11-29
UA81243C2 (en) 2007-12-25
PT1474415E (pt) 2011-10-13
UY27661A1 (es) 2003-09-30
WO2003068766A1 (de) 2003-08-21
AU2003205624B2 (en) 2009-08-27
AU2003205624A1 (en) 2003-09-04
ZA200407381B (en) 2005-11-30
KR20040081795A (ko) 2004-09-22
PL216233B1 (pl) 2014-03-31
TWI328583B (en) 2010-08-11
ECSP045296A (es) 2004-10-26
CY1113230T1 (el) 2016-04-13
KR101027556B1 (ko) 2011-04-06
MXPA04007949A (es) 2004-11-26
IL163431A (en) 2010-11-30
EP1474415A1 (de) 2004-11-10
DE10207844A1 (de) 2003-09-04
JP2005521686A (ja) 2005-07-21
AR038492A1 (es) 2005-01-19
BR0307723A (pt) 2005-01-25
NZ534660A (en) 2006-02-24
RU2325384C2 (ru) 2008-05-27
CR7442A (es) 2006-02-06
CN1317274C (zh) 2007-05-23
ES2369662T3 (es) 2011-12-02
CA2475780C (en) 2011-08-02
NO20043841L (no) 2004-11-12
ATE517881T1 (de) 2011-08-15
EP1474415B1 (de) 2011-07-27
DK1474415T3 (da) 2011-11-21
PE20030941A1 (es) 2004-01-17

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