PL374967A1 - Kompozycje pirazoli użyteczne jako inhibitory GSK-3 - Google Patents

Kompozycje pirazoli użyteczne jako inhibitory GSK-3

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Publication number
PL374967A1
PL374967A1 PL03374967A PL37496703A PL374967A1 PL 374967 A1 PL374967 A1 PL 374967A1 PL 03374967 A PL03374967 A PL 03374967A PL 37496703 A PL37496703 A PL 37496703A PL 374967 A1 PL374967 A1 PL 374967A1
Authority
PL
Poland
Prior art keywords
gsk
inhibitors
compositions useful
pyrazole compositions
pyrazole
Prior art date
Application number
PL03374967A
Other languages
English (en)
Inventor
Cornelia J. Forster
Larry C. Park
Marion W. Wannamaker
Yung-Mae Yao
Original Assignee
Vertex Pharmaceuticals Incorporated
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vertex Pharmaceuticals Incorporated filed Critical Vertex Pharmaceuticals Incorporated
Publication of PL374967A1 publication Critical patent/PL374967A1/pl

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
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    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
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    • A61P37/00—Drugs for immunological or allergic disorders
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    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
    • A—HUMAN NECESSITIES
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    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Diabetes (AREA)
  • Pulmonology (AREA)
  • Psychiatry (AREA)
  • Psychology (AREA)
  • Obesity (AREA)
  • Hospice & Palliative Care (AREA)
  • Ophthalmology & Optometry (AREA)
  • Vascular Medicine (AREA)
  • Virology (AREA)
  • Hematology (AREA)
  • Rheumatology (AREA)
  • AIDS & HIV (AREA)
  • Communicable Diseases (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Oncology (AREA)
PL03374967A 2002-08-02 2003-07-31 Kompozycje pirazoli użyteczne jako inhibitory GSK-3 PL374967A1 (pl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US40096702P 2002-08-02 2002-08-02

Publications (1)

Publication Number Publication Date
PL374967A1 true PL374967A1 (pl) 2005-11-14

Family

ID=31495907

Family Applications (1)

Application Number Title Priority Date Filing Date
PL03374967A PL374967A1 (pl) 2002-08-02 2003-07-31 Kompozycje pirazoli użyteczne jako inhibitory GSK-3

Country Status (25)

Country Link
US (2) US7491730B2 (pl)
EP (1) EP1532145B1 (pl)
JP (3) JP4733388B2 (pl)
KR (1) KR20050032105A (pl)
CN (2) CN1319968C (pl)
AR (1) AR040773A1 (pl)
AT (1) ATE339419T1 (pl)
AU (2) AU2003257078B2 (pl)
BR (1) BR0313176A (pl)
CA (1) CA2494100C (pl)
CO (1) CO5700772A2 (pl)
DE (1) DE60308387T2 (pl)
DK (1) DK1532145T3 (pl)
EA (1) EA200500299A1 (pl)
EC (1) ECSP055640A (pl)
ES (1) ES2273043T3 (pl)
IL (1) IL166620A (pl)
MX (1) MXPA05001367A (pl)
NO (1) NO20051100L (pl)
NZ (2) NZ538426A (pl)
PL (1) PL374967A1 (pl)
PT (1) PT1532145E (pl)
TW (1) TWI324157B (pl)
WO (1) WO2004013140A1 (pl)
ZA (1) ZA200501124B (pl)

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