PL404926A1 - Nowy sposób rozdzielania epotylonów, nowy szczep Sorangium cellulosum, nowe krystaliczne postacie epotylonu B, kompozycje farmaceutyczne je zawierajace oraz zastosowanie nowych, krystalicznych postaci epotylonu B - Google Patents

Nowy sposób rozdzielania epotylonów, nowy szczep Sorangium cellulosum, nowe krystaliczne postacie epotylonu B, kompozycje farmaceutyczne je zawierajace oraz zastosowanie nowych, krystalicznych postaci epotylonu B

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Publication number
PL404926A1
PL404926A1 PL404926A PL40492699A PL404926A1 PL 404926 A1 PL404926 A1 PL 404926A1 PL 404926 A PL404926 A PL 404926A PL 40492699 A PL40492699 A PL 40492699A PL 404926 A1 PL404926 A1 PL 404926A1
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PL
Poland
Prior art keywords
new
epothilone
crystalline forms
pharmaceutical compositions
compositions containing
Prior art date
Application number
PL404926A
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English (en)
Inventor
Hans Hofmann
Marion Mahnke
Klaus Memmert
Frank Petersen
Thomas Schupp
Ernst Kusters
Michael Mutz
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Novartis Ag
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Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of PL404926A1 publication Critical patent/PL404926A1/pl

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/16—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing two or more hetero rings
    • C12P17/167—Heterorings having sulfur atoms as ring heteroatoms, e.g. vitamin B1, thiamine nucleus and open chain analogs
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
    • C12P17/181—Heterocyclic compounds containing oxygen atoms as the only ring heteroatoms in the condensed system, e.g. Salinomycin, Septamycin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2299/00—Coordinates from 3D structures of peptides, e.g. proteins or enzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Saccharide Compounds (AREA)

Abstract

Wynalazek obejmuje sposób rozdzielania epotylonów, nowy szczep Sorangium cellulosum, nowe, krystaliczne postacie epotylonu B, kompozycje farmaceutyczne je zawierajace oraz zastosowanie nowych, krystalicznych postaci epotylonu B.
PL404926A 1998-02-19 1999-02-17 Nowy sposób rozdzielania epotylonów, nowy szczep Sorangium cellulosum, nowe krystaliczne postacie epotylonu B, kompozycje farmaceutyczne je zawierajace oraz zastosowanie nowych, krystalicznych postaci epotylonu B PL404926A1 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH39698 1998-02-19
CH100798 1998-05-05

Publications (1)

Publication Number Publication Date
PL404926A1 true PL404926A1 (pl) 2013-12-09

Family

ID=25684443

Family Applications (2)

Application Number Title Priority Date Filing Date
PL342423A PL196787B1 (pl) 1998-02-19 1999-02-17 Nowy sposób zatężania epotylonów, nowe pożywki hodowlane oraz nowy sposób wytwarzania epotylonów
PL404926A PL404926A1 (pl) 1998-02-19 1999-02-17 Nowy sposób rozdzielania epotylonów, nowy szczep Sorangium cellulosum, nowe krystaliczne postacie epotylonu B, kompozycje farmaceutyczne je zawierajace oraz zastosowanie nowych, krystalicznych postaci epotylonu B

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PL342423A PL196787B1 (pl) 1998-02-19 1999-02-17 Nowy sposób zatężania epotylonów, nowe pożywki hodowlane oraz nowy sposób wytwarzania epotylonów

Country Status (24)

Country Link
US (8) US6194181B1 (pl)
EP (2) EP1054994B1 (pl)
JP (3) JP3681109B2 (pl)
KR (4) KR100873526B1 (pl)
CN (2) CN1286839C (pl)
AT (1) ATE282710T1 (pl)
AU (1) AU746294B2 (pl)
BR (1) BR9908119A (pl)
CA (1) CA2318818A1 (pl)
CZ (1) CZ301517B6 (pl)
DE (1) DE69921966T2 (pl)
DK (1) DK1054994T3 (pl)
ES (1) ES2233028T3 (pl)
HU (1) HU225851B1 (pl)
IL (4) IL137691A0 (pl)
NO (4) NO322588B1 (pl)
NZ (2) NZ525622A (pl)
PL (2) PL196787B1 (pl)
PT (1) PT1054994E (pl)
RU (1) RU2268306C2 (pl)
SI (1) SI1054994T1 (pl)
SK (3) SK286517B6 (pl)
TR (2) TR200101634T2 (pl)
WO (1) WO1999042602A2 (pl)

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