PL4401833T3 - Związki modulujące receptor gpr52 - Google Patents

Związki modulujące receptor gpr52

Info

Publication number
PL4401833T3
PL4401833T3 PL22778038.4T PL22778038T PL4401833T3 PL 4401833 T3 PL4401833 T3 PL 4401833T3 PL 22778038 T PL22778038 T PL 22778038T PL 4401833 T3 PL4401833 T3 PL 4401833T3
Authority
PL
Poland
Prior art keywords
modulating compounds
receptor modulating
gpr52
gpr52 receptor
compounds
Prior art date
Application number
PL22778038.4T
Other languages
English (en)
Inventor
Stephen Paul Watson
Nigel Alan Swain
Michael Alistair O'brien
Original Assignee
Nxera Pharma Uk Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nxera Pharma Uk Limited filed Critical Nxera Pharma Uk Limited
Publication of PL4401833T3 publication Critical patent/PL4401833T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/661Phosphorus acids or esters thereof not having P—C bonds, e.g. fosfosal, dichlorvos, malathion or mevinphos
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/675Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6558Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
    • C07F9/65583Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system each of the hetero rings containing nitrogen as ring hetero atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
PL22778038.4T 2021-09-15 2022-09-15 Związki modulujące receptor gpr52 PL4401833T3 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB2113186.7A GB202113186D0 (en) 2021-09-15 2021-09-15 GPR52 Modulator compounds
PCT/GB2022/052328 WO2023041909A1 (en) 2021-09-15 2022-09-15 Gpr52 modulator compounds

Publications (1)

Publication Number Publication Date
PL4401833T3 true PL4401833T3 (pl) 2026-02-16

Family

ID=78149263

Family Applications (1)

Application Number Title Priority Date Filing Date
PL22778038.4T PL4401833T3 (pl) 2021-09-15 2022-09-15 Związki modulujące receptor gpr52

Country Status (22)

Country Link
US (1) US20240376070A1 (pl)
EP (1) EP4401833B1 (pl)
JP (1) JP2024535860A (pl)
KR (1) KR20240058852A (pl)
CN (1) CN117999258A (pl)
AU (1) AU2022348201A1 (pl)
CA (1) CA3232606A1 (pl)
CL (1) CL2024000742A1 (pl)
DK (1) DK4401833T3 (pl)
ES (1) ES3053759T3 (pl)
FI (1) FI4401833T3 (pl)
GB (1) GB202113186D0 (pl)
HR (1) HRP20251420T1 (pl)
IL (1) IL311015A (pl)
LT (1) LT4401833T (pl)
MX (1) MX2024003248A (pl)
PL (1) PL4401833T3 (pl)
PT (1) PT4401833T (pl)
RS (1) RS67399B1 (pl)
SI (1) SI4401833T1 (pl)
SM (1) SMT202500449T1 (pl)
WO (1) WO2023041909A1 (pl)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW202206413A (zh) 2020-04-22 2022-02-16 美商紐羅克里生物科學有限公司 Gpr52調節劑及其使用方法
WO2025252061A1 (zh) * 2024-06-04 2025-12-11 海思科医药集团股份有限公司 一种gpr52激动剂及其在医药上的应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2784316T3 (es) 2015-04-29 2020-09-24 Arena Pharm Inc 1-Heteroaril-indolin-4-carboxamidas como moduladores de GPR52 útiles para el tratamiento o la prevención de trastornos relacionados con el mismo
US10633350B2 (en) * 2017-09-13 2020-04-28 Novartis Ag Diphenyl derivatives and uses thereof
EP4055016A1 (en) * 2019-11-08 2022-09-14 Heptares Therapeutics Limited Gpr52 modulator compounds
GB202003668D0 (en) 2020-03-13 2020-04-29 Heptares Therapeutics Ltd GPR52 Modulator compounds

Also Published As

Publication number Publication date
DK4401833T3 (da) 2025-11-17
EP4401833A1 (en) 2024-07-24
GB202113186D0 (en) 2021-10-27
SI4401833T1 (sl) 2026-01-30
US20240376070A1 (en) 2024-11-14
ES3053759T3 (en) 2026-01-26
IL311015A (en) 2024-04-01
LT4401833T (lt) 2025-12-10
SMT202500449T1 (it) 2026-01-12
CL2024000742A1 (es) 2024-09-27
KR20240058852A (ko) 2024-05-07
WO2023041909A1 (en) 2023-03-23
HRP20251420T1 (hr) 2026-01-02
EP4401833B1 (en) 2025-10-22
FI4401833T3 (fi) 2025-11-25
CA3232606A1 (en) 2023-03-23
MX2024003248A (es) 2024-04-02
RS67399B1 (sr) 2025-11-28
PT4401833T (pt) 2025-11-14
CN117999258A (zh) 2024-05-07
JP2024535860A (ja) 2024-10-02
AU2022348201A1 (en) 2024-03-28

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