PL448793A1 - Method of producing sesamol - Google Patents

Method of producing sesamol

Info

Publication number
PL448793A1
PL448793A1 PL448793A PL44879324A PL448793A1 PL 448793 A1 PL448793 A1 PL 448793A1 PL 448793 A PL448793 A PL 448793A PL 44879324 A PL44879324 A PL 44879324A PL 448793 A1 PL448793 A1 PL 448793A1
Authority
PL
Poland
Prior art keywords
days
sesamol
producing
producing sesamol
culture
Prior art date
Application number
PL448793A
Other languages
Polish (pl)
Inventor
El-Sayed Ramadan El-Sayed Ali
Ewa Szczepańska
Filip Boratyński
Shaimaa Mousa
Original Assignee
Uniwersytet Przyrodniczy we Wrocławiu
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Uniwersytet Przyrodniczy we Wrocławiu filed Critical Uniwersytet Przyrodniczy we Wrocławiu
Priority to PL448793A priority Critical patent/PL448793A1/en
Publication of PL448793A1 publication Critical patent/PL448793A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02—Oxygen as only ring hetero atoms
    • C12P17/04—Oxygen as only ring hetero atoms containing a five-membered hetero ring, e.g. griseofulvin, vitamin C
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/62—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/64—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/645—Fungi ; Processes using fungi

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Przedmiotem zgłoszenia jest sposób wytwarzania sezamolu charakteryzujący się tym, że do podłoża odpowiedniego dla grzybów strzępkowych wprowadza się szczep Monascus ruber m22, następnie po upływie co najmniej 5 dni do hodowli wprowadza się substrat, którym jest kwas piperonylowy o wzorze 1, w postaci soli amonowej, transformację prowadzi się w temperaturze pokojowej od 20 do 25 stopni Celsjusza, przy ciągłym wstrząsaniu, co najmniej 2 dni, po czym produkt ekstrahuje się rozpuszczalnikiem organicznym niemieszającym się z wodą i oczyszcza chromatograficznie.The subject of the application is a method for producing sesamol characterized in that the strain Monascus ruber m22 is introduced into a medium suitable for filamentous fungi, then after at least 5 days a substrate, which is piperonylic acid of formula 1, in the form of an ammonium salt, is introduced into the culture, the transformation is carried out at room temperature from 20 to 25 degrees Celsius, with continuous shaking, for at least 2 days, after which the product is extracted with an organic solvent immiscible with water and purified chromatographically.

PL448793A 2024-06-11 2024-06-11 Method of producing sesamol PL448793A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PL448793A PL448793A1 (en) 2024-06-11 2024-06-11 Method of producing sesamol

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PL448793A PL448793A1 (en) 2024-06-11 2024-06-11 Method of producing sesamol

Publications (1)

Publication Number Publication Date
PL448793A1 true PL448793A1 (en) 2025-12-15

Family

ID=98005357

Family Applications (1)

Application Number Title Priority Date Filing Date
PL448793A PL448793A1 (en) 2024-06-11 2024-06-11 Method of producing sesamol

Country Status (1)

Country Link
PL (1) PL448793A1 (en)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004105064A (en) * 2002-09-18 2004-04-08 Mercian Corp Sesamol manufacturing method
CN113563301A (en) * 2021-07-27 2021-10-29 绵阳三香汇生物科技有限公司 Synthesis process of 3, 4-methylenedioxyphenol
CN113666903A (en) * 2021-09-01 2021-11-19 重庆化工职业学院 A kind of preparation method of sesamol

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004105064A (en) * 2002-09-18 2004-04-08 Mercian Corp Sesamol manufacturing method
CN113563301A (en) * 2021-07-27 2021-10-29 绵阳三香汇生物科技有限公司 Synthesis process of 3, 4-methylenedioxyphenol
CN113666903A (en) * 2021-09-01 2021-11-19 重庆化工职业学院 A kind of preparation method of sesamol

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