PT88251A - Processo para a preparacao de novos derivados de ariloxi-indenamina com actividade antidepressiva e de composicoes farmaceuticas que os contem - Google Patents

Processo para a preparacao de novos derivados de ariloxi-indenamina com actividade antidepressiva e de composicoes farmaceuticas que os contem

Info

Publication number
PT88251A
PT88251A PT88251A PT8825188A PT88251A PT 88251 A PT88251 A PT 88251A PT 88251 A PT88251 A PT 88251A PT 8825188 A PT8825188 A PT 8825188A PT 88251 A PT88251 A PT 88251A
Authority
PT
Portugal
Prior art keywords
indenamine
derivatives
contain
pharmaceutical compositions
preparing new
Prior art date
Application number
PT88251A
Other languages
English (en)
Other versions
PT88251B (pt
Inventor
Jules Freedman
Mark William Dudley
Original Assignee
Merrell Dow Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma
Publication of PT88251A publication Critical patent/PT88251A/pt
Publication of PT88251B publication Critical patent/PT88251B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C217/48—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/096—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/275—Nitriles; Isonitriles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Saccharide Compounds (AREA)
  • Steroid Compounds (AREA)
PT88251A 1987-08-14 1988-08-11 Processo para a preparacao de novos derivados de ariloxi-indenamina com actividade antidepressiva e de composicoes farmaceuticas que os contem PT88251B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US8566587A 1987-08-14 1987-08-14

Publications (2)

Publication Number Publication Date
PT88251A true PT88251A (pt) 1989-06-30
PT88251B PT88251B (pt) 1995-03-01

Family

ID=22193153

Family Applications (1)

Application Number Title Priority Date Filing Date
PT88251A PT88251B (pt) 1987-08-14 1988-08-11 Processo para a preparacao de novos derivados de ariloxi-indenamina com actividade antidepressiva e de composicoes farmaceuticas que os contem

Country Status (19)

Country Link
US (2) US5880120A (pt)
EP (1) EP0303961B1 (pt)
JP (1) JP2650045B2 (pt)
KR (1) KR0126137B1 (pt)
CN (1) CN1021323C (pt)
AT (1) ATE104269T1 (pt)
AU (2) AU606444B2 (pt)
CA (1) CA1327795C (pt)
DE (1) DE3889032T2 (pt)
DK (1) DK454688A (pt)
ES (1) ES2054747T3 (pt)
FI (1) FI91852C (pt)
HU (1) HU204504B (pt)
IE (1) IE63082B1 (pt)
IL (1) IL87412A (pt)
NO (1) NO167913C (pt)
NZ (1) NZ225758A (pt)
PT (1) PT88251B (pt)
ZA (1) ZA885824B (pt)

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Also Published As

Publication number Publication date
NO883595L (no) 1989-02-15
IL87412A0 (en) 1989-01-31
IE63082B1 (en) 1995-03-22
US5880120A (en) 1999-03-09
US6136803A (en) 2000-10-24
EP0303961B1 (en) 1994-04-13
FI91852C (fi) 1994-08-25
IL87412A (en) 1995-05-26
NZ225758A (en) 1990-10-26
CA1327795C (en) 1994-03-15
DE3889032D1 (de) 1994-05-19
IE882484L (en) 1989-02-14
DE3889032T2 (de) 1994-08-11
CN1033043A (zh) 1989-05-24
ZA885824B (en) 1989-04-26
DK454688A (da) 1989-02-15
KR0126137B1 (ko) 1997-12-26
JP2650045B2 (ja) 1997-09-03
NO883595D0 (no) 1988-08-12
ES2054747T3 (es) 1994-08-16
EP0303961A3 (en) 1989-05-17
AU624278B2 (en) 1992-06-04
HU204504B (en) 1992-01-28
NO167913B (no) 1991-09-16
KR890003671A (ko) 1989-04-17
PT88251B (pt) 1995-03-01
JPS6466151A (en) 1989-03-13
DK454688D0 (da) 1988-08-12
AU6598990A (en) 1991-01-24
ATE104269T1 (de) 1994-04-15
FI91852B (fi) 1994-05-13
EP0303961A2 (en) 1989-02-22
HUT51593A (en) 1990-05-28
NO167913C (no) 1991-12-27
CN1021323C (zh) 1993-06-23
AU606444B2 (en) 1991-02-07
AU2057988A (en) 1989-02-16
FI883739A0 (fi) 1988-08-11
FI883739A7 (fi) 1989-02-15

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