PT94037A - Processo para a preparacao de factor de crescimento epidermico (epidermal growth factor) e de composicoes farmaceuticas que o contem - Google Patents

Processo para a preparacao de factor de crescimento epidermico (epidermal growth factor) e de composicoes farmaceuticas que o contem

Info

Publication number
PT94037A
PT94037A PT94037A PT9403790A PT94037A PT 94037 A PT94037 A PT 94037A PT 94037 A PT94037 A PT 94037A PT 9403790 A PT9403790 A PT 9403790A PT 94037 A PT94037 A PT 94037A
Authority
PT
Portugal
Prior art keywords
pharmaceutical compositions
growth factor
epidermal growth
preparing epidermal
preparing
Prior art date
Application number
PT94037A
Other languages
English (en)
Other versions
PT94037B (pt
Inventor
John K Cini
Amy L Finkenaur
Original Assignee
Ethicon Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ethicon Inc filed Critical Ethicon Inc
Publication of PT94037A publication Critical patent/PT94037A/pt
Publication of PT94037B publication Critical patent/PT94037B/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/28—Compounds containing heavy metals
    • A61K31/315—Zinc compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1808—Epidermal growth factor [EGF] urogastrone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dermatology (AREA)
  • Inorganic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Inorganic Compounds Of Heavy Metals (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
PT94037A 1989-05-16 1990-05-15 Processo para a preparacao de factor de crescimento epidermico (epidermal growth factor) e de composicoes farmaceuticas que o contem PT94037B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/353,131 US5130298A (en) 1989-05-16 1989-05-16 Stabilized compositions containing epidermal growth factor

Publications (2)

Publication Number Publication Date
PT94037A true PT94037A (pt) 1991-01-08
PT94037B PT94037B (pt) 1996-11-29

Family

ID=23387889

Family Applications (1)

Application Number Title Priority Date Filing Date
PT94037A PT94037B (pt) 1989-05-16 1990-05-15 Processo para a preparacao de factor de crescimento epidermico (epidermal growth factor) e de composicoes farmaceuticas que o contem

Country Status (11)

Country Link
US (1) US5130298A (pt)
EP (1) EP0398619B1 (pt)
JP (1) JP2763815B2 (pt)
KR (1) KR900017580A (pt)
AU (1) AU630952B2 (pt)
CA (1) CA2016659C (pt)
DE (1) DE69002795T2 (pt)
DK (1) DK0398619T3 (pt)
ES (1) ES2058799T3 (pt)
GR (1) GR1000392B (pt)
PT (1) PT94037B (pt)

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US6048545A (en) * 1994-06-24 2000-04-11 Biozone Laboratories, Inc. Liposomal delivery by iontophoresis
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AU7678196A (en) * 1995-11-13 1997-06-05 Minimed, Inc. Methods and compositions for the delivery of monomeric proteins
JP2001508648A (ja) 1996-11-06 2001-07-03 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア 腫瘍壊死因子レセプター放出酵素、酵素を含む組成物、およびその使用方法
US6593456B1 (en) * 1996-11-06 2003-07-15 The Regents Of The University Of California Tumor necrosis factor receptor releasing enzyme
US20050191661A1 (en) * 1996-11-06 2005-09-01 Tetsuya Gatanaga Treatment of inflammatory disease by cleaving TNF receptors
US6495532B1 (en) * 1997-03-19 2002-12-17 Sky High, Llc Compositions containing lysophosphotidic acids which inhibit apoptosis and uses thereof
US6949528B1 (en) * 1998-03-18 2005-09-27 Goddard John G Compositions containing lysophosphatidic acids which inhibit apoptosis and uses thereof
US7033615B2 (en) * 1999-07-09 2006-04-25 Cancer2 Inc. Methods for regulating levels of zinc, cadmium and calcium in humans and for diagnosing, or screening for the risk of developing, diseases associated with abnormal levels of cadmium, zinc and calcium in body fluids and tissues
US6541447B1 (en) 1999-09-01 2003-04-01 B & M Healthcare Technologies, Inc. Wound healing composition and method for use thereof
GB0001621D0 (en) 2000-01-26 2000-03-15 Astrazeneca Ab Pharmaceutical compositions
US20060063738A1 (en) * 2000-02-28 2006-03-23 Sky High, Llc Compositions containing lysophosphotidic acids which inhibit apoptosis and uses thereof
US7015199B1 (en) * 2000-06-02 2006-03-21 Neirinckx Rudi D Treatment of psoriasis through down-regulation of the EGF-receptor with topically-applied EGF
US20070087965A1 (en) * 2005-10-03 2007-04-19 Neirinckx Rudi D Treatment of psoriasis through down-regulation of the egf-receptor with topically applied egf
AU2001279073B2 (en) 2000-07-28 2006-08-24 Christopher J. Murphy Transplant media
CU23043A1 (es) * 2001-12-20 2005-05-20 Ct Ingenieria Genetica Biotech Composicion farmaceutica que contiene factor de crecimiento epidrmico (egf) para la prevencion de la amputacion de pie diabetico.
EP1482966B1 (en) * 2002-03-12 2014-05-14 Bio-Click Technologies Ltd Method and composition for treating skin wounds with epidermal growth factor
SE0202719D0 (sv) * 2002-09-13 2002-09-13 Pharmacia Ab Process for mfg crystals of growth hormone
US20050214382A1 (en) * 2004-03-29 2005-09-29 Erning Xia Zinc preservative composition and method of use
US20070207209A1 (en) * 2004-08-27 2007-09-06 Murphy Christopher J Trophic factor combinations for nervous system treatment
MX2007014856A (es) 2005-05-27 2008-02-21 Bharat Biotech Int Ltd Composicion de factor de crecimiento epidermico, un proceso para el mismo y su aplicacion.
CU23411B6 (es) * 2005-12-29 2009-09-08 Ct Ingenieria Genetica Biotech Uso tópico del factor de crecimiento epidérmico en liposomas para prevenir la amputación del pie diabético
CU23388B6 (es) * 2006-01-31 2009-07-16 Ct Ingenieria Genetica Biotech Composición farmacéutica de microesferas para prevenir la amputación del pie diabético
TWI394564B (zh) * 2006-09-21 2013-05-01 Alcon Res Ltd 自行保存型水性藥學組成物
WO2008042619A2 (en) * 2006-09-28 2008-04-10 Alcon Research, Ltd. Self-preserved aqueous pharmaceutical compositions
CU23526B6 (es) * 2006-10-03 2010-05-19 Ct Ingenieria Genetica Biotech Método para la restauración morfofuncional de nervios periféricos en la neuropatía diabética
KR100784134B1 (ko) * 2006-10-09 2007-12-12 주식회사 대웅 상피세포성장인자를 함유하는 안정한 구내염 치료용 액상조성물
PT2254549E (pt) * 2008-03-17 2014-01-30 Alcon Res Ltd Composições farmacêuticas aquosas que contêm complexos de borato-poliol
JP5303322B2 (ja) * 2009-03-13 2013-10-02 ピアス株式会社 皮膚外用組成物
TWI489997B (zh) 2009-06-19 2015-07-01 Alcon Res Ltd 含有硼酸－多元醇錯合物之水性藥學組成物
RU2012133444A (ru) * 2010-01-06 2014-02-20 Орф Лифтаекни Хф Способ, применения стабильного фактора роста растительного происхождения в уходе за кожей
EP2603232B1 (en) 2010-08-11 2019-09-25 Ironwood Pharmaceuticals, Inc. Stable formulations of linaclotide
JP5798356B2 (ja) * 2011-04-06 2015-10-21 一般財団法人化学及血清療法研究所 新規インフルエンザワクチン安定化剤
WO2014145016A2 (en) 2013-03-15 2014-09-18 Genentech, Inc. Il-22 polypeptides and il-22 fc fusion proteins and methods of use
US9283172B2 (en) 2013-12-13 2016-03-15 Growgene Biotech Inc. Use of stem cell conditioned medium to induce ZO-1 proteins expression for skin regeneration, repair and firming
KR101868966B1 (ko) * 2016-05-12 2018-06-19 주식회사 엔씨엘바이오 열 안정성을 증진시킨 사람 상피세포 성장인자의 조성물
CR20200327A (es) 2018-01-26 2020-11-05 Genentech Inc Proteínas de fusión fc il-22 y métodos de uso
CN112020365A (zh) 2018-01-26 2020-12-01 豪夫迈·罗氏有限公司 组合物和使用方法
KR20200123118A (ko) 2018-02-21 2020-10-28 제넨테크, 인크. IL-22 Fc 융합 단백질로 치료를 위한 투약

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US3887704A (en) * 1974-03-12 1975-06-03 Joseph Lichtenstein Aqueous zinc solutions for physiological use
FI78616C (fi) * 1982-02-05 1989-09-11 Novo Industri As Foerfarande foer framstaellning av en foer infusionsaendamaol avsedd stabiliserad insulinloesning, som har en foerhoejd zinkhalt.
DK113585D0 (da) * 1985-03-12 1985-03-12 Novo Industri As Nye peptider
HU194280B (en) * 1985-10-22 1988-01-28 Richter Gedeon Vegyeszet Process for producing new gonadoliberin analogues of high effectivity and pharmaceutical compositions containing them
US4816568A (en) * 1986-05-16 1989-03-28 International Minerals & Chemical Corp. Stabilization of growth hormones
FI882921A7 (fi) * 1986-10-20 1988-06-17 Novo Ind A/S Protamiinisinkki-insuliinivalmisteet.
US4717717A (en) * 1986-11-05 1988-01-05 Ethicon, Inc. Stabilized compositions containing epidermal growth factor
US4764592A (en) * 1987-04-23 1988-08-16 Eli Lilly And Company Crystalline human proinsulin and process for its production
DE3731255A1 (de) * 1987-09-17 1989-04-06 Boehringer Ingelheim Int Stabilisierung von therapeutisch wirksamen proteinen in pharmazeutischen zubereitungen
US5272063A (en) * 1988-11-22 1993-12-21 Syntex (U.S.A.) Inc. Process of making human nerve growth factor

Also Published As

Publication number Publication date
PT94037B (pt) 1996-11-29
AU5496890A (en) 1990-11-22
GR900100334A (en) 1991-10-10
ES2058799T3 (es) 1994-11-01
GR1000392B (el) 1992-06-30
KR900017580A (ko) 1990-12-19
CA2016659A1 (en) 1990-11-16
CA2016659C (en) 1996-12-10
EP0398619A2 (en) 1990-11-22
EP0398619A3 (en) 1991-04-03
JP2763815B2 (ja) 1998-06-11
DE69002795T2 (de) 1994-01-13
DK0398619T3 (da) 1993-10-04
DE69002795D1 (de) 1993-09-23
US5130298A (en) 1992-07-14
JPH0334992A (ja) 1991-02-14
EP0398619B1 (en) 1993-08-18
AU630952B2 (en) 1992-11-12

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Legal Events

Date Code Title Description
FG3A Patent granted, date of granting

Effective date: 19960829