PT96303A - Processo para a preparacao de novos derivados do acido piperidinocarboxilico com accao anestesica local e analgesica e de composicoes farmaceuticas que os contem - Google Patents

Processo para a preparacao de novos derivados do acido piperidinocarboxilico com accao anestesica local e analgesica e de composicoes farmaceuticas que os contem

Info

Publication number: PT96303A
Authority: PT; Portugal
Prior art keywords: acid; local; preparation; piperidinocarboxyl; pharmaceutical compositions
Prior art date: 1989-12-21

Application number

PT96303A

Other languages

English (en)

Other versions

PT96303B (pt

Inventor

Anna-Lena Ask

Rune Verner Sandberg

Original Assignee

Astra Ab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-12-21

Filing date

1990-12-20

Publication date

1991-09-30

1990-12-20 Application filed by Astra Ab filed Critical Astra Ab

1991-09-30 Publication of PT96303A publication Critical patent/PT96303A/pt

1998-07-31 Publication of PT96303B publication Critical patent/PT96303B/pt

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D211/62—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4
- C07D211/64—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4 having an aryl radical as the second substituent in position 4
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Pain & Pain Management (AREA)
Public Health (AREA)
Rheumatology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Hydrogenated Pyridines (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Cosmetics (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

PT96303A 1989-12-21 1990-12-20 Processo para a preparacao de novos derivados do acido piperidinocarboxilico com accao anestesica local e analgesica e de composicoes farmaceuticas que os contem PT96303B (pt)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
SE8904298A SE8904298D0 (sv)	1989-12-21	1989-12-21	New compounds

Publications (2)

Publication Number	Publication Date
PT96303A true PT96303A (pt)	1991-09-30
PT96303B PT96303B (pt)	1998-07-31

Family

ID=20377821

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PT96303A PT96303B (pt)	1989-12-21	1990-12-20	Processo para a preparacao de novos derivados do acido piperidinocarboxilico com accao anestesica local e analgesica e de composicoes farmaceuticas que os contem

Country Status (40)

Country	Link
US (2)	US5227389A (pt)
EP (1)	EP0506778B1 (pt)
JP (1)	JP2656152B2 (pt)
KR (1)	KR0179382B1 (pt)
CN (1)	CN1037841C (pt)
AT (1)	ATE138650T1 (pt)
AU (1)	AU647068B2 (pt)
BG (1)	BG60912B1 (pt)
BR (1)	BR1100379A (pt)
CA (1)	CA2069608C (pt)
CZ (1)	CZ278035B6 (pt)
DE (1)	DE69027221T2 (pt)
DK (1)	DK0506778T3 (pt)
DZ (1)	DZ1468A1 (pt)
EG (1)	EG19361A (pt)
ES (1)	ES2087280T3 (pt)
FI (1)	FI100881B (pt)
HK (1)	HK22997A (pt)
HR (1)	HRP920591B1 (pt)
HU (1)	HU213110B (pt)
IE (1)	IE74855B1 (pt)
IL (1)	IL96636A (pt)
IS (1)	IS1664B (pt)
LT (1)	LT4005B (pt)
LV (2)	LV10949B (pt)
NO (1)	NO178858C (pt)
NZ (1)	NZ236293A (pt)
PL (1)	PL163591B1 (pt)
PT (1)	PT96303B (pt)
RO (1)	RO112864B1 (pt)
RU (1)	RU2039043C1 (pt)
SA (1)	SA91110209B1 (pt)
SE (1)	SE8904298D0 (pt)
SG (1)	SG46413A1 (pt)
SI (1)	SI9012346B (pt)
SK (1)	SK278283B6 (pt)
UA (1)	UA26403A (pt)
WO (1)	WO1991009845A1 (pt)
YU (1)	YU48086B (pt)
ZA (1)	ZA909903B (pt)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP3916092B2 (ja) *	1993-09-17	2007-05-16	杏林製薬株式会社	イミダゾリジノン誘導体とその酸付加塩及び老年性痴呆症の治療薬
SE9400447D0 (sv) *	1994-02-11	1994-02-11	Astra Ab	New compounds
SE9404438D0 (sv) *	1994-12-21	1994-12-21	Astra Ab	New process
US5931809A (en)	1995-07-14	1999-08-03	Depotech Corporation	Epidural administration of therapeutic compounds with sustained rate of release
GB9600235D0 (en) *	1996-01-05	1996-03-06	Pfizer Ltd	Therapeutic agents
DE19642591A1 (de) *	1996-10-15	1998-04-16	Basf Ag	Neue Piperidin-Ketocarbonsäure-Derivate, deren Herstellung und Anwendung
TW548271B (en) *	1996-12-20	2003-08-21	Astra Pharma Inc	Novel piperidine derivatives having an exocyclic double bond with analgesic effects
SE9604786D0 (sv) *	1996-12-20	1996-12-20	Astra Pharma Inc	New compounds
RU2125878C1 (ru) *	1996-12-26	1999-02-10	Новокузнецкий научно-исследовательский химико-фармацевтический институт	Анальгетическое средство
RU2117481C1 (ru) *	1997-07-15	1998-08-20	Государственный научно-исследовательский институт органической химии и технологии	Анальгетическое средство и способ его приготовления
US7799337B2 (en)	1997-07-21	2010-09-21	Levin Bruce H	Method for directed intranasal administration of a composition
US20020102291A1 (en) *	1997-12-15	2002-08-01	Noven Pharmaceuticals, Inc.	Compositions and method for treatment of attention deficit disorder and attention deficit/hyperactivity disorder with methylphenidate
SE9803240D0 (sv) *	1998-09-24	1998-09-24	Diabact Ab	A pharmaceutical composition having a rapid action
SE9803239D0 (sv) *	1998-09-24	1998-09-24	Diabact Ab	Composition for the treatment of acute pain
CA2443672C (en) *	2001-04-12	2011-03-29	Pharmacopeia, Inc.	Aryl and biaryl piperidines used as mch antagonists
RU2203041C1 (ru) *	2001-12-27	2003-04-27	Закрытое акционерное общество "Брынцалов-А"	Спазмолитические таблетки бралангин
ATE496028T1 (de) *	2002-02-08	2011-02-15	Ono Pharmaceutical Co	Piperidinderivatverbindungen und arzneimittel, die diese verbindungen als wirkstoff enthalten
CN1744899A (zh) *	2002-12-13	2006-03-08	史密丝克莱恩比彻姆公司	作为ccr5拮抗剂的哌啶衍生物
US20100210633A1 (en) *	2006-10-12	2010-08-19	Epix Delaware, Inc.	Carboxamide compounds and their use
AU2008335135A1 (en)	2007-12-11	2009-06-18	Cytopathfinder, Inc.	Carboxamide compounds and their use as chemokine receptor agonists
US8473062B2 (en)	2008-05-01	2013-06-25	Autonomic Technologies, Inc.	Method and device for the treatment of headache
US8412336B2 (en)	2008-12-29	2013-04-02	Autonomic Technologies, Inc.	Integrated delivery and visualization tool for a neuromodulation system
US9320908B2 (en)	2009-01-15	2016-04-26	Autonomic Technologies, Inc.	Approval per use implanted neurostimulator
US8494641B2 (en)	2009-04-22	2013-07-23	Autonomic Technologies, Inc.	Implantable neurostimulator with integral hermetic electronic enclosure, circuit substrate, monolithic feed-through, lead assembly and anchoring mechanism
EP3914246A1 (en)	2019-01-22	2021-12-01	ICM (Institut du Cerveau et de la Moelle Épinière)	Local anesthetic for the treatment of neurological symptoms resulting from brain dysfunctions

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
SE96980C1 (pt)
US2486796A (en) *	1943-06-25	1949-11-01	Ciba Pharm Prod Inc	Esters of 1-alkyl-4-hydroxyphenylpiperidyl-4-ketones
US3334106A (en) *	1964-10-20	1967-08-01	Aldrich Chem Co Inc	N(aryl)n(hydrocarbyl)-omega-(4-phenyl-4-piperidinocarbonylheteroamine) alkanoamide
US3539580A (en) *	1967-06-26	1970-11-10	Janssen Pharm	4-aryl-4-aminoalkoxy-piperidines
CH498836A (de) *	1968-12-20	1970-11-15	Geigy Ag J R	Verfahren zur Herstellung von neuen Piperidinderivaten
US3737538A (en) *	1968-12-30	1973-06-05	Ciba Geigy Corp	Antitussive compositions and method with isonipecotic acid derivatives
FR2156470A2 (en) *	1971-10-21	1973-06-01	Synthelabo	1-(3,3-diphenyl-1-propyl)-4-aryl-piperidines - as analgesics spasmolytic and anti-tussive agents
ZA899436B (en) *	1988-12-12	1990-08-29	Ciba Geigy	Piperidine derivatives
US5100903A (en) *	1989-05-12	1992-03-31	Anaquest, Inc.	N-aryl-n-(1-substituted-3-alkoxy-4-piperidinyl)amides and pharmaceutical compositions and methods employing such compounds

1989
- 1989-12-21 SE SE8904298A patent/SE8904298D0/xx unknown
1990
- 1990-11-30 NZ NZ236293A patent/NZ236293A/xx unknown
- 1990-12-10 ZA ZA909903A patent/ZA909903B/xx unknown
- 1990-12-11 IL IL9663690A patent/IL96636A/en not_active IP Right Cessation
- 1990-12-12 SI SI9012346A patent/SI9012346B/sl not_active IP Right Cessation
- 1990-12-12 YU YU234690A patent/YU48086B/sh unknown
- 1990-12-12 DZ DZ900223A patent/DZ1468A1/xx active
- 1990-12-17 UA UA5052485A patent/UA26403A/uk unknown
- 1990-12-17 WO PCT/SE1990/000818 patent/WO1991009845A1/en not_active Ceased
- 1990-12-17 KR KR1019920701484A patent/KR0179382B1/ko not_active Expired - Fee Related
- 1990-12-17 JP JP3501896A patent/JP2656152B2/ja not_active Expired - Fee Related
- 1990-12-17 CA CA002069608A patent/CA2069608C/en not_active Expired - Fee Related
- 1990-12-17 SG SG1996004491A patent/SG46413A1/en unknown
- 1990-12-17 EP EP91901571A patent/EP0506778B1/en not_active Expired - Lifetime
- 1990-12-17 ES ES91901571T patent/ES2087280T3/es not_active Expired - Lifetime
- 1990-12-17 HU HU9202044A patent/HU213110B/hu unknown
- 1990-12-17 RO RO92-0832A patent/RO112864B1/ro unknown
- 1990-12-17 IE IE453490A patent/IE74855B1/en not_active IP Right Cessation
- 1990-12-17 IS IS3659A patent/IS1664B/is unknown
- 1990-12-17 AU AU69783/91A patent/AU647068B2/en not_active Ceased
- 1990-12-17 DK DK91901571.9T patent/DK0506778T3/da active
- 1990-12-17 DE DE69027221T patent/DE69027221T2/de not_active Expired - Fee Related
- 1990-12-17 AT AT91901571T patent/ATE138650T1/de not_active IP Right Cessation
- 1990-12-20 EG EG74690A patent/EG19361A/xx active
- 1990-12-20 PT PT96303A patent/PT96303B/pt active IP Right Grant
- 1990-12-21 SK SK6581-90A patent/SK278283B6/sk unknown
- 1990-12-21 PL PL90288409A patent/PL163591B1/pl not_active IP Right Cessation
- 1990-12-21 CZ CS906581A patent/CZ278035B6/cs not_active IP Right Cessation
- 1990-12-21 US US07/633,246 patent/US5227389A/en not_active Expired - Lifetime
- 1990-12-21 CN CN90106009A patent/CN1037841C/zh not_active Expired - Fee Related
1991
- 1991-01-09 SA SA91110209A patent/SA91110209B1/ar unknown
1992
- 1992-06-17 NO NO922380A patent/NO178858C/no unknown
- 1992-06-17 FI FI922806A patent/FI100881B/fi not_active IP Right Cessation
- 1992-06-19 RU SU925052485A patent/RU2039043C1/ru not_active IP Right Cessation
- 1992-06-19 BG BG96513A patent/BG60912B1/bg unknown
- 1992-09-29 HR HRP-2346/90A patent/HRP920591B1/xx not_active IP Right Cessation
1993
- 1993-07-12 US US08/090,416 patent/US5360805A/en not_active Expired - Lifetime
- 1993-08-27 LV LVP-93-1042A patent/LV10949B/lv unknown
- 1993-12-30 LT LTIP1731A patent/LT4005B/lt not_active IP Right Cessation
1996
- 1996-07-17 LV LV960262A patent/LV5766B4/xx unknown
1997
- 1997-02-27 HK HK22997A patent/HK22997A/en not_active IP Right Cessation
- 1997-04-30 BR BR1100379-0A patent/BR1100379A/pt active IP Right Grant

Also Published As

Publication number	Publication date
DK0506778T3 (da)	1996-10-07
EG19361A (en)	1994-12-30
EP0506778B1 (en)	1996-05-29
HU9202044D0 (en)	1992-09-28
LV10949A (lv)	1995-12-20
SK658190A3 (en)	1996-08-07
HU213110B (en)	1997-02-28
SK278283B6 (en)	1996-08-07
LTIP1731A (en)	1995-07-25
KR927003531A (ko)	1992-12-18
FI922806L (fi)	1992-06-17
JPH05502869A (ja)	1993-05-20
SA91110209B1 (ar)	2004-05-08
IE74855B1 (en)	1997-08-13
LT4005B (en)	1996-07-25
IL96636A (en)	1994-11-28
NO922380D0 (no)	1992-06-17
YU234690A (sh)	1993-10-20
CZ278035B6 (en)	1993-07-14
CZ658190A3 (en)	1993-01-13
DE69027221T2 (de)	1996-10-10
UA26403A (uk)	1999-08-30
LV5766B4 (lv)	1997-06-20
YU48086B (sh)	1997-01-08
RU2039043C1 (ru)	1995-07-09
SI9012346A (sl)	1998-08-31
FI922806A0 (fi)	1992-06-17
HRP920591A2 (en)	1997-08-31
SI9012346B (sl)	1999-08-31
BG96513A (bg)	1993-12-24
AU647068B2 (en)	1994-03-17
ATE138650T1 (de)	1996-06-15
NZ236293A (en)	1992-10-28
BR1100379A (pt)	1999-12-07
WO1991009845A1 (en)	1991-07-11
HRP920591B1 (en)	1998-12-31
BG60912B1 (bg)	1996-06-28
JP2656152B2 (ja)	1997-09-24
DZ1468A1 (fr)	2004-09-13
IS1664B (is)	1997-07-04
IL96636A0 (en)	1991-09-16
CA2069608C (en)	2001-07-10
PL288409A1 (en)	1991-12-02
SG46413A1 (en)	1998-02-20
CN1053605A (zh)	1991-08-07
HK22997A (en)	1997-02-27
US5227389A (en)	1993-07-13
LV5766A4 (lv)	1996-12-20
CN1037841C (zh)	1998-03-25
CA2069608A1 (en)	1991-06-22
PL163591B1 (pl)	1994-04-29
ES2087280T3 (es)	1996-07-16
PT96303B (pt)	1998-07-31
NO178858C (no)	1996-06-19
LV10949B (en)	1996-06-20
EP0506778A1 (en)	1992-10-07
NO922380L (no)	1992-06-17
NO178858B (no)	1996-03-11
SE8904298D0 (sv)	1989-12-21
RO112864B1 (ro)	1998-01-30
FI100881B (fi)	1998-03-13
DE69027221D1 (de)	1996-07-04
IE904534A1 (en)	1991-07-03
IS3659A7 (is)	1991-06-22
KR0179382B1 (ko)	1999-03-20
AU6978391A (en)	1991-07-24
HUT64518A (en)	1994-01-28
US5360805A (en)	1994-11-01
ZA909903B (en)	1991-08-28

Legal Events

Date	Code	Title	Description
1991-09-30	BB1A	Laying open of patent application	Effective date: 19910509
1998-07-31	FG3A	Patent granted, date of granting	Effective date: 19980408

Publication	Publication Date	Title
PT83647B (pt)	1989-05-31	Processo para a preparacao de novos derivados de benzimidazole com actividade farmacologica e de composicoes farmaceuticas que os contem
PT91053A (pt)	1990-02-08	Processo para a preparacao de derivados de acido difosfonico e de composicoes farmaceuticas que os contem
PT91158A (pt)	1990-02-08	Processo para a preparacao de novos estirenos e carboxamidas heterociclicos biciclicos e composicoes farmaceuticas que os contem
EA199800477A1 (ru)	1998-12-24	Производные хинолина
NO178858C (no)	1996-06-19	Analogifremgangsmåte for fremstilling av substituerte 4-fenyl-4-piperidinkarboksamider med både lokal anestetisk og analgetisk effekt
PT96394A (pt)	1991-10-15	Processo para a preparacao de novos derivados do acido a-nor-esteroide-3-carboxilico e de composicoes farmaceuticas que os contem
PT96304A (pt)	1991-09-30	Processo para a preparacao de novos derivados de cromano e de tiocromano e de composicoes farmaceuticas que os contem
BR9910921A (pt)	2001-03-06	Composto, processo para preparar o mesmo, formulação farmacêutica, uso de um composto, e, processo para a profilaxia e/ou tratamento de condições clìnicas associadas com a resistência à insulina
PT99055A (pt)	1992-08-31	Processo para a preparacao de novas aminas alquil-heterociclicas e de composicoes farmaceuticas que as contem
PT84704B (pt)	1989-11-30	Processo para a preparacao de derivados do acido tiolactam-n-acetico e de composicoes farmaceuticas que os contem
MX9205916A (es)	1993-06-01	Derivados de acido ciclohexanoacetico, proceso para su preparacion y composicion farmaceutica que los comprende
PT93160A (pt)	1990-08-31	Processo para a preparacao de benzenossulfonamidas e de composicoes farmaceuticas que as contem
ES8307494A1 (es)	1983-08-01	"un procedimiento para preparar una composicion farmaceutica que proporciona un efecto anti-inflamatorio y analgesico junto con un dano gastrico minimizado".
PT82512B (pt)	1988-03-03	Processo para a preparacao de derivados de quinolilglicinamidas com actividade psicotropica e de composicoes farmaceuticas que os contem
PT81893B (pt)	1988-07-01	Processo para a preparacao de derivados de labdano e de composicoes farmaceuticas que os contem
PT88335A (pt)	1989-06-30	Processo para a preparacao de derivados do acido 1,4-dihidro-4-oxo-3-quinolinocarboxilico e de composicoes farmaceuticas que os contem
PT90904A (pt)	1989-12-29	Processo para a preparacao de derivados de 3-oxo-propanonitrilo triciclicos e de composicoes farmaceuticas que os contem
PT81576B (pt)	1987-11-11	Processo para a preparacao de derivados de mercaptano e de composicoes faramceuticas que os contem
PT97286A (pt)	1992-01-31	Processo para a preparacao de novos derivados do 3-aminocromano e de composicoes farmaceuticas que os contem
PT937043E (pt)	2002-07-31	Novos derivados tetra-hidropiridinicos substituidos processo para a sua preparacao e as composicoes farmaceuticas que os contem
PT85100A (pt)	1988-07-01	Processo para a preparacao de novos tetra-hidro-benzotiazois e de composicoes farmaceuticas que os contem
PT94078A (pt)	1991-01-08	Processo para a preparacao de derivados de acido butenoico e de composicoes farmaceuticas que os contem
PT90337A (pt)	1989-11-10	Processo para a preparacao de derivados de 6-oxo--piridazina e de composicoes farmaceuticas que os contem
PT82175B (pt)	1988-07-29	Processo para preparacao de novos derivados de 3-piridilmetilnaftalina e de composicoes farmceuticas que os contem
PT84680B (pt)	1989-12-29	Processo para a preparacao de derivados de 1,5-benzotiazepina e de composicoes farmaceuticas que os contem