PT96788B - Processo de preparacao de compostos de ureia substituida e de composicoes farmaceuticas - Google Patents

Processo de preparacao de compostos de ureia substituida e de composicoes farmaceuticas Download PDF

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Publication number
PT96788B
PT96788B PT96788A PT9678891A PT96788B PT 96788 B PT96788 B PT 96788B PT 96788 A PT96788 A PT 96788A PT 9678891 A PT9678891 A PT 9678891A PT 96788 B PT96788 B PT 96788B
Authority
PT
Portugal
Prior art keywords
formula
compounds
compound
pharmaceutically acceptable
urea
Prior art date
Application number
PT96788A
Other languages
English (en)
Portuguese (pt)
Other versions
PT96788A (pt
Inventor
John Bondo Hansen
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Publication of PT96788A publication Critical patent/PT96788A/pt
Publication of PT96788B publication Critical patent/PT96788B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/14—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing 9-azabicyclo [3.3.1] nonane ring systems, e.g. granatane, 2-aza-adamantane; Cyclic acetals thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/06—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing isoquinuclidine ring systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Treating Waste Gases (AREA)
  • Peptides Or Proteins (AREA)
  • Cephalosporin Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
PT96788A 1990-02-16 1991-02-15 Processo de preparacao de compostos de ureia substituida e de composicoes farmaceuticas PT96788B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK040890A DK40890D0 (da) 1990-02-16 1990-02-16 Substituerede urinstofforbindelser, deres fremstilling og anvendelse

Publications (2)

Publication Number Publication Date
PT96788A PT96788A (pt) 1991-10-31
PT96788B true PT96788B (pt) 1998-07-31

Family

ID=8093190

Family Applications (1)

Application Number Title Priority Date Filing Date
PT96788A PT96788B (pt) 1990-02-16 1991-02-15 Processo de preparacao de compostos de ureia substituida e de composicoes farmaceuticas

Country Status (15)

Country Link
US (2) US5187164A (fr)
EP (1) EP0515537B1 (fr)
JP (1) JPH05504358A (fr)
AT (1) ATE156128T1 (fr)
AU (1) AU648066B2 (fr)
CA (1) CA2074803A1 (fr)
DE (1) DE69127072T2 (fr)
DK (1) DK40890D0 (fr)
FI (1) FI923475A0 (fr)
IE (1) IE910523A1 (fr)
IL (1) IL97429A (fr)
NZ (1) NZ237122A (fr)
PT (1) PT96788B (fr)
WO (1) WO1991012254A1 (fr)
ZA (1) ZA911103B (fr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5530008A (en) * 1989-04-21 1996-06-25 Sandoz Ltd. Use of 5-HT3 receptor antagonists in treating panic disorders or obsessive compulsive disorders
DK443489D0 (da) * 1989-09-08 1989-09-08 Ferrosan As Substituerede urinstofforbindelser, deres fremstilling og anvendelse
GB9214184D0 (en) * 1992-07-03 1992-08-12 Smithkline Beecham Plc Pharmaceuticals
US5663182A (en) * 1993-08-19 1997-09-02 Bymaster; Franklin Porter Antipsychotic method
US6953855B2 (en) * 1998-12-11 2005-10-11 Targacept, Inc. 3-substituted-2(arylalkyl)-1-azabicycloalkanes and methods of use thereof
WO2001095903A1 (fr) * 2000-06-15 2001-12-20 Respiratorius Ab Antagonistes du recepteur 5-ht3 destines au traitement de troubles englobant la constriction des voies aeriennes
AU2003303373B8 (en) * 2002-12-18 2010-06-10 Cytovia, Inc. 3,5-disubstituted-[1,2,4]-oxadiazoles and analogs as activators of caspases and inducers of apoptosis and the use thereof
DK1663978T3 (da) 2003-07-23 2008-04-07 Bayer Pharmaceuticals Corp Fluorsubstitueret omega-carboxyaryl-diphenylurinstof til behandling og forebyggelse af sygdomme og lidelser
SA08290475B1 (ar) 2007-08-02 2013-06-22 Targacept Inc (2s، 3r)-n-(2-((3-بيردينيل)ميثيل)-1-آزا بيسيكلو[2، 2، 2]أوكت-3-يل)بنزو فيوران-2-كربوكساميد، وصور أملاحه الجديدة وطرق استخدامه
TW201031664A (en) 2009-01-26 2010-09-01 Targacept Inc Preparation and therapeutic applications of (2S,3R)-N-2-((3-pyridinyl)methyl)-1-azabicyclo[2.2.2]oct-3-yl)-3,5-difluorobenzamide
WO2014051055A1 (fr) * 2012-09-28 2014-04-03 東レ株式会社 Dérivés de quinuclidine urée et utilisation médicale de ceux-ci
US9724340B2 (en) 2015-07-31 2017-08-08 Attenua, Inc. Antitussive compositions and methods

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3917615A (en) * 1974-04-01 1975-11-04 Searle & Co 1,1-Diaryl-1-oxadiazol-alkylamines
US4003904A (en) * 1974-04-01 1977-01-18 G. D. Searle & Co. Anti-diarrheal oxadiazoles
CH614709A5 (fr) * 1975-09-25 1979-12-14 Ciba Geigy Ag
US4012393A (en) * 1976-03-22 1977-03-15 G. D. Searle & Co. 2-[5-(CYCLIC AMINO) ETHYL-10,11-DIHYDRO-5H-dibenzo[a,d]-cyclohepten-5- yl]-5
EP0235878A3 (fr) * 1986-01-16 1989-06-14 Beecham Group Plc Nouveaux composés
DE3785507T2 (de) * 1986-07-31 1993-07-29 Beecham Group Plc Azabicyclische verbindungen, verfahren zu ihrer herstellung und ihre pharmazeutische verwendung.
IE63906B1 (en) * 1987-11-13 1995-06-14 Novo Nordisk As Azabicyclic compounds and their preparation and use
IE62231B1 (en) * 1987-12-24 1995-01-11 Wyeth John & Brother Ltd Heterocyclic compounds
US4863921A (en) * 1988-04-27 1989-09-05 Rorer Pharmaceutical Corporation Dibenzofurancarboxamides and their pharmaceutical compositions and methods
DK443489D0 (da) * 1989-09-08 1989-09-08 Ferrosan As Substituerede urinstofforbindelser, deres fremstilling og anvendelse

Also Published As

Publication number Publication date
US5187164A (en) 1993-02-16
EP0515537B1 (fr) 1997-07-30
US5290795A (en) 1994-03-01
DK40890D0 (da) 1990-02-16
AU648066B2 (en) 1994-04-14
CA2074803A1 (fr) 1991-08-17
IE910523A1 (en) 1991-08-28
FI923475L (fi) 1992-07-31
PT96788A (pt) 1991-10-31
IL97429A0 (en) 1992-06-21
AU7340991A (en) 1991-09-03
NZ237122A (en) 1993-02-25
ZA911103B (en) 1991-11-27
ATE156128T1 (de) 1997-08-15
DE69127072D1 (de) 1997-09-04
IL97429A (en) 1996-01-31
FI923475A7 (fi) 1992-07-31
WO1991012254A1 (fr) 1991-08-22
DE69127072T2 (de) 1998-01-22
FI923475A0 (fi) 1992-07-31
JPH05504358A (ja) 1993-07-08
EP0515537A1 (fr) 1992-12-02

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BB1A Laying open of patent application

Effective date: 19910702

FG3A Patent granted, date of granting

Effective date: 19980407

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Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 19991031