ZA911103B - Substituted urea compounds and their preparation and use - Google Patents

Substituted urea compounds and their preparation and use

Info

Publication number: ZA911103B
Authority: ZA; South Africa
Prior art keywords: chemical structure; urea compounds; substituted urea; preparation; alkyl
Prior art date: 1990-02-16

Application number

ZA911103A

Other languages

English (en)

Inventor

John Bondo Hansen

Bondo Hansen John

Original Assignee

Novo Nordisk As

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-02-16

Filing date

1991-02-14

Publication date

1991-11-27

1991-02-14 Application filed by Novo Nordisk As filed Critical Novo Nordisk As

1991-11-27 Publication of ZA911103B publication Critical patent/ZA911103B/xx

Links

150000003672 ureas Chemical class 0.000 title abstract 2
239000000126 substance Substances 0.000 abstract 5
125000000217 alkyl group Chemical group 0.000 abstract 2
125000004191 (C1-C6) alkoxy group Chemical group 0.000 abstract 1
125000006700 (C1-C6) alkylthio group Chemical group 0.000 abstract 1
125000004209 (C1-C8) alkyl group Chemical group 0.000 abstract 1
125000005913 (C3-C6) cycloalkyl group Chemical group 0.000 abstract 1
125000006272 (C3-C7) cycloalkyl group Chemical group 0.000 abstract 1
125000004648 C2-C8 alkenyl group Chemical group 0.000 abstract 1
125000004649 C2-C8 alkynyl group Chemical group 0.000 abstract 1
150000001204 N-oxides Chemical class 0.000 abstract 1
208000028017 Psychotic disease Diseases 0.000 abstract 1
206010047700 Vomiting Diseases 0.000 abstract 1
125000003282 alkyl amino group Chemical group 0.000 abstract 1
125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
WCPAKWJPBJAGKN-UHFFFAOYSA-N oxadiazole Chemical group C1=CON=N1 WCPAKWJPBJAGKN-UHFFFAOYSA-N 0.000 abstract 1
239000000825 pharmaceutical preparation Substances 0.000 abstract 1
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
- C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/14—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing 9-azabicyclo [3.3.1] nonane ring systems, e.g. granatane, 2-aza-adamantane; Cyclic acetals thereof
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
- C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
- C07D453/06—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing isoquinuclidine ring systems

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Public Health (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Treating Waste Gases (AREA)
Cephalosporin Compounds (AREA)
Solid-Sorbent Or Filter-Aiding Compositions (AREA)
Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
Peptides Or Proteins (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Plural Heterocyclic Compounds (AREA)

ZA911103A 1990-02-16 1991-02-14 Substituted urea compounds and their preparation and use ZA911103B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DK040890A DK40890D0 (da)	1990-02-16	1990-02-16	Substituerede urinstofforbindelser, deres fremstilling og anvendelse

Publications (1)

Publication Number	Publication Date
ZA911103B true ZA911103B (en)	1991-11-27

Family

ID=8093190

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA911103A ZA911103B (en)	1990-02-16	1991-02-14	Substituted urea compounds and their preparation and use

Country Status (15)

Country	Link
US (2)	US5187164A (fr)
EP (1)	EP0515537B1 (fr)
JP (1)	JPH05504358A (fr)
AT (1)	ATE156128T1 (fr)
AU (1)	AU648066B2 (fr)
CA (1)	CA2074803A1 (fr)
DE (1)	DE69127072T2 (fr)
DK (1)	DK40890D0 (fr)
FI (1)	FI923475A7 (fr)
IE (1)	IE910523A1 (fr)
IL (1)	IL97429A (fr)
NZ (1)	NZ237122A (fr)
PT (1)	PT96788B (fr)
WO (1)	WO1991012254A1 (fr)
ZA (1)	ZA911103B (fr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5530008A (en) *	1989-04-21	1996-06-25	Sandoz Ltd.	Use of 5-HT3 receptor antagonists in treating panic disorders or obsessive compulsive disorders
DK443489D0 (da) *	1989-09-08	1989-09-08	Ferrosan As	Substituerede urinstofforbindelser, deres fremstilling og anvendelse
GB9214184D0 (en) *	1992-07-03	1992-08-12	Smithkline Beecham Plc	Pharmaceuticals
US5663182A (en) *	1993-08-19	1997-09-02	Bymaster; Franklin Porter	Antipsychotic method
US6953855B2 (en)	1998-12-11	2005-10-11	Targacept, Inc.	3-substituted-2(arylalkyl)-1-azabicycloalkanes and methods of use thereof
AU2001225664A1 (en) *	2000-06-15	2001-12-24	Respiratorius Ab	5-ht3 receptor antagonists for treatment of disorders involving airway constriction
CN100364531C (zh) *	2002-12-18	2008-01-30	西托维亚公司	3,5－二取代－[1,2,4]－二唑及类似物和其用途
EP1663978B1 (fr)	2003-07-23	2007-11-28	Bayer Pharmaceuticals Corporation	Omega-carboxyaryldiphenyluree fluoro-subtituee pour le traitement et la prevention de maladies et d'etats pathologiques
SA08290475B1 (ar)	2007-08-02	2013-06-22	Targacept Inc	(2s، 3r)-n-(2-((3-بيردينيل)ميثيل)-1-آزا بيسيكلو[2، 2، 2]أوكت-3-يل)بنزو فيوران-2-كربوكساميد، وصور أملاحه الجديدة وطرق استخدامه
TW201031664A (en)	2009-01-26	2010-09-01	Targacept Inc	Preparation and therapeutic applications of (2S,3R)-N-2-((3-pyridinyl)methyl)-1-azabicyclo[2.2.2]oct-3-yl)-3,5-difluorobenzamide
JPWO2014051055A1 (ja) *	2012-09-28	2016-08-22	東レ株式会社	キヌクリジンウレア誘導体及びその医薬用途
US9724340B2 (en)	2015-07-31	2017-08-08	Attenua, Inc.	Antitussive compositions and methods

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4003904A (en) *	1974-04-01	1977-01-18	G. D. Searle & Co.	Anti-diarrheal oxadiazoles
US3917615A (en) *	1974-04-01	1975-11-04	Searle & Co	1,1-Diaryl-1-oxadiazol-alkylamines
CH614709A5 (fr) *	1975-09-25	1979-12-14	Ciba Geigy Ag
US4012393A (en) *	1976-03-22	1977-03-15	G. D. Searle & Co.	2-[5-(CYCLIC AMINO) ETHYL-10,11-DIHYDRO-5H-dibenzo[a,d]-cyclohepten-5- yl]-5
EP0235878A3 (fr) *	1986-01-16	1989-06-14	Beecham Group Plc	Nouveaux composés
DE3785507T2 (de) *	1986-07-31	1993-07-29	Beecham Group Plc	Azabicyclische verbindungen, verfahren zu ihrer herstellung und ihre pharmazeutische verwendung.
IL88156A (en) *	1987-11-13	1997-02-18	Novo Nordisk As	Azacyclic compounds their preparation and pharmaceutical compositions containing them
AU611976B2 (en) *	1987-12-24	1991-06-27	John Wyeth & Brother Limited	Aroyl urea and carbamic acid derivatives of azabicyclo compounds
US4863921A (en) *	1988-04-27	1989-09-05	Rorer Pharmaceutical Corporation	Dibenzofurancarboxamides and their pharmaceutical compositions and methods
DK443489D0 (da) *	1989-09-08	1989-09-08	Ferrosan As	Substituerede urinstofforbindelser, deres fremstilling og anvendelse

1990
- 1990-02-16 DK DK040890A patent/DK40890D0/da not_active Application Discontinuation
1991
- 1991-02-04 US US07/650,143 patent/US5187164A/en not_active Expired - Fee Related
- 1991-02-14 NZ NZ237122A patent/NZ237122A/xx unknown
- 1991-02-14 ZA ZA911103A patent/ZA911103B/xx unknown
- 1991-02-15 JP JP3504586A patent/JPH05504358A/ja active Pending
- 1991-02-15 AT AT91905032T patent/ATE156128T1/de not_active IP Right Cessation
- 1991-02-15 AU AU73409/91A patent/AU648066B2/en not_active Ceased
- 1991-02-15 FI FI923475A patent/FI923475A7/fi not_active Application Discontinuation
- 1991-02-15 DE DE69127072T patent/DE69127072T2/de not_active Expired - Fee Related
- 1991-02-15 IE IE052391A patent/IE910523A1/en unknown
- 1991-02-15 EP EP91905032A patent/EP0515537B1/fr not_active Expired - Lifetime
- 1991-02-15 CA CA002074803A patent/CA2074803A1/fr not_active Abandoned
- 1991-02-15 WO PCT/DK1991/000044 patent/WO1991012254A1/fr not_active Ceased
- 1991-02-15 PT PT96788A patent/PT96788B/pt not_active IP Right Cessation
- 1991-03-05 IL IL9742991A patent/IL97429A/en not_active IP Right Cessation
1992
- 1992-08-17 US US07/931,229 patent/US5290795A/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
DE69127072D1 (de)	1997-09-04
IL97429A0 (en)	1992-06-21
US5187164A (en)	1993-02-16
JPH05504358A (ja)	1993-07-08
FI923475L (fi)	1992-07-31
AU648066B2 (en)	1994-04-14
DE69127072T2 (de)	1998-01-22
FI923475A0 (fi)	1992-07-31
AU7340991A (en)	1991-09-03
IL97429A (en)	1996-01-31
IE910523A1 (en)	1991-08-28
ATE156128T1 (de)	1997-08-15
PT96788B (pt)	1998-07-31
EP0515537B1 (fr)	1997-07-30
US5290795A (en)	1994-03-01
PT96788A (pt)	1991-10-31
FI923475A7 (fi)	1992-07-31
NZ237122A (en)	1993-02-25
DK40890D0 (da)	1990-02-16
EP0515537A1 (fr)	1992-12-02
WO1991012254A1 (fr)	1991-08-22
CA2074803A1 (fr)	1991-08-17

Publication	Publication Date	Title
HU9200776D0 (en)	1992-08-28	Substituted urea compounds and their preparation and use
YU115688A (en)	1988-10-31	Process for obtaining derivatives of imidazole as calcium independent camp inhibtors of phosphodiestheraze
EP0279512A3 (fr)	1992-09-16	Emploi de certains antagonistes du récépteur 5-HT3 pour le traitement des douleurs viscérales
GR3033020T3 (en)	2000-08-31	Amide and urea derivatives having anti-hypercholesteremic activity, their preparation and their therapeutic uses.
AU637695B2 (en)	1993-06-03	Therapeutic agents
ZA911103B (en)	1991-11-27	Substituted urea compounds and their preparation and use
AU534786B2 (en)	1984-02-16	4-phenoxypiperidines
CS743389A3 (en)	1992-03-18	Amino(methyl)phenyl derivatives, process for their preparation and use
IE894039L (en)	1990-07-02	Therapeutic agents
NO923194L (no)	1992-08-14	Substituerte urea-forbindelser, deres fremstilling og anvendelse