PT98634A - Processo para a preparacao de derivados de pirimidina substiuidos - Google Patents

Processo para a preparacao de derivados de pirimidina substiuidos

Info

Publication number
PT98634A
PT98634A PT98634A PT9863491A PT98634A PT 98634 A PT98634 A PT 98634A PT 98634 A PT98634 A PT 98634A PT 9863491 A PT9863491 A PT 9863491A PT 98634 A PT98634 A PT 98634A
Authority
PT
Portugal
Prior art keywords
preparation
pyrimidine derivatives
substituted pyrimidine
sorbitol
reagents
Prior art date
Application number
PT98634A
Other languages
English (en)
Other versions
PT98634B (pt
Inventor
Karl Geisen
Roland Utz
Hildegard Nimmesgern
Hans-Jochen Lang
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of PT98634A publication Critical patent/PT98634A/pt
Publication of PT98634B publication Critical patent/PT98634B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32—One oxygen, sulfur or nitrogen atom
    • C07D239/42—One nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
    • C12Q1/32—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase involving dehydrogenase

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Emergency Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Endocrinology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Luminescent Compositions (AREA)
PT98634A 1990-08-10 1991-08-09 Processo para a preparacao de derivados de pirimidina substiuidos PT98634B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4025387A DE4025387A1 (de) 1990-08-10 1990-08-10 Substituierte pyrimidin-derivate, verfahren zu ihrer herstellung und ihre verwendung als reagenzien

Publications (2)

Publication Number Publication Date
PT98634A true PT98634A (pt) 1993-09-30
PT98634B PT98634B (pt) 1999-01-29

Family

ID=6412013

Family Applications (1)

Application Number Title Priority Date Filing Date
PT98634A PT98634B (pt) 1990-08-10 1991-08-09 Processo para a preparacao de derivados de pirimidina substiuidos

Country Status (16)

Country Link
US (1) US5215990A (pt)
EP (1) EP0470616B1 (pt)
JP (1) JP3094535B2 (pt)
KR (1) KR100191385B1 (pt)
AT (1) ATE149032T1 (pt)
AU (1) AU641797B2 (pt)
CA (1) CA2048842C (pt)
DE (2) DE4025387A1 (pt)
DK (1) DK0470616T3 (pt)
ES (1) ES2097774T3 (pt)
GR (1) GR3022976T3 (pt)
IE (1) IE912828A1 (pt)
IL (1) IL99134A (pt)
NZ (1) NZ239310A (pt)
PT (1) PT98634B (pt)
ZA (1) ZA916290B (pt)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994007867A1 (en) * 1992-09-28 1994-04-14 Pfizer Inc. Substituted pyrimidines for control of diabetic complications
EP0791355B1 (en) 1996-02-29 2002-04-17 Pfizer Inc. Method of reducing tissue damage associated with ischemia
JPH09301868A (ja) * 1996-05-10 1997-11-25 Senju Pharmaceut Co Ltd 抗白内障剤
DE19710435A1 (de) * 1997-03-13 1998-09-17 Hoechst Ag Verwendung von Pyrimidinderivaten zur Prävention von Krebs allein oder in Kombination mit anderen therapeutischen Maßnahmen
ATE264311T1 (de) * 1999-04-01 2004-04-15 Pfizer Prod Inc Verbindungen zur behandlung und vorsorge bei diabetes
PL350884A1 (en) * 1999-04-01 2003-02-10 Pfizer Prod Inc Aminopyrimidines as sorbitol dehydrogenase inhibitors
EP1247809A3 (en) 2001-03-30 2003-12-17 Pfizer Products Inc. Triazine compounds useful as sorbitol dehydrogenase inhibitors
AU2003245669A1 (en) * 2002-06-21 2004-01-06 Cellular Genomics, Inc. Certain aromatic monocycles as kinase modulators
AU2003249369A1 (en) * 2002-06-21 2004-01-06 Cellular Genomics, Inc. Certain amino-substituted monocycles as kinase modulators
RU2395503C2 (ru) 2004-05-19 2010-07-27 Зольвай Фармасьютиклз Гмбх Лекарственные средства, содержащие n-сульфамоил-n'-арилпиперазины, предназначенные для профилактики или лечения ожирения и связанных с ним состояний
US20050261292A1 (en) * 2004-05-19 2005-11-24 Solvay Pharmaceuticals Gmbh Pharmaceutical composition containing N-sulfamoyl-N'-arylpiperazines for the treatment or inhibition of obesity and related conditions
CN115124475B (zh) * 2022-07-11 2023-11-10 贵阳学院 一种嘧啶衍生物及其制备方法和用途

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2362276A (en) * 1942-03-31 1944-11-07 American Cyanamid Co Beneficiation of acidic minerals
US2973362A (en) * 1959-07-24 1961-02-28 Schorsch Gerald Method of preparing monosubstituted piperazines
US3190883A (en) * 1962-10-05 1965-06-22 Geschickter Fund Med Res Aminoalkanol derivatives of piperazines
US3296261A (en) * 1965-03-09 1967-01-03 Bristol Myers Co 6-hydroxy-pyrimidine-5-acetamides
DK8600939A (pt) * 1985-03-05 1986-09-06
DE3905364A1 (de) * 1989-02-22 1990-08-23 Hoechst Ag Substituierte pyrimidin-derivate, verfahren zu ihrer herstellung und ihre verwendung als tool

Also Published As

Publication number Publication date
ES2097774T3 (es) 1997-04-16
EP0470616B1 (de) 1997-02-19
DE59108549D1 (de) 1997-03-27
KR100191385B1 (ko) 1999-06-15
IL99134A0 (en) 1992-07-15
AU8256191A (en) 1992-02-13
EP0470616A2 (de) 1992-02-12
DK0470616T3 (da) 1997-08-25
DE4025387A1 (de) 1992-02-13
IE912828A1 (en) 1992-02-12
NZ239310A (en) 1993-07-27
ZA916290B (en) 1992-04-29
AU641797B2 (en) 1993-09-30
US5215990A (en) 1993-06-01
IL99134A (en) 1995-08-31
JPH04230669A (ja) 1992-08-19
PT98634B (pt) 1999-01-29
KR920004381A (ko) 1992-03-27
EP0470616A3 (en) 1992-03-25
JP3094535B2 (ja) 2000-10-03
ATE149032T1 (de) 1997-03-15
CA2048842A1 (en) 1992-02-11
GR3022976T3 (en) 1997-06-30
CA2048842C (en) 2002-04-09

Similar Documents

Publication Publication Date Title
PT93224A (pt) Processo para a preparacao de derivados substituidos de pirimidina
ES2097774T3 (es) Derivados de pirimidina sustituidos, procedimiento para su preparacion y su utilizacion como reactivos.
NO20022532D0 (no) Fremgangsmåte for fremstilling av nukleinsyrer fra en miljöpröve, de således oppnådde nukleinsyrer samt deres anvendelseved syntese av nye forbindelser
ATE215371T1 (de) Naphthyl substituierte benzimidazolderivate als antikoagulantien
PT97890A (pt) Processo para a preparacao de ftalidas substituidas e de ftalidas heterociclicas
NO962386D0 (no) Heterocykliske ring-kondenserte pyrimidin-derivater
BR9401617A (pt) Derivados de oxazabiciclo e seu uso como agonistas receptores de 5-ht4 e processo para sua preparação
ATE116000T1 (de) Lichtaktivierte acylenzyme.
SE7910376L (sv) Kinazolinonderivat
NO890689D0 (no) Spesielle kjemiluminiscerende akridinderivater og deres anvendelse i luminiscens-immunoanalyser.
BR8207050A (pt) Composicao herbicidas a base de derivados de ureia,e,processo para preparacao destes derivados
ES2080336T3 (es) Derivados de metilpiperazinoazepina, su preparacion y su utilizacion.
BR9101976A (pt) Derivado de pirimidina,processo para sua producao e composicao herbicida
DE59007185D1 (de) Substituierte 1.2.3.4-Oxatriazolium-5-olate, Verfahren zu ihrer Herstellung und ihre Verwendung.
DE69004844D1 (de) Pyrimidin-Derivate.
DE59007135D1 (de) Azofarbstoffe und Zwischenprodukte zu deren Herstellung.
NO20002154D0 (no) Nye heterocykliske substituerte alfa-hydroksykarboksylsyre- derivater
PT1007498E (pt) Processo para o fabrico de 2-halogenoindano-1-onas
ES2021994A6 (es) Tope para vehiculos sobre rieles o similares.
BR9301103A (pt) Processo de diagnóstico rápido de campo para anemia infecciosa equina, através de obtenção de antígenos obtidos em cultura celular adsorvidos em poliestireno u nitrocelulose

Legal Events

Date Code Title Description
BB1A Laying open of patent application

Effective date: 19930507

FG3A Patent granted, date of granting

Effective date: 19981020