RO69617A - Procede pour preparer des 2-tetrahydrofurfuril-6,7-benzomorphanes - Google Patents

Procede pour preparer des 2-tetrahydrofurfuril-6,7-benzomorphanes

Info

Publication number
RO69617A
RO69617A RO7589653A RO8965375A RO69617A RO 69617 A RO69617 A RO 69617A RO 7589653 A RO7589653 A RO 7589653A RO 8965375 A RO8965375 A RO 8965375A RO 69617 A RO69617 A RO 69617A
Authority
RO
Romania
Prior art keywords
benzomorphans
furfuryl
tetrahydro
preparation
Prior art date
Application number
RO7589653A
Other languages
English (en)
Romanian (ro)
Inventor
Herbert Merz
Adolf Langbein
Gerhard Walther
Klaus Steckhaus
Original Assignee
C.H.Boehringer Sohn,De
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by C.H.Boehringer Sohn,De filed Critical C.H.Boehringer Sohn,De
Publication of RO69617A publication Critical patent/RO69617A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/22—Bridged ring systems
    • C07D221/26—Benzomorphans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
RO7589653A 1974-03-09 1975-03-07 Procede pour preparer des 2-tetrahydrofurfuril-6,7-benzomorphanes RO69617A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2411382A DE2411382C3 (de) 1974-03-09 1974-03-09 2-Tetrahydrofurfuryl-6,7-benzomorphane, Verfahren zur Herstellung und deren Verwendung

Publications (1)

Publication Number Publication Date
RO69617A true RO69617A (fr) 1980-08-15

Family

ID=5909593

Family Applications (2)

Application Number Title Priority Date Filing Date
RO7589654A RO70051A (fr) 1974-03-09 1975-03-07 Procede pour la preparation des 2-tetra-hydrofurfurile-6,7-benzomorphanes
RO7589653A RO69617A (fr) 1974-03-09 1975-03-07 Procede pour preparer des 2-tetrahydrofurfuril-6,7-benzomorphanes

Family Applications Before (1)

Application Number Title Priority Date Filing Date
RO7589654A RO70051A (fr) 1974-03-09 1975-03-07 Procede pour la preparation des 2-tetra-hydrofurfurile-6,7-benzomorphanes

Country Status (25)

Country Link
JP (1) JPS5827275B2 (fr)
AT (1) AT344332B (fr)
BE (1) BE826440A (fr)
BG (3) BG24814A4 (fr)
CA (1) CA1049511A (fr)
CH (8) CH612425A5 (fr)
CS (1) CS188221B2 (fr)
DD (1) DD119236A5 (fr)
DE (1) DE2411382C3 (fr)
DK (1) DK137188C (fr)
ES (6) ES440345A1 (fr)
FI (1) FI63571C (fr)
FR (1) FR2262984B1 (fr)
GB (1) GB1496418A (fr)
HU (1) HU177408B (fr)
IE (1) IE40945B1 (fr)
IL (1) IL46760A (fr)
NL (1) NL7502724A (fr)
NO (1) NO141800C (fr)
PH (1) PH14127A (fr)
PL (3) PL93699B1 (fr)
RO (2) RO70051A (fr)
SE (1) SE421919B (fr)
SU (3) SU577982A3 (fr)
ZA (1) ZA751394B (fr)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2716687A1 (de) * 1977-04-15 1978-10-19 Boehringer Sohn Ingelheim 2'-hydroxy-2-(5-isoxazolylmethyl)-6,7benzomorphane, deren saeureadditionssalze und diese enthaltende arzneimittel
DE2828039A1 (de) * 1978-06-26 1980-01-10 Boehringer Sohn Ingelheim 2-(2-alkoxyethyl)-2'-hydroxy-6,7-benzomorphane deren saeureadditionssalze diese enthaltende arzneimittel und verfahren zu deren herstellung
NZ303251A (en) * 1995-03-10 2000-10-27 Photocure Asa Use of esters of 5-aminolevulinic acid as photosensitising agents in photochemotherapy
US6492420B2 (en) 1995-03-10 2002-12-10 Photocure As Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy
US6992107B1 (en) 1995-03-10 2006-01-31 Photocure Asa Esters of 5-aminolevulinic acid and their use as photosensitizing compounds in photochemotherapy
US7530461B2 (en) 1995-03-10 2009-05-12 Photocure Asa Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy
GB0018528D0 (en) 2000-07-27 2000-09-13 Photocure Asa Compounds
US6723750B2 (en) 2002-03-15 2004-04-20 Allergan, Inc. Photodynamic therapy for pre-melanomas
US8329897B2 (en) 2007-07-26 2012-12-11 Vitae Pharmaceuticals, Inc. Synthesis of inhibitors of 11β-hydroxysteroid dehydrogenase type 1
EP2220048B1 (fr) 2007-11-16 2017-01-25 Boehringer Ingelheim International GmbH Derives aryl et heteroarylcarbonyle de benzomorphanes et de structures d'echafaudage associees, medicaments les contenant et leur utilisation
JP5490014B2 (ja) 2007-12-11 2014-05-14 ヴァイティー ファーマシューティカルズ，インコーポレイテッド １１β−ヒドロキシステロイドデヒドロゲナーゼ１型の環状尿素阻害剤
TW200934490A (en) 2008-01-07 2009-08-16 Vitae Pharmaceuticals Inc Lactam inhibitors of 11 &abgr;-hydroxysteroid dehydrogenase 1
EP2252601B1 (fr) 2008-01-24 2012-12-19 Vitae Pharmaceuticals, Inc. Carbazate cyclique et inhibiteurs du type semi-carbazide de la 11 -hydroxystéroïde déshydrogénase 1
EP2254872A2 (fr) 2008-02-15 2010-12-01 Vitae Pharmaceuticals, Inc. Inhibiteurs de 11beta-hydroxystéroïde deshydrogénase 1
JP5538365B2 (ja) 2008-05-01 2014-07-02 ヴァイティー ファーマシューティカルズ，インコーポレイテッド １１β−ヒドロキシステロイドデヒドロゲナーゼ１の環状阻害剤
CL2009001058A1 (es) 2008-05-01 2010-09-10 Vitae Pharmaceuticals Inc Compuestos derivados de oxazinas sustituidas, inhibidores de la 11b-hidroxiesteroide deshidrogenasa de tipo-1; composicion farmaceutica; y uso del compuesto para inhibir la actividad de 11b-hsd1, como en el tratamiento de la diabetes, dislipidemia, hipertension, obesidad, cancer, glaucoma, entre otras.
CA2722427A1 (fr) 2008-05-01 2009-11-05 Vitae Pharmaceuticals, Inc. Inhibiteurs cycliques de la 11-beta-hydroxysteroide dehydrogenase 1
WO2009138386A2 (fr) 2008-05-13 2009-11-19 Boehringer Ingelheim International Gmbh Dérivés d’acide carboxylique alicyclique de benzomorphanes et échafaudages afférents, médicaments contenant ces composés, et utilisation de ceux-ci
JP5777030B2 (ja) 2008-07-25 2015-09-09 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング １１β−ヒドロキシステロイドデヒドロゲナーゼ１の阻害剤
RU2539979C2 (ru) 2008-07-25 2015-01-27 Вайтаи Фармасьютиклз, Инк. Циклические ингибиторы 11бета-гидроксистероид-дегидрогеназы 1
MA33216B1 (fr) 2009-04-30 2012-04-02 Boehringer Ingelheim Int Inhibiteurs cycliques de la 11béta-hydroxysteroïde déshydrogénase 1
EP2440537A1 (fr) 2009-06-11 2012-04-18 Vitae Pharmaceuticals, Inc. Inhibiteurs cycliques de la 11-bêta-hydroxystéroïde déshydrogénase 1 basée sur la structure 1,3-oxazinan-2-one
TWI531571B (zh) 2009-11-06 2016-05-01 維它藥物公司 六氫茚并吡啶及八氫苯并喹啉之芳基－及雜芳基羰基衍生物
EP2582698B1 (fr) 2010-06-16 2016-09-14 Vitae Pharmaceuticals, Inc. Hétérocycles à 5, 6 et 7 chaînons substitués, médicaments contenant ces composés et leur utilisation
TWI537258B (zh) 2010-11-05 2016-06-11 百靈佳殷格翰國際股份有限公司 六氫茚并吡啶及八氫苯并喹啉之芳基－及雜環芳基羰基衍生物
JP2014524438A (ja) 2011-08-17 2014-09-22 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング インデノピリジン誘導体

Also Published As

Publication number Publication date
FI63571C (fi) 1983-07-11
DE2411382B2 (de) 1979-01-18
ATA153875A (de) 1977-11-15
JPS50123675A (fr) 1975-09-29
CH622017A5 (en) 1981-03-13
RO70051A (fr) 1980-12-30
CH620439A5 (en) 1980-11-28
BG24813A4 (bg) 1978-05-12
HU177408B (en) 1981-10-28
AU7894275A (en) 1976-09-16
CA1049511A (fr) 1979-02-27
CH622014A5 (en) 1981-03-13
GB1496418A (en) 1977-12-30
DE2411382A1 (de) 1975-09-18
DD119236A5 (fr) 1976-04-12
CS188221B2 (en) 1979-02-28
ES440348A1 (es) 1977-06-01
IL46760A (en) 1978-12-17
SU577982A3 (ru) 1977-10-25
IE40945B1 (en) 1979-09-12
ES440350A1 (es) 1977-03-16
ES440345A1 (es) 1977-03-01
FR2262984B1 (fr) 1978-07-28
CH620440A5 (en) 1980-11-28
FI63571B (fi) 1983-03-31
ES440346A1 (es) 1977-03-01
BE826440A (fr) 1975-09-08
CH620681A5 (en) 1980-12-15
SU588916A3 (ru) 1978-01-15
IE40945L (en) 1975-09-09
PL93699B1 (fr) 1977-06-30
PL93700B1 (fr) 1977-06-30
BG24814A4 (bg) 1978-05-12
PL93499B1 (fr) 1977-05-30
FI750652A7 (fr) 1975-09-10
ZA751394B (en) 1976-11-24
NO141800C (no) 1980-06-04
NO750773L (fr) 1975-09-10
BG25087A3 (bg) 1978-07-12
NO141800B (no) 1980-02-04
ES440349A1 (es) 1977-03-01
JPS5827275B2 (ja) 1983-06-08
ES440347A1 (es) 1977-06-01
PH14127A (en) 1981-02-26
CH622016A5 (en) 1981-03-13
SU577983A3 (ru) 1977-10-25
SE421919B (sv) 1982-02-08
SE7502592L (fr) 1975-09-10
DE2411382C3 (de) 1979-09-06
FR2262984A1 (fr) 1975-10-03
DK92975A (fr) 1975-09-10
IL46760A0 (en) 1975-05-22
DK137188B (da) 1978-01-30
NL7502724A (nl) 1975-09-11
DK137188C (da) 1978-07-03
AT344332B (de) 1978-07-10
CH612425A5 (en) 1979-07-31
CH622015A5 (en) 1981-03-13

Similar Documents

Publication Publication Date Title
RO69615A (fr) Procede pour preparer 2,4,6-triiode-isophtaloilamide
RO67390A (fr) Procede pour -a preparation des 2-tetrahydrofurfuryle-6,7-benzo-morphanes 5,9-betha-disubstitus
RO68479A (fr) Procede pour la preparation des 1,4-dihydropyridinecarboxylates d'aralkyle
RO75006A (fr) Procede pour la preparation des mercaptoazethidionnes
BG25995A3 (bg) Метод за получаване на хексахидро-дибензо(в,d)пиран-9-они
CH612425A5 (en) Process for the preparation of novel 2-tetrahydrofurfuryl-6,7-benzomorphans
RO68793A (fr) Procede pour la preparation des copolyamides
RO75730A (fr) Procede pour la preparation des 1,2-benzizothiazole-3-ones
RO70894A (fr) Procede pour la preparation des phenylalkylamines
RO66457A (fr) Procede pour la preparation des alcoxy carbonylephenylecarbamides utilisees comme herbicides
DK137835B (da) Analogifremgangsmåde til fremstilling af thienothiazinderivater.
RO68141A (fr) Procede pour la preparation des 3a-phenyldecahydroisoquinolines
RO70706A (fr) Procede pour la preparation des diurethanes
RO73017A (fr) Procede pour la preparation des indolenines substitus
OA04641A (fr) Prcédé de préparation de 3-fluorocéphalosporines.
RO65456A (fr) Procede pour la preparation des 6-methyle-8-methylergolines substituees
RO68951A (fr) Procede pour la preparation des nouveaux composes de 8-oxyquinolin-metal-dimethyldithiocarbamate
RO72885A (fr) Procede pour la preparation des halogen-acetamides non satures
RO70739A (fr) Procede pour preparation des s-triazoles-(3,4-b)-benzothiazoles
RO66020A (fr) Procede pour la preparation des 3-pyperazinoisoquinolines
RO69254A (fr) Procede pour la preparation des pyridincarboxamidosulfonyluree
RO68703A (fr) Procede pour la preparation des 4-amino-3,5-dihalogene-phenyle-e»hanolamines
RO68478A (fr) Procede pour la preparation des 3-methylence
RO66137A (fr) Procede pour obtenir de chlorhydrate par carnytine
RO71797A (fr) Procede pour la preparation des thiocarbamates s-alkyle substitus