SE434277B - Sett att framstella nya antihelmintiskt verkande foreningar genom odling av streptomyces avermitilis - Google Patents

Sett att framstella nya antihelmintiskt verkande foreningar genom odling av streptomyces avermitilis

Info

Publication number
SE434277B
SE434277B SE7703592A SE7703592A SE434277B SE 434277 B SE434277 B SE 434277B SE 7703592 A SE7703592 A SE 7703592A SE 7703592 A SE7703592 A SE 7703592A SE 434277 B SE434277 B SE 434277B
Authority
SE
Sweden
Prior art keywords
streptomycs
antihelmintically
avermitilis
cultivating
make new
Prior art date
Application number
SE7703592A
Other languages
English (en)
Swedish (sv)
Other versions
SE7703592L (sv
Inventor
G Albers-Schonberg
R W Burg
T W Miller
R E Ormond
H Wallick
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24722350&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SE434277(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of SE7703592L publication Critical patent/SE7703592L/xx
Publication of SE434277B publication Critical patent/SE434277B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/01—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing oxygen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/44—Preparation of O-glycosides, e.g. glucosides
    • C12P19/60—Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin
    • C12P19/62—Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin the hetero ring having eight or more ring members and only oxygen as ring hetero atoms, e.g. erythromycin, spiramycin, nystatin
    • C12P19/623—Avermectin; Milbemycin; Ivermectin; C-076
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/886—Streptomyces

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)
SE7703592A 1976-04-19 1977-03-29 Sett att framstella nya antihelmintiskt verkande foreningar genom odling av streptomyces avermitilis SE434277B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US67832876A 1976-04-19 1976-04-19

Publications (2)

Publication Number Publication Date
SE7703592L SE7703592L (sv) 1977-10-20
SE434277B true SE434277B (sv) 1984-07-16

Family

ID=24722350

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7703592A SE434277B (sv) 1976-04-19 1977-03-29 Sett att framstella nya antihelmintiskt verkande foreningar genom odling av streptomyces avermitilis

Country Status (40)

Country Link
US (1) US4310519A (fr)
JP (1) JPS52151197A (fr)
AR (1) AR215000A1 (fr)
AT (1) AT357503B (fr)
AU (1) AU513641B2 (fr)
BE (1) BE853702A (fr)
BG (1) BG35900A3 (fr)
CA (1) CA1098063A (fr)
CH (1) CH639422A5 (fr)
CS (1) CS207397B2 (fr)
CY (1) CY1114A (fr)
DD (1) DD137727A5 (fr)
DE (1) DE2717040C2 (fr)
DK (1) DK146514C (fr)
ES (1) ES457932A1 (fr)
FI (1) FI57781C (fr)
FR (1) FR2348970A1 (fr)
GB (1) GB1573955A (fr)
GR (1) GR63128B (fr)
GT (1) GT197746150A (fr)
HK (1) HK38481A (fr)
HU (1) HU179041B (fr)
IE (1) IE44822B1 (fr)
IL (1) IL51854A (fr)
IT (1) IT1106424B (fr)
KE (1) KE3141A (fr)
LU (1) LU77152A1 (fr)
MY (1) MY8200087A (fr)
NL (3) NL188859C (fr)
NO (1) NO148856C (fr)
NZ (1) NZ183847A (fr)
OA (1) OA05638A (fr)
PL (1) PL108004B1 (fr)
PT (1) PT66445B (fr)
RO (1) RO71785A (fr)
SE (1) SE434277B (fr)
SU (1) SU716524A3 (fr)
YU (1) YU40814B (fr)
ZA (1) ZA772345B (fr)
ZM (1) ZM3677A1 (fr)

Families Citing this family (271)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ186851A (en) * 1977-04-11 1984-12-14 Merck & Co Inc Glycosyloxy derivatives of milbemycin and parasiticidal compositions
US4093629A (en) * 1977-04-11 1978-06-06 Merck & Co., Inc. Derivatives of antibiotic substance milbemycin and processes therefor
PH15982A (en) 1977-10-03 1983-05-18 Merck & Co Inc Selective hydrogenation producta of c-076 compounds and derivatives thereof
US4206205A (en) * 1977-10-03 1980-06-03 Merck & Co., Inc. Monosaccharide and aglycone derivatives of C-076
NZ188459A (en) * 1977-10-03 1982-09-07 Merck & Co Inc Derivatives of c-076 compounds and pesticidal compositions
IL56149A (en) * 1977-12-19 1989-09-28 Merck & Co Inc 13-halo and 13-deoxy derivatives of c-076 compounds,their preparation and method for the treatment of parasitic infections in animals therewith
US4203976A (en) * 1978-08-02 1980-05-20 Merck & Co., Inc. Sugar derivatives of C-076 compounds
US4200581A (en) * 1978-08-04 1980-04-29 Merck & Co., Inc. Alkyl derivatives of C-076 compounds
US4263168A (en) * 1979-01-10 1981-04-21 Imperial Chemical Industries Limited Olefine polymerization catalyst
US4550160A (en) * 1979-08-13 1985-10-29 Merck & Co., Inc. Processes for the interconversion of C-076 compounds
JPS5632481A (en) 1979-08-23 1981-04-01 Sankyo Co Ltd Antibiotic b-41d, its preparation, and acaricide and anthelminthic agent and repellent containing the same as active constituent
US4289760A (en) * 1980-05-02 1981-09-15 Merck & Co., Inc. 23-Keto derivatives of C-076 compounds
US4285963A (en) * 1980-08-07 1981-08-25 Merck & Co., Inc. Novel derivatives of C-076 compounds
US4385065A (en) 1980-10-23 1983-05-24 Merck & Co., Inc. Novel substances and process for their production
US4378353A (en) 1981-02-17 1983-03-29 Merck & Co., Inc. Novel C-076 compounds
US4333925A (en) 1981-05-11 1982-06-08 Merck & Co., Inc. Derivatives of C-076 compounds
US4399274A (en) 1981-07-02 1983-08-16 Merck & Co., Inc. Isolation of non-ionic lipophilic materials on macroreticular polymeric absorbents
US4412991A (en) * 1981-08-28 1983-11-01 Merck & Co., Inc. 22-Hydroxy derivatives of C-076 compounds, pharmaceutical compositions and method of use
NZ201681A (en) * 1981-09-03 1985-11-08 Merck & Co Inc Avermectin derivatives and parasiticidal compositions
US4457920A (en) * 1981-09-03 1984-07-03 Merck & Co., Inc. 4a-Substituted avermectin compounds
US4423211A (en) * 1981-12-21 1983-12-27 Merck & Co., Inc. Process for the whole broth extraction of avermectin
US4423209A (en) * 1982-02-26 1983-12-27 Merck & Co., Inc. Processes for the interconversion of avermectin compounds
US4427663A (en) 1982-03-16 1984-01-24 Merck & Co., Inc. 4"-Keto-and 4"-amino-4"-deoxy avermectin compounds and substituted amino derivatives thereof
NZ204074A (en) * 1982-05-10 1986-05-09 Merck & Co Inc Synergistic compositions containing avermectins
US4430329A (en) 1982-05-17 1984-02-07 Merck & Co., Inc. Synergistic treatment of adult canine heartworm with thiacetarsamide and ivermectin
DE3372693D1 (en) * 1982-07-22 1987-09-03 Ici Plc Methods and compositions of combating pests
US4469682A (en) * 1983-01-28 1984-09-04 Merck & Co., Inc. Avermectin and milbemycin phosphate esters, pharmaceutical compositions, and method of use
NZ207655A (en) * 1983-04-07 1986-09-10 Merck & Co Inc Synergistic veterinary compositions containing an avermectin compound and clorsulon
EP0125155A1 (fr) * 1983-04-07 1984-11-14 Merck & Co. Inc. Associations insecticides, pesticides et acaricides synergiques utilisées en agriculture
US4530921A (en) * 1983-10-03 1985-07-23 Merck & Co., Inc. Avermectin epoxide derivatives and method of use
US4560677A (en) * 1984-01-31 1985-12-24 Merck & Co., Inc. Synergistic avermectin combination for treating plant pests
US5169956A (en) * 1984-06-05 1992-12-08 American Cyanamid Company Macrolide antibiotic compounds
US4579864A (en) * 1984-06-11 1986-04-01 Merck & Co., Inc. Avermectin and milbemycin 13-keto, 13-imino and 13-amino derivatives
US5182207A (en) * 1984-09-14 1993-01-26 American Cyanamid Company Strains of streptomyces thermoarchaensis
GR852232B (fr) * 1984-09-14 1986-01-14 American Cyanamid Co
US4587247A (en) * 1985-02-25 1986-05-06 Merck & Co., Inc. Substituted and unsubstituted 13-(alkoxy)methoxy derivatives of the avermectin aglycones, compositions and use
US4666937A (en) * 1985-03-04 1987-05-19 Merck & Co., Inc. Avermectin bioconversion products
US4789684A (en) * 1985-05-02 1988-12-06 Merck & Co., Inc. Anthelmintic fermentation products of microorganisms
NZ215917A (en) 1985-05-02 1989-10-27 Merck & Co Inc 22-oh milbemycin derivatives and parasiticidal compositions
US4678774A (en) * 1985-06-06 1987-07-07 Merck & Co., Inc. Novel synergistic compositions
ES8800986A1 (es) * 1985-07-27 1987-12-01 Pfizer Un procedimiento para la produccion de un nuevo derivado de avermectina
NZ216908A (en) 1985-07-29 1989-06-28 Merck & Co Inc Avermectin derivatives
US4668696A (en) * 1985-07-29 1987-05-26 Merck & Co., Inc. Novel averonectin fermentation product of a microorganism with anthelmintic activity
US4766112A (en) * 1985-07-29 1988-08-23 Merck & Co. Inc. Anthelmintic fermentation products of a microorganism
US4622313A (en) * 1985-08-01 1986-11-11 Merck & Co., Inc. O-sulfate derivatives of avermectins and milbemycins having improved water solubility
ES8605582A1 (es) * 1985-12-11 1986-03-16 Antibioticos Sa Un procedimiento para la preparacion de avermectinas
GB8606120D0 (en) * 1986-03-12 1986-04-16 Glaxo Group Ltd Process
GB8606116D0 (en) * 1986-03-12 1986-04-16 Glaxo Group Ltd Process
EP0240274A3 (fr) * 1986-04-03 1990-03-14 Merck & Co. Inc. Avermectine comme agents pour promotion de la croissance
US5840704A (en) * 1986-07-16 1998-11-24 Pfizer Inc. Antiparasitic agents and process for their preparation
JP2587241B2 (ja) * 1986-07-24 1997-03-05 ビ−チヤム・グル−プ・ピ−エルシ− 新規化合物、その製法及びそれを含む医薬組成物
US4833168A (en) * 1986-10-03 1989-05-23 Merck & Co., Inc. Avermectin reformatsky adducts
US5077398A (en) * 1986-11-18 1991-12-31 Merck & Co., Inc. Process for isolation of avermectin B1 components with improved purity and subsequent isolaton of B2 components
US5525506A (en) * 1987-01-23 1996-06-11 Pfizer Inc. Process for production of avermectins and cultures therefor
US5238848A (en) * 1987-01-23 1993-08-24 Pfizer Inc Cultures for production of avermectins
IN167980B (fr) * 1987-01-23 1991-01-19 Pfizer
BG48572A3 (bg) * 1987-01-23 1991-03-15 Pfizer Inc., a corporation organized аnd existing under the laws of the State of Delaware Метод за получаване на авермектини
US5234831A (en) * 1987-01-23 1993-08-10 Pfizer Inc Cultures for production of B avermectins
US5077278A (en) * 1987-01-23 1991-12-31 Pfizer Inc. Non-natural demethylavermectins compositions and method of use
US4806527A (en) * 1987-03-16 1989-02-21 Merck & Co., Inc. Avermectin derivatives
US4831017A (en) * 1987-06-29 1989-05-16 Merck & Co., Inc. Increased litter size in monogastric domestic animals after treatment in mid-gestation of gravid female with avermectin or milbemycin compound
US4847243A (en) * 1987-10-08 1989-07-11 Merck & Co., Inc. Treatment for fescue toxicosis in grazing animals
US5240850A (en) * 1987-10-23 1993-08-31 Pfizer Inc. Cultures for production of avermectin aglycones
ATE89604T1 (de) * 1987-10-23 1993-06-15 Pfizer Verfahren zur herstellung von aglykonen von avermectin und sie enthaltende kulturen.
DE3880088T2 (de) * 1987-11-09 1993-07-22 Pfizer Ethylierte avermectine.
US4963667A (en) * 1987-11-10 1990-10-16 Merck & Co., Inc. Ivermectin derivative compounds and process for preparing the same
GB8726730D0 (en) * 1987-11-14 1987-12-16 Pfizer Ltd Antiparasitic agents
US4895837A (en) * 1988-01-29 1990-01-23 Merck & Co., Inc. Avermectin derivatives
GB8804440D0 (en) * 1988-02-25 1988-03-23 Pfizer Ltd Antiparasitic agents
US4918097A (en) * 1988-03-11 1990-04-17 Ciba-Geigy Corporation Insecticides and parasiticides
GB8815967D0 (en) * 1988-07-05 1988-08-10 Pfizer Ltd Antiparasitic agents
US5015662A (en) * 1988-10-18 1991-05-14 Merck & Co., Inc. Anthelmintic bioconversion products
US5120646A (en) * 1988-10-18 1992-06-09 Chen Shieh Shung T Process for the preparation of anthelmintive bioconversion products
US5015630A (en) * 1989-01-19 1991-05-14 Merck & Co., Inc. 5-oxime avermectin derivatives
US4897383A (en) * 1989-02-13 1990-01-30 Merck & Co., Inc. Avermectin derivatives
NZ232422A (en) * 1989-02-16 1992-11-25 Merck & Co Inc 13-ketal milbemycin derivatives and parasiticides
DE69023036T2 (de) 1989-03-31 1996-06-13 Merck & Co Inc Klonierung von Streptomyces avermitilis Genen zur Biosynthese von Avermectin und Verfahren zu ihrer Verwendung.
US5030622A (en) * 1989-06-02 1991-07-09 Merck & Co., Inc. Avermectin derivatives
US5023241A (en) * 1989-07-31 1991-06-11 Merck & Co., Inc. Avermectin derivatives
US5830875A (en) * 1989-10-30 1998-11-03 Merck & Co., Inc. 24-and 25-substituted avermectin and milbemycin derivatives
US5055454A (en) * 1989-10-30 1991-10-08 Merck & Co., Inc. 13-epi-avermectin derivatives useful as antiparasitic agents
JP2888586B2 (ja) * 1990-03-05 1999-05-10 社団法人北里研究所 エバーメクチンの特定成分を選択生産するための微生物およびその選択的製造法
US5114930A (en) * 1990-05-14 1992-05-19 Merck & Co., Inc. Avermectin derivatives with a spacer inserted between the disaccharide and the aglycone useful as antiparasitic agents
US5188944A (en) * 1990-06-22 1993-02-23 Merck & Co., Inc. Process for the glycosylation of avermectin agylcones
US5070015A (en) * 1990-10-15 1991-12-03 Merck & Co., Inc. Novel avermectins are produced from known microorganisms
US5192546A (en) * 1991-01-15 1993-03-09 Mycogen Corporation Synergistic pesticidal compositions
US5346698A (en) * 1991-01-15 1994-09-13 Mycogen Corporation Synergistic pesticidal compositions
US5177063A (en) * 1991-03-11 1993-01-05 Merck & Co., Inc. Avermectin compounds with a 6,5-spiroketal ring system
US5208222A (en) * 1991-03-28 1993-05-04 Merck & Co., Inc. 4"-and 4'-alkylthio avermectin derivatives
US5189026A (en) * 1991-06-07 1993-02-23 Fractal Laboratories, Inc. Treatment of human diseases involving dysregulation or dysfunction of the nervous system
US5262400A (en) * 1991-06-20 1993-11-16 Merck & Co., Inc. 4α-substituted avermectin derivatives
US5192671A (en) * 1991-06-26 1993-03-09 Merck & Co., Inc. Process for the glycosylation of avermectin compounds
EP0524686A1 (fr) * 1991-07-23 1993-01-27 Merck & Co. Inc. Procédé de 14a-hydroxylation de composés d'avermectine
EP0524687A1 (fr) * 1991-07-23 1993-01-27 Merck & Co. Inc. Procédé de glycosylation de composés d'auermectine sur la position 14a
US5240915A (en) * 1991-10-15 1993-08-31 Merck & Co., Inc. Avermectin derivatives
US5171742A (en) * 1991-10-15 1992-12-15 Merck & Co., Inc. Avermectin compounds with a 6,5-spiroketal ring system ad a 23-acyl substituent
US5248669A (en) * 1991-12-17 1993-09-28 Samir Amer Inhibition of anoxia or hypoxia-induced, endothelium-mediated vasospasm with avermectins
GB9205007D0 (en) * 1992-03-07 1992-04-22 Pfizer Ltd Antiparasitic agents
US5162363A (en) * 1992-03-18 1992-11-10 Merck & Co., Inc. 23-nor-23-thia avermectin analogs are active anthelmintic agents
US5244879A (en) * 1992-03-18 1993-09-14 Merck & Co., Inc. 23-nor-23-oxa avermectin analogs are active anthelmintic agents
ATE198493T1 (de) * 1992-03-23 2001-01-15 Merck & Co Inc Ein streptomyces avermitilis-stamm glykosyliert avermectin-verbindungen
US5312753A (en) * 1992-03-23 1994-05-17 Merck & Co., Inc. Strain of streptomyces avermitilis capable of glycosylating avermectin compounds at the 13- and 14A positions
US5229415A (en) * 1992-03-24 1993-07-20 Merck & Co., Inc. Alkylthio alkyl avermectins are active antiparasitic agents
US6103504A (en) * 1992-03-25 2000-08-15 Pfizer Inc. Process for production of avermectins and cultures therefor
IT1255135B (it) * 1992-05-05 1995-10-20 Principio attivo a base di avermectine, ceppo e procedimento per la sua preparazione e composizione veterinaria che lo contiene.
US5248678A (en) * 1992-06-30 1993-09-28 Fractal Laboratories, Inc. Methods for increasing arousal and alertness and for the amelioration of comatose states
US5241083A (en) * 1992-07-01 1993-08-31 Merck & Co., Inc. Process for converting the 13-α-hydroxy group of avermectin aglycones
US6162825A (en) * 1992-10-22 2000-12-19 The Clorox Company High fructose insecticide bait compositions
US5547955A (en) * 1992-10-22 1996-08-20 The Clorox Company High fructose insecticide bait compositions
US5292647A (en) * 1992-11-30 1994-03-08 Eli Lilly And Company Strain of streptomyces for producing avermectins and processes therewith
US5411946A (en) * 1993-02-24 1995-05-02 Merck & Co., Inc. Avermectin derivatives
US5602107A (en) * 1993-05-10 1997-02-11 Merck & Co., Inc. Pour-on formulations consisting of gylcols, glycerides and avermectin compounds
PL174488B1 (pl) * 1993-05-10 1998-08-31 Merck & Co Inc Preparat do zwalczania pasożytów zwierząt oraz sposób wytwarzania preparatu do zwalczania pasożytów zwierząt
ES2125446T3 (es) * 1993-07-23 1999-03-01 Pfizer Procedimiento para precipitar avermectinas naturales y fermentacion de las mismas.
KR100370697B1 (ko) * 1993-08-19 2003-06-11 머크 앤드 캄파니 인코포레이티드 4'-데옥시-4'-에피-메틸아미노에버멕틴B1a/B1b벤조산염의순수한결정성반수화물형태B,이의제조방법및이를함유하는해충방제용조성물
US5478929A (en) * 1993-09-15 1995-12-26 Merck & Co., Inc. Bioconversion products of 27-hydroxy avermectin
US5380838A (en) * 1993-10-08 1995-01-10 Merck & Co. Inc. Stable solvates of avermectin compounds
US5399582A (en) * 1993-11-01 1995-03-21 Merck & Co., Inc. Antiparasitic agents
TW327125B (en) * 1994-02-07 1998-02-21 Merck & Co Inc Composition and method for protecting against pine exhausted
GB9402916D0 (en) * 1994-02-16 1994-04-06 Pfizer Ltd Antiparasitic agents
US5578581A (en) * 1994-04-26 1996-11-26 Merck & Co., Inc. Active avermectin analogue
US5550153A (en) * 1994-11-14 1996-08-27 Kerz; Phillip D. Method for treating heartworm-infected canines
NZ302661A (en) * 1995-02-24 1999-10-28 Novartis Ag Composition for controlling parasites comprising n phenyl-n'-benzoylurea derivatives
BR9607965A (pt) * 1995-03-20 1998-07-14 Merck & Co Inc Composto composição farmacêutica e processo para tratar uma doença parasítica em um mamífero
DE19520275A1 (de) * 1995-06-02 1996-12-05 Bayer Ag Endoparasitizide Mittel
US6124359A (en) * 1995-10-20 2000-09-26 Mycogen Corporation Materials and methods for killing nematodes and nematode eggs
US5674897A (en) * 1995-10-20 1997-10-07 Mycogen Corporation Materials and methods for controlling nematodes
DE19613972A1 (de) * 1996-04-09 1997-10-16 Bayer Ag Injektionsformulierungen von Avermectinen und Milbemycinen auf Basis von Rizinusöl
AUPN933396A0 (en) * 1996-04-17 1996-05-09 Pfizer Pty Limited Non-aqueuos oral-drench compositions containing avermectin compounds
DE69725745D1 (de) 1996-06-05 2003-11-27 Ashmont Holdings Ltd Injizierbare zusammensetzungen
US6403308B1 (en) 1997-04-30 2002-06-11 Mcgill University Methods for detecting and reversing resistance to macrocyclic lactone compounds
US6114376A (en) * 1997-04-30 2000-09-05 Mcgill University Methods for using macrocyclic lactone compounds as multidrug resistance reversing agents in tumor and other cells
JP3925900B2 (ja) * 1997-12-03 2007-06-06 メルク エンド カムパニー インコーポレーテッド 水素化ヒマシ油を含有する持続性注射剤
YU50900A (sh) * 1998-02-13 2004-03-12 Pfizer Produsts Inc. Streptomyces avermitilis gen koji usmerava odnos b2:b1 avermektina
ES2359973T3 (es) * 1998-03-19 2011-05-30 MERCK SHARP & DOHME CORP. Composiciones poliméricas líquidas para la liberación controlada de sustancias bioactivas.
GB9825402D0 (en) 1998-11-19 1999-01-13 Pfizer Ltd Antiparasitic formulations
US6787342B2 (en) 2000-02-16 2004-09-07 Merial Limited Paste formulations
DE10013914A1 (de) 2000-03-21 2001-09-27 Bayer Ag Wirkstoffkombinationen mit insektiziden und akariziden Eigenschaften
US6399651B1 (en) * 2000-06-29 2002-06-04 L. Dean Parks Method of treating dermatoses using avermectin compound
US7897559B2 (en) * 2000-06-29 2011-03-01 Parks L Dean Dermatological composition and kit containing avermectin compound for treating dermatological conditions
DE10055941A1 (de) 2000-11-10 2002-05-23 Bayer Ag Wirkstoffkombinationen mit insektiziden und akariziden Eigenschaften
DE10059606A1 (de) * 2000-12-01 2002-06-06 Bayer Ag Wirkstoffkombinationen
AR036872A1 (es) 2001-08-13 2004-10-13 Du Pont Compuesto de antranilamida, composicion que lo comprende y metodo para controlar una plaga de invertebrados
DE10203688A1 (de) * 2002-01-31 2003-08-07 Bayer Cropscience Ag Synergistische insektizide Mischungen
CN1630712B (zh) * 2002-02-12 2011-09-28 辉瑞产品公司 指导b2:b1除虫菌素比例的除虫链霉菌基因
DE10207241A1 (de) * 2002-02-21 2003-09-04 Bayer Cropscience Ag Synergistische insektizide Mischungen
GB2386066A (en) * 2002-02-28 2003-09-10 Norbrook Lab Ltd Long-acting parasiticidal composition with improved bioavailability comprising a salicylanilide, a further anti-parasitic compound & a polymeric species
US20060205681A1 (en) * 2002-06-21 2006-09-14 Maryam Moaddeb Homogenous paste formulations
US7001889B2 (en) * 2002-06-21 2006-02-21 Merial Limited Anthelmintic oral homogeneous veterinary pastes
US6764999B2 (en) 2002-07-11 2004-07-20 Stephen E. Bachman Nasal delivery of parasiticides
US20040077703A1 (en) * 2002-10-02 2004-04-22 Soll Mark D. Nodulisporic acid derivative spot-on formulations for combating parasites
DE10248257A1 (de) * 2002-10-16 2004-04-29 Bayer Cropscience Ag Wirkstoffkombinationen im insektiziden und akariziden Eigenschaften
GB0229804D0 (en) * 2002-12-20 2003-01-29 Syngenta Participations Ag Avermection b1 and avermectin b1 monosaccharide derivatives having an alkoxymethyl substituent in the 4"- or 4'-position
GB0316377D0 (en) 2003-07-12 2003-08-13 Norbrook Lab Ltd Parasiticidal composition
DE10353281A1 (de) 2003-11-14 2005-06-16 Bayer Cropscience Ag Wirkstoffkombination mit insektiziden und akariziden Eigenschaften
US7531186B2 (en) * 2003-12-17 2009-05-12 Merial Limited Topical formulations comprising 1-N-arylpyrazole derivatives and amitraz
US7671034B2 (en) * 2003-12-19 2010-03-02 Merial Limited Stabilized formulation of ivermectin feed premix with an extended shelf life
US7666444B2 (en) 2004-02-02 2010-02-23 Wyeth Antiparasitic composition
US7493609B2 (en) * 2004-08-30 2009-02-17 International Business Machines Corporation Method and apparatus for automatic second-order predictive commoning
MX2007003378A (es) 2004-09-23 2007-05-10 Schering Plough Ltd Control de parasitos en animales mediante el uso de nuevos derivados de trifluorometansulfonanilida oxima eter.
DE102004053964A1 (de) * 2004-11-09 2006-05-11 Bayer Healthcare Ag Mittel gegen Demodikose
EP1811841B1 (fr) * 2004-11-19 2009-10-28 Schering-Plough Ltd. Lutte contre des parasites chez les animaux au moyen de derives parasiticides de 2-phenyl-3-(1h-pyrrol-2-yl) acrylonitrile
GB0501220D0 (en) * 2005-01-21 2005-03-02 Norbrook Lab Ltd Anthelmintic composition
US8362086B2 (en) 2005-08-19 2013-01-29 Merial Limited Long acting injectable formulations
US20080027011A1 (en) * 2005-12-20 2008-01-31 Hassan Nached Homogeneous paste and gel formulations
US8119667B2 (en) * 2005-12-29 2012-02-21 Schering-Plough Animal Health Corporation Carbonates of fenicol antibiotics
EP1849363A1 (fr) * 2006-03-09 2007-10-31 Cheminova A/S Combinations synergiques d'un plaguicide agoniste des canaux à chlorure actives par le glutamate ou le GABA et au moins un d'entre la vitamine E et la niacin
US20070238700A1 (en) * 2006-04-10 2007-10-11 Winzenberg Kevin N N-phenyl-1,1,1-trifluoromethanesulfonamide hydrazone derivative compounds and their usage in controlling parasites
TWI422328B (zh) 2006-06-19 2014-01-11 Univ California 結合有殺線蟲之種子塗覆物的生物控制劑
US7759381B2 (en) 2006-07-05 2010-07-20 Aventis Agriculture 1-aryl-5-alkyl pyrazole derivative compounds, processes of making and methods of using thereof
DE102007007750A1 (de) * 2006-08-17 2008-02-21 Bayer Cropscience Ag Avermectinderivate
FR2906468B1 (fr) * 2006-09-28 2012-09-21 Galderma Sa Utilisation de composes de la famille des avermectines pour le traitement de desordres dermatologiques
MX2009006467A (es) * 2006-12-13 2009-08-21 Schering Plough Ltd Profarmacos solubles en agua de cloranfenicol, tiamfenicol y analogos de los mismos.
EP2091909A1 (fr) * 2006-12-13 2009-08-26 Schering-Plough Ltd. Promedicaments de florfenicol solubles dans l'eau et analogues
US8901163B2 (en) 2007-01-03 2014-12-02 Galderma S.A. Method of treating hyperesthesia, paresthesia, dolor, and pruritus caused by insect stings or noxious weeds or plants using avermectin compound
US8088801B2 (en) 2007-05-15 2012-01-03 Merial Limited Aryloazol-2-yl cyanoethylamino compounds, method of making and method of using thereof
TWI430995B (zh) 2007-06-26 2014-03-21 Du Pont 萘異唑啉無脊椎有害動物控制劑
NO2957284T3 (fr) 2007-06-27 2018-06-16
EP2008517A1 (fr) 2007-06-29 2008-12-31 Bayer CropScience AG Combinaisons dýagents acaricides
US8425925B2 (en) * 2007-06-29 2013-04-23 Y-Tex Corporation Pesticidal tag
BRPI0702873A2 (pt) 2007-06-29 2011-03-15 Y Tex Corp brinco pesticida
TWI556741B (zh) 2007-08-17 2016-11-11 英特威特國際股份有限公司 異唑啉組成物及其作為抗寄生蟲藥上的應用
EP2039248A1 (fr) * 2007-09-21 2009-03-25 Bayer CropScience AG Combinaisons d'agents actifs à propriétés insecticides et acaricides
DE102007045922A1 (de) 2007-09-26 2009-04-02 Bayer Cropscience Ag Wirkstoffkombinationen mit insektiziden und akariziden Eigenschaften
BRPI0819849B8 (pt) 2007-11-26 2021-05-25 Merial Ltd sistemas de solvente para formulações pour on para combater parasitas
US20110028495A1 (en) 2007-12-21 2011-02-03 Ernst Baumann THE USE OF 6-HALOGENO-[1,2,4]-TRIAZOLO-[1,5-a]-PYRIMIDINE COMPOUNDS FOR COMBATING PESTS IN AND ON ANIMALS
TWI468407B (zh) 2008-02-06 2015-01-11 Du Pont 中離子農藥
EP2127522A1 (fr) 2008-05-29 2009-12-02 Bayer CropScience AG Combinaisons de principes actifs presentant des propriétés insecticides et acaricides
US20100022469A1 (en) * 2008-06-24 2010-01-28 Majid Razzak Anthelminthic formulations
US8314252B2 (en) * 2008-07-30 2012-11-20 Intervet Inc. Process for preparing oxazoline-protected aminodiol compounds useful as intermediates to florfenicol
CA2675093A1 (fr) * 2008-08-08 2010-02-08 Michael L. Corrado Traitement d'infestation de punaises et d'acariens
AR074024A1 (es) 2008-11-14 2010-12-15 Merial Ltd Compuesto de arilazol-2-il-cianoetilamino enantiomericamente enriquecidos, composicion plaguicida y su uso para prevenir la infeccion parasitaria
US8683346B2 (en) * 2008-11-17 2014-03-25 Sap Portals Israel Ltd. Client integration of information from a supplemental server into a portal
PL396375A1 (pl) 2008-11-19 2012-04-23 Merial Limited Kompozycje obejmujące arylopirazol i/lub formamidynę, sposoby i zastosowania je obejmujące
US9173728B2 (en) 2008-11-19 2015-11-03 Merial Inc. Multi-cavity container having offset indentures for dispensing fluids
MX2011005726A (es) 2008-12-04 2011-07-29 Merial Ltd Derivados de avermectina y milbemicina dimericos.
EP2227951A1 (fr) 2009-01-23 2010-09-15 Bayer CropScience AG Utilisation des composés d'énaminocarbonyle de combattre des virus transmis par les insectes
CN102355891A (zh) 2009-03-17 2012-02-15 英特威国际有限公司 大环内酯药物递送系统
MX341143B (es) * 2009-03-25 2016-08-10 Bayer Intellectual Property Gmbh * Combinaciones de principios activos nematicidas, insecticidas y acaricidas que comprenden piridiletilbenzamida e insecticidas.
US9133209B2 (en) 2009-07-30 2015-09-15 Merial, Inc. Insecticidal 4-amino-thieno[2,3-D]-pyrimidine compounds and methods of their use
AU2010279587A1 (en) 2009-08-05 2012-02-09 E. I. Du Pont De Nemours And Company Mesoionic pesticides
UA110924C2 (uk) 2009-08-05 2016-03-10 Е. І. Дю Пон Де Немур Енд Компані Мезоіонні пестициди
UA107804C2 (xx) 2009-08-05 2015-02-25 Du Pont Суміші мезоіонних пестицидів
KR20120050467A (ko) 2009-08-05 2012-05-18 이 아이 듀폰 디 네모아 앤드 캄파니 메소이온성 살충제
BR112012008185A2 (pt) 2009-10-07 2016-08-16 Wyeth Llc composições que compreendem adjuvante, macrolídeo e antígeno proteináceo, e métodos para uso dessas composições
EP2327410A1 (fr) 2009-10-28 2011-06-01 Consiglio Nazionale Delle Ricerche - Infm Istituto Nazionale Per La Fisica Della Materia Avermectines et milbémycines pour le traitement d'infections à Flavivirus
WO2011069143A1 (fr) 2009-12-04 2011-06-09 Merial Limited Composés pesticides bis-organosulfurés
PL2513104T3 (pl) 2009-12-17 2016-08-31 Merial Inc Przeciwpasożytnicze związki dihydroazolu i zawierające je kompozycje
CA2784141C (fr) 2009-12-17 2017-10-24 Merial Limited Compositions contenant des composes de lactone macrocyclique et des spiro-dioxepino-indoles
CN102811617A (zh) 2010-01-22 2012-12-05 拜耳知识产权有限责任公司 杀螨和/或杀虫活性物质结合物
UY33282A (es) 2010-03-25 2011-09-30 Novartis Ag Composiciones endoparasiticidas
UA108641C2 (uk) 2010-04-02 2015-05-25 Паразитицидна композиція, яка містить чотири активних агенти, та спосіб її застосування
EP2382865A1 (fr) 2010-04-28 2011-11-02 Bayer CropScience AG Combinaisons d'agents actifs synergiques
DK2568980T3 (en) 2010-05-12 2015-11-30 Merial Inc INJECTABLE PARASITICIDE FORMULATIONS OF LEVAMISOL AND MACROCYCLIC LACTONS
MY156670A (en) 2010-05-27 2016-03-15 Du Pont Crystalline form of 4-[5-[3-chloro-5-(trifluoromethly)phenyl]-4,5-dihydro-5-(trifluoromethyl)-3-isoxazolyl]-n-[2-oxo-2-[(2,2,2-trifluoroethyl) amino]ethyl]-1-naphthalenecarboxamide
AR081970A1 (es) 2010-06-24 2012-10-31 Intervet Int Bv Formulacion inyectable de una lactona macrociclica y levamisol, formulacion y uso veterinario
WO2012001083A2 (fr) 2010-06-29 2012-01-05 Ceva Sante Animale Sa Nouvelles compositions injectables d'éprinomectine
CA2811924C (fr) 2010-10-20 2015-06-16 Galderma S.A. Methode de traitement des hemorroides a l'aide d'un compose de lactone macrocyclique
US8901090B2 (en) 2010-10-20 2014-12-02 Galderma S.A. Method of treating otitis externa using macrocyclic lactone compound
LT2640728T (lt) 2010-11-16 2017-03-27 Merial, Inc. Nauji monenzino dariniai, skirti pirmuonių sukeltų infekcijų gydymui
NZ612185A (en) 2010-12-07 2015-10-30 Merial Inc Topical combination formulations of macrocyclic lactones with synthetic pyrethroids
WO2012087630A1 (fr) 2010-12-20 2012-06-28 E.I. Du Pont De Nemours And Company Composés de pyridine et de pyrimidine utilisés pour lutter contre des nuisibles invertébrés
GB201021836D0 (en) 2010-12-21 2011-02-02 Norbrook Lab Ltd Topical Composition
WO2012140207A2 (fr) 2011-04-15 2012-10-18 Syngenta Participations Ag Procédé de lutte contre les parasites nématodes
US8946270B2 (en) 2011-06-27 2015-02-03 Merial Limited Amido-pyridyl ether compounds and compositions and their use against parasites
US20120329832A1 (en) 2011-06-27 2012-12-27 Jean Delaveau Novel Insect-Repellent Coumarin Derivatives, Syntheses, and Methods of Use
CN102356769A (zh) * 2011-09-02 2012-02-22 魏振东 一种含有机质的可湿性粉剂农药
JP6366102B2 (ja) 2011-09-12 2018-08-01 メリアル インコーポレイテッド イソオキサゾリン活性薬を含む殺寄生虫性組成物、その方法および使用
WO2013044118A2 (fr) 2011-09-23 2013-03-28 Merial Limited Modélisation indirecte de molécules répulsives inédites actives contre les insectes, les acariens et autres arthropodes
JP6249568B2 (ja) 2011-11-17 2017-12-20 メリアル インコーポレイテッド アリールピラゾールと置換イミダゾールを含む組成物、その使用方法
MX379693B (es) 2011-12-02 2025-03-11 Merial Ltd Formulaciones de moxidectina inyectables de larga acción y formas de cristal de moxidectina novedosas.
RS58370B1 (sr) 2012-02-06 2019-03-29 Merial Inc Paraziticidne oralne veterinarske kompozicije koje sadrže sistemski delujuća aktivna sredstva, metodi i primene istih
JO3626B1 (ar) 2012-02-23 2020-08-27 Merial Inc تركيبات موضعية تحتوي على فيبرونيل و بيرميثرين و طرق استخدامها
WO2013158422A1 (fr) 2012-04-17 2013-10-24 E. I. Du Pont De Nemours And Company Composés hétérocycliques pour la lutte contre des animaux nuisibles invertébrés
CN104395295B (zh) 2012-04-20 2018-03-06 梅里亚有限公司 包含苯并咪唑衍生物的杀寄生物的组合物，其方法和用途
CA2891926A1 (fr) 2012-11-20 2014-05-30 Merial, Inc. Composes et compositions anthelminthiques et leur procede d'utilisation
SMT201800309T1 (it) 2013-01-31 2018-07-17 Merial Inc Metodo per trattare e curare leishmaniosi utilizzando fexinidazolo
WO2014169092A1 (fr) 2013-04-12 2014-10-16 Zoetis Llc Composition de lactones macrocycliques, de lévamisole, d'un sucre aminé et d'un agent antiparasitaire additionnel
DK3063144T3 (da) 2013-11-01 2021-10-25 Boehringer Ingelheim Animal Health Usa Inc Antiparasitære og pesticid-isoxazolinforbindelser
EP2886640A1 (fr) 2013-12-18 2015-06-24 Riga Technical University Procédé d'isolation pour milbemycine A3 et A4
NZ726251A (en) 2014-04-17 2017-11-24 Merial Inc Use of malononitrile compounds for protecting animals from parasites
JP6616786B2 (ja) 2014-05-19 2019-12-04 メリアル インコーポレイテッド 駆虫性化合物
EP3157912B1 (fr) 2014-06-19 2019-02-20 Merial, Inc. Compositions parasiticides comprenant des dérivés d'indole, leurs procédés et leurs utilisations
US10864193B2 (en) 2014-10-31 2020-12-15 Boehringer Ingelheim Animal Health USA Inc. Parasiticidal compositions comprising fipronil at high concentrations
EP3023092A1 (fr) 2014-11-20 2016-05-25 Ceva Sante Animale Compositions parentérales d'éprinomectine
PY1609250A (es) 2015-02-26 2018-03-01 Merial Inc Formulaciones inyectables de acción prolongada que comprenden un agente activo isoxazolina, métodos y usos de las mismas
WO2016164487A1 (fr) 2015-04-08 2016-10-13 Merial, Inc. Formulations injectables à action prolongée comprenant un principe actif isoxazoline, méthodes et utilisations de celles-ci
PT3298027T (pt) 2015-05-20 2022-01-26 Boehringer Ingelheim Animal Health Usa Inc Compostos depsipéptidos antelmínticos
WO2016191389A2 (fr) 2015-05-27 2016-12-01 Merial, Inc. Compositions contenant des anticorps igy antimicrobiens, pour le traitement et la prévention de troubles et de maladies causés par des micro-organismes compromettant la santé orale (ohc)
KR101687973B1 (ko) 2015-12-08 2016-12-21 주식회사 씨티씨바이오 마이크로필름 코팅을 이용한 동물 사료용 프리믹스 제조방법
UY40429A (es) 2016-02-24 2023-10-13 Boehringer Ingelheim Animal Health Usa Inc Compuestos antiparasitarios de isoxazolina, formulaciones inyectables de acción prolongada que los comprenden, métodos y usos de los mismos
RU2630316C1 (ru) * 2016-06-24 2017-09-07 Карина Микаилевна Мирзаева Препарат для борьбы с насекомыми-кератофагами
WO2018039508A1 (fr) 2016-08-25 2018-03-01 Merial, Inc. Procédé de réduction d'effets indésirables dans des traitements antiparasitaires
WO2018055022A1 (fr) 2016-09-22 2018-03-29 Syngenta Participations Ag Mélanges pesticides
WO2018071535A1 (fr) 2016-10-14 2018-04-19 Merial, Inc. Composés de vinyl-isoxazoline pesticides et parasiticides
CN110167921A (zh) 2016-11-16 2019-08-23 勃林格殷格翰动物保健美国公司 驱蠕虫缩肽化合物
EP3644741B1 (fr) 2017-06-26 2023-06-07 Boehringer Ingelheim Animal Health USA Inc. Compositions de granulés parasiticides à double action, leurs procédés et utilisations
WO2019036407A1 (fr) 2017-08-14 2019-02-21 Merial, Inc. Composés de pyrazole-isoxazoline à activité pesticide et parasiticide
WO2019152808A1 (fr) 2018-02-01 2019-08-08 Yale University Compositions et procédés d'inhibition d'anticorps pénétrant dans le noyau
US11583545B2 (en) 2018-02-08 2023-02-21 Boehringer Ingelheim Animal Health USA Inc. Parasiticidal compositions comprising eprinomectin and praziquantel, methods and uses thereof
KR20250044476A (ko) 2018-07-09 2025-03-31 베링거잉겔하임베트메디카게엠베하 구충성 헤테로시클릭 화합물
CN113260419A (zh) 2018-11-20 2021-08-13 勃林格殷格翰动物保健美国公司 吲唑基氰基乙基氨基化合物、其组合物、其制备方法和其使用方法
NZ776819A (en) 2019-01-16 2023-04-28 Boehringer Ingelheim Animal Health Usa Inc Topical compositions comprising a neonicotinoid and a macrocyclic lactone, methods and uses thereof
PY2013845A (es) 2019-03-01 2021-02-09 Boehringer Ingelheim Animal Health Usa Inc Composiciones inyectables de clorsulón, sus métodos y usos
PE20220281A1 (es) 2019-03-19 2022-02-25 Boehringer Ingelheim Animal Health Usa Inc Compuestos de aza-benzotiofeno y aza-benzofurano como antihelminticos
BR112022000982A2 (pt) 2019-07-22 2022-03-08 Intervet Int Bv Forma de dosagem veterinária mastigável macia
CN116249704B (zh) 2020-05-29 2025-12-16 勃林格殷格翰动物保健有限公司 驱虫用杂环化合物
WO2022034226A1 (fr) 2020-08-14 2022-02-17 Universidad De Navarra Compositions d'avermectine et de milbemycine pour inhalation
CA3205997A1 (fr) 2020-12-21 2022-06-30 University Of Georgia Research Foundation Inc. Collier parasiticide comprenant des composes d'isoxazoline
EP4436383A1 (fr) 2021-11-25 2024-10-02 Syngenta Crop Protection AG Compositions pesticides
WO2025257633A1 (fr) 2024-06-12 2025-12-18 Boehringer Ingelheim Vetmedica Gmbh Formulations injectables à action prolongée contenant de l'huile de ricin et procédés d'utilisation associés

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3950360A (en) * 1972-06-08 1976-04-13 Sankyo Company Limited Antibiotic substances
JPS4914624A (fr) * 1972-06-08 1974-02-08
US4134973A (en) * 1977-04-11 1979-01-16 Merck & Co., Inc. Carbohydrate derivatives of milbemycin and processes therefor
US4160861A (en) * 1977-10-03 1979-07-10 Merck & Co., Inc. Method for the separation of antibiotic macrolides
US4160083A (en) * 1977-10-03 1979-07-03 Merck & Co., Inc. Process for the separation of antibiotic macrolides
US4161583A (en) * 1977-10-03 1979-07-17 Merck & Co., Inc. Method for the separation and purification of antibiotic macrolides
US4160084A (en) * 1977-10-11 1979-07-03 Merck & Co., Inc. Method for the separation of antibiotic macrolides

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US4310519A (en) 1982-01-12
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OA05638A (fr) 1981-04-30
SE7703592L (sv) 1977-10-20
CS207397B2 (en) 1981-07-31
JPS52151197A (en) 1977-12-15
NL971001I2 (nl) 1997-08-01
ES457932A1 (es) 1978-06-01
AT357503B (de) 1980-07-10
DE2717040A1 (de) 1977-11-10
GB1573955A (en) 1980-08-28
IE44822L (en) 1977-10-19
NO771211L (no) 1977-10-20
NL188859B (nl) 1992-05-18
KE3141A (en) 1981-07-24

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