SE7901276L - Aminosockerderivat - Google Patents

Aminosockerderivat

Info

Publication number: SE7901276L
Authority: SE; Sweden
Prior art keywords: sugar derivatives; amino sugar; trestatin; inhibition; compositions
Prior art date: 1978-02-14

Application number

SE7901276A

Other languages

Unknown language ( )

English (en)

Swedish (sv)

Inventor

Y Suhara

K Ogawa

K Yokose

K Watanabe

Original Assignee

Hoffmann La Roche

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1978-02-14

Filing date

1979-02-13

Publication date

1979-08-15

1979-02-13 Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche

1979-08-15 Publication of SE7901276L publication Critical patent/SE7901276L/

Links

150000002336 glycosamine derivatives Chemical class 0.000 title 1
239000000203 mixture Substances 0.000 abstract 3
WEDWQCPYKKZMDF-UHFFFAOYSA-N 2-[5-[5-[5-[3,4-dihydroxy-6-methyl-5-[[4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino]oxan-2-yl]oxy-3,4-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3,4-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3,4-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-6-(hydro Chemical compound OC1C(O)C(NC2C(C(O)C(O)C(CO)=C2)O)C(C)OC1OC(C(C1O)O)C(CO)OC1OC(C(C1O)O)C(CO)OC1OC(C(C1O)O)C(CO)OC1OC1OC(CO)C(O)C(O)C1O WEDWQCPYKKZMDF-UHFFFAOYSA-N 0.000 abstract 2
229930186167 Trestatin Natural products 0.000 abstract 2
230000005764 inhibitory process Effects 0.000 abstract 2
150000003839 salts Chemical class 0.000 abstract 2
PYVAAPGPTLLDGV-AGKSRYJLSA-N (2r,3r,4s,5s,6r)-2-[(2r,3r,4r,5s,6r)-5-[(2r,3r,4r,5s,6r)-5-[(2r,3r,4r,5s,6r)-5-[(2r,3r,4s,5s,6r)-5-[[(1s,4r,5r,6s)-4-[(2s,3r,4r,5s,6r)-5-[(2r,3r,4s,5s,6r)-3,4-dihydroxy-6-methyl-5-[[(1s,4r,5s,6s)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino] Chemical compound O([C@H]1O[C@H](CO)[C@H]([C@@H]([C@H]1O)O)O[C@H]1O[C@H](CO)[C@H]([C@@H]([C@H]1O)O)O[C@H]1O[C@H](CO)[C@H]([C@@H]([C@H]1O)O)O[C@H]1O[C@H](C)[C@H]([C@@H]([C@H]1O)O)N[C@@H]1[C@H](O)[C@@H](O)[C@@H](C(=C1)CO)O[C@H]1O[C@H](CO)[C@H]([C@@H]([C@H]1O)O)O[C@H]1O[C@@H]([C@H]([C@H](O)[C@H]1O)N[C@@H]1[C@@H]([C@@H](O)[C@H](O)C(CO)=C1)O)C)[C@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O PYVAAPGPTLLDGV-AGKSRYJLSA-N 0.000 abstract 1
101710184309 Probable sucrose-6-phosphate hydrolase Proteins 0.000 abstract 1
102400000472 Sucrase Human genes 0.000 abstract 1
101710112652 Sucrose-6-phosphate hydrolase Proteins 0.000 abstract 1
PYVAAPGPTLLDGV-UHFFFAOYSA-N Trestatin A Natural products OC1C(O)C(NC2C(C(O)C(O)C(CO)=C2)O)C(C)OC1OC(C(C1O)O)C(CO)OC1OC(C(=C1)CO)C(O)C(O)C1NC(C(C1O)O)C(C)OC1OC(C(C1O)O)C(CO)OC1OC(C(C1O)O)C(CO)OC1OC(C(C1O)O)C(CO)OC1OC1OC(CO)C(O)C(O)C1O PYVAAPGPTLLDGV-UHFFFAOYSA-N 0.000 abstract 1
102000004139 alpha-Amylases Human genes 0.000 abstract 1
108090000637 alpha-Amylases Proteins 0.000 abstract 1
229940024171 alpha-amylase Drugs 0.000 abstract 1
235000011073 invertase Nutrition 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/99—Enzyme inactivation by chemical treatment
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/26—Preparation of nitrogen-containing carbohydrates

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Genetics & Genomics (AREA)
Zoology (AREA)
Wood Science & Technology (AREA)
Biochemistry (AREA)
Biotechnology (AREA)
Molecular Biology (AREA)
Bioinformatics & Cheminformatics (AREA)
General Health & Medical Sciences (AREA)
Microbiology (AREA)
General Chemical & Material Sciences (AREA)
General Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
Medicinal Chemistry (AREA)
Biomedical Technology (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Enzymes And Modification Thereof (AREA)
Saccharide Compounds (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

SE7901276A 1978-02-14 1979-02-13 Aminosockerderivat SE7901276L (sv)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB583478		1978-02-14

Publications (1)

Publication Number	Publication Date
SE7901276L true SE7901276L (sv)	1979-08-15

Family

ID=9803510

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SE7901276A SE7901276L (sv)	1978-02-14	1979-02-13	Aminosockerderivat

Country Status (26)

Country	Link
US (1)	US4273765A (cs)
EP (1)	EP0003616B1 (cs)
JP (1)	JPS54163511A (cs)
AR (1)	AR219150A1 (cs)
AT (1)	AT367451B (cs)
AU (1)	AU527318B2 (cs)
CA (1)	CA1121290A (cs)
DE (2)	DE2905649A1 (cs)
DK (1)	DK149599C (cs)
ES (1)	ES477653A1 (cs)
FI (1)	FI63062C (cs)
FR (1)	FR2416901A1 (cs)
GR (1)	GR72817B (cs)
HU (1)	HU181442B (cs)
IE (1)	IE47916B1 (cs)
IL (1)	IL56626A0 (cs)
LU (1)	LU80906A1 (cs)
MC (1)	MC1253A1 (cs)
NL (1)	NL7901182A (cs)
NO (1)	NO153011C (cs)
NZ (1)	NZ189625A (cs)
PH (1)	PH15084A (cs)
PT (1)	PT69218A (cs)
SE (1)	SE7901276L (cs)
YU (1)	YU41437B (cs)
ZA (1)	ZA79528B (cs)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0056194B1 (en)	1981-01-05	1984-09-12	Takeda Chemical Industries, Ltd.	N-substituted pseudo-aminosugars, their production and use
JPS57146713A (en) *	1981-03-09	1982-09-10	Akira Endo	Hypoglycemic
US4595678A (en) *	1982-03-19	1986-06-17	Takeda Chemical Industries, Ltd.	N-substituted pseudo-aminosugars and pharmaceutical compositions containing same
US4678812A (en) *	1986-05-30	1987-07-07	E. I. Du Pont De Nemours And Company	Trehalose as stabilizer and tableting excipient
US4762857A (en) *	1986-05-30	1988-08-09	E. I. Du Pont De Nemours And Company	Trehalose as stabilizer and tableting excipient
US4885361A (en) *	1987-07-31	1989-12-05	Hoffmann-La Roche Inc.	Sulfated oligosaccharides
EP0559795B1 (en) *	1990-11-30	1995-12-27	Monoclonetics International, Inc.	Methods for the diagnosis of chronic lower back and cervical pain
TW381025B (en) *	1993-08-05	2000-02-01	Hoffmann La Roche	Pharmaceutical composition containing a glucosidase inhibitor and a lipase inhibitor
US7022684B2 (en) *	2000-05-24	2006-04-04	Pfizer Inc.	Treatment of rumen acidosis with α-amylase inhibitors
ATE343391T1 (de) *	2000-05-24	2006-11-15	Pfizer	Behandlung von pansenacidose mit amylasehemmern
US7829552B2 (en)	2003-11-19	2010-11-09	Metabasis Therapeutics, Inc.	Phosphorus-containing thyromimetics
US7262318B2 (en) *	2004-03-10	2007-08-28	Pfizer, Inc.	Substituted heteroaryl- and phenylsulfamoyl compounds
US20050288340A1 (en) *	2004-06-29	2005-12-29	Pfizer Inc	Substituted heteroaryl- and phenylsulfamoyl compounds
MX2007005137A (es) *	2004-11-23	2007-06-22	Warner Lambert Co	Derivados del acido 7-(2h-pyrazol-3-il)-3, 5-dihidroxi-heptanoico como inhibidores de hmg co-a reductasa para el tratamiento de lipidemia.
US7741317B2 (en)	2005-10-21	2010-06-22	Bristol-Myers Squibb Company	LXR modulators
US7888376B2 (en)	2005-11-23	2011-02-15	Bristol-Myers Squibb Company	Heterocyclic CETP inhibitors
US8404896B2 (en)	2006-12-01	2013-03-26	Bristol-Myers Squibb Company	N-((3-benzyl)-2,2-(bis-phenyl)-propan-1-amine derivatives as CETP inhibitors for the treatment of atherosclerosis and cardiovascular diseases
MX354786B (es)	2007-06-04	2018-03-21	Synergy Pharmaceuticals Inc	Agonistas de guanilato ciclasa utiles para el tratamiento de trastornos gastrointestinales, inflamacion, cancer y otros trastornos.
US8969514B2 (en)	2007-06-04	2015-03-03	Synergy Pharmaceuticals, Inc.	Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
JP5115623B2 (ja) *	2008-04-11	2013-01-09	アステラス製薬株式会社	アミノ糖化合物及びその生産方法
CA2726917C (en)	2008-06-04	2018-06-26	Synergy Pharmaceuticals Inc.	Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
EP2321341B1 (en)	2008-07-16	2017-02-22	Synergy Pharmaceuticals Inc.	Agonists of guanylate cyclase useful for the treatment of gastrointestinal, inflammation, cancer and other disorders
US20120046364A1 (en)	2009-02-10	2012-02-23	Metabasis Therapeutics, Inc.	Novel Sulfonic Acid-Containing Thyromimetics, and Methods for Their Use
EP2571860A1 (en)	2010-05-21	2013-03-27	Pfizer Inc	2-phenyl benzoylamides
WO2012027331A1 (en)	2010-08-27	2012-03-01	Ironwood Pharmaceuticals, Inc.	Compositions and methods for treating or preventing metabolic syndrome and related diseases and disorders
US9616097B2 (en)	2010-09-15	2017-04-11	Synergy Pharmaceuticals, Inc.	Formulations of guanylate cyclase C agonists and methods of use
CA2828343A1 (en)	2011-03-04	2012-09-13	The Scripps Research Institute	Edn3-like peptides and uses thereof
US20150050371A1 (en)	2012-03-09	2015-02-19	Biotropics Malaysia Berhad	Extract Formulations of Rhodamnia Cinerea And Uses Thereof
WO2014151200A2 (en)	2013-03-15	2014-09-25	Synergy Pharmaceuticals Inc.	Compositions useful for the treatment of gastrointestinal disorders
JP2016514671A (ja)	2013-03-15	2016-05-23	シナジーファーマシューティカルズインコーポレイテッド	グアニル酸シクラーゼのアゴニストおよびその使用
BR112015026513A2 (pt)	2013-04-17	2017-07-25	Pfizer	derivados de n-piperidin-3-ilbenzamida para tratar as doenças cardiovasculares
CN105764916B (zh)	2013-06-05	2021-05-18	博士医疗爱尔兰有限公司	鸟苷酸环化酶c的超纯激动剂、制备和使用所述激动剂的方法
MX389591B (es)	2014-08-29	2025-03-20	Tes Pharma S R L	INHIBIDORES DE ACIDO A-AMINO-ß-CARBOXIMUCONICO SEMIALDEHIDO DESCARBOXILASA
WO2016055901A1 (en)	2014-10-08	2016-04-14	Pfizer Inc.	Substituted amide compounds
MX2019004321A (es)	2016-10-14	2019-06-12	Tes Pharma S R L	Inhibidores de la acido alfa-amino-beta-carboximuconico semialdehido descarboxilasa.
CN118496217A (zh)	2018-11-20	2024-08-16	Tes制药有限责任公司	α-氨基-β-羧基己二烯二酸半醛去羧酶的抑制剂
RS66416B1 (sr)	2019-01-18	2025-02-28	Astrazeneca Ab	6'-[[(1s,3s)-3-[[5-(difluorometoksi)-2-pirimidinil]amino]ciklopentil]amino][1(2h),3'-bipiridin]-2-on kao inhibitor pcsk9 i metode njegove primene

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE2064092C2 (de) *	1970-12-28	1983-06-01	Bayer Ag, 5090 Leverkusen	Inhibitoren für Glykosidhydrolasen aus Actinomyceten
DE2347782C3 (de) *	1973-09-22	1979-10-11	Bayer Ag, 5090 Leverkusen	Aminozuckerderivate, Verfahren zu ihrer Herstellung sowie diese Verbindungen enthaltende Arzneimittel
US4062950A (en) *	1973-09-22	1977-12-13	Bayer Aktiengesellschaft	Amino sugar derivatives
US4065557A (en) *	1974-03-21	1977-12-27	Bayer Aktiengesellschaft	Amino sugars and their use in improving the meat:fat ratio in animals
USRE29903E (en)	1975-03-19	1979-02-06	American Cyanamid Company	Antibacterial antibiotics AM31α, AM31β and AM31γ
DE2614393C3 (de) *	1976-04-02	1980-04-03	Bayer Ag, 5090 Leverkusen	Aminozucker-Derivate und diese Verbindungen enthaltende Arzneimittel

1979
- 1979-01-31 CA CA000320579A patent/CA1121290A/en not_active Expired
- 1979-02-07 ZA ZA79528A patent/ZA79528B/xx unknown
- 1979-02-07 AU AU44028/79A patent/AU527318B2/en not_active Ceased
- 1979-02-07 PH PH22174A patent/PH15084A/en unknown
- 1979-02-08 IL IL56626A patent/IL56626A0/xx not_active IP Right Cessation
- 1979-02-08 AR AR275445A patent/AR219150A1/es active
- 1979-02-09 US US06/011,002 patent/US4273765A/en not_active Expired - Lifetime
- 1979-02-12 HU HU79HO2138A patent/HU181442B/hu not_active IP Right Cessation
- 1979-02-12 FR FR7903452A patent/FR2416901A1/fr active Granted
- 1979-02-12 NZ NZ189625A patent/NZ189625A/xx unknown
- 1979-02-12 LU LU80906A patent/LU80906A1/de unknown
- 1979-02-13 ES ES477653A patent/ES477653A1/es not_active Expired
- 1979-02-13 JP JP1443879A patent/JPS54163511A/ja active Granted
- 1979-02-13 NO NO790469A patent/NO153011C/no unknown
- 1979-02-13 MC MC791365A patent/MC1253A1/fr unknown
- 1979-02-13 SE SE7901276A patent/SE7901276L/ not_active Application Discontinuation
- 1979-02-13 IE IE274/79A patent/IE47916B1/en not_active IP Right Cessation
- 1979-02-13 GR GR58344A patent/GR72817B/el unknown
- 1979-02-13 DK DK61179A patent/DK149599C/da active
- 1979-02-13 PT PT7969218A patent/PT69218A/pt unknown
- 1979-02-13 AT AT0108879A patent/AT367451B/de not_active IP Right Cessation
- 1979-02-14 NL NL7901182A patent/NL7901182A/xx not_active Application Discontinuation
- 1979-02-14 DE DE19792905649 patent/DE2905649A1/de not_active Withdrawn
- 1979-02-14 FI FI790486A patent/FI63062C/fi not_active IP Right Cessation
- 1979-02-14 DE DE7979100441T patent/DE2962165D1/de not_active Expired
- 1979-02-14 YU YU348/79A patent/YU41437B/xx unknown
- 1979-02-14 EP EP79100441A patent/EP0003616B1/de not_active Expired

Also Published As

Publication number	Publication date
NO153011C (no)	1986-01-02
DK149599C (da)	1987-06-01
IE790274L (en)	1979-08-14
NZ189625A (en)	1981-05-01
DE2962165D1 (en)	1982-03-25
EP0003616A2 (de)	1979-08-22
US4273765A (en)	1981-06-16
FI63062C (fi)	1983-04-11
AR219150A1 (es)	1980-07-31
FR2416901B1 (cs)	1980-10-24
JPS54163511A (en)	1979-12-26
JPS643877B2 (cs)	1989-01-23
ZA79528B (en)	1980-02-27
LU80906A1 (de)	1980-09-24
EP0003616B1 (de)	1982-02-24
HU181442B (en)	1983-07-28
AU4402879A (en)	1979-08-23
YU34879A (en)	1983-01-21
PH15084A (en)	1982-07-02
FI790486A7 (fi)	1979-08-15
DK61179A (da)	1979-08-15
IL56626A0 (en)	1979-05-31
AU527318B2 (en)	1983-02-24
FI63062B (fi)	1982-12-31
CA1121290A (en)	1982-04-06
EP0003616A3 (en)	1979-09-05
ES477653A1 (es)	1980-03-01
NL7901182A (nl)	1979-08-16
IE47916B1 (en)	1984-07-25
PT69218A (en)	1979-03-01
NO153011B (no)	1985-09-23
ATA108879A (de)	1981-11-15
GR72817B (cs)	1983-12-06
FR2416901A1 (fr)	1979-09-07
DE2905649A1 (de)	1979-08-16
DK149599B (da)	1986-08-04
NO790469L (no)	1979-08-15
AT367451B (de)	1982-07-12
MC1253A1 (fr)	1980-01-14
YU41437B (en)	1987-06-30

Legal Events

Date

Code

Title

Description

1995-02-28

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Publication	Publication Date	Title
SE7901276L (sv)	1979-08-15	Aminosockerderivat
ATE12042T1 (de)	1985-03-15	Aminosaeurederivate und ihre therapeutische verwendung.
ES463632A1 (es)	1978-07-16	Procedimiento de preparacion de derivados de la piperidina.
OA06900A (fr)	1983-04-30	Perfectionnements relatifs à des dérivés de N-arylbenzamides.
IT1064758B (it)	1985-02-25	Composizioni per rivestimenti
NL930107I2 (nl)	1997-02-03	Verbeteringen van of betrekking hebbende op 2,4-digesubstitueerde thiazoolderivaten.
IT1063129B (it)	1985-02-11	Composizioni dolcificanti contenenti arabino..galattano
SE7812232L (sv)	1979-06-02	Korrosionsinhiberande kompositioner
EP0032500A4 (en)	1981-11-24	Preservative compositions.
AR221682A1 (es)	1981-03-13	Procedimiento para la preparacion de derivados de 2(imidazol-4-il,piridil-2-ilo o tiazolil-2-ilo-butil o metiltio-etilamino)-5-(1-naftil-alquilenoxi;1,3-benzodioxolil-alquilenoxi;1,4-benzodioxinilalquilenoxi;1-naftilalquilen;1,3-benzodioxolilalquilen;o 1,4-benzo dioxinilalquilen)-4-pirimidona o 4-pirimidintiona
IL64292A0 (en)	1982-02-28	D-homosteroids,their manufacture and pharmaceutical compositions containing them
JPS5278880A (en)	1977-07-02	Trifluoromethylthioor sulfonyl derivatives from cycloheptadine homologues
NO162343C (no)	1989-12-13	7-acylamino-1-detia-1-oksacefamforbindelser egnet som mellomprodukt for fremstilling av 7beta-acylamino-1-detia-1-oksacefalosporiner.
IT1073249B (it)	1985-04-13	Composizioni per il trattamento di impermeabilizzazione di strutture naturali o artificiali
IL64081A0 (en)	1982-01-31	Novel guanidine derivatives
NO821841L (no)	1982-12-14	Mettede aminocyklitderivater, deres fremstilling og legemiddel inneholdende dem
NL7801261A (nl)	1978-08-08	4-gesubstitueerde aminoderivaten van oleando- mycine.
DK260180A (da)	1980-12-20	Pseudotrisaccharider deres fremstilling og anvendelse som antibakterielle midler
IT7824141A0 (it)	1978-06-02	Procedimento per la depurazione di salamoie.
IT7826443A0 (it)	1978-08-03	Composti di ammido-acrilati per composizioni di rivestimento induribili mediante radiazioni.
BE840449A (fr)	1976-10-07	Composition de protection contre la corrosion
OA07701A (fr)	1985-08-30	Perfectionnements relatifs à des dérivés de benzothiénylglycyl-céphalosporines.
IT7924017A0 (it)	1979-06-29	Perfezionamenti al o relativi al controllo di registro.
IT7822223A0 (it)	1978-04-12	Insieme di pezzi per la realizzazione di arcate di ponte.
FI812698A7 (fi)	1981-09-01	Menetelmä fungisidisten 2-asyyliamino- bentsimidatsolijohdannaisten valmistamiseksi.