SG50414A1 - Therapeutic compounds - Google Patents

Therapeutic compounds

Info

Publication number: SG50414A1
Authority: SG; Singapore
Prior art keywords: pct; alkyl; image; sec; optionally substituted
Prior art date: 1991-09-14

Application number

SG1996000871A

Other languages

English (en)

Inventor

Peter Edward Dr Cross

Alan Dr Stobie

Original Assignee

Pfizer Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1991-09-14

Filing date

1992-09-03

Publication date

1998-07-20

1992-09-03 Application filed by Pfizer Ltd filed Critical Pfizer Ltd

1998-07-20 Publication of SG50414A1 publication Critical patent/SG50414A1/en

Links

150000001875 compounds Chemical class 0.000 title abstract 2
230000001225 therapeutic effect Effects 0.000 title 1
125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 2
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
125000000229 (C1-C4)alkoxy group Chemical group 0.000 abstract 1
125000005913 (C3-C6) cycloalkyl group Chemical group 0.000 abstract 1
208000006545 Chronic Obstructive Pulmonary Disease Diseases 0.000 abstract 1
125000000217 alkyl group Chemical group 0.000 abstract 1
230000001022 anti-muscarinic effect Effects 0.000 abstract 1
208000006673 asthma Diseases 0.000 abstract 1
125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
229940124630 bronchodilator Drugs 0.000 abstract 1
239000000168 bronchodilator agent Substances 0.000 abstract 1
125000001475 halogen functional group Chemical group 0.000 abstract 1
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
125000001424 substituent group Chemical group 0.000 abstract 1
125000001544 thienyl group Chemical group 0.000 abstract 1
125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
- C07C317/44—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
- C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/56—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton containing six-membered aromatic rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
- C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pulmonology (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Psychiatry (AREA)
Addiction (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Pyrrole Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Quinoline Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Plural Heterocyclic Compounds (AREA)

SG1996000871A 1991-09-14 1992-09-03 Therapeutic compounds SG50414A1 (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB919119705A GB9119705D0 (en)	1991-09-14	1991-09-14	Therapeutic compounds

Publications (1)

Publication Number	Publication Date
SG50414A1 true SG50414A1 (en)	1998-07-20

Family

ID=10701448

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SG1996000871A SG50414A1 (en)	1991-09-14	1992-09-03	Therapeutic compounds

Country Status (31)

Country	Link
US (1)	US5543419A (fr)
EP (1)	EP0603229B1 (fr)
JP (2)	JP2672030B2 (fr)
KR (1)	KR0135784B1 (fr)
CN (1)	CN1037269C (fr)
AT (1)	ATE167187T1 (fr)
AU (1)	AU659487B2 (fr)
BR (1)	BR9206499A (fr)
CA (1)	CA2116356C (fr)
CZ (1)	CZ281752B6 (fr)
DE (1)	DE69225897T2 (fr)
DK (1)	DK0603229T3 (fr)
EG (1)	EG20072A (fr)
ES (1)	ES2116343T3 (fr)
FI (1)	FI114707B (fr)
GB (1)	GB9119705D0 (fr)
GR (1)	GR3027667T3 (fr)
HU (1)	HU220594B1 (fr)
IL (1)	IL103078A (fr)
MX (1)	MX9205221A (fr)
MY (1)	MY108602A (fr)
NO (1)	NO305397B1 (fr)
NZ (1)	NZ244324A (fr)
PL (1)	PL170627B1 (fr)
PT (1)	PT100863B (fr)
RU (1)	RU2117669C1 (fr)
SG (1)	SG50414A1 (fr)
TW (1)	TW251285B (fr)
UA (1)	UA42686C2 (fr)
WO (1)	WO1993006098A1 (fr)
ZA (1)	ZA926939B (fr)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
PT785198E (pt) *	1996-01-19	2000-11-30	Lonza Ag	Processo para a producao de 3-quinuclidinol opticamente activo.
CZ54498A3 (cs) *	1997-03-07	1998-11-11	Lonza Ag	Katalyzátorová směs na bázi amorfního částečně dehydratovaného hydroxidu zirkoničitého a způsob její výroby a použití
DE69833665T2 (de) *	1997-08-08	2006-11-09	Duke University	Zusammensetzungen zur vereinfachung von chirurgischen verfahren
US6711436B1 (en)	1997-08-08	2004-03-23	Duke University	Compositions, apparatus and methods for facilitating surgical procedures
ES2165768B1 (es)	1999-07-14	2003-04-01	Almirall Prodesfarma Sa	Nuevos derivados de quinuclidina y composiciones farmaceuticas que los contienen.
HUP0303529A3 (en) *	2000-12-22	2008-03-28	Almirall Ag	New quinuclidine carbamate derivatives, process for their preparation and pharmaceutical compositions containing them and their use
CN1250545C (zh)	2000-12-28	2006-04-12	阿尔米雷尔普罗迪斯制药有限公司	新的奎宁环衍生物类及含有这类衍生物的药物组合物
GB0424284D0 (en) *	2004-11-02	2004-12-01	Novartis Ag	Organic compounds
DE102004057995A1 (de) *	2004-12-01	2006-06-08	Wacker Chemie Ag	Verfahren zur Herstellung von α,α-Dialkyl-α-Hydroxymethyl-Carbonsäurederivaten
ES2298049B1 (es) *	2006-07-21	2009-10-20	Laboratorios Almirall S.A.	Procedimiento para fabricar bromuro de 3(r)-(2-hidroxi-2,2-ditien-2-ilacetoxi)-1-(3-fenoxipropil)-1-azoniabiciclo (2.2.2) octano.
EP2114972A2 (fr) *	2006-12-13	2009-11-11	Gilead Sciences, Inc.	Monophosphates utilisés comme promédicaments mutuels d'antagonistes des récepteurs muscariniques et de beta-agonistes dans le traitement de la b.p.c.o. et de la bronchite chronique
EP2100599A1 (fr)	2008-03-13	2009-09-16	Laboratorios Almirall, S.A.	Composition à inhaler comprenant aclidinium pour le traitement de l'asthme et de maladies respiratoires obstructives chroniques
EP2100598A1 (fr)	2008-03-13	2009-09-16	Laboratorios Almirall, S.A.	Composition à inhaler comprenant aclidinium pour le traitement de l'asthme et de maladies respiratoires obstructives chroniques
EP2510928A1 (fr)	2011-04-15	2012-10-17	Almirall, S.A.	Aclidinium pour l'amélioration du sommeil des patients avec des maldadies respiratoires

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4843074A (en) *	1988-05-17	1989-06-27	Marion Laboratories, Inc.	1-azabicyclo[2.2.2]octan-3-yl 2-aryl-3-azacyclo-2-hydroxypropionates and their quaternary salts
GB8923590D0 (en) *	1989-10-19	1989-12-06	Pfizer Ltd	Antimuscarinic bronchodilators

1991
- 1991-09-14 GB GB919119705A patent/GB9119705D0/en active Pending
1992
- 1992-09-03 KR KR1019940700816A patent/KR0135784B1/ko not_active Expired - Fee Related
- 1992-09-03 CZ CS923953A patent/CZ281752B6/cs not_active IP Right Cessation
- 1992-09-03 WO PCT/EP1992/002067 patent/WO1993006098A1/fr not_active Ceased
- 1992-09-03 CA CA002116356A patent/CA2116356C/fr not_active Expired - Fee Related
- 1992-09-03 DK DK92918526T patent/DK0603229T3/da active
- 1992-09-03 JP JP5505734A patent/JP2672030B2/ja not_active Expired - Fee Related
- 1992-09-03 DE DE69225897T patent/DE69225897T2/de not_active Expired - Fee Related
- 1992-09-03 AU AU24823/92A patent/AU659487B2/en not_active Ceased
- 1992-09-03 PL PL92302771A patent/PL170627B1/pl unknown
- 1992-09-03 UA UA94005520A patent/UA42686C2/uk unknown
- 1992-09-03 HU HU9400729A patent/HU220594B1/hu not_active IP Right Cessation
- 1992-09-03 AT AT92918526T patent/ATE167187T1/de not_active IP Right Cessation
- 1992-09-03 RU RU94019411/04A patent/RU2117669C1/ru not_active IP Right Cessation
- 1992-09-03 BR BR9206499A patent/BR9206499A/pt not_active Application Discontinuation
- 1992-09-03 ES ES92918526T patent/ES2116343T3/es not_active Expired - Lifetime
- 1992-09-03 EP EP92918526A patent/EP0603229B1/fr not_active Expired - Lifetime
- 1992-09-03 SG SG1996000871A patent/SG50414A1/en unknown
- 1992-09-03 US US08/204,260 patent/US5543419A/en not_active Expired - Fee Related
- 1992-09-07 IL IL10307892A patent/IL103078A/en not_active IP Right Cessation
- 1992-09-10 TW TW081107184A patent/TW251285B/zh active
- 1992-09-11 PT PT100863A patent/PT100863B/pt active IP Right Grant
- 1992-09-11 ZA ZA926939A patent/ZA926939B/xx unknown
- 1992-09-11 MX MX9205221A patent/MX9205221A/es not_active IP Right Cessation
- 1992-09-14 EG EG54292A patent/EG20072A/xx active
- 1992-09-14 MY MYPI92001642A patent/MY108602A/en unknown
- 1992-09-14 CN CN92110746A patent/CN1037269C/zh not_active Expired - Fee Related
- 1992-09-14 NZ NZ244324A patent/NZ244324A/en unknown
1994
- 1994-03-11 FI FI941170A patent/FI114707B/fi not_active IP Right Cessation
- 1994-03-14 NO NO940905A patent/NO305397B1/no unknown
1997
- 1997-02-18 JP JP9033807A patent/JP2955533B2/ja not_active Expired - Fee Related
1998
- 1998-08-19 GR GR980401846T patent/GR3027667T3/el unknown

Also Published As

Publication number	Publication date
JPH06510991A (ja)	1994-12-08
FI114707B (fi)	2004-12-15
EG20072A (en)	1999-06-30
CA2116356C (fr)	1998-03-31
CZ281752B6 (cs)	1997-01-15
EP0603229B1 (fr)	1998-06-10
JPH09315970A (ja)	1997-12-09
KR0135784B1 (ko)	1998-04-23
NZ244324A (en)	1993-12-23
MX9205221A (es)	1993-03-01
GR3027667T3 (en)	1998-11-30
JP2672030B2 (ja)	1997-11-05
ATE167187T1 (de)	1998-06-15
HU220594B1 (hu)	2002-03-28
JP2955533B2 (ja)	1999-10-04
FI941170A0 (fi)	1994-03-11
WO1993006098A1 (fr)	1993-04-01
BR9206499A (pt)	1995-11-21
MY108602A (en)	1996-10-31
CN1070911A (zh)	1993-04-14
IL103078A0 (en)	1993-02-21
UA42686C2 (uk)	2001-11-15
DE69225897T2 (de)	1998-10-15
CN1037269C (zh)	1998-02-04
NO940905D0 (no)	1994-03-14
IL103078A (en)	1996-07-23
GB9119705D0 (en)	1991-10-30
NO305397B1 (no)	1999-05-25
AU659487B2 (en)	1995-05-18
DK0603229T3 (da)	1998-10-12
AU2482392A (en)	1993-04-27
PT100863A (pt)	1993-10-29
EP0603229A1 (fr)	1994-06-29
ZA926939B (en)	1994-03-11
ES2116343T3 (es)	1998-07-16
CA2116356A1 (fr)	1993-04-01
HU9400729D0 (en)	1994-06-28
NO940905L (no)	1994-03-14
US5543419A (en)	1996-08-06
RU2117669C1 (ru)	1998-08-20
CZ395392A3 (en)	1994-07-13
PL170627B1 (en)	1997-01-31
DE69225897D1 (de)	1998-07-16
PT100863B (pt)	1999-07-30
HUT66772A (en)	1994-12-28
FI941170L (fi)	1994-03-11
TW251285B (fr)	1995-07-11

Publication	Publication Date	Title
EG20072A (en)	1999-06-30	Therapeutic compounds
GB9524157D0 (en)	1996-01-24	Therapeutic agents
GR3034769T3 (en)	2001-02-28	Triazole antifungal agents.
ATE185555T1 (de)	1999-10-15	Monoamin oxydase b hemmende verbidungen verfahren zu ihrer herstellung un ihrer verwendung
PH30660A (en)	1997-09-16	Therapeutic agents
RU94019411A (ru)	1995-11-27	Эфиры хинук лидина, промежуточные соединения для их синтеза, фармацевтическая композиция и способ лечения
NO944923L (no)	1995-06-22	Hemming av vektökning eller indusering av vekttap
PL312582A1 (en)	1996-04-29	Use of cephem derivatives as antimetastatic means
NO951798L (no)	1995-05-31	Terapeutiske midler