SI1354875T1 - Method for synthesis of (2S,3aS,7aS)-perhydroindole-2-carboxylic acid and esters thereof; and use in the synthesis of perindopril - Google Patents
Method for synthesis of (2S,3aS,7aS)-perhydroindole-2-carboxylic acid and esters thereof; and use in the synthesis of perindoprilInfo
- Publication number
- SI1354875T1 SI1354875T1 SI200330011T SI200330011T SI1354875T1 SI 1354875 T1 SI1354875 T1 SI 1354875T1 SI 200330011 T SI200330011 T SI 200330011T SI 200330011 T SI200330011 T SI 200330011T SI 1354875 T1 SI1354875 T1 SI 1354875T1
- Authority
- SI
- Slovenia
- Prior art keywords
- synthesis
- perhydroindole
- perindopril
- esters
- carboxylic acid
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Indole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP03291157A EP1354875B1 (fr) | 2003-05-19 | 2003-05-19 | Nouveau procédé de synthèse de l'acide (2S, 3aS, 7aS)-perhydroindole-2-carboxilique et de ses esters, et application à la synthèse du perindopril |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SI1354875T1 true SI1354875T1 (en) | 2005-02-28 |
Family
ID=28459641
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SI200330011T SI1354875T1 (en) | 2003-05-19 | 2003-05-19 | Method for synthesis of (2S,3aS,7aS)-perhydroindole-2-carboxylic acid and esters thereof; and use in the synthesis of perindopril |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP1354875B1 (da) |
| AR (1) | AR044392A1 (da) |
| AT (1) | ATE283258T1 (da) |
| DE (1) | DE60300168T2 (da) |
| DK (1) | DK1354875T3 (da) |
| ES (1) | ES2233914T3 (da) |
| MY (1) | MY136639A (da) |
| PT (1) | PT1354875E (da) |
| SI (1) | SI1354875T1 (da) |
| WO (1) | WO2004103969A1 (da) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100391945C (zh) * | 2005-05-31 | 2008-06-04 | 浙江大学 | 一种s-(-)-吲哚啉-2-羧酸的合成方法 |
| WO2014012851A1 (en) | 2012-07-17 | 2014-01-23 | F. Hoffmann-La Roche Ag | Arylethynyl derivatives |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ202903A (en) * | 1981-12-29 | 1988-01-08 | Hoechst Ag | 1-- pe pyrrol-2-yl-carboxylic acid derivatives and pharmaceutical compositions |
| FR2620703B1 (fr) * | 1987-09-17 | 1991-10-04 | Adir | Procede de synthese industrielle de l'acide perhydroindole carboxylique - 2(2s, 3as, 7as). application a la synthese de carboxyalkyl dipeptides |
-
2003
- 2003-05-19 PT PT03291157T patent/PT1354875E/pt unknown
- 2003-05-19 AT AT03291157T patent/ATE283258T1/de active
- 2003-05-19 DE DE60300168T patent/DE60300168T2/de not_active Expired - Lifetime
- 2003-05-19 SI SI200330011T patent/SI1354875T1/xx unknown
- 2003-05-19 EP EP03291157A patent/EP1354875B1/fr not_active Expired - Lifetime
- 2003-05-19 DK DK03291157T patent/DK1354875T3/da active
- 2003-05-19 ES ES03291157T patent/ES2233914T3/es not_active Expired - Lifetime
-
2004
- 2004-05-19 MY MYPI20041884A patent/MY136639A/en unknown
- 2004-05-19 WO PCT/FR2004/001225 patent/WO2004103969A1/fr not_active Ceased
- 2004-05-19 AR ARP040101725A patent/AR044392A1/es not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| DE60300168D1 (de) | 2004-12-30 |
| AR044392A1 (es) | 2005-09-14 |
| ES2233914T3 (es) | 2005-06-16 |
| WO2004103969A1 (fr) | 2004-12-02 |
| ATE283258T1 (de) | 2004-12-15 |
| EP1354875A1 (fr) | 2003-10-22 |
| DE60300168T2 (de) | 2005-12-01 |
| PT1354875E (pt) | 2005-03-31 |
| EP1354875B1 (fr) | 2004-11-24 |
| MY136639A (en) | 2008-11-28 |
| DK1354875T3 (da) | 2005-03-14 |
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