SK90295A3 - Process for preparation of taxane derivatives and their beta-lactam intermediate products - Google Patents

Process for preparation of taxane derivatives and their beta-lactam intermediate products Download PDF

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Publication number
SK90295A3
SK90295A3 SK902-95A SK90295A SK90295A3 SK 90295 A3 SK90295 A3 SK 90295A3 SK 90295 A SK90295 A SK 90295A SK 90295 A3 SK90295 A3 SK 90295A3
Authority
SK
Slovakia
Prior art keywords
radical
carbon atoms
hydrogen
tert
phenyl
Prior art date
Application number
SK902-95A
Other languages
English (en)
Slovak (sk)
Inventor
Iwao Ojima
Original Assignee
On The Research Foundation Of
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by On The Research Foundation Of filed Critical On The Research Foundation Of
Publication of SK90295A3 publication Critical patent/SK90295A3/sk

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Epoxy Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Plural Heterocyclic Compounds (AREA)
SK902-95A 1993-02-01 1994-01-28 Process for preparation of taxane derivatives and their beta-lactam intermediate products SK90295A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US1192293A 1993-02-01 1993-02-01
PCT/US1994/000669 WO1994018164A1 (en) 1993-02-01 1994-01-28 PROCESS FOR PREPARATION OF TAXANE DERIVATIVES AND β-LACTAM INTERMEDIATES THEREFOR

Publications (1)

Publication Number Publication Date
SK90295A3 true SK90295A3 (en) 1996-05-08

Family

ID=21752542

Family Applications (1)

Application Number Title Priority Date Filing Date
SK902-95A SK90295A3 (en) 1993-02-01 1994-01-28 Process for preparation of taxane derivatives and their beta-lactam intermediate products

Country Status (17)

Country Link
EP (1) EP0681568B1 (de)
JP (1) JP3492367B2 (de)
KR (1) KR960700226A (de)
AT (1) ATE334115T1 (de)
AU (1) AU687782B2 (de)
CA (1) CA2154071C (de)
CZ (1) CZ192195A3 (de)
DE (1) DE69434801T2 (de)
FI (1) FI953645L (de)
MX (1) MX9400806A (de)
NO (1) NO953011L (de)
NZ (1) NZ261529A (de)
PL (1) PL310075A1 (de)
RU (1) RU95116366A (de)
SK (1) SK90295A3 (de)
WO (1) WO1994018164A1 (de)
ZA (1) ZA94128B (de)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5710287A (en) 1991-09-23 1998-01-20 Florida State University Taxanes having an amino substituted side-chain and pharmaceutical compositions containing them
FR2698871B1 (fr) 1992-12-09 1995-02-24 Rhone Poulenc Rorer Sa Nouveau taxoïdes, leur préparation et les compositions pharmaceutiques qui les contiennent.
US6593482B2 (en) 1993-02-01 2003-07-15 Aventis Pharma S.A. Methods for preparing new taxoids and pharmaceutical compositions containing them
US6232477B1 (en) 1996-03-25 2001-05-15 Aventis Pharma S.A. Methods of preparing new taxoids and pharmaceutical compositions containing them
US6040466A (en) * 1996-03-25 2000-03-21 Rhone Poulenc Rorer Sa Taxoids, their preparation and pharmaceutical compositions containing them
FR2732340B1 (fr) * 1995-03-27 1997-04-30 Rhone Poulenc Rorer Sa Nouveaux taxoides, leur preparation et les compositions pharmaceutiques qui les contiennent
CA2120221A1 (en) * 1993-04-23 1994-10-24 Allan W. Rey N-substituted 2-azetidinones
US5677470A (en) * 1994-06-28 1997-10-14 Tanabe Seiyaku Co., Ltd. Baccatin derivatives and processes for preparing the same
CA2162759A1 (en) * 1994-11-17 1996-05-18 Kenji Tsujihara Baccatin derivatives and processes for preparing the same
US5847170A (en) * 1995-03-27 1998-12-08 Rhone-Poulenc Rorer, S.A. Taxoids, their preparation and pharmaceutical compositions containing them
MA23823A1 (fr) * 1995-03-27 1996-10-01 Aventis Pharma Sa Nouveaux taxoides, leur preparation et les compositions qui les contiennent
US6372780B2 (en) 1995-03-27 2002-04-16 Aventis Pharma S.A. Methods of treating cell lines expressing multidrug resistance P-glycoprotein
EP0944594A4 (de) * 1996-12-13 2000-05-03 Lilly Co Eli Inhibitoren der enzymatischen aktiviät von psa
US5811452A (en) * 1997-01-08 1998-09-22 The Research Foundation Of State University Of New York Taxoid reversal agents for drug-resistance in cancer chemotherapy and pharmaceutical compositions thereof
US6156789A (en) * 1998-03-17 2000-12-05 Rhone-Poulenc Rorer S.A. Method for treating abnormal cell proliferation in the brain
US6916942B2 (en) 2000-02-03 2005-07-12 Bristol-Myers Squibb Company Process for the preparation of C-4 carbonate taxanes
BRPI0611954A2 (pt) 2005-06-10 2009-04-28 Univ Florida State Res Found processos para a produÇço de compostos de anel fundido policÍclico
KR101333438B1 (ko) * 2005-06-10 2013-11-27 플로리다 스테이트 유니버시티 리서치 파운데이션, 인크 도세탁셀의 제조 방법
KR101712231B1 (ko) 2009-10-29 2017-03-03 아벤티스 파마 소시에떼아노님 카바지탁셀의 신규한 항종양 용도
HK1201466A1 (en) 2011-09-21 2015-09-04 干细胞医药有限公司 Beta-lactam compounds for treating diabetes
US9345691B2 (en) 2011-09-21 2016-05-24 Stem Cell Medicine Ltd. Beta-lactam compounds for enhancing T cell-mediated immune responses
CN102408356A (zh) * 2011-09-28 2012-04-11 北京东方协和医药生物技术有限公司 一种多西他赛手性侧链中间体的制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5175315A (en) * 1989-05-31 1992-12-29 Florida State University Method for preparation of taxol using β-lactam
CA2071160A1 (en) * 1991-07-31 1993-02-01 Vittorio Farina Asymmetric synthesis of taxol side chain
HU225474B1 (en) * 1991-09-23 2006-12-28 Univ Florida State New 10-desacetoxytaxol derivatives, pharmaceutical derivatives containing them and procedure for preparing them
EP0884314B1 (de) * 1991-09-23 2004-01-21 Florida State University Metallalkoxide
US5229526A (en) * 1991-09-23 1993-07-20 Florida State University Metal alkoxides

Also Published As

Publication number Publication date
EP0681568B1 (de) 2006-07-26
AU6031394A (en) 1994-08-29
KR960700226A (ko) 1996-01-19
ZA94128B (en) 1994-08-19
WO1994018164A1 (en) 1994-08-18
NO953011L (no) 1995-09-21
NO953011D0 (no) 1995-07-31
ATE334115T1 (de) 2006-08-15
FI953645A0 (fi) 1995-07-31
FI953645A7 (fi) 1995-09-27
PL310075A1 (en) 1995-11-27
JP3492367B2 (ja) 2004-02-03
DE69434801T2 (de) 2007-08-09
DE69434801D1 (de) 2006-09-07
RU95116366A (ru) 1997-06-10
MX9400806A (es) 1994-08-31
FI953645L (fi) 1995-09-27
CA2154071C (en) 2005-06-28
CA2154071A1 (en) 1994-08-18
CZ192195A3 (en) 1995-12-13
EP0681568A1 (de) 1995-11-15
AU687782B2 (en) 1998-03-05
JPH08506339A (ja) 1996-07-09
NZ261529A (en) 1997-05-26

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