SU683624A3 - Способ получени производных тиено-(3,2-с)пиридина или их солей - Google Patents

Способ получени производных тиено-(3,2-с)пиридина или их солей

Info

Publication number: SU683624A3
Authority: SU; USSR - Soviet Union
Prior art keywords: thieno; salts; preparation; pyridine derivatives; alkyl
Prior art date: 1976-02-09

Application number

SU772451699A

Other languages

English (en)

Russian (ru)

Inventor

Трокслер Франц

Вискотт Эрик

Original Assignee

Сандос Аг (Фирма)

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1976-02-09

Filing date

1977-02-09

Publication date

1979-08-30

1977-02-09 Application filed by Сандос Аг (Фирма) filed Critical Сандос Аг (Фирма)

1979-08-30 Application granted granted Critical

1979-08-30 Publication of SU683624A3 publication Critical patent/SU683624A3/ru

Links

150000003839 salts Chemical class 0.000 title description 5
238000000034 method Methods 0.000 title description 3
238000002360 preparation method Methods 0.000 title description 2
150000003222 pyridines Chemical class 0.000 title 1
HEDRZPFGACZZDS-UHFFFAOYSA-N Chloroform Chemical compound ClC(Cl)Cl HEDRZPFGACZZDS-UHFFFAOYSA-N 0.000 description 6
JUJWROOIHBZHMG-UHFFFAOYSA-N Pyridine Chemical compound C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 description 4
125000000217 alkyl group Chemical group 0.000 description 4
150000001875 compounds Chemical class 0.000 description 4
WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical compound [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 description 3
YMWUJEATGCHHMB-UHFFFAOYSA-N Dichloromethane Chemical compound ClCCl YMWUJEATGCHHMB-UHFFFAOYSA-N 0.000 description 3
HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 3
229910052801 chlorine Inorganic materials 0.000 description 3
239000000460 chlorine Substances 0.000 description 3
229910052731 fluorine Inorganic materials 0.000 description 3
239000011737 fluorine Substances 0.000 description 3
QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 description 2
ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 description 2
RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 2
PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical compound FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 description 2
CSNNHWWHGAXBCP-UHFFFAOYSA-L Magnesium sulfate Chemical compound [Mg+2].[O-][S+2]([O-])([O-])[O-] CSNNHWWHGAXBCP-UHFFFAOYSA-L 0.000 description 2
WYURNTSHIVDZCO-UHFFFAOYSA-N Tetrahydrofuran Chemical compound C1CCOC1 WYURNTSHIVDZCO-UHFFFAOYSA-N 0.000 description 2
239000002253 acid Substances 0.000 description 2
150000008064 anhydrides Chemical class 0.000 description 2
GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Substances BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 description 2
229910052794 bromium Inorganic materials 0.000 description 2
239000001257 hydrogen Substances 0.000 description 2
229910052739 hydrogen Inorganic materials 0.000 description 2
125000004435 hydrogen atom Chemical class [H]* 0.000 description 2
UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Natural products COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 description 2
FALRKNHUBBKYCC-UHFFFAOYSA-N 2-(chloromethyl)pyridine-3-carbonitrile Chemical compound ClCC1=NC=CC=C1C#N FALRKNHUBBKYCC-UHFFFAOYSA-N 0.000 description 1
KZBUYRJDOAKODT-UHFFFAOYSA-N Chlorine Chemical compound ClCl KZBUYRJDOAKODT-UHFFFAOYSA-N 0.000 description 1
229960000583 acetic acid Drugs 0.000 description 1
125000004093 cyano group Chemical group *C#N 0.000 description 1
125000001153 fluoro group Chemical group F* 0.000 description 1
239000012362 glacial acetic acid Substances 0.000 description 1
238000002955 isolation Methods 0.000 description 1
125000001449 isopropyl group Chemical group [H]C([H])([H])C([H])(*)C([H])([H])[H] 0.000 description 1
229910052943 magnesium sulfate Inorganic materials 0.000 description 1
235000019341 magnesium sulphate Nutrition 0.000 description 1
238000004519 manufacturing process Methods 0.000 description 1
238000002844 melting Methods 0.000 description 1
230000008018 melting Effects 0.000 description 1
239000000203 mixture Substances 0.000 description 1
125000000896 monocarboxylic acid group Chemical group 0.000 description 1
ODBQLAOJWDJIHA-UHFFFAOYSA-N n-[bis(dimethylamino)phosphoryl]-n-methylmethanamine;chloroform Chemical compound ClC(Cl)Cl.CN(C)P(=O)(N(C)C)N(C)C ODBQLAOJWDJIHA-UHFFFAOYSA-N 0.000 description 1
125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 description 1
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 description 1
238000000926 separation method Methods 0.000 description 1
239000002904 solvent Substances 0.000 description 1
229940014800 succinic anhydride Drugs 0.000 description 1
YLQBMQCUIZJEEH-UHFFFAOYSA-N tetrahydrofuran Natural products C=1C=COC=1 YLQBMQCUIZJEEH-UHFFFAOYSA-N 0.000 description 1
GKTQKQTXHNUFSP-UHFFFAOYSA-N thieno[3,4-c]pyrrole-4,6-dione Chemical compound S1C=C2C(=O)NC(=O)C2=C1 GKTQKQTXHNUFSP-UHFFFAOYSA-N 0.000 description 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
General Health & Medical Sciences (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Diabetes (AREA)
Hematology (AREA)
Obesity (AREA)
Vascular Medicine (AREA)
Urology & Nephrology (AREA)
Emergency Medicine (AREA)
Endocrinology (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

SU772451699A 1976-02-09 1977-02-09 Способ получени производных тиено-(3,2-с)пиридина или их солей SU683624A3 (ru)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
CH153076A CH619956A5 (en)	1976-02-09	1976-02-09	Process for the preparation of novel thieno[3,2-c]pyridine derivatives

Publications (1)

Publication Number	Publication Date
SU683624A3 true SU683624A3 (ru)	1979-08-30

Family

ID=4212597

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SU772451699A SU683624A3 (ru)	1976-02-09	1977-02-09	Способ получени производных тиено-(3,2-с)пиридина или их солей

Country Status (21)

Country	Link
JP (1)	JPS5297995A (fr)
AT (1)	AT363088B (fr)
AU (1)	AU512534B2 (fr)
BE (1)	BE851180A (fr)
CA (1)	CA1078844A (fr)
CH (2)	CH619956A5 (fr)
DE (1)	DE2703888A1 (fr)
DK (1)	DK42077A (fr)
ES (1)	ES455701A1 (fr)
FI (1)	FI770320A7 (fr)
FR (1)	FR2340320A1 (fr)
GB (1)	GB1570328A (fr)
IE (1)	IE44438B1 (fr)
IL (1)	IL51396A (fr)
NL (1)	NL7701179A (fr)
NZ (1)	NZ183267A (fr)
PH (1)	PH13659A (fr)
PT (1)	PT66166B (fr)
SE (1)	SE7700962L (fr)
SU (1)	SU683624A3 (fr)
ZA (1)	ZA77742B (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS53153946U (fr) *	1977-05-10	1978-12-04
FR2452490A1 (fr) *	1979-03-30	1980-10-24	Sanofi Sa	Nouveaux derives des thieno(2,3-c) et 3,2-c) pyridines, leur procede de preparation et leur application therapeutique
GB0525164D0 (en)	2005-12-09	2006-01-18	Xention Discovery Ltd	Compounds

1976
- 1976-02-09 CH CH153076A patent/CH619956A5/de not_active IP Right Cessation
1977
- 1977-01-31 SE SE7700962A patent/SE7700962L/xx not_active Application Discontinuation
- 1977-01-31 FI FI770320A patent/FI770320A7/fi not_active Application Discontinuation
- 1977-01-31 DE DE19772703888 patent/DE2703888A1/de not_active Withdrawn
- 1977-02-01 DK DK42077A patent/DK42077A/da unknown
- 1977-02-04 NL NL7701179A patent/NL7701179A/xx not_active Application Discontinuation
- 1977-02-07 ES ES455701A patent/ES455701A1/es not_active Expired
- 1977-02-07 IL IL51396A patent/IL51396A/xx unknown
- 1977-02-07 PT PT66166A patent/PT66166B/fr unknown
- 1977-02-07 IE IE254/77A patent/IE44438B1/en unknown
- 1977-02-07 CA CA271,181A patent/CA1078844A/fr not_active Expired
- 1977-02-07 NZ NZ183267A patent/NZ183267A/xx unknown
- 1977-02-07 PH PH19422A patent/PH13659A/en unknown
- 1977-02-07 BE BE174734A patent/BE851180A/fr unknown
- 1977-02-08 FR FR7703432A patent/FR2340320A1/fr active Granted
- 1977-02-08 GB GB5104/77A patent/GB1570328A/en not_active Expired
- 1977-02-08 JP JP1219677A patent/JPS5297995A/ja active Pending
- 1977-02-08 AT AT0080977A patent/AT363088B/de not_active IP Right Cessation
- 1977-02-09 SU SU772451699A patent/SU683624A3/ru active
- 1977-02-09 AU AU22136/77A patent/AU512534B2/en not_active Expired
- 1977-02-09 ZA ZA00770742A patent/ZA77742B/xx unknown
1980
- 1980-01-30 CH CH75580A patent/CH622796A5/de not_active IP Right Cessation

Also Published As

Publication number	Publication date
FI770320A7 (fr)	1977-08-10
CH619956A5 (en)	1980-10-31
ES455701A1 (es)	1978-04-16
DK42077A (da)	1977-08-10
CA1078844A (fr)	1980-06-03
IE44438L (en)	1977-08-09
NL7701179A (nl)	1977-08-11
PT66166A (fr)	1977-03-01
NZ183267A (en)	1979-04-26
AT363088B (de)	1981-07-10
IE44438B1 (en)	1981-12-02
AU2213677A (en)	1978-08-17
ZA77742B (en)	1978-09-27
BE851180A (fr)	1977-08-08
IL51396A0 (en)	1977-04-29
GB1570328A (en)	1980-06-25
ATA80977A (de)	1980-12-15
PH13659A (en)	1980-08-21
FR2340320B1 (fr)	1980-03-14
AU512534B2 (en)	1980-10-16
DE2703888A1 (de)	1977-08-11
IL51396A (en)	1980-02-29
JPS5297995A (en)	1977-08-17
SE7700962L (sv)	1977-08-10
FR2340320A1 (fr)	1977-09-02
CH622796A5 (en)	1981-04-30
PT66166B (fr)	1978-10-13

Publication	Publication Date	Title
US4216167A (en)	1980-08-05	1,3 Diaminopropane derivatives
SU873879A3 (ru)	1981-10-15	Способ получени производных бензимидазола или их солей
US4816479A (en)	1989-03-28	Xanthone derivatives and process for producing the same
SU625610A3 (ru)	1978-09-25	Способ получени 3,3,5,5тетрахлорфенол-3,4,5,6тетрабромсульфофталеина или 3,3-дибром -5,5-дихлорфенол3,4,5,6-тетрахлорсульфофталеина
DD219769A5 (de)	1985-03-13	Verfahren zur herstellung von 1,3-dioxan-5-yl-alkansaeure-derivaten
JPS6339868A (ja)	1988-02-20	ジ低級アルキルフエノ−ル誘導体
JPH0253762A (ja)	1990-02-22	新規スルホンアミドおよびこれを含有する、物質代謝機能病および血行障害治療薬
SU537626A3 (ru)	1976-11-30	Способ получени производных алканоламина
JPH01211567A (ja)	1989-08-24	新規なスルホンアミド化合物
CA1093068A (fr)	1981-01-06	Traduction non-disponible
US4658055A (en)	1987-04-14	Method for manufacture of 7-(2,5-dioxocyclopentyl)heptanoic acid derivative
SU683624A3 (ru)	1979-08-30	Способ получени производных тиено-(3,2-с)пиридина или их солей
SU1342415A3 (ru)	1987-09-30	Способ получени производных пиридазина
SU648087A3 (ru)	1979-02-15	Способ получени сульфона
US3933826A (en)	1976-01-20	Protoberberine derivatives
US5359076A (en)	1994-10-25	Cyclic aminophenylacetic acid derivatives, process for preparing the same and immune response modulator having the same as an effective ingredient
US4439436A (en)	1984-03-27	1,3-Dioxolo(4,5-G)quinoline compounds
EP0116628B1 (fr)	1989-01-18	1-acyl-3-pyridylmethylguanidines et leur utilisation comme agents anti-hypertensifs
SU718011A3 (ru)	1980-02-25	Способ получени производных 4-фенилтиено-(2,3-с)пиперидина или их солей
US3822278A (en)	1974-07-02	N-cyclopropyl-pyridyl carboxamide derivatives
NO130329B (fr)	1974-08-12
JPS6014032B2 (ja)	1985-04-11	５‐フエネチル‐２‐オキサゾリドン誘導体およびその製法
DE2922231C2 (fr)	1988-10-06
US4355166A (en)	1982-10-19	Quinuclidinic ester and derivatives of phenoxycarboxylic acids
US4142048A (en)	1979-02-27	Production of tris-(2-hydroxyaryl) esters of cyanuric acid