TR200002462T2 - Kristalimsi organik bileşiklerin dengeli şekilli parçacıkları - Google Patents
Kristalimsi organik bileşiklerin dengeli şekilli parçacıklarıInfo
- Publication number
- TR200002462T2 TR200002462T2 TR2000/02462T TR200002462T TR200002462T2 TR 200002462 T2 TR200002462 T2 TR 200002462T2 TR 2000/02462 T TR2000/02462 T TR 2000/02462T TR 200002462 T TR200002462 T TR 200002462T TR 200002462 T2 TR200002462 T2 TR 200002462T2
- Authority
- TR
- Turkey
- Prior art keywords
- balanced
- particles
- organic compounds
- present
- shaped particles
- Prior art date
Links
- 239000002245 particle Substances 0.000 title abstract 7
- 150000002894 organic compounds Chemical class 0.000 title abstract 3
- 238000002425 crystallisation Methods 0.000 abstract 2
- 230000008025 crystallization Effects 0.000 abstract 2
- 239000004005 microsphere Substances 0.000 abstract 2
- 239000007787 solid Substances 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 238000013268 sustained release Methods 0.000 abstract 1
- 239000012730 sustained-release form Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/30—Oestrogens
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
- Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
- Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
- Y10T428/2989—Microcapsule with solid core [includes liposome]
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Diabetes (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Steroid Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Processes Of Treating Macromolecular Substances (AREA)
Abstract
Mevcut bulusta, alotropik organik bilesiklerin depolama dengeli, sekilli parçaciklari saglanir. Mevcut bulusun parçaciklari arzu edilen uygulamaya göre sekillendirilebilir. Bu tür parçaciklarin tercih edilen sekilleri mikrosferler, özellikle de yaklasik 1 ila yaklasik 1,000 mikronluk çapa sahip olan mikrosferlerdir. Mevcut bulusun dengeli sekilli parçaciklari özellikle farmasötik formülasyonlarin, özellikle de sürekli salim ve tekbiçimli biyo yararlilik arzu edilen durumlarda imalati için uygundur. Depolama dengeli parçaciklar, alotropik organik bilesiklerin bir kati hal kristallestirilmesi ile olusturulurlar. Mevcut bulusun kati hal kristallestirme islemi ile orjinal parçacik boyutlari bozulmadan veya kaybolmadan sözkonusu alotropik bilesigin depolama dengeli kristalimsi bir halinin elde edilmesi için bir bir araç saglanmis olur.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/030,388 US6287693B1 (en) | 1998-02-25 | 1998-02-25 | Stable shaped particles of crystalline organic compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TR200002462T2 true TR200002462T2 (tr) | 2000-11-21 |
Family
ID=21853984
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TR2000/02462T TR200002462T2 (tr) | 1998-02-25 | 1999-02-10 | Kristalimsi organik bileşiklerin dengeli şekilli parçacıkları |
Country Status (34)
| Country | Link |
|---|---|
| US (7) | US6287693B1 (tr) |
| EP (4) | EP2085075B1 (tr) |
| JP (2) | JP4885357B2 (tr) |
| KR (1) | KR100726315B1 (tr) |
| CN (2) | CN1146407C (tr) |
| AR (3) | AR018107A1 (tr) |
| AT (2) | ATE345779T1 (tr) |
| AU (1) | AU747779B2 (tr) |
| BR (1) | BR9908156A (tr) |
| CA (1) | CA2319176C (tr) |
| CL (1) | CL2010001333A1 (tr) |
| CY (1) | CY1118522T1 (tr) |
| CZ (1) | CZ301042B6 (tr) |
| DE (2) | DE69934099T2 (tr) |
| DK (3) | DK1772141T3 (tr) |
| EE (1) | EE05019B1 (tr) |
| ES (3) | ES2275334T3 (tr) |
| HU (1) | HUP0101271A3 (tr) |
| ID (1) | ID26523A (tr) |
| IL (2) | IL137970A0 (tr) |
| MY (1) | MY138375A (tr) |
| NO (1) | NO331804B1 (tr) |
| NZ (1) | NZ505987A (tr) |
| PE (1) | PE20000393A1 (tr) |
| PL (1) | PL196369B1 (tr) |
| PT (1) | PT2085075T (tr) |
| RU (1) | RU2225708C2 (tr) |
| SA (1) | SA99200098B1 (tr) |
| TR (1) | TR200002462T2 (tr) |
| TW (1) | TWI256308B (tr) |
| UA (1) | UA73470C2 (tr) |
| UY (1) | UY25404A1 (tr) |
| WO (1) | WO1999043304A1 (tr) |
| ZA (1) | ZA991058B (tr) |
Families Citing this family (44)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6287693B1 (en) | 1998-02-25 | 2001-09-11 | John Claude Savoir | Stable shaped particles of crystalline organic compounds |
| US6667344B2 (en) | 2001-04-17 | 2003-12-23 | Dey, L.P. | Bronchodilating compositions and methods |
| ES2503551T5 (es) | 2002-05-16 | 2021-10-28 | Janssen Sciences Ireland Unlimited Co | Formas pseudopolimórficas de un inhibidor de la proteasa de VIH |
| US20040028747A1 (en) * | 2002-08-06 | 2004-02-12 | Tucker Christopher J. | Crystalline drug particles prepared using a controlled precipitation process |
| US20040028746A1 (en) * | 2002-08-06 | 2004-02-12 | Sonke Svenson | Crystalline drug particles prepared using a controlled precipitation (recrystallization) process |
| ES2340422T3 (es) * | 2003-06-13 | 2010-06-02 | Skendi Finance, Ltd. | Microparticulas constituidas por estradiol y colesterol. |
| TWI359675B (en) | 2003-07-10 | 2012-03-11 | Dey L P | Bronchodilating β-agonist compositions |
| JP2007508240A (ja) * | 2003-07-22 | 2007-04-05 | バクスター・インターナショナル・インコーポレイテッド | 低分子量有機分子の小球状粒子ならびにその調製方法および使用方法 |
| JP2007513145A (ja) * | 2003-12-04 | 2007-05-24 | ファイザー・プロダクツ・インク | 医薬用多微粒子の製造方法 |
| LT2351555T (lt) * | 2004-02-23 | 2016-12-27 | Euro-Celtique S.A. | Piktnaudžiavimui atspari priemonė, skirta transderminiam opoido įvedimui |
| US20080200682A1 (en) * | 2005-06-17 | 2008-08-21 | Basf Aktiengesellschaft | Process of Producing Bleach Boosters |
| EP2254561A2 (en) * | 2008-03-26 | 2010-12-01 | AllTranz Inc. | Abuse deterrent transdermal formulations of opiate agonists and agonist-antagonists |
| JP2011516606A (ja) * | 2008-04-14 | 2011-05-26 | ポジ ビジョナリー ソリューションズ エルエルピー | 様々な治療指標に必要な血漿プロゲステロン濃度を得るための方法および医薬組成物 |
| FR2939326B1 (fr) * | 2008-12-10 | 2011-04-01 | Univ Joseph Fourier | Procede et dispositif de controle d'une cristallisation. |
| EP2477610A1 (en) | 2009-09-17 | 2012-07-25 | Upsher-Smith Laboratories, Inc. | A sustained-release product comprising a combination of a non-opioid amine and a non-steroidal anti -inflammatory drug |
| UY33103A (es) | 2009-12-15 | 2011-07-29 | Techsphere S A De C V | Formulacion farmaceutica parenteral en suspension, de liberacion sostenida, en dosis baja y ultra baja, en terapia hormonal en el sindrome climaterico |
| CN102791719B (zh) * | 2010-03-19 | 2015-07-29 | 第一三共株式会社 | 二胺衍生物的晶体及其制备方法 |
| US9351924B2 (en) | 2011-03-11 | 2016-05-31 | Snu R&Db Foundation | Drug delivery system including laminated structure |
| KR101314126B1 (ko) | 2011-03-11 | 2013-10-04 | 서울대학교산학협력단 | 다면체 형상의 약물 전달 시스템 |
| RS62297B1 (sr) | 2011-11-23 | 2021-09-30 | Therapeuticsmd Inc | Prirodne kombinovane hormonske supstitucione formulacije i terapije |
| US9301920B2 (en) | 2012-06-18 | 2016-04-05 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
| US20130338122A1 (en) | 2012-06-18 | 2013-12-19 | Therapeuticsmd, Inc. | Transdermal hormone replacement therapies |
| US10806740B2 (en) | 2012-06-18 | 2020-10-20 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
| US20150196640A1 (en) | 2012-06-18 | 2015-07-16 | Therapeuticsmd, Inc. | Progesterone formulations having a desirable pk profile |
| US10806697B2 (en) | 2012-12-21 | 2020-10-20 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US11246875B2 (en) | 2012-12-21 | 2022-02-15 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US11266661B2 (en) | 2012-12-21 | 2022-03-08 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US9180091B2 (en) | 2012-12-21 | 2015-11-10 | Therapeuticsmd, Inc. | Soluble estradiol capsule for vaginal insertion |
| US10568891B2 (en) | 2012-12-21 | 2020-02-25 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US10537581B2 (en) | 2012-12-21 | 2020-01-21 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US10471072B2 (en) | 2012-12-21 | 2019-11-12 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US9227985B2 (en) | 2013-03-15 | 2016-01-05 | Incyte Corporation | Tricyclic heterocycles as bet protein inhibitors |
| US9309246B2 (en) | 2013-12-19 | 2016-04-12 | Incyte Corporation | Tricyclic heterocycles as BET protein inhibitors |
| MY180775A (en) | 2014-04-23 | 2020-12-09 | Incyte Corp | 1h-pyrrolo[2,3-c]pyridin-7(6h)-ones and pyrazolo[3,4-c]pyridin-7(6h)-ones as inhibitors of bet proteins |
| RU2016143081A (ru) | 2014-05-22 | 2018-06-26 | Терапьютиксмд, Инк. | Натуральные комбинированные гормонозаместительные составы и терапии |
| US10328087B2 (en) | 2015-07-23 | 2019-06-25 | Therapeuticsmd, Inc. | Formulations for solubilizing hormones |
| ITUB20153652A1 (it) | 2015-09-16 | 2017-03-16 | Fatro Spa | Microsfere contenenti lattoni macrociclici antielminitici |
| US9931349B2 (en) | 2016-04-01 | 2018-04-03 | Therapeuticsmd, Inc. | Steroid hormone pharmaceutical composition |
| US10286077B2 (en) | 2016-04-01 | 2019-05-14 | Therapeuticsmd, Inc. | Steroid hormone compositions in medium chain oils |
| KR102643344B1 (ko) | 2016-06-20 | 2024-03-07 | 인사이트 코포레이션 | Bet 저해제의 결정질 고체 형태 |
| PL236889B1 (pl) * | 2017-10-03 | 2021-02-22 | Univ Warszawski Medyczny | Nowa forma krystaliczna bezwodnego 17-β-estradiolu, sposób jej otrzymywania oraz kompozycja farmaceutyczna zawierająca nową formę krystaliczną bezwodnego 17-β-estradiolu i jej zastosowanie |
| EP3542786A1 (en) * | 2018-03-21 | 2019-09-25 | ITF Research Pharma, S.L.U. | Progesterone intravaginal devices |
| US11633405B2 (en) | 2020-02-07 | 2023-04-25 | Therapeuticsmd, Inc. | Steroid hormone pharmaceutical formulations |
| US11833155B2 (en) | 2020-06-03 | 2023-12-05 | Incyte Corporation | Combination therapy for treatment of myeloproliferative neoplasms |
Family Cites Families (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2447362A (en) | 1945-11-01 | 1948-08-17 | Rca Corp | Production of crystals |
| US3800038A (en) * | 1972-04-21 | 1974-03-26 | Biolog Concepts Inc | Uterine administraton of eutectic solid solutions of steroid hormones in a steroidal lipid carrier |
| US4230621A (en) * | 1978-05-01 | 1980-10-28 | E. R. Squibb & Sons, Inc. | Steroid derivatives and their use in radioimmunoassays |
| DE2843963A1 (de) * | 1978-10-09 | 1980-04-24 | Merck Patent Gmbh | Im koerper resorbierbare geformte masse auf basis von kollagen und ihre verwendung in der medizin |
| IL63968A (en) | 1980-10-01 | 1985-10-31 | Glaxo Group Ltd | Form 2 ranitidine hydrochloride,its preparation and pharmaceutical compositions containing it |
| JPS5799562A (en) | 1980-12-12 | 1982-06-21 | Nippon Shinyaku Co Ltd | Preparation of microcrystal |
| DE3049196A1 (de) | 1980-12-24 | 1982-07-29 | Bayer Ag, 5090 Leverkusen | Verfahren zur herstellung von granulaten aus organischen in form einer schmelze vorliegenden stoffen |
| US4447426A (en) * | 1982-01-18 | 1984-05-08 | E. R. Squibb & Sons, Inc. | Steroid monohydrates, formulations containing same and method |
| JPS58143832A (ja) | 1982-02-22 | 1983-08-26 | Yoshiaki Kawashima | 結晶性化学物質の球状化再結晶法 |
| DE3213025C2 (de) | 1982-04-02 | 1997-06-12 | Fischer Karl Ind Gmbh | Verfahren zur Nachkondensation von Polykondensaten |
| GB8618847D0 (en) * | 1986-08-01 | 1986-09-10 | Smith Kline French Lab | Pharmaceutical formulations |
| JPH0714625B2 (ja) | 1987-03-30 | 1995-02-22 | 呉羽化学工業株式会社 | 高結晶化ポリアリ−レンチオエ−テル成形物 |
| US4897307A (en) | 1987-08-11 | 1990-01-30 | The Dow Chemical Company | Process for the solvent-induced crystallization of amorphous poly(etheretherketone)-type polymers and the article formed thereby |
| EP0338085B1 (en) | 1987-09-28 | 1994-06-22 | Asahi Kasei Kogyo Kabushiki Kaisha | Process for preparing crystallized aromatic polycarbonate and crystallized aromatic polycarbonate obtained by the process |
| US4919899A (en) | 1988-02-29 | 1990-04-24 | Herrmann Frederick T | Crystal growth apparatus |
| YU120988A (en) * | 1988-06-23 | 1990-06-30 | Lek Tovarna Farmacevtskih | Process for preparing new dispersion pills of cimetidine |
| IT1230566B (it) * | 1988-10-17 | 1991-10-28 | Vectorpharma Int | Farmaci poco solubili supportati su sostanze polimeriche in forma atta all'aumento della velocita' di dissoluzione |
| US5360478A (en) | 1989-10-16 | 1994-11-01 | Phasex Corporation | Gas anti-solvent recrystallization process |
| FR2663224B1 (fr) * | 1990-06-14 | 1995-01-20 | Applicationes Farmaceuticas Sa | Forme galenique parenterale. |
| FR2663223B1 (fr) | 1990-06-14 | 1994-12-02 | Af Aplicaciones Far Lab | Forme galenique parenterale. |
| JPH04305226A (ja) | 1991-01-25 | 1992-10-28 | Senichi Masuda | ガス中窒素酸化物の低減方法 |
| US5145684A (en) * | 1991-01-25 | 1992-09-08 | Sterling Drug Inc. | Surface modified drug nanoparticles |
| SE9101090D0 (sv) * | 1991-04-11 | 1991-04-11 | Astra Ab | Process for conditioning of water-soluble substances |
| SE9302777D0 (sv) * | 1993-08-27 | 1993-08-27 | Astra Ab | Process for conditioning substances |
| US5874063A (en) * | 1991-04-11 | 1999-02-23 | Astra Aktiebolag | Pharmaceutical formulation |
| US5391810A (en) | 1991-05-23 | 1995-02-21 | Ajinomoto Co., Inc. | Method of crystallizing α-L-aspartyl-L-phenylalanine methyl ester |
| DE4130173A1 (de) | 1991-09-11 | 1993-03-18 | Bayer Ag | Pharmazeutische zubereitungen mit einer speziellen kristallmodifikation des 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridindicarbonsaeure-isopropyl-(2-methoxyethyl)-esters |
| DE4218929C1 (tr) | 1992-06-10 | 1993-09-09 | Deutsche Bundesbahn, Vertreten Durch Das Bundesbahn-Zentralamt Minden (Westf.), 4950 Minden, De | |
| US5290913A (en) | 1992-10-08 | 1994-03-01 | Carrier Vibrating Equipment, Inc. | Method and apparatus for the heat treatment of material |
| US5558678A (en) | 1992-11-13 | 1996-09-24 | Karl Fischer Industrieanlagen Gmbh | Process and apparatus for continuous crystallization of plastic granules |
| US5643595A (en) | 1992-11-24 | 1997-07-01 | Alkermes Controlled Therapeutics Inc. Ii | Growth promoters for animals |
| WO1994020116A1 (en) * | 1993-03-10 | 1994-09-15 | University Of Alabama Research Foundation | Artificial primers for glycogen synthesis |
| US5409605A (en) * | 1993-08-05 | 1995-04-25 | Chemical Lime Company | Apparatus and method for treating waste sludge |
| JPH0757558A (ja) * | 1993-08-09 | 1995-03-03 | Showa Electric Wire & Cable Co Ltd | 耐熱絶縁電線 |
| DE4440337A1 (de) * | 1994-11-11 | 1996-05-15 | Dds Drug Delivery Services Ges | Pharmazeutische Nanosuspensionen zur Arzneistoffapplikation als Systeme mit erhöhter Sättigungslöslichkeit und Lösungsgeschwindigkeit |
| US5849651A (en) * | 1995-06-01 | 1998-12-15 | Kabushiki Kaisha Toshiba | Reversible thermal recording medium |
| JPH0957558A (ja) * | 1995-08-18 | 1997-03-04 | Nabeya Iron & Tool Works Ltd | スライド装置 |
| JPH09227558A (ja) * | 1996-02-28 | 1997-09-02 | Fujisawa Pharmaceut Co Ltd | チアゾール化合物の安定な結晶およびその製造方法 |
| US6287693B1 (en) | 1998-02-25 | 2001-09-11 | John Claude Savoir | Stable shaped particles of crystalline organic compounds |
| JP2000143832A (ja) | 1998-11-10 | 2000-05-26 | Toppan Printing Co Ltd | 高剛性を有するフィルムまたはシート |
-
1998
- 1998-02-25 US US09/030,388 patent/US6287693B1/en not_active Expired - Lifetime
-
1999
- 1999-02-10 ZA ZA9901058A patent/ZA991058B/xx unknown
- 1999-02-10 CZ CZ20003047A patent/CZ301042B6/cs not_active IP Right Cessation
- 1999-02-10 DE DE69934099T patent/DE69934099T2/de not_active Expired - Lifetime
- 1999-02-10 ES ES99902729T patent/ES2275334T3/es not_active Expired - Lifetime
- 1999-02-10 KR KR1020007009352A patent/KR100726315B1/ko not_active Expired - Fee Related
- 1999-02-10 PT PT91562686T patent/PT2085075T/pt unknown
- 1999-02-10 WO PCT/IB1999/000233 patent/WO1999043304A1/en not_active Ceased
- 1999-02-10 NZ NZ505987A patent/NZ505987A/en not_active IP Right Cessation
- 1999-02-10 DK DK06022834T patent/DK1772141T3/da active
- 1999-02-10 EP EP09156268.6A patent/EP2085075B1/en not_active Expired - Lifetime
- 1999-02-10 AU AU22936/99A patent/AU747779B2/en not_active Expired
- 1999-02-10 CN CNB998032794A patent/CN1146407C/zh not_active Expired - Fee Related
- 1999-02-10 AT AT99902729T patent/ATE345779T1/de active
- 1999-02-10 CN CNB2004100076469A patent/CN100528140C/zh not_active Expired - Fee Related
- 1999-02-10 TR TR2000/02462T patent/TR200002462T2/tr unknown
- 1999-02-10 DK DK99902729T patent/DK1056444T3/da active
- 1999-02-10 PL PL343170A patent/PL196369B1/pl unknown
- 1999-02-10 ES ES06022834T patent/ES2324366T3/es not_active Expired - Lifetime
- 1999-02-10 EP EP10183811A patent/EP2319497B1/en not_active Expired - Lifetime
- 1999-02-10 HU HU0101271A patent/HUP0101271A3/hu unknown
- 1999-02-10 EP EP06022834A patent/EP1772141B1/en not_active Expired - Lifetime
- 1999-02-10 AT AT06022834T patent/ATE427102T1/de active
- 1999-02-10 DE DE69940684T patent/DE69940684D1/de not_active Expired - Lifetime
- 1999-02-10 RU RU2000124327/15A patent/RU2225708C2/ru not_active IP Right Cessation
- 1999-02-10 CA CA002319176A patent/CA2319176C/en not_active Expired - Fee Related
- 1999-02-10 ID IDW20001723A patent/ID26523A/id unknown
- 1999-02-10 ES ES09156268.6T patent/ES2609284T3/es not_active Expired - Lifetime
- 1999-02-10 BR BR9908156-3A patent/BR9908156A/pt not_active Application Discontinuation
- 1999-02-10 EP EP99902729A patent/EP1056444B1/en not_active Expired - Lifetime
- 1999-02-10 JP JP2000533103A patent/JP4885357B2/ja not_active Expired - Fee Related
- 1999-02-10 EE EEP200000492A patent/EE05019B1/xx unknown
- 1999-02-10 DK DK09156268.6T patent/DK2085075T3/en active
- 1999-02-10 IL IL13797099A patent/IL137970A0/xx active IP Right Grant
- 1999-02-12 MY MYPI99000491A patent/MY138375A/en unknown
- 1999-02-17 PE PE1999000141A patent/PE20000393A1/es not_active IP Right Cessation
- 1999-02-23 AR ARP990100728A patent/AR018107A1/es not_active Application Discontinuation
- 1999-02-24 UY UY25404A patent/UY25404A1/es not_active Application Discontinuation
- 1999-03-12 TW TW088103853A patent/TWI256308B/zh not_active IP Right Cessation
- 1999-05-05 SA SA99200098A patent/SA99200098B1/ar unknown
- 1999-10-02 UA UA2000095446A patent/UA73470C2/uk unknown
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2000
- 2000-07-12 US US09/615,061 patent/US6537580B1/en not_active Expired - Lifetime
- 2000-08-20 IL IL137970A patent/IL137970A/en not_active IP Right Cessation
- 2000-08-24 NO NO20004241A patent/NO331804B1/no not_active IP Right Cessation
-
2001
- 2001-05-23 US US09/862,723 patent/US6528094B1/en not_active Expired - Lifetime
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2002
- 2002-01-15 US US10/045,148 patent/US6638536B2/en not_active Expired - Lifetime
- 2002-05-29 US US10/156,079 patent/US6663895B2/en not_active Expired - Lifetime
-
2003
- 2003-02-26 US US10/373,088 patent/US6737081B2/en not_active Expired - Lifetime
- 2003-02-26 US US10/372,897 patent/US7427413B2/en not_active Expired - Fee Related
-
2010
- 2010-03-17 AR ARP100100844A patent/AR077167A2/es not_active Application Discontinuation
- 2010-03-17 AR ARP100100845A patent/AR077168A2/es not_active Application Discontinuation
- 2010-12-02 CL CL2010001333A patent/CL2010001333A1/es unknown
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2011
- 2011-07-22 JP JP2011161017A patent/JP2011241220A/ja not_active Withdrawn
-
2016
- 2016-12-28 CY CY20161101356T patent/CY1118522T1/el unknown
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