TR200401007T4 - Azabisiklik karbamatlar ve bunların, alfa-7 nikotinik asetilkolin reseptör agonistleri olarak kullanımları - Google Patents

Azabisiklik karbamatlar ve bunların, alfa-7 nikotinik asetilkolin reseptör agonistleri olarak kullanımları

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Publication number
TR200401007T4
TR200401007T4 TR2004/01007T TR200401007T TR200401007T4 TR 200401007 T4 TR200401007 T4 TR 200401007T4 TR 2004/01007 T TR2004/01007 T TR 2004/01007T TR 200401007 T TR200401007 T TR 200401007T TR 200401007 T4 TR200401007 T4 TR 200401007T4
Authority
TR
Turkey
Prior art keywords
alpha
formula
carbamates
receptor agonists
acetylcholine receptor
Prior art date
Application number
TR2004/01007T
Other languages
English (en)
Inventor
Nozulak Joachim
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of TR200401007T4 publication Critical patent/TR200401007T4/tr

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Neurology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Psychology (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Bulus; yeni azabisiklik karbamatlar, bunlarin hazirlanmalari, farmasötikler olarak kullanimlari ve bahsedilen azabisiklik karbamatlari içeren farmasötik kompozisyonlar ile ilgilidir. özellikle, bulus psikotik ve nörodejeneratif rahatsizliklarin tedavisinde kullanim için, serbest baz veya asit eklenik tuz formundaki formül(1) deki bir bilesigi saglamakta olup, formül (I) içerisindeki n, 1 veya 2' dir, R1 R2 ve R3; bagimsiz olarak, hidrojen veya (C1-4) alkildir ve A, asagida formül (I)' in altinda belirtilmis formüllerdeki bir grup olup, söz konusu formüller içerisindeki m; 1, 2 veya 3' tür, X; O, S, NH veya CH2' dir ve R4 ve R5; bagimsiz olarak, hidrojen, halojen, hidroksi, (C1-4) alkil, (C1-4) alkoksi, (C1-4) alkiltiyo, (C1-4) alkilamino, nitro, triflorometil veya fenildir.
TR2004/01007T 2000-05-05 2001-05-03 Azabisiklik karbamatlar ve bunların, alfa-7 nikotinik asetilkolin reseptör agonistleri olarak kullanımları TR200401007T4 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0010955.3A GB0010955D0 (en) 2000-05-05 2000-05-05 Organic compounds

Publications (1)

Publication Number Publication Date
TR200401007T4 true TR200401007T4 (tr) 2004-07-21

Family

ID=9891092

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2004/01007T TR200401007T4 (tr) 2000-05-05 2001-05-03 Azabisiklik karbamatlar ve bunların, alfa-7 nikotinik asetilkolin reseptör agonistleri olarak kullanımları

Country Status (29)

Country Link
US (1) US6780861B2 (tr)
EP (1) EP1282620B1 (tr)
JP (1) JP4898062B2 (tr)
KR (1) KR20020093974A (tr)
CN (1) CN1167703C (tr)
AR (1) AR028073A1 (tr)
AT (1) ATE263167T1 (tr)
AU (2) AU2001262257B2 (tr)
BR (1) BR0110521A (tr)
CA (1) CA2407972C (tr)
CZ (1) CZ20023622A3 (tr)
DE (1) DE60102581T2 (tr)
DK (1) DK1282620T3 (tr)
ES (1) ES2218418T3 (tr)
GB (1) GB0010955D0 (tr)
HK (1) HK1054223B (tr)
HU (1) HUP0301866A2 (tr)
IL (1) IL152417A0 (tr)
MX (1) MXPA02010892A (tr)
NO (1) NO20025280D0 (tr)
NZ (1) NZ522226A (tr)
PE (1) PE20020221A1 (tr)
PL (1) PL357435A1 (tr)
PT (1) PT1282620E (tr)
RU (1) RU2002131886A (tr)
SK (1) SK15612002A3 (tr)
TR (1) TR200401007T4 (tr)
WO (1) WO2001085727A1 (tr)
ZA (1) ZA200208969B (tr)

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Also Published As

Publication number Publication date
WO2001085727A1 (en) 2001-11-15
AU6225701A (en) 2001-11-20
NO20025280L (no) 2002-11-04
PE20020221A1 (es) 2002-04-23
CZ20023622A3 (cs) 2003-02-12
ZA200208969B (en) 2003-10-07
PT1282620E (pt) 2004-07-30
CN1167703C (zh) 2004-09-22
US20030166654A1 (en) 2003-09-04
HUP0301866A2 (hu) 2003-09-29
NO20025280D0 (no) 2002-11-04
GB0010955D0 (en) 2000-06-28
BR0110521A (pt) 2003-04-08
US6780861B2 (en) 2004-08-24
ES2218418T3 (es) 2004-11-16
KR20020093974A (ko) 2002-12-16
EP1282620B1 (en) 2004-03-31
EP1282620A1 (en) 2003-02-12
DK1282620T3 (da) 2004-07-19
HK1054223A1 (en) 2003-11-21
RU2002131886A (ru) 2004-04-10
CN1427840A (zh) 2003-07-02
DE60102581T2 (de) 2005-02-03
HK1054223B (en) 2005-03-04
ATE263167T1 (de) 2004-04-15
JP2003532731A (ja) 2003-11-05
IL152417A0 (en) 2003-05-29
SK15612002A3 (sk) 2003-04-01
CA2407972C (en) 2010-03-09
JP4898062B2 (ja) 2012-03-14
AU2001262257B2 (en) 2004-11-04
PL357435A1 (en) 2004-07-26
DE60102581D1 (de) 2004-05-06
MXPA02010892A (es) 2003-03-27
NZ522226A (en) 2004-08-27
AR028073A1 (es) 2003-04-23
CA2407972A1 (en) 2001-11-15

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