UA76936C2 - Human monoclonal antibody binding the antigen-4 of cytotoxic t-lymphocyte (ctla-4), nucleic acid, cell line, method of obtaining transgenic mammal, method to increase producing il-2 or ifn-? in the t-cells of a patient, method to treat and pharmaceutical composition used in treatment of cancer, inflammation or autoimmune disease, including the antibody - Google Patents

Human monoclonal antibody binding the antigen-4 of cytotoxic t-lymphocyte (ctla-4), nucleic acid, cell line, method of obtaining transgenic mammal, method to increase producing il-2 or ifn-? in the t-cells of a patient, method to treat and pharmaceutical composition used in treatment of cancer, inflammation or autoimmune disease, including the antibody Download PDF

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Publication number
UA76936C2
UA76936C2 UA2001075213A UA2001075213A UA76936C2 UA 76936 C2 UA76936 C2 UA 76936C2 UA 2001075213 A UA2001075213 A UA 2001075213A UA 2001075213 A UA2001075213 A UA 2001075213A UA 76936 C2 UA76936 C2 UA 76936C2
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Ukraine
Prior art keywords
antibody
amino acid
acid sequence
sequence
sti
Prior art date
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UA2001075213A
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English (en)
Ukrainian (uk)
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Pfizer
Abgenix Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication of UA76936C2 publication Critical patent/UA76936C2/uk

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2818—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD28 or CD152
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man

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  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
UA2001075213A 1998-12-23 1999-12-23 Human monoclonal antibody binding the antigen-4 of cytotoxic t-lymphocyte (ctla-4), nucleic acid, cell line, method of obtaining transgenic mammal, method to increase producing il-2 or ifn-? in the t-cells of a patient, method to treat and pharmaceutical composition used in treatment of cancer, inflammation or autoimmune disease, including the antibody UA76936C2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11364798P 1998-12-23 1998-12-23
PCT/US1999/030895 WO2000037504A2 (fr) 1998-12-23 1999-12-23 Anticorps monoclonaux humains diriges contre l'antigene ctla-4

Publications (1)

Publication Number Publication Date
UA76936C2 true UA76936C2 (en) 2006-10-16

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
UA2001075213A UA76936C2 (en) 1998-12-23 1999-12-23 Human monoclonal antibody binding the antigen-4 of cytotoxic t-lymphocyte (ctla-4), nucleic acid, cell line, method of obtaining transgenic mammal, method to increase producing il-2 or ifn-? in the t-cells of a patient, method to treat and pharmaceutical composition used in treatment of cancer, inflammation or autoimmune disease, including the antibody

Country Status (41)

Country Link
EP (3) EP2112166B1 (fr)
JP (2) JP3793693B2 (fr)
KR (3) KR100849443B1 (fr)
CN (1) CN1328571B (fr)
AP (1) AP1590A (fr)
AT (1) ATE458008T1 (fr)
AU (1) AU772676B2 (fr)
BG (1) BG65899B1 (fr)
BR (2) BRPI9916853B8 (fr)
CA (1) CA2356215C (fr)
CR (2) CR6425A (fr)
CU (1) CU23292B7 (fr)
CY (1) CY1121451T1 (fr)
CZ (2) CZ303703B6 (fr)
DE (1) DE69942037D1 (fr)
DK (2) DK1141028T3 (fr)
EA (1) EA006972B1 (fr)
EE (1) EE05483B1 (fr)
ES (2) ES2706547T3 (fr)
GE (1) GEP20053594B (fr)
HK (1) HK1041274B (fr)
HR (2) HRP20010551B1 (fr)
HU (2) HU229566B1 (fr)
ID (1) ID29991A (fr)
IL (2) IL143797A0 (fr)
IS (2) IS2798B (fr)
LT (1) LT2112166T (fr)
MX (1) MXPA01006422A (fr)
NO (2) NO332618B1 (fr)
NZ (1) NZ512553A (fr)
OA (1) OA11917A (fr)
PL (2) PL214003B1 (fr)
PT (2) PT1141028E (fr)
RS (1) RS51309B (fr)
SG (2) SG143018A1 (fr)
SI (2) SI1141028T1 (fr)
SK (2) SK288057B6 (fr)
TR (2) TR200200735T2 (fr)
UA (1) UA76936C2 (fr)
WO (1) WO2000037504A2 (fr)
ZA (1) ZA200105742B (fr)

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