UA77950C2 - Use of mutants of cc chemokines for treatment of multiple sclerosis - Google Patents

Use of mutants of cc chemokines for treatment of multiple sclerosis Download PDF

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Publication number: UA77950C2
Authority: UA; Ukraine
Prior art keywords: mutant; chemokine; amino acids; mir; kamte5
Prior art date: 2000-10-04

Application number

UA2003044038A

Other languages

English (en)

Ukrainian (uk)

Original Assignee

Applied Research Systems

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-10-04

Filing date

2001-03-10

Publication date

2007-02-15

2001-03-10 Application filed by Applied Research Systems filed Critical Applied Research Systems

2007-02-15 Publication of UA77950C2 publication Critical patent/UA77950C2/uk

Links

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Classifications

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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/521—Chemokines
- C07K14/523—Beta-chemokines, e.g. RANTES, I-309/TCA-3, MIP-1alpha, MIP-1beta/ACT-2/LD78/SCIF, MCP-1/MCAF, MCP-2, MCP-3, LDCF-1, LDCF-2
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Zoology (AREA)
Biomedical Technology (AREA)
Gastroenterology & Hepatology (AREA)
Pharmacology & Pharmacy (AREA)
Neurosurgery (AREA)
Animal Behavior & Ethology (AREA)
Neurology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Molecular Biology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Toxicology (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Genetics & Genomics (AREA)
Immunology (AREA)
Hospice & Palliative Care (AREA)
Psychiatry (AREA)
Epidemiology (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Enzymes And Modification Thereof (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

UA2003044038A 2000-10-04 2001-03-10 Use of mutants of cc chemokines for treatment of multiple sclerosis UA77950C2 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP00121665		2000-10-04
PCT/EP2001/011428 WO2002028419A2 (en)	2000-10-04	2001-10-03	Chemokine mutants in the treatment of multiple sclerosis

Publications (1)

Publication Number	Publication Date
UA77950C2 true UA77950C2 (en)	2007-02-15

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ID=8170011

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
UA2003044038A UA77950C2 (en)	2000-10-04	2001-03-10	Use of mutants of cc chemokines for treatment of multiple sclerosis

Country Status (30)

Country	Link
US (1)	US7402303B2 (sr)
EP (1)	EP1326628B1 (sr)
JP (1)	JP3908165B2 (sr)
KR (1)	KR100837898B1 (sr)
CN (1)	CN1285381C (sr)
AR (1)	AR030854A1 (sr)
AT (1)	ATE265222T1 (sr)
AU (2)	AU2002215919B2 (sr)
BG (1)	BG66137B1 (sr)
BR (1)	BR0114407A (sr)
CA (1)	CA2423616C (sr)
CZ (1)	CZ303409B6 (sr)
DE (1)	DE60103078T2 (sr)
DK (1)	DK1326628T3 (sr)
EA (1)	EA006137B1 (sr)
EE (1)	EE05174B1 (sr)
ES (1)	ES2217199T3 (sr)
HR (1)	HRP20030215B1 (sr)
HU (1)	HUP0302194A3 (sr)
IL (2)	IL155178A0 (sr)
MX (1)	MXPA03003008A (sr)
NO (1)	NO330278B1 (sr)
PL (1)	PL204231B1 (sr)
PT (1)	PT1326628E (sr)
RS (1)	RS50738B (sr)
SI (1)	SI1326628T1 (sr)
SK (1)	SK287523B6 (sr)
UA (1)	UA77950C2 (sr)
WO (1)	WO2002028419A2 (sr)
ZA (1)	ZA200302315B (sr)

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Publication number	Priority date	Publication date	Assignee	Title
EP1458756B1 (en)	2001-12-17	2009-01-28	Laboratoires Serono SA	Chemokine mutants acting as chemokine antagonists
US7335350B2 (en)	2002-04-04	2008-02-26	Laboratoires Serono Sa	Chemokines mutants having improved oral bioavailability
ATE394117T1 (de)	2002-12-23	2008-05-15	Serono Lab	Verwendung von cc-chemokine ccl5/rantes mutanten zur behandlung von lebererkrankungen
JP2007533300A (ja) *	2003-10-22	2007-11-22	アプライドリサーチシステムズエーアールエスホールディングナームロゼフェンノートシャップ	新規のｃｘｃｌ８アンタゴニスト
AT412785B (de) *	2003-12-04	2005-07-25	Kungl Andreas J Dr	Gag-bindungsproteine
DK1439191T3 (da) *	2004-01-19	2006-08-14	Ares Trading Sa	Proces til oprensning af bakterielt udtrykte proteiner
GB0412400D0 (en) *	2004-06-03	2004-07-07	Univ Newcastle	Treatment of inflammatory conditions
EP2218748B1 (en) *	2005-09-03	2012-10-10	Samsung SDI Co., Ltd.	Polybenzoxazine-based compound, electrolyte membrane including the same, and fuel cell employing the electrolyte membrane
GB0614755D0 (en)	2006-07-25	2006-09-06	Univ Geneve	Cytokine derivatives
ES2453592T3 (es)	2007-08-02	2014-04-08	Novimmune Sa	Anticuerpos anti-RANTES y métodos de uso de los mismos
EP2539354B1 (en) *	2010-02-08	2017-04-05	The Trustees Of The University Of Pennsylvania	Nucleic acid molecules encoding rantes, and compositions comprising and methods of using the same
WO2019229615A1 (en)	2018-05-28	2019-12-05	Université De Genève	Methods of inhibiting cerebral inflammation
US20250186520A1 (en) *	2020-10-26	2025-06-12	City Of Hope	Oncolytic virus compositions and methods for the treatment of cancer

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5739103A (en) *	1993-11-12	1998-04-14	Dana-Farber Cancer Institute	Chemokine N-terminal deletion mutations
WO1998006751A1 (en) *	1996-08-16	1998-02-19	Research Corporation Technologies, Inc.	Mcp-3, rantes and mip-1alpha receptor antagonists
EP0906954A1 (en) *	1997-09-29	1999-04-07	Applied Research Systems ARS Holding N.V.	Amino-terminal truncated c-c chemokines as chemokine antagonist
ATE308617T1 (de)	1997-12-23	2005-11-15	San Raffaele Centro Fond	Rantes mutanten und deren therapeutischen anwendungen
AU2740900A (en) *	1999-01-29	2000-08-18	Millennium Pharmaceuticals, Inc.	Method of treating demyelinating inflammatory disease using ccr1 antagonists

2001
- 2001-03-10 UA UA2003044038A patent/UA77950C2/uk unknown
- 2001-10-03 US US10/398,457 patent/US7402303B2/en not_active Expired - Fee Related
- 2001-10-03 AU AU2002215919A patent/AU2002215919B2/en not_active Ceased
- 2001-10-03 EP EP01986265A patent/EP1326628B1/en not_active Expired - Lifetime
- 2001-10-03 HR HR20030215A patent/HRP20030215B1/xx not_active IP Right Cessation
- 2001-10-03 PL PL362350A patent/PL204231B1/pl not_active IP Right Cessation
- 2001-10-03 WO PCT/EP2001/011428 patent/WO2002028419A2/en not_active Ceased
- 2001-10-03 SI SI200130130T patent/SI1326628T1/xx unknown
- 2001-10-03 EE EEP200300139A patent/EE05174B1/xx not_active IP Right Cessation
- 2001-10-03 IL IL15517801A patent/IL155178A0/xx unknown
- 2001-10-03 HU HU0302194A patent/HUP0302194A3/hu unknown
- 2001-10-03 BR BR0114407-3A patent/BR0114407A/pt not_active IP Right Cessation
- 2001-10-03 CN CNB018199178A patent/CN1285381C/zh not_active Expired - Fee Related
- 2001-10-03 ES ES01986265T patent/ES2217199T3/es not_active Expired - Lifetime
- 2001-10-03 RS YUP-257/03A patent/RS50738B/sr unknown
- 2001-10-03 CA CA2423616A patent/CA2423616C/en not_active Expired - Fee Related
- 2001-10-03 PT PT01986265T patent/PT1326628E/pt unknown
- 2001-10-03 AU AU1591902A patent/AU1591902A/xx active Pending
- 2001-10-03 DK DK01986265T patent/DK1326628T3/da active
- 2001-10-03 DE DE60103078T patent/DE60103078T2/de not_active Expired - Lifetime
- 2001-10-03 JP JP2002532243A patent/JP3908165B2/ja not_active Expired - Fee Related
- 2001-10-03 MX MXPA03003008A patent/MXPA03003008A/es active IP Right Grant
- 2001-10-03 ZA ZA200302315A patent/ZA200302315B/en unknown
- 2001-10-03 SK SK406-2003A patent/SK287523B6/sk not_active IP Right Cessation
- 2001-10-03 CZ CZ20030947A patent/CZ303409B6/cs not_active IP Right Cessation
- 2001-10-03 AT AT01986265T patent/ATE265222T1/de active
- 2001-10-03 EA EA200300439A patent/EA006137B1/ru not_active IP Right Cessation
- 2001-10-03 KR KR1020037004599A patent/KR100837898B1/ko not_active Expired - Fee Related
- 2001-10-04 AR ARP010104684A patent/AR030854A1/es unknown
2003
- 2003-03-28 BG BG107685A patent/BG66137B1/bg unknown
- 2003-04-01 IL IL155178A patent/IL155178A/en not_active IP Right Cessation
- 2003-04-03 NO NO20031525A patent/NO330278B1/no not_active IP Right Cessation

Also Published As

Publication number	Publication date
CA2423616C (en)	2010-03-16
BR0114407A (pt)	2003-07-29
SI1326628T1 (en)	2004-10-31
KR100837898B1 (ko)	2008-06-13
KR20030034238A (ko)	2003-05-01
DE60103078D1 (de)	2004-06-03
IL155178A (en)	2009-07-20
DK1326628T3 (da)	2004-08-09
AU2002215919B2 (en)	2005-11-24
SK4062003A3 (en)	2003-08-05
US7402303B2 (en)	2008-07-22
HUP0302194A3 (en)	2005-12-28
HK1062811A1 (en)	2004-11-26
MXPA03003008A (es)	2003-07-14
EA200300439A1 (ru)	2003-08-28
AU1591902A (en)	2002-04-15
CZ2003947A3 (cs)	2003-11-12
DE60103078T2 (de)	2005-04-07
ATE265222T1 (de)	2004-05-15
YU25703A (sh)	2006-05-25
HRP20030215A2 (en)	2005-02-28
ES2217199T3 (es)	2004-11-01
HRP20030215B1 (en)	2011-09-30
AR030854A1 (es)	2003-09-03
US20040101509A1 (en)	2004-05-27
HUP0302194A2 (hu)	2003-10-28
PL204231B1 (pl)	2009-12-31
NO20031525D0 (no)	2003-04-03
WO2002028419A2 (en)	2002-04-11
ZA200302315B (en)	2004-03-25
NO20031525L (no)	2003-04-03
JP3908165B2 (ja)	2007-04-25
WO2002028419A3 (en)	2002-06-13
IL155178A0 (en)	2003-11-23
SK287523B6 (sk)	2011-01-04
PT1326628E (pt)	2004-09-30
CN1285381C (zh)	2006-11-22
EP1326628B1 (en)	2004-04-28
NO330278B1 (no)	2011-03-21
EE05174B1 (et)	2009-06-15
CA2423616A1 (en)	2002-04-11
CN1477969A (zh)	2004-02-25
BG66137B1 (bg)	2011-07-29
EE200300139A (et)	2003-06-16
PL362350A1 (en)	2004-10-18
JP2004510426A (ja)	2004-04-08
EA006137B1 (ru)	2005-10-27
EP1326628A2 (en)	2003-07-16
RS50738B (sr)	2010-08-31
CZ303409B6 (cs)	2012-09-05
BG107685A (bg)	2003-11-28

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