YU46128B - Postupak za dobivanje fenil supstituisanih pirido (1,4) benzodiazepina - Google Patents

Postupak za dobivanje fenil supstituisanih pirido (1,4) benzodiazepina

Info

Publication number: YU46128B
Authority: YU; Yugoslavia
Prior art keywords: phenyl; arylmethanone; formula; group; preparation
Prior art date: 1981-09-24

Application number

YU62582A

Other languages

English (en)

Serbo-Croatian (sh)

Other versions

YU62582A (en

Inventor

C.R.J. Taylor

Original Assignee

A.H. Robins Company Inc.

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1981-09-24

Filing date

1982-03-23

Publication date

1993-05-28

1982-03-23 Application filed by A.H. Robins Company Inc. filed Critical A.H. Robins Company Inc.

1986-04-30 Publication of YU62582A publication Critical patent/YU62582A/xx

1993-05-28 Publication of YU46128B publication Critical patent/YU46128B/sh

Links

-1 PHENYL-SUBSTITUTED PYRIDO (1,4) BENZODIAZEPINE Chemical class 0.000 title abstract 4
238000000034 method Methods 0.000 title abstract 2
238000002360 preparation method Methods 0.000 title abstract 2
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 4
125000003545 alkoxy group Chemical group 0.000 abstract 3
125000000217 alkyl group Chemical group 0.000 abstract 3
CJHKJXZMFZKGHI-UHFFFAOYSA-N 1h-pyrido[2,3-i][1,2]benzodiazepine Chemical compound N1N=CC=CC2=CC=C(N=CC=C3)C3=C12 CJHKJXZMFZKGHI-UHFFFAOYSA-N 0.000 abstract 2
229910052739 hydrogen Inorganic materials 0.000 abstract 2
239000001257 hydrogen Substances 0.000 abstract 2
125000004356 hydroxy functional group Chemical group O* 0.000 abstract 2
125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 2
238000007363 ring formation reaction Methods 0.000 abstract 2
125000000175 2-thienyl group Chemical group S1C([*])=C([H])C([H])=C1[H] 0.000 abstract 1
125000001541 3-thienyl group Chemical group S1C([H])=C([*])C([H])=C1[H] 0.000 abstract 1
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
230000001419 dependent effect Effects 0.000 abstract 1
229910052736 halogen Inorganic materials 0.000 abstract 1
125000001475 halogen functional group Chemical group 0.000 abstract 1
150000002367 halogens Chemical class 0.000 abstract 1
238000010438 heat treatment Methods 0.000 abstract 1
150000002431 hydrogen Chemical class 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1
239000002904 solvent Substances 0.000 abstract 1
239000007858 starting material Substances 0.000 abstract 1
125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
- C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Neurosurgery (AREA)
Life Sciences & Earth Sciences (AREA)
Neurology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Psychiatry (AREA)
Pharmacology & Pharmacy (AREA)
Biomedical Technology (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pain & Pain Management (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Pyridine Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

YU62582A 1981-09-24 1982-03-23 Postupak za dobivanje fenil supstituisanih pirido (1,4) benzodiazepina YU46128B (sh)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US30508081A	1981-09-24	1981-09-24

Publications (2)

Publication Number	Publication Date
YU62582A YU62582A (en)	1986-04-30
YU46128B true YU46128B (sh)	1993-05-28

Family

ID=23179241

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
YU62582A YU46128B (sh)	1981-09-24	1982-03-23	Postupak za dobivanje fenil supstituisanih pirido (1,4) benzodiazepina

Country Status (27)

Country	Link
JP (1)	JPS5865290A (da)
KR (1)	KR890000764B1 (da)
BE (1)	BE891666A (da)
CA (1)	CA1199324A (da)
CH (1)	CH651833A5 (da)
DE (1)	DE3150522A1 (da)
DK (3)	DK186282A (da)
EG (1)	EG15904A (da)
ES (6)	ES8303348A1 (da)
FI (1)	FI71935C (da)
FR (1)	FR2515183B1 (da)
GR (1)	GR78473B (da)
HU (2)	HU187393B (da)
IE (1)	IE52493B1 (da)
IL (1)	IL64284A (da)
IN (1)	IN156080B (da)
IT (1)	IT1146728B (da)
LU (1)	LU83865A1 (da)
NL (1)	NL8200549A (da)
NO (1)	NO157700C (da)
NZ (1)	NZ198999A (da)
PH (2)	PH17847A (da)
PL (6)	PL143596B1 (da)
PT (1)	PT74286B (da)
SE (2)	SE448629B (da)
YU (1)	YU46128B (da)
ZA (1)	ZA817866B (da)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3825549A (en) *	1972-10-24	1974-07-23	Squibb & Sons Inc	Certain dihydropyrido(2,1-b)(1,3)benzodi-azepines and benzodiazocines
DE2424811C3 (de) *	1974-05-22	1981-08-20	Dr. Karl Thomae Gmbh, 7950 Biberach	Pyrido-benzodiazepinone, Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel
SE422799B (sv) *	1975-05-28	1982-03-29	Merck & Co Inc	Analogiforfarande for framstellning av 1,3-dihydroimidazo (4,5-b)pyridin-2-oner

1981
- 1981-11-05 SE SE8106573A patent/SE448629B/sv not_active IP Right Cessation
- 1981-11-12 NO NO813839A patent/NO157700C/no unknown
- 1981-11-12 ZA ZA817866A patent/ZA817866B/xx unknown
- 1981-11-13 IN IN1261/CAL/81A patent/IN156080B/en unknown
- 1981-11-13 IL IL64284A patent/IL64284A/xx unknown
- 1981-11-17 GR GR66553A patent/GR78473B/el unknown
- 1981-11-18 PH PH26507A patent/PH17847A/en unknown
- 1981-11-25 IE IE2769/81A patent/IE52493B1/en unknown
- 1981-12-09 IT IT68605/81A patent/IT1146728B/it active
- 1981-12-10 FI FI813976A patent/FI71935C/fi not_active IP Right Cessation
- 1981-12-15 ES ES507971A patent/ES8303348A1/es not_active Expired
- 1981-12-15 HU HU813777A patent/HU187393B/hu not_active IP Right Cessation
- 1981-12-15 HU HU843212A patent/HU189426B/hu not_active IP Right Cessation
- 1981-12-21 DE DE19813150522 patent/DE3150522A1/de not_active Withdrawn
- 1981-12-23 PL PL1981253538A patent/PL143596B1/pl unknown
- 1981-12-23 PL PL1981241409A patent/PL139381B1/pl unknown
- 1981-12-23 FR FR8124111A patent/FR2515183B1/fr not_active Expired
- 1981-12-23 PL PL1981253540A patent/PL143322B1/pl unknown
- 1981-12-23 PL PL1981253539A patent/PL143597B1/pl unknown
- 1981-12-23 PL PL1981241410A patent/PL137068B1/pl unknown
- 1981-12-23 PL PL1981234426A patent/PL138859B1/pl unknown
- 1981-12-30 BE BE0/206969A patent/BE891666A/fr not_active IP Right Cessation
1982
- 1982-01-05 LU LU83865A patent/LU83865A1/fr unknown
- 1982-01-12 EG EG11/82A patent/EG15904A/xx active
- 1982-01-14 JP JP57004813A patent/JPS5865290A/ja active Pending
- 1982-01-15 PT PT74286A patent/PT74286B/pt unknown
- 1982-01-18 CA CA000394367A patent/CA1199324A/en not_active Expired
- 1982-02-02 KR KR8200420A patent/KR890000764B1/ko not_active Expired
- 1982-02-12 NL NL8200549A patent/NL8200549A/nl not_active Application Discontinuation
- 1982-02-18 NZ NZ198999A patent/NZ198999A/en unknown
- 1982-03-23 YU YU62582A patent/YU46128B/sh unknown
- 1982-04-15 CH CH2288/82A patent/CH651833A5/fr not_active IP Right Cessation
- 1982-04-26 DK DK186282A patent/DK186282A/da not_active Application Discontinuation
- 1982-09-29 ES ES516051A patent/ES8308563A1/es not_active Expired
- 1982-09-29 ES ES516052A patent/ES516052A0/es active Granted
1983
- 1983-10-19 ES ES526562A patent/ES526562A0/es active Granted
- 1983-10-19 ES ES526563A patent/ES8604531A1/es not_active Expired
1984
- 1984-08-17 PH PH31120A patent/PH20536A/en unknown
1985
- 1985-05-21 ES ES543328A patent/ES8607726A1/es not_active Expired
1986
- 1986-02-17 SE SE8600688A patent/SE455305B/sv not_active IP Right Cessation
1987
- 1987-08-03 DK DK403387A patent/DK403387A/da not_active Application Discontinuation
- 1987-08-03 DK DK403487A patent/DK403487D0/da not_active Application Discontinuation

Also Published As

Publication number	Publication date
ES8504148A1 (es)	1985-04-01
HU189426B (en)	1986-07-28
NO813839L (no)	1983-03-25
PL143597B1 (en)	1988-02-29
ES526562A0 (es)	1985-04-01
ES543328A0 (es)	1986-06-01
IN156080B (da)	1985-05-11
PL143596B1 (en)	1988-02-29
IL64284A0 (en)	1982-02-28
IL64284A (en)	1986-12-31
LU83865A1 (fr)	1983-09-02
NZ198999A (en)	1987-07-31
ES8604531A1 (es)	1986-02-01
NL8200549A (nl)	1983-04-18
PL143322B1 (en)	1988-02-29
NO157700B (no)	1988-01-25
ES8607726A1 (es)	1986-06-01
KR830009058A (ko)	1983-12-17
NO157700C (no)	1988-05-04
IE52493B1 (en)	1987-11-25
FI71935B (fi)	1986-11-28
IE812769L (en)	1983-03-24
DK403487A (da)	1987-08-03
ES516051A0 (es)	1983-09-16
SE8106573L (sv)	1983-03-25
IT8168605A0 (it)	1981-12-09
SE8600688L (sv)	1986-02-17
HUT34732A (en)	1985-04-28
ES507971A0 (es)	1983-02-01
PT74286B (en)	1983-06-27
EG15904A (en)	1987-03-30
YU62582A (en)	1986-04-30
DE3150522A1 (de)	1983-04-07
PT74286A (en)	1982-02-01
PL234426A1 (en)	1984-01-02
JPS5865290A (ja)	1983-04-18
ES8308563A1 (es)	1983-09-16
PL241409A1 (en)	1984-05-21
CH651833A5 (fr)	1985-10-15
ES8303348A1 (es)	1983-02-01
DK403387D0 (da)	1987-08-03
HU187393B (en)	1985-12-28
SE8600688D0 (sv)	1986-02-17
PL137068B1 (en)	1986-04-30
ZA817866B (en)	1982-10-27
KR890000764B1 (ko)	1989-04-05
ES8402295A1 (es)	1984-01-16
DK403387A (da)	1987-08-03
DK186282A (da)	1983-03-25
FR2515183B1 (fr)	1986-11-14
BE891666A (fr)	1982-04-16
PL138859B1 (en)	1986-11-29
SE448629B (sv)	1987-03-09
PL139381B1 (en)	1987-01-31
SE455305B (sv)	1988-07-04
ES516052A0 (es)	1984-01-16
DK403487D0 (da)	1987-08-03
FI71935C (fi)	1987-03-09
IT1146728B (it)	1986-11-19
ES526563A0 (es)	1986-02-01
PH17847A (en)	1985-01-09
FR2515183A1 (fr)	1983-04-29
PH20536A (en)	1987-02-09
PL241410A1 (en)	1984-01-02
CA1199324A (en)	1986-01-14
GR78473B (da)	1984-09-27
FI813976L (fi)	1983-03-25

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YU46915B (sh)	1994-06-24	Postupak za dobijanje kalcijum nezavisnih camp inhibitora fosfodiesteraze
BR9611618A (pt)	1999-03-30	Composto processo para sua preparação composição farmacêutica e utilização de um compostos
CY1252A (en)	1984-08-31	(piperidinylalkyl)quinazoline derivatives and intermediates,process for their preparation and pharmaceutical compositions containing them
YU64092A (sh)	1995-03-27	Fluoralkoksibenzamino derivati heterocikličnih jedinjenja koja sadrže azot
PL313075A1 (en)	1996-05-27	Heterocyclic compounds used as antagonistic substances in respect to neurokinin
ATE121389T1 (de)	1995-05-15	Ringverknüpfte analoge von stickstoffenthaltenden nichtaromatischen heterocyclen.
NZ333706A (en)	2000-08-25	Benzenesulfone derivatives and medicaments
IL57577A0 (en)	1979-10-31	1,2-dihydroquinolin-2-one derivatives,process for their preparation and pharmaceutical compositions containing the same
YU25593A (sh)	1996-10-09	Derivati acilaminoindola
DK173783D0 (da)	1983-04-20	Fremgangsmade til fremstilling af imidazo (1,2-alfa)pyridiner
DK0698025T3 (da)	1998-08-24	Ampa-antagonister samt fremgangsmåde til behandling dermed
YU86091A (sh)	1993-11-16	Postupak za izradu stabilnih smeša bitumen-polimera
ES8300745A1 (es)	1982-11-01	Un procedimiento para la preparacion de nuevos derivados de la quinoleina.
YU45827B (sh)	1992-07-20	Novi 6-ili 7-metilenandrosta-1-4-dien-3,17-dionski derivati i postupak za njihovo dobijanje
YU46128B (sh)	1993-05-28	Postupak za dobivanje fenil supstituisanih pirido (1,4) benzodiazepina
YU45884B (sh)	1992-09-07	Postupak za dobivanje supstituisanih penem derivata
AR017097A1 (es)	2001-08-22	Compuestos de 2-(3h)-oxazolona, utiles como inhibidores selectivos de cox-2; procedimiento para preparar dichos compuestos y composiciones farmaceuticasformuladas con dichos compuestos
YU48424B (sh)	1998-07-10	Postupak za dobijanje 4-supstituisanih-1,4-dihidropiridina
EA199900043A1 (ru)	1999-06-24	ПРОИЗВОДНЫЕ ПИРИДИЛКАРБАМОИЛИНДОЛИНОВ В КАЧЕСТВЕ АНТАГОНИСТОВ 5-НТ2с-РЕЦЕПТОРОВ
ES527739A0 (es)	1985-04-16	Un procedimiento para preparar derivados de pirimidina
FR2396015A1 (fr)	1979-01-26	Derives de l'acetylene, leur procede de preparation et leur utilisation comme inhibiteurs de monoamine-oxydases pour traiter notamment un etat depressif ou de l'hypertension
ATE585T1 (de)	1982-02-15	N-azolylessigsaeureanilide, verfahren zu ihrer herstellung und ihre anwendung als herbizide.
FR2392020A1 (fr)	1978-12-22	Nouvelles amidines, leur procede de preparation et leur utilisation comme anti-inflammatoires
JPS545934A (en)	1979-01-17	4-(4'-alkoxybenzoyloxy)-aniline derivatives, process for their preparation and their use
YU47020B (sh)	1994-11-15	Postupak za dobijanje 6-beta(supstituisanih)-(s)-hidroksimetil-penicilan skih kiselina i njihovih derivata