ZA824218B - Plasmid for producing human insulin - Google Patents

Plasmid for producing human insulin

Info

Publication number: ZA824218B
Authority: ZA; South Africa
Prior art keywords: plasmid; human insulin; producing human; producing; insulin
Prior art date: 1981-06-29

Application number

ZA824218A

Other languages

English (en)

Inventor

C Bahl

Original Assignee

Cetus Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1981-06-29

Filing date

1982-06-15

Publication date

1983-04-27

1982-06-15 Application filed by Cetus Corp filed Critical Cetus Corp

1983-04-27 Publication of ZA824218B publication Critical patent/ZA824218B/xx

Links

101000976075 Homo sapiens Insulin Proteins 0.000 title 1
PBGKTOXHQIOBKM-FHFVDXKLSA-N insulin (human) Chemical compound C([C@@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@H]1CSSC[C@H]2C(=O)N[C@H](C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@H](C(N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC=3C=CC(O)=CC=3)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC=3C=CC(O)=CC=3)C(=O)N[C@@H](CSSC[C@H](NC(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC=3C=CC(O)=CC=3)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC=3NC=NC=3)NC(=O)[C@H](CO)NC(=O)CNC1=O)C(=O)NCC(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)NCC(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CC=1C=CC(O)=CC=1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(O)=O)C(=O)N[C@@H](CC(N)=O)C(O)=O)=O)CSSC[C@@H](C(N2)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C(C)C)NC(=O)[C@@H](NC(=O)CN)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](NC(=O)[C@@H](N)CC=1C=CC=CC=1)C(C)C)C1=CN=CN1 PBGKTOXHQIOBKM-FHFVDXKLSA-N 0.000 title 1
239000013612 plasmid Substances 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/62—DNA sequences coding for fusion proteins
- C12N15/625—DNA sequences coding for fusion proteins containing a sequence coding for a signal sequence
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/62—Insulins
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
- C07K2319/74—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
- C07K2319/75—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones

Landscapes

Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Organic Chemistry (AREA)
Zoology (AREA)
Biomedical Technology (AREA)
Molecular Biology (AREA)
Biophysics (AREA)
Biochemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
General Health & Medical Sciences (AREA)
Wood Science & Technology (AREA)
General Engineering & Computer Science (AREA)
Biotechnology (AREA)
Physics & Mathematics (AREA)
Microbiology (AREA)
Plant Pathology (AREA)
Diabetes (AREA)
Endocrinology (AREA)
Toxicology (AREA)
Gastroenterology & Hepatology (AREA)
Medicinal Chemistry (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Peptides Or Proteins (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)

ZA824218A 1981-06-29 1982-06-15 Plasmid for producing human insulin ZA824218B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US27833181A	1981-06-29	1981-06-29

Publications (1)

Publication Number	Publication Date
ZA824218B true ZA824218B (en)	1983-04-27

Family

ID=23064574

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA824218A ZA824218B (en)	1981-06-29	1982-06-15	Plasmid for producing human insulin

Country Status (12)

Country	Link
US (1)	USH245H (fr)
EP (1)	EP0070632A3 (fr)
JP (1)	JPS58501227A (fr)
AU (1)	AU556980B2 (fr)
CA (1)	CA1201074A (fr)
DK (1)	DK84583A (fr)
ES (1)	ES8304430A1 (fr)
IL (1)	IL66102A0 (fr)
NO (1)	NO830682L (fr)
PT (1)	PT75075B (fr)
WO (1)	WO1983000164A1 (fr)
ZA (1)	ZA824218B (fr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0090433A1 (fr) *	1982-03-31	1983-10-05	Genetics Institute, Inc.	Création des séquences d'ADN codant des précurseurs de proinsuline modifiée
DE3245665A1 (de) *	1982-05-04	1983-11-10	Boehringer Mannheim Gmbh, 6800 Mannheim	Verfahren zur herstellung permanenter tierischer und humaner zellinien und deren verwendung
US5670371A (en) *	1983-07-15	1997-09-23	Bio-Technology General Corp.	Bacterial expression of superoxide dismutase
DK58285D0 (da) *	1984-05-30	1985-02-08	Novo Industri As	Peptider samt fremstilling og anvendelse deraf
US4767709A (en)	1984-06-28	1988-08-30	The Johns Hopkins University	Growth-related hormones
PH25772A (en) *	1985-08-30	1991-10-18	Novo Industri As	Insulin analogues, process for their preparation
US5496924A (en) *	1985-11-27	1996-03-05	Hoechst Aktiengesellschaft	Fusion protein comprising an interleukin-2 fragment ballast portion
DE3752347T2 (de) *	1986-05-20	2002-09-26	The General Hospital Corp., Boston	Verfahren zur pharmakokinetischen Studie der Insulin-Expression mit nicht-menschlichem Transgen-Säugetier
US6348327B1 (en) *	1991-12-06	2002-02-19	Genentech, Inc.	Non-endocrine animal host cells capable of expressing variant proinsulin and processing the same to form active, mature insulin and methods of culturing such cells
US6001604A (en) *	1993-12-29	1999-12-14	Bio-Technology General Corp.	Refolding of proinsulins without addition of reducing agents
US20180057920A1 (en) *	2016-08-31	2018-03-01	General Electric Company	Grain refinement in in706 using laves phase precipitation

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS5210872B2 (fr) *	1973-07-14	1977-03-26
US4082613A (en) *	1976-04-23	1978-04-04	The Regents Of The University Of Minnesota	Process for the production of insulin by genetically transformed fungal cells
US4411994A (en) *	1978-06-08	1983-10-25	The President And Fellows Of Harvard College	Protein synthesis
FI792481A7 (fi) *	1978-08-11	1981-01-01	The Regents Of The Univ Of	Enkaroyyttisen proteiinin synteesi mikro-organismia käyttäen.
GR70279B (fr) *	1979-09-12	1982-09-03	Univ California
DE3001928A1 (de) *	1980-01-19	1981-08-06	Hoechst Ag, 6000 Frankfurt	Genprodukt eines hoeheren organismus aus einem dieses gen enthaltenden mikroorganismus
EP0036258A3 (fr)	1980-03-14	1982-02-10	Cetus Corporation	Procédé pour la production d'aspartame
US4338397A (en) *	1980-04-11	1982-07-06	President And Fellows Of Harvard College	Mature protein synthesis
DK582381A (da) *	1981-01-02	1982-07-03	Univ New York	Remkombinat plasmid til anvendelse ved bakteriel kloning

1982
- 1982-06-15 ZA ZA824218A patent/ZA824218B/xx unknown
- 1982-06-18 PT PT75075A patent/PT75075B/pt unknown
- 1982-06-21 IL IL66102A patent/IL66102A0/xx unknown
- 1982-06-25 WO PCT/US1982/000858 patent/WO1983000164A1/fr not_active Ceased
- 1982-06-25 EP EP82303340A patent/EP0070632A3/fr not_active Withdrawn
- 1982-06-25 JP JP57502369A patent/JPS58501227A/ja active Pending
- 1982-06-25 AU AU87623/82A patent/AU556980B2/en not_active Ceased
- 1982-06-28 ES ES513522A patent/ES8304430A1/es not_active Expired
- 1982-06-29 CA CA000406245A patent/CA1201074A/fr not_active Expired
1983
- 1983-02-24 DK DK84583A patent/DK84583A/da not_active Application Discontinuation
- 1983-02-28 NO NO830682A patent/NO830682L/no unknown
1984
- 1984-06-27 US US06/625,176 patent/USH245H/en not_active Abandoned

Also Published As

Publication number	Publication date
PT75075A (en)	1982-07-01
WO1983000164A1 (fr)	1983-01-20
USH245H (en)	1987-04-07
ES513522A0 (es)	1983-03-01
PT75075B (en)	1983-12-28
IL66102A0 (en)	1982-09-30
EP0070632A2 (fr)	1983-01-26
NO830682L (no)	1983-02-28
AU8762382A (en)	1983-02-02
AU556980B2 (en)	1986-11-27
CA1201074A (fr)	1986-02-25
ES8304430A1 (es)	1983-03-01
DK84583D0 (da)	1983-02-24
JPS58501227A (ja)	1983-07-28
EP0070632A3 (fr)	1983-06-29
DK84583A (da)	1983-02-24

Publication	Publication Date	Title
GB2156220B (en)	1987-08-05	Improved cannula
DE3277399D1 (en)	1987-11-05	Medical electrode
GB2098440B (en)	1985-06-26	Medical apparatus
DE3279371D1 (en)	1989-02-23	Plasmid
GB2094256B (en)	1984-08-22	Controlled delivery capsule
AU7914581A (en)	1982-07-08	Human proinsulin, insulin, preparation thereof
GB2116042B (en)	1985-03-06	Injector for medical uses
JPS57195454A (en)	1982-12-01	Handpiece
DE3565468D1 (en)	1988-11-17	Drug administering apparatus
GB2091107B (en)	1984-09-05	Dental syringe
AU556980B2 (en)	1986-11-27	Plasmid for producing human insulin
GB2164566B (en)	1988-04-27	Powered infusion apparatus
GB2160323B (en)	1987-12-09	Tomography
GB8311420D0 (en)	1983-06-02	Insulin formulations
GB2090535B (en)	1984-09-19	Medical inserts
JPS57139016A (en)	1982-08-27	Burn patient medicine
GB2104380B (en)	1984-12-05	Human proinsulin pharmaceutical formulations
JPS57123120A (en)	1982-07-31	Novel insulin medicine
GB8407044D0 (en)	1984-04-26	Producing human insulin
IE821553L (en)	1982-12-29	Plasmids for producing human insulin
GB2071223B (en)	1983-12-07	Medical infusion system
JPS57173061A (en)	1982-10-25	Medical material
IE812104L (en)	1982-06-29	Novel insulin formulations based on human insulin
DE3273470D1 (en)	1986-10-30	Process for preparing human insulin or b-30 esters thereof
IE860656L (en)	1981-09-24	Expression plasmid