ZA837603B - Immunogenic protein or peptide complex,method of producing said complex and the use thereof as an immune stimulant and as a vaccine - Google Patents

Immunogenic protein or peptide complex,method of producing said complex and the use thereof as an immune stimulant and as a vaccine

Info

Publication number
ZA837603B
ZA837603B ZA837603A ZA837603A ZA837603B ZA 837603 B ZA837603 B ZA 837603B ZA 837603 A ZA837603 A ZA 837603A ZA 837603 A ZA837603 A ZA 837603A ZA 837603 B ZA837603 B ZA 837603B
Authority
ZA
South Africa
Prior art keywords
complex
vaccine
producing
immunogenic protein
immune stimulant
Prior art date
Application number
ZA837603A
Other languages
English (en)
Inventor
Bror Morein
Original Assignee
Bror Morein
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bror Morein filed Critical Bror Morein
Publication of ZA837603B publication Critical patent/ZA837603B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/806—Antigenic peptides or proteins

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
ZA837603A 1982-10-18 1983-10-12 Immunogenic protein or peptide complex,method of producing said complex and the use thereof as an immune stimulant and as a vaccine ZA837603B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE8205892A SE8205892D0 (sv) 1982-10-18 1982-10-18 Immunogent membranproteinkomplex, sett for framstellning och anvendning derav som immunstimulerande medel och sasom vaccin

Publications (1)

Publication Number Publication Date
ZA837603B true ZA837603B (en) 1984-12-24

Family

ID=20348235

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA837603A ZA837603B (en) 1982-10-18 1983-10-12 Immunogenic protein or peptide complex,method of producing said complex and the use thereof as an immune stimulant and as a vaccine

Country Status (18)

Country Link
US (2) US4578269A (fr)
EP (1) EP0109942B1 (fr)
JP (1) JPH07112983B2 (fr)
AR (1) AR243080A1 (fr)
AT (1) ATE61228T1 (fr)
AU (1) AU558258B2 (fr)
CA (1) CA1243954A (fr)
DE (2) DE109942T1 (fr)
DK (1) DK162057C (fr)
ES (1) ES526524A0 (fr)
FI (1) FI80600C (fr)
IE (1) IE57025B1 (fr)
MX (1) MX7563E (fr)
NO (1) NO163668C (fr)
NZ (1) NZ205925A (fr)
PT (1) PT77515B (fr)
SE (1) SE8205892D0 (fr)
ZA (1) ZA837603B (fr)

Families Citing this family (310)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4804624A (en) * 1982-05-21 1989-02-14 The University Of Tennessee Research Corporation Passive agglutination assay for pseudorabies antibody
SE8205892D0 (sv) * 1982-10-18 1982-10-18 Bror Morein Immunogent membranproteinkomplex, sett for framstellning och anvendning derav som immunstimulerande medel och sasom vaccin
US4770874A (en) * 1983-08-22 1988-09-13 Syntex (U.S.A.) Inc. Polyoxypropylene-polyoxyethylene block polymer based adjuvants
US4772466A (en) * 1983-08-22 1988-09-20 Syntex (U.S.A.) Inc. Vaccines comprising polyoxypropylene-polyoxyethylene block polymer based adjuvants
US6090406A (en) * 1984-04-12 2000-07-18 The Liposome Company, Inc. Potentiation of immune responses with liposomal adjuvants
US5916588A (en) * 1984-04-12 1999-06-29 The Liposome Company, Inc. Peptide-containing liposomes, immunogenic liposomes and methods of preparation and use
SE8402861L (sv) * 1984-05-28 1985-11-29 Stefan Svenson Rening av biologiskt material
NL8403195A (nl) * 1984-10-19 1986-05-16 Nederlanden Staat Immunogene complexen en vaccins die deze bevatten.
SE8405493D0 (sv) * 1984-11-01 1984-11-01 Bror Morein Immunogent komplex samt sett for framstellning derav och anvendning derav som immunstimulerande medel
JPH0832637B2 (ja) * 1985-02-14 1996-03-29 アクゾ・エヌ・ヴエー 合成免疫原
US4683294A (en) * 1985-04-03 1987-07-28 Smith Kline Rit, S.A. Process for the extraction and purification of proteins from culture media producing them
US4871488A (en) * 1985-04-22 1989-10-03 Albany Medical College Of Union University Reconstituting viral glycoproteins into large phospholipid vesicles
US4631191A (en) * 1985-06-20 1986-12-23 Biotechnology Research Partners, Ltd. Methods and compositions useful in preventing equine influenza
ATE71303T1 (de) * 1986-01-14 1992-01-15 Nederlanden Staat Verfahren zur herstellung immunologischer komplexe und diese enthaltende pharmazeutische zusammensetzung.
US4981685A (en) * 1986-03-07 1991-01-01 Utah State University Foundation Bacterial extract vaccines for veterinary application
US4806350A (en) * 1986-04-18 1989-02-21 Norden Laboratories, Inc. Vaccine formulation
CA1331355C (fr) * 1986-04-21 1994-08-09 Bioenterprises Pty. Ltd Immunopotentialisation
ZA872203B (en) * 1986-04-28 1988-02-24 New York Blood Center Inc Complex immunogen containing synthetic peptides
JPH0789951B2 (ja) * 1986-06-18 1995-10-04 財団法人阪大微生物病研究会 遺伝子発現産物の精製法
US5374426A (en) * 1986-09-03 1994-12-20 University Of Saskatchewan Rotavirus nucleocapsid protein VP6 in vaccine compositions
US5190859A (en) * 1987-02-26 1993-03-02 Dana-Farber Cancer Institute, Inc. Purification of LFA-3
US5026828A (en) * 1987-02-27 1991-06-25 Merck & Co., Inc. Method of purifying recombinant pres-1/S-2/S/S hepatitis B antigen from yeast
US5976839A (en) * 1987-03-13 1999-11-02 Bioenterprises Pty Limited Immunopotentiation through covalent linkage between immunogen and immunopotentiating molecules
US4888416A (en) * 1987-03-30 1989-12-19 International Minerals & Chemical Corp. Method for stabilizing somatotropins
US5583112A (en) * 1987-05-29 1996-12-10 Cambridge Biotech Corporation Saponin-antigen conjugates and the use thereof
US5043158A (en) * 1987-08-21 1991-08-27 Chembiomed, Ltd. Immunogenic compositions containing ordered carriers
US5011915A (en) * 1987-10-26 1991-04-30 Merck & Co., Inc. Process for purifying recombinant hepatitis antigens
ATE118348T1 (de) * 1987-12-04 1995-03-15 Liposome Co Inc Liposome hoher stabilität und verfahren zur herstellung und verwendung.
AU3048689A (en) * 1988-01-13 1989-08-11 University Of North Carolina At Chapel Hill, The Immunogenic peptides
US5039522A (en) * 1988-01-29 1991-08-13 New York Blood Center, Inc. Immunogens containing peptides with an attached hydrophobic tail for adsorption to hepatitis B virus surface antigen
US5885589A (en) * 1988-04-12 1999-03-23 Intervet International B.V. Pasteurella vaccine
DK199588D0 (da) * 1988-04-12 1988-04-12 Nordisk Droge & Kemikalie Vaccine
EP0372056A4 (en) * 1988-05-04 1991-05-15 Dana Farber Cancer Institute Protein micelles
US5071964A (en) * 1988-05-04 1991-12-10 Dana-Farber Cancer Institute, Inc. Protein micelles
US6291228B1 (en) * 1988-08-03 2001-09-18 Vericore Limited Vaccine
GB8818415D0 (en) * 1988-08-03 1988-09-07 Animal Health Inst Vaccine
JPH0292996A (ja) * 1988-09-30 1990-04-03 Bror Morein アジュバントおよび脂質を含む複合体
NZ230747A (en) * 1988-09-30 1992-05-26 Bror Morein Immunomodulating matrix comprising a complex of at least one lipid and at least one saponin; certain glycosylated triterpenoid saponins derived from quillaja saponaria molina
US4981684A (en) * 1989-10-24 1991-01-01 Coopers Animal Health Limited Formation of adjuvant complexes
ES2100892T3 (es) * 1989-09-15 1997-07-01 Tanox Biosystems Inc Tratamiento de enfermedades autoinmunitarias.
NL9002314A (nl) * 1990-10-23 1992-05-18 Nederlanden Staat Immunogene complexen, in het bijzonder iscoms.
IT1248075B (it) * 1991-06-18 1995-01-05 Sclavo Spa Processo per la purificazione del virus dell'epatite a (hav), virus cosi` purificato e composizioni vaccinali che lo contengono.
GB9200117D0 (en) * 1992-01-06 1992-02-26 Connaught Lab Production of recombinant chimeric proteins for vaccine use
DE4220653A1 (de) * 1992-06-26 1994-01-13 Boehringer Mannheim Gmbh Verfahren und Mittel zum Nachweis eines Analyten enthaltend glykosidische Tenside
EP0604727A1 (fr) * 1992-12-31 1994-07-06 American Cyanamid Company Immunogénéité améliorée d'un vaccin par incorporation d'un cytocine dans un complexe immunostimulant contenant un antigène
PT716697E (pt) * 1993-09-03 2003-08-29 Univ Mcgill Genes e proteinas de leishmania expressos diferencialmente
US5773011A (en) * 1993-09-27 1998-06-30 Gerbu Biotechnik Gmbh Method of preparing a synergistic immunological adjuvant formulation
GB9320597D0 (en) * 1993-10-06 1993-11-24 Proteus Molecular Design Improvements in and realting to vaccines
US6083513A (en) * 1993-11-16 2000-07-04 Gerbu Biotechnik Gmbh Method for increasing the yield of antibodies in the techniques of immunology
US6207646B1 (en) 1994-07-15 2001-03-27 University Of Iowa Research Foundation Immunostimulatory nucleic acid molecules
AU4369596A (en) * 1994-11-21 1996-06-17 Virginia L. Scofield Sperm as vaccine vectors
DK0805855T3 (da) * 1995-01-27 2007-06-25 Genencor Int Overfladeaktivt middel-baseret enzymekstraktionsproces
WO1996040233A1 (fr) * 1995-06-07 1996-12-19 Pfizer Inc. Vaccination in ovo contre la coccidiose
US6500438B2 (en) 1995-06-07 2002-12-31 Pfizer Incorporated In ovo vaccination against coccidiosis
ZA97452B (en) 1996-01-25 1997-08-15 Trinity College Dublin Streptococcus equi vaccine.
GB9618119D0 (en) 1996-08-30 1996-10-09 Univ Southampton Adjuvants for use in vaccines
ZA9710606B (en) * 1996-12-05 1998-06-12 Akzo Nobel Nv Non-virulent Mycoplasma synoviae vaccine thereof.
US6406705B1 (en) * 1997-03-10 2002-06-18 University Of Iowa Research Foundation Use of nucleic acids containing unmethylated CpG dinucleotide as an adjuvant
AUPO732997A0 (en) 1997-06-12 1997-07-03 Csl Limited Ganglioside immunostimulating complexes and uses thereof
US6455323B1 (en) 1997-07-03 2002-09-24 Pharmacia & Upjohn Company Anti-bacterial methods and materials
US6627205B2 (en) 1997-12-01 2003-09-30 Pfizer Incorporated Ovo vaccination against coccidiosis
US6495140B1 (en) 1998-01-12 2002-12-17 Her Majesty In Right Of Canada As Represented By The Minister Of Agriculture And Agri-Food Canada Process for the isolation, recovery and purification of non-polar extractives
US6908770B1 (en) * 1998-07-16 2005-06-21 Board Of Regents, The University Of Texas System Fluid based analysis of multiple analytes by a sensor array
US20010033839A1 (en) * 1999-10-04 2001-10-25 Emilio Barbera-Guillem Vaccine and immunotherapy for solid nonlymphoid tumor and related immune dysregulation
GB2348203B (en) 1998-11-04 2002-06-19 Imp College Innovations Ltd Solube beta-forms of prion proteins, methods of preparation and use
ES2572834T3 (es) * 1999-02-17 2016-06-02 Csl Limited Complejos inmunogénicos y métodos relacionados con los mismos
US6984378B1 (en) 1999-02-26 2006-01-10 Pfizer, Inc. Method for the purification, recovery, and sporulation of cysts and oocysts
US6790950B2 (en) 1999-04-09 2004-09-14 Pharmacia & Upjohn Company Anti-bacterial vaccine compositions
HK1045856A1 (zh) 1999-04-09 2002-12-13 法玛西雅厄普约翰美国公司 抗细菌疫苗组合物
US6558670B1 (en) 1999-04-19 2003-05-06 Smithkline Beechman Biologicals S.A. Vaccine adjuvants
PT1187629E (pt) 1999-04-19 2005-02-28 Glaxosmithkline Biolog Sa Composicao adjuvante que compreende saponina e um oligonucleotido imunoestimulador
PL355287A1 (en) * 1999-09-24 2004-04-05 Smithkline Beecham Biologicals S.A. Intranasal influenza virus vaccine
NZ520976A (en) * 1999-11-19 2005-01-28 Csl Ltd Vaccine compositions
DE60112413T2 (de) 2000-03-17 2006-06-01 Pharmacia & Upjohn Co. Llc, Kalamazoo Ssa inaktivierte salmonella impfstoffe
WO2001077365A2 (fr) 2000-04-06 2001-10-18 Pharmacia & Upjohn Company Procedes et materiaux antimicrobiens
US7323174B1 (en) 2000-06-12 2008-01-29 Arizona Board Of Regents On Behalf Of The University Of Arizona Modulation of immune response and methods based thereon
AU2002244337B2 (en) * 2000-10-18 2005-08-11 Glaxosmithkline Biologicals S.A. Vaccines
SI2266603T1 (sl) 2000-10-18 2012-12-31 Glaxosmithkline Biologicals S.A. Tumorska cepiva
EP2281573A3 (fr) 2001-02-23 2011-12-07 GlaxoSmithKline Biologicals s.a. Formulations de vaccins contre la grippe dispositif pour administration intradermique
US7713942B2 (en) * 2001-04-04 2010-05-11 Nordic Vaccine Technology A/S Cage-like microparticle complexes comprising sterols and saponins for delivery of polynucleotides
WO2002080981A2 (fr) 2001-04-04 2002-10-17 Nordic Vaccine Technology A/S Complexes de liaison de polynucleotides comprenant des sterols et des saponines
GB0109297D0 (en) 2001-04-12 2001-05-30 Glaxosmithkline Biolog Sa Vaccine
GB0112126D0 (en) 2001-05-18 2001-07-11 Allergene Inc Composition
MY134424A (en) 2001-05-30 2007-12-31 Saechsisches Serumwerk Stable influenza virus preparations with low or no amount of thiomersal
US20100221284A1 (en) 2001-05-30 2010-09-02 Saech-Sisches Serumwerk Dresden Novel vaccine composition
JP4104548B2 (ja) 2001-08-30 2008-06-18 エンブレクス，インコーポレイテッド 接合子嚢を生成するための改良方法
SE0202110D0 (sv) * 2002-07-05 2002-07-05 Isconova Ab Iscom preparation and use thereof
WO2004018683A1 (fr) 2002-08-12 2004-03-04 Akzo Nobel N.V. Proteine streptococcus uberis, sequence d'acide nucleique codant pour cette proteine et utilisation de cette derniere dans un vaccin contre la mammite
HUE031886T2 (en) 2002-10-11 2017-08-28 Glaxosmithkline Biologicals Sa Polypeptide vaccines for extensive protection against hypervirulent meningococcal lines
US7125425B2 (en) * 2002-10-21 2006-10-24 Sdgi Holdings, Inc. Systems and techniques for restoring and maintaining intervertebral anatomy
AU2003296592A1 (en) 2002-11-20 2004-06-15 Crucell Holland B.V. Antigen-complexes
US7491395B2 (en) 2002-11-20 2009-02-17 Bestewil Holding B.V. Compositions comprising antigen-complexes, method of making same as well as methods of using the antigen-complexes for vaccination
EP2172213B1 (fr) 2003-01-30 2013-04-03 Novartis AG Vaccins injectables contre les multiples serogroupes du meningocoque
AR056245A1 (es) 2003-06-19 2007-10-03 Bestewil Holding Bv Membranas virales reconstituidas funcionales que contienen un coadyuvante
US9023366B2 (en) 2003-07-01 2015-05-05 The Royal Veterinary College Vaccine composition for vaccinating dogs against canine infectious respiratory disease (CIRD)
GB0315323D0 (en) 2003-07-01 2003-08-06 Royal Veterinary College Vaccine composition
SE0301998D0 (sv) 2003-07-07 2003-07-07 Isconova Ab Quil A fraction with low toxicity and use thereof
ES2505695T3 (es) 2003-07-31 2014-10-10 Novartis Vaccines And Diagnostics, Inc. Composiciones inmunógenas para Streptococcus pyogenes
GB0323103D0 (en) 2003-10-02 2003-11-05 Chiron Srl De-acetylated saccharides
NZ546430A (en) 2003-10-02 2009-04-30 Novartis Vaccines & Diagnostic Liquid vaccines for multiple meningococcal serogroups
JP5600375B2 (ja) 2004-03-09 2014-10-01 ノバルティス バクシンズ アンド ダイアグノスティックス，インコーポレーテッド インフルエンザウイルスワクチン
GB0500787D0 (en) 2005-01-14 2005-02-23 Chiron Srl Integration of meningococcal conjugate vaccination
GB0409745D0 (en) 2004-04-30 2004-06-09 Chiron Srl Compositions including unconjugated carrier proteins
NZ550533A (en) 2004-04-30 2010-02-26 Novartis Vaccines & Diagnostic Meningococcal conjugate vaccination comprising N. meningitidis and diphtheria toxin
GB0410866D0 (en) 2004-05-14 2004-06-16 Chiron Srl Haemophilius influenzae
EP2848692B1 (fr) 2004-05-21 2017-08-16 Novartis Vaccines and Diagnostics, Inc. Vecteurs d'alphavirus de vaccins contre le virus de la grippe
EP2269638A3 (fr) 2004-05-28 2012-06-13 GlaxoSmithKline Biologicals S.A. Compositions de vaccin comprenant des virosomes et un adjuvant à base de saponine
US20060287263A1 (en) * 2004-07-18 2006-12-21 Csl Limited Methods and compositions for inducing antigen-specific immune responses
JP2008508320A (ja) 2004-07-29 2008-03-21 カイロン コーポレイション Ｓｔｒｅｐｔｏｃｏｃｃｕｓａｇａｌａｃｔｉａｅのようなグラム陽性細菌に対する免疫原性組成物
CA2587084C (fr) 2004-10-08 2019-07-16 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services, Centers For Disease Control And Prevention Modulation de la valeur adaptative reproductive au moyen de codons synonymes employes moins frequemment
GB0424092D0 (en) 2004-10-29 2004-12-01 Chiron Srl Immunogenic bacterial vesicles with outer membrane proteins
US8007806B2 (en) 2005-01-20 2011-08-30 Isconova Ab Vaccine composition comprising a fibronectin binding protein or a fibronectin binding peptide
GB0502095D0 (en) 2005-02-01 2005-03-09 Chiron Srl Conjugation of streptococcal capsular saccharides
GB0503337D0 (en) 2005-02-17 2005-03-23 Glaxosmithkline Biolog Sa Compositions
SI1858920T1 (sl) 2005-02-18 2016-07-29 Glaxosmithkline Biologicals S.A. Proteini in nukleinske kisline iz escherichia coli, povezane z meningitisom/sepso
JP2008530245A (ja) 2005-02-18 2008-08-07 ノバルティス ヴァクシンズ アンド ダイアグノスティクス， インコーポレイテッド 尿路病原性菌株由来の抗原
GB0504436D0 (en) 2005-03-03 2005-04-06 Glaxosmithkline Biolog Sa Vaccine
WO2006133879A2 (fr) 2005-06-16 2006-12-21 Universiteit Gent Vaccins d'immunisation contre helicobacter
ES2357679T3 (es) 2005-07-28 2011-04-28 Pfizer Products Inc. VACUNA CONTRA CALICIVIRUS FELINO (FCV) QUE COMPRENDE UNA PROTEINA DE CAPSIDA DE UN FCV O UNA PROTEINA DE LA CAPSIDA DE UN FCV AISLADA QUE COMPRENDE UNA SECUENCIA PROTEICA SEC ID Nº: 13 O SECUENCIAS PROTEICAS CON, AL MENOS, 95% DE IDENTIDAD CON ELLA.
GB0519871D0 (en) 2005-09-30 2005-11-09 Secr Defence Immunogenic agents
ME00485B (me) 2005-10-07 2011-10-10 Zoetis Services Llc VAKCINE l METODE LIJEČENJA INFLUENCE KOD CANINA
CA2626253A1 (fr) 2005-10-18 2007-04-26 Novartis Vaccines And Diagnostics, Inc. Immunisations mucosiques et systemiques avec particules de replicon d'alphavirus
CA2628152C (fr) 2005-11-04 2016-02-02 Novartis Vaccines And Diagnostics S.R.L. Vaccins avec adjuvant comprenant des antigenes sans virions prepares a partir de virus influenza eleves en culture cellulaire
ES2514316T3 (es) 2005-11-22 2014-10-28 Novartis Vaccines And Diagnostics, Inc. Partículas similares a virus (VLPs) de Norovirus y Sapovirus
GB0524066D0 (en) 2005-11-25 2006-01-04 Chiron Srl 741 ii
GB0607088D0 (en) 2006-04-07 2006-05-17 Glaxosmithkline Biolog Sa Vaccine
KR101515078B1 (ko) 2005-12-22 2015-04-24 글락소스미스클라인 바이오로지칼즈 에스.에이. 백신
PL2478916T3 (pl) 2006-01-27 2020-11-16 Seqirus UK Limited Szczepionki przeciw grypie zawierające hemaglutyninę i białka macierzy
US8063063B2 (en) 2006-03-23 2011-11-22 Novartis Ag Immunopotentiating compounds
ES2536426T3 (es) 2006-03-23 2015-05-25 Novartis Ag Compuestos de imidazoquinoxalina como inmunomoduladores
CN101448523A (zh) 2006-03-24 2009-06-03 诺华疫苗和诊断有限两合公司 无需冷藏储存流感疫苗
EP2476433A1 (fr) 2006-03-30 2012-07-18 GlaxoSmithKline Biologicals S.A. Composition immunogène
EP2382988A1 (fr) 2006-03-31 2011-11-02 Novartis AG Immunisation mucosique et parentérale contre le VIH
PT2054431E (pt) 2006-06-09 2011-11-03 Novartis Ag Confórmeros de adesinas bacterianas
US8039007B2 (en) 2006-06-29 2011-10-18 J. Craig Venter Institute, Inc. Polypeptides from Neisseria meningitidis
US9364525B2 (en) 2006-07-18 2016-06-14 Glaxosmithkline Biologicals Sa Vaccines for malaria
GB0614460D0 (en) 2006-07-20 2006-08-30 Novartis Ag Vaccines
US8323664B2 (en) 2006-07-25 2012-12-04 The Secretary Of State For Defence Live vaccine strains of Francisella
EP2586790A3 (fr) 2006-08-16 2013-08-14 Novartis AG Immunogènes d'Escherischia coli pathogènes des voies urinaires
EP4585610A3 (fr) 2006-09-11 2025-09-24 Seqirus UK Limited Fabrication de vaccins contre le virus de la grippe sans utiliser d'oeufs
PL2068918T5 (pl) 2006-09-26 2024-12-02 Access To Advanced Health Institute Kompozycja szczepionki zawierająca syntetyczny adiuwant
US20090181078A1 (en) 2006-09-26 2009-07-16 Infectious Disease Research Institute Vaccine composition containing synthetic adjuvant
PT2121011E (pt) 2006-12-06 2014-07-31 Novartis Ag Vacinas compreendendo um antigénio a partir de quatro estirpes do vírus da gripe
CA2674026C (fr) 2006-12-27 2018-08-21 Pfizer Products Inc. Procedes d'administration de vaccin
GB0700562D0 (en) 2007-01-11 2007-02-21 Novartis Vaccines & Diagnostic Modified Saccharides
US20110097360A1 (en) 2007-05-25 2011-04-28 Claudio Donati Streptococcus pneumoniae pilus antigens
CA2690708A1 (fr) 2007-06-26 2008-12-31 Glaxosmithkline Biologicals S.A. Vaccin
KR20100045437A (ko) 2007-06-27 2010-05-03 노파르티스 아게 첨가물이 적은 인플루엔자 백신
GB0713880D0 (en) 2007-07-17 2007-08-29 Novartis Ag Conjugate purification
GB0714963D0 (en) 2007-08-01 2007-09-12 Novartis Ag Compositions comprising antigens
KR101621837B1 (ko) 2007-09-12 2016-05-17 노파르티스 아게 Ｇａｓ57 돌연변이 항원 및 ｇａｓ57 항체
EP2062594A1 (fr) 2007-11-21 2009-05-27 Wyeth Farma, S.A. Vaccin de la fièvre catarrhale du mouton et compositions immunogènes, procédé d'utilisation et son procédé de production
GB0810305D0 (en) 2008-06-05 2008-07-09 Novartis Ag Influenza vaccination
WO2009117035A1 (fr) 2007-12-19 2009-09-24 The Henry M. Jackson Foundation For The Advancement Of Military Medicine, Inc. Formes solubles de la glycoprotéine f des virus hendra et nipah et leurs utilisations
GB0818453D0 (en) 2008-10-08 2008-11-12 Novartis Ag Fermentation processes for cultivating streptococci and purification processes for obtaining cps therefrom
EP2537857B1 (fr) 2007-12-21 2017-01-18 GlaxoSmithKline Biologicals SA Formes mutantes de streptolysine O
JP5711972B2 (ja) 2007-12-24 2015-05-07 アイディー バイオメディカル コーポレイション オブ ケベック 組換えｒｓｖ抗原
CN102356089B (zh) 2008-02-21 2014-02-19 诺华股份有限公司 脑膜炎球菌fHBP多肽
JP5518041B2 (ja) 2008-03-18 2014-06-11 ノバルティス アーゲー インフルエンザウイルスワクチン抗原の調製における改良
PL2370099T3 (pl) 2008-12-09 2016-10-31 Zmodyfikowane białka F RSV i sposoby ich zastosowania
CN103897045A (zh) 2009-01-12 2014-07-02 诺华股份有限公司 抗革兰氏阳性细菌疫苗中的Cna_B结构域
GB0900455D0 (en) 2009-01-13 2009-02-11 Secr Defence Vaccine
GB0901423D0 (en) 2009-01-29 2009-03-11 Secr Defence Treatment
GB0901411D0 (en) 2009-01-29 2009-03-11 Secr Defence Treatment
PE20110992A1 (es) 2009-02-17 2012-02-12 Glaxosmithkline Biolog Sa Composicion inmunogenica que comprende un antigeno del virus del dengue
US8568732B2 (en) 2009-03-06 2013-10-29 Novartis Ag Chlamydia antigens
GB0906234D0 (en) 2009-04-14 2009-05-20 Secr Defence Vaccine
EP3263128A3 (fr) 2009-04-14 2018-01-24 GlaxoSmithKline Biologicals S.A. Compositions pour l'immunisation contre staphylococcus aureus
CA2764374C (fr) 2009-06-05 2019-11-19 Infectious Disease Research Institute Adjuvants lipidiques synthetiques a base de glucopyranosyle
DK2442826T3 (en) 2009-06-15 2015-09-21 Univ Singapore Influenza vaccine, composition and methods of using
EP2445527A2 (fr) 2009-06-24 2012-05-02 ID Biomedical Corporation of Quebec Vaccin
HUE028085T2 (en) 2009-06-24 2016-11-28 Glaxosmithkline Biologicals Sa Recombinant RSV antigens
CN102470168A (zh) * 2009-07-10 2012-05-23 伊斯克诺瓦公司 新组合物
CA2768186A1 (fr) 2009-07-15 2011-01-20 Novartis Ag Compositions a base de proteine f du vrs et procedes de fabrication associes
AU2010272243A1 (en) 2009-07-16 2012-03-08 Novartis Ag Detoxified Escherichia coli immunogens
GB0913680D0 (en) 2009-08-05 2009-09-16 Glaxosmithkline Biolog Sa Immunogenic composition
CN102596240B (zh) 2009-08-27 2015-02-04 诺华股份有限公司 包括脑膜炎球菌fHBP序列的杂交多肽
US20110110980A1 (en) 2009-09-02 2011-05-12 Wyeth Llc Heterlogous prime-boost immunization regimen
US20120237536A1 (en) 2009-09-10 2012-09-20 Novartis Combination vaccines against respiratory tract diseases
GB0917002D0 (en) 2009-09-28 2009-11-11 Novartis Vaccines Inst For Global Health Srl Improved shigella blebs
GB0917003D0 (en) 2009-09-28 2009-11-11 Novartis Vaccines Inst For Global Health Srl Purification of bacterial vesicles
BR112012009014B8 (pt) 2009-09-30 2022-10-04 Novartis Ag Processo para preparar conjugado de polissacarídeo capsular de s. aureus tipo 5 ou tipo 8 e molécula de transporte crm197, conjugado e composição imunogênica
CN102724988B (zh) 2009-09-30 2014-09-10 诺华股份有限公司 脑膜炎球菌fHBP多肽的表达
BR112012009309B1 (pt) 2009-10-19 2021-10-05 Intervet International B.V Vacina combinada, uso de células de microrganismos,método para a preparação de uma vacina combinada, e, kit de partes
GB0918392D0 (en) 2009-10-20 2009-12-02 Novartis Ag Diagnostic and therapeutic methods
CN102711816A (zh) 2009-10-22 2012-10-03 莱比锡大学 患有牛新生儿全血细胞减少症的小牛中的圆环病毒的检测
CA2779816A1 (fr) 2009-10-27 2011-05-05 Novartis Ag Polypeptides fhbp meningococciques modifies
GB0919690D0 (en) 2009-11-10 2009-12-23 Guy S And St Thomas S Nhs Foun compositions for immunising against staphylococcus aureus
GB201003333D0 (en) 2010-02-26 2010-04-14 Novartis Ag Immunogenic proteins and compositions
MX2012011189A (es) 2010-03-26 2013-02-07 Glaxosmithkline Biolog Sa Vacuna contra el virus e inmunodeficiencia humana.
GB201005625D0 (en) 2010-04-01 2010-05-19 Novartis Ag Immunogenic proteins and compositions
EP2558069A1 (fr) 2010-04-13 2013-02-20 Novartis AG Compositions de benzonapthyridine et leurs utilisations
CA2796178C (fr) 2010-04-21 2021-02-16 Pharmaq As Sequences d'acide nucleique du virus du syndrome de cardiomyopathie chez les poissons et son utilisation
AU2011252844B2 (en) 2010-05-14 2014-07-03 Baxalta GmbH Chimeric OspA genes, proteins, and methods of use thereof
KR20130121699A (ko) 2010-05-28 2013-11-06 테트리스 온라인, 인코포레이티드 상호작용 혼성 비동기 컴퓨터 게임 기반구조
US9238796B2 (en) 2010-06-04 2016-01-19 Toagosei Co. Ltd. Cell growth-promoting peptide and use thereof
GB201009861D0 (en) 2010-06-11 2010-07-21 Novartis Ag OMV vaccines
SG186783A1 (en) * 2010-06-24 2013-02-28 Genentech Inc Compositions and methods containing alkylgycosides for stabilizing protein- containing formulations
US9192661B2 (en) 2010-07-06 2015-11-24 Novartis Ag Delivery of self-replicating RNA using biodegradable polymer particles
WO2012010290A1 (fr) 2010-07-21 2012-01-26 Athera Biotechnologies Ab Méthodes et compositions de diagnostic et de traitement d'une maladie métabolique
WO2012010291A1 (fr) 2010-07-21 2012-01-26 Athera Biotechnologies Ab Méthodes et compositions de diagnostic et de traitement d'une maladie métabolique
EP2595653B1 (fr) 2010-07-23 2017-06-28 Novavax AB Vaccin antigrippal
US8628947B2 (en) 2010-08-30 2014-01-14 Intervet Inc. Potomac horse fever isolates
GB201101665D0 (en) 2011-01-31 2011-03-16 Novartis Ag Immunogenic compositions
JP2014501225A (ja) 2010-09-27 2014-01-20 グラクソスミスクライン バイオロジカルズ ソシエテ アノニム ワクチン
GB201017519D0 (en) 2010-10-15 2010-12-01 Novartis Vaccines Inst For Global Health S R L Vaccines
WO2012059593A1 (fr) 2010-11-05 2012-05-10 Institut National De La Sante Et De La Recherche Medicale (Inserm) Vaccins pour la prévention d'infections à méningocoque
WO2012066481A1 (fr) 2010-11-15 2012-05-24 Pharmaq As Nouvel agent étiologique
WO2012072769A1 (fr) 2010-12-01 2012-06-07 Novartis Ag Epitopes rrgb de pneumocoque et combinaisons de variantes
AU2011340477A1 (en) 2010-12-08 2013-06-20 Neovacs Strongly inactivated and still highly immunogenic vaccine and process of manufacturing thereof
EP2462950A1 (fr) 2010-12-08 2012-06-13 Neovacs Vaccin fortement inactivé mais immunogène hautement stable et son procédé de fabrication
GB201022007D0 (en) 2010-12-24 2011-02-02 Imp Innovations Ltd DNA-sensor
CA2860331A1 (fr) 2010-12-24 2012-06-28 Novartis Ag Composes
CA2822115C (fr) 2010-12-29 2022-05-24 Intervet International B.V. Proteine e2 d'un arbovirus a des salmonides
RU2599544C2 (ru) 2010-12-29 2016-10-10 Интервет Интернэшнл Б.В. Вакцинный антиген бабезиоза собак
CN103298836B (zh) * 2011-01-07 2017-03-08 东亚合成株式会社 用于获得抗疏水性肽抗体的抗原的制备方法
WO2012103361A1 (fr) 2011-01-26 2012-08-02 Novartis Ag Régime d'immunisation contre le vrs
WO2012131099A1 (fr) 2011-03-31 2012-10-04 Institut National De La Sante Et De La Recherche Medicale (Inserm) Utilisation de bactériome sanguin ou tissulaire pour la prédiction, le diagnostic et la prévention de maladies métaboliques et de leurs complications cardiovasculaires
WO2012136739A1 (fr) 2011-04-07 2012-10-11 Neovacs Méthode de traitement d'états liés à l'ifnalpha
EP2508197A1 (fr) 2011-04-07 2012-10-10 Neovacs Procédés de traitement de conditions associées à IFN alpha
CA2835644C (fr) 2011-05-13 2021-06-15 Novartis Ag Antigenes de pre-fusion f du vrs
EP2707025B8 (fr) 2011-05-13 2017-08-23 Zoetis Services LLC Compositions immunogènes contre la glycoprotéine g des virus hendra et nipah
EP2729165B1 (fr) 2011-07-06 2017-11-08 GlaxoSmithKline Biologicals SA Compositions de combinaisons immunogènes et utilisations de celles-ci
CA2841047A1 (fr) 2011-07-06 2013-01-10 Novartis Ag Compositions immunogenes et leurs utilisations
EP2729178A1 (fr) 2011-07-08 2014-05-14 Novartis AG Procédé de ligature de la tyrosine
AR087811A1 (es) 2011-09-08 2014-04-16 Umc Utrecht Holding Bv Vacuna contra el staphylococcus aureus
US9358284B2 (en) 2011-09-14 2016-06-07 Glaxosmithkline Biologicals Sa Methods for making saccharide-protein glycoconjugates
DK2750683T4 (da) 2011-10-03 2021-04-12 Croda Int Plc Nanopartikler, fremgangsmåde til fremstilling og anvendelse deraf som bærer for amfipatiske eller hydrofobe molekyler inden for medicin, herunder cancerbehandling, og i fødevarerelaterede forbindelser
RU2636350C2 (ru) 2011-11-07 2017-11-22 Новартис Аг МОЛЕКУЛА, СОДЕРЖАЩАЯ SPR0096 и SPR2021
MX354902B (es) 2011-11-23 2018-03-23 Bioven 3 Ltd Proteínas recombinantes y sus usos terapéuticos.
ES3018133T3 (en) 2011-11-30 2025-05-14 Univ Emory Jak inhibitors for use in the prevention or treatment of a viral disease caused by a coronaviridae
GB201200259D0 (en) 2012-01-09 2012-02-22 Ohlin Per M Novel therapies
WO2013108272A2 (fr) 2012-01-20 2013-07-25 International Centre For Genetic Engineering And Biotechnology Vaccin antipaludique ciblant le stade sanguin
ES2729967T3 (es) 2012-02-07 2019-11-07 Infectious Disease Res Inst Formulaciones de adyuvante mejoradas que comprenden agonistas de TLR4 y métodos para usar las mismas
HRP20181102T1 (hr) 2012-05-16 2018-09-07 Immune Design Corp Cjepiva za hsv-2
RU2014151567A (ru) 2012-05-22 2016-07-10 Новартис Аг Конъюгат менингококка серогруппы х
WO2013180011A1 (fr) 2012-05-28 2013-12-05 東亞合成株式会社 Peptide antibactérien et son utilisation
US20150140068A1 (en) 2012-07-06 2015-05-21 Novartis Ag Immunogenic compositions and uses thereof
AU2013293448A1 (en) 2012-07-27 2015-02-05 Baxalta GmbH Compositions comprising chimeric OspA molecules and methods of use thereof
US20140037680A1 (en) 2012-08-06 2014-02-06 Glaxosmithkline Biologicals, S.A. Novel method
AU2013301312A1 (en) 2012-08-06 2015-03-19 Glaxosmithkline Biologicals S.A. Method for eliciting in infants an immune response against RSV and B. pertussis
WO2014043189A1 (fr) 2012-09-14 2014-03-20 The Regents Of The University Of Colorado, A Body Corporate Virus de l'herpès déficients pour la réplication conditionnelle et leur utilisation dans des vaccins
JP6283674B2 (ja) 2012-09-18 2018-02-21 グラクソスミスクライン バイオロジカルズ ソシエテ アノニム 外膜小胞
RU2015106791A (ru) 2012-10-03 2016-11-20 Глэксосмитиклайн Байолоджикалз Са Иммуногенные композиции
JP6311935B2 (ja) 2012-10-18 2018-04-18 東亞合成株式会社 ２型ｔｎｆ受容体の発現を抑制する合成ペプチド及びその利用
CN111249455A (zh) 2012-11-30 2020-06-09 葛兰素史密丝克莱恩生物有限公司 假单胞菌抗原和抗原组合
EP2970398B1 (fr) 2013-03-13 2024-05-08 The United States of America, as Represented by The Secretary, Department of Health and Human Services Protéines f de rsv pré-fusion et leur utilisation
EP2970409A2 (fr) 2013-03-15 2016-01-20 Bioven 3 Limited Protéines de synthèse à auto-assemblage
BE1022174B1 (fr) 2013-03-15 2016-02-24 Glaxosmithkline Biologicals S.A. Vaccin
CN105209067A (zh) 2013-03-26 2015-12-30 皮尔布赖特研究所 稳定的fmdv衣壳
AR095962A1 (es) 2013-04-01 2015-11-25 Moreinx Ab Nanopartículas, compuestas de esterol y saponina de quillaja saponaria molina, proceso para preparación y uso de las mismas como portadores para moléculas anfipáticas o hidrófobas en el campo de la medicina incluyendo tratamiento de cáncer y compuestos relacionados con alimentos
MX370573B (es) 2013-04-18 2019-12-17 Immune Design Corp Monoterapia con glucopiranosil lipido a para usarse en el tratamiento del cancer.
US9463198B2 (en) 2013-06-04 2016-10-11 Infectious Disease Research Institute Compositions and methods for reducing or preventing metastasis
MX2016001695A (es) 2013-08-05 2016-05-02 Glaxosmithkline Biolog Sa Composiciones inmunogenas de combinacion.
EP3613430A2 (fr) 2013-10-11 2020-02-26 Servizo Galego De Saúde (Sergas) Vaccins vivants atténués
EP2870974A1 (fr) 2013-11-08 2015-05-13 Novartis AG Vaccins conjugués de salmonelle
MX2016007870A (es) 2013-12-16 2016-10-07 Zoetis Services Llc Composiciones inmunogenas de glucoproteina g de los virus hendra y nipah.
IL310015B2 (en) 2013-12-31 2026-02-01 Access To Advanced Health Inst Single vial formulation
CN106103469B (zh) 2014-03-26 2020-11-27 葛兰素史密丝克莱恩生物有限公司 突变型葡萄球菌抗原
JP7025119B2 (ja) 2014-04-24 2022-02-24 ロード アイランド ホスピタル アスパラギン酸－β－ヒドロキシラーゼは腫瘍においてエピトープ特異的Ｔ細胞応答を誘導する
MX384992B (es) 2014-06-13 2025-03-14 Glaxosmithkline Biologicals Sa Combinaciones inmunógenas.
EP3172324A4 (fr) 2014-07-18 2018-04-25 Oregon Health & Science University Oligoribonucléotides 5'-triphosphate
US10759836B2 (en) 2014-07-18 2020-09-01 University Of Washington Cancer vaccine compositions and methods of use thereof
CN104250640A (zh) 2014-08-22 2014-12-31 普莱柯生物工程股份有限公司 猪伪狂犬病病毒基因缺失株、疫苗组合物及其制备方法和应用
BR112017003462B1 (pt) 2014-09-03 2023-02-14 Intervet International B.V. Coronavírus bovino atenuado e vacina
EP3200820B1 (fr) 2014-10-03 2023-07-05 Intervet International B.V. Vaccin à large spectre contre un réovirus aviaire
EP3207055A1 (fr) 2014-10-15 2017-08-23 Xenothera Composition présentant une immunogénicité réduite
AU2015384786B2 (en) 2015-03-03 2020-08-27 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Display platform from bacterial spore coat proteins
CN111560355A (zh) 2015-03-20 2020-08-21 普莱柯生物工程股份有限公司 一种猪伪狂犬病病毒致弱方法、及其致弱的病毒株、疫苗组合物和应用
US10954492B2 (en) 2015-06-10 2021-03-23 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Processes for production and purification of nucleic acid-containing compositions
CA2996007A1 (fr) 2015-09-03 2017-03-09 Novavax, Inc. Compositions vaccinales ayant une stabilite et une immunogenicite ameliorees
CN105770887A (zh) * 2016-03-04 2016-07-20 邓招红 一种用于hbv疫苗的佐剂及其制备方法
GB2551984B (en) 2016-06-30 2019-01-16 Pharmaq As Fish virus
EP3500292B1 (fr) 2016-08-17 2024-10-16 Pharmaq AS Vaccin contre poux du poisson
GB201614799D0 (en) 2016-09-01 2016-10-19 Glaxosmithkline Biologicals Sa Compositions
US11084850B2 (en) 2016-12-16 2021-08-10 The Pirbright Institute Recombinant prefusion RSV F proteins and uses thereof
WO2018193063A2 (fr) 2017-04-19 2018-10-25 Institute For Research In Biomedicine Nouveaux vaccins contre le paludisme et anticorps se liant aux sporozoïtes de plasmodium
JP7751357B2 (ja) 2017-07-18 2025-10-08 イン３バイオ・リミテッド 合成タンパク質およびその治療学的用途
JP7317796B2 (ja) 2017-07-24 2023-07-31 ノババックス，インコーポレイテッド 呼吸器疾患を治療するための方法および組成物
WO2019051149A1 (fr) 2017-09-08 2019-03-14 Infectious Disease Research Institute Formulations liposomales comprenant de la saponine et procédés d'utilisation
CN120227451A (zh) 2018-03-19 2025-07-01 诺瓦瓦克斯股份有限公司 多价流感纳米颗粒疫苗
EP3581201A1 (fr) 2018-06-15 2019-12-18 GlaxoSmithKline Biologicals S.A. Escherichia coli o157:h7 polypeptides et leurs utilisations
EP3840770A1 (fr) 2018-08-23 2021-06-30 GlaxoSmithKline Biologicals SA Protéines et compositions immunogènes
WO2020097923A1 (fr) 2018-11-16 2020-05-22 The University Of Hong Kong Compositions de virus de la grippe b vivant atténué, leurs procédés de fabrication et d'utilisation
CA3141577A1 (fr) 2019-05-25 2020-12-03 Infectious Disease Research Institute Composition et procede de sechage par atomisation d'une emulsion de vaccin et d'adjuvant
CN114269792B (zh) 2019-06-25 2025-08-08 因斯瑞拜奥有限公司 稳定的嵌合合成蛋白及其治疗用途
WO2021097347A1 (fr) 2019-11-15 2021-05-20 Infectious Disease Research Institute Agoniste de rig-i et formulation d'adjuvant pour le traitement de tumeurs
US10953089B1 (en) 2020-01-27 2021-03-23 Novavax, Inc. Coronavirus vaccine formulations
EP3922255A1 (fr) 2020-06-10 2021-12-15 Prokarium Limited Thérapie du cancer
JP2023553854A (ja) 2020-12-02 2023-12-26 グラクソスミスクライン バイオロジカルズ ソシエテ アノニム ドナー鎖補完性ｆｉｍｈ
WO2022136505A1 (fr) 2020-12-23 2022-06-30 Xenothera Composition d'anticorps polyclonal de porc destinée à être utilisée pour traiter et/ou prévenir une libération de cytokine pro-inflammatoire macrophage dépendante d'un anticorps dans une immunothérapie anti-infectieuse passive
EP4124342A1 (fr) 2021-07-28 2023-02-01 Prokarium Limited Thérapie du cancer avec bacteries vivantes attenuees
WO2023079528A1 (fr) 2021-11-05 2023-05-11 King Abdullah University Of Science And Technology Compositions appropriées pour une utilisation dans un procédé pour déclencher une immunité protectrice croisée contre des coronavirus
CN118510790A (zh) 2021-12-13 2024-08-16 美国政府(由卫生和人类服务部的部长所代表) 噬菌体λ-疫苗系统
GB2622559A (en) 2022-05-10 2024-03-27 Johan Frostegaard Compositions, methods and uses
EP4525989A1 (fr) 2022-05-16 2025-03-26 Zoetis Services LLC Vaccins contre moritella viscosa
GB202209588D0 (en) 2022-06-29 2022-08-10 Plant Bioscience Ltd Methods and compositions
GB202215134D0 (en) 2022-10-13 2022-11-30 Prokarium Ltd Composition
GB202215576D0 (en) 2022-10-21 2022-12-07 Prokarium Ltd Circuit
EP4633671A1 (fr) 2022-12-14 2025-10-22 Yale University Compositions et leurs procédés d'utilisation pour le traitement de cancers entraînés par un virus
US20250085282A1 (en) 2023-09-11 2025-03-13 Novavax, Inc. Method for detecting anti-sars-cov-2 spike (s) immunoglobulins
AU2024353556A1 (en) 2023-09-28 2026-04-02 Prokarium Limited Interleukin 15 variant
WO2025068413A1 (fr) 2023-09-28 2025-04-03 Prokarium Limited Variants d'interleukine 18
US20250144200A1 (en) 2023-11-06 2025-05-08 Novavax, Inc. Intranasal immunogenic compositions
WO2025109155A1 (fr) 2023-11-24 2025-05-30 Prokarium Limited Variant d'interleukine
WO2025224251A1 (fr) 2024-04-24 2025-10-30 Prokarium Limited Micro-organismes modifiés
GB202405780D0 (en) 2024-04-24 2024-06-05 Prokarium Ltd Vacuole escape
WO2025242657A1 (fr) 2024-05-21 2025-11-27 Shape Biopharmaceuticals Ag Blocs et agrégats de construction de lipopeptides
WO2025264964A1 (fr) 2024-06-20 2025-12-26 Zoetis Services Llc Vaccins contre tenacibaculum finnmarkense
WO2026022584A1 (fr) 2024-07-22 2026-01-29 Glaxosmithkline Biologicals Sa Méthodes de retardement de la démence

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1083815A (en) * 1963-10-01 1967-09-20 Wellcome Found Vaccine adjuvants
US4064232A (en) * 1974-01-14 1977-12-20 Sandoz Ltd. Process for isolating the immunogenic components of influenza viruses
GB1502774A (en) * 1974-06-25 1978-03-01 Nat Res Dev Immunological preparations
US4117113A (en) * 1974-06-25 1978-09-26 National Research Development Corporation Immunological preparations
US4196191A (en) * 1975-09-29 1980-04-01 Burroughs Wellcome Co. Biological preparations
US4148876A (en) * 1975-09-29 1979-04-10 Burroughs Wellcome Co. Biological preparations
US4201767A (en) * 1978-11-08 1980-05-06 Merck & Co., Inc. Viral liposome particle
US4235877A (en) * 1979-06-27 1980-11-25 Merck & Co., Inc. Liposome particle containing viral or bacterial antigenic subunit
US4261975A (en) * 1979-09-19 1981-04-14 Merck & Co., Inc. Viral liposome particle
US4251509A (en) * 1980-01-31 1981-02-17 Wisconsin Alumni Research Foundation Dry particulate vaccine for oral administration
DE3014189A1 (de) * 1980-04-14 1981-10-15 Europäisches Laboratorium für Molekularbiologie (EMBL), 6900 Heidelberg Verfahren zur herstellung eines immunogenen membranproteinaggregats von influenza-, parainfluenza- und rhabdo-viren
DE3173713D1 (en) * 1980-09-05 1986-03-20 Frappier Armand Inst Formation of an immunosome exclusively made of viral antigens reconstituted on an artificial membrane
EP0056249B1 (fr) * 1981-01-09 1985-06-26 New York Blood Center, Inc. Composition synthétique d'antigènes et leur procédé de préparation
GB2093039B (en) * 1981-01-29 1984-06-06 Nat Res Dev Improvements relating to hepatitis b vaccine
EP0058021A3 (fr) * 1981-02-06 1982-10-27 Beecham Group Plc Compositions pharmaceutiques
SE8205892D0 (sv) * 1982-10-18 1982-10-18 Bror Morein Immunogent membranproteinkomplex, sett for framstellning och anvendning derav som immunstimulerande medel och sasom vaccin

Also Published As

Publication number Publication date
AR243080A1 (es) 1993-07-30
NZ205925A (en) 1987-10-30
NO163668B (no) 1990-03-26
ES8503951A1 (es) 1985-04-01
AU558258B2 (en) 1987-01-22
SE8205892D0 (sv) 1982-10-18
NO163668C (no) 1990-07-04
CA1243954A (fr) 1988-11-01
MX7563E (es) 1989-10-17
ES526524A0 (es) 1985-04-01
ATE61228T1 (de) 1991-03-15
EP0109942A2 (fr) 1984-05-30
PT77515B (en) 1986-04-16
DK162057C (da) 1992-02-10
DE109942T1 (de) 1984-12-06
US4744983A (en) 1988-05-17
FI833748A0 (fi) 1983-10-14
FI80600C (fi) 1990-07-10
DK478383A (da) 1984-04-19
PT77515A (en) 1983-11-01
DK162057B (da) 1991-09-09
JPH07112983B2 (ja) 1995-12-06
FI833748A7 (fi) 1984-04-19
JPS59186921A (ja) 1984-10-23
FI80600B (fi) 1990-03-30
EP0109942B1 (fr) 1991-03-06
AU2010383A (en) 1984-05-03
EP0109942A3 (en) 1985-08-14
US4578269A (en) 1986-03-25
DK478383D0 (da) 1983-10-17
IE57025B1 (en) 1992-03-25
DE3382190D1 (de) 1991-04-11
IE832394L (en) 1984-04-18
NO833769L (no) 1984-04-24

Similar Documents

Publication Publication Date Title
ZA837603B (en) Immunogenic protein or peptide complex,method of producing said complex and the use thereof as an immune stimulant and as a vaccine
GB2102810B (en) Human interferon-related peptides antigens antibodies and process for preparing the same
IL68749A (en) Modified antigens,their preparation and vaccines containing them
PT86318A (en) Process for the preparation of immunogenic proteins
GB2303855B (en) Helicobacter pylori antigenic protein preparation and immunoassays
GR861242B (en) Method for preparing a compound constituted of a s. mutans adhesive wall which has a protein nature and of a s. mutans polysaccharide and its use as anti-caries vaccine
IL91500A0 (en) Protein of paramyxovirus,method for the production thereof and vaccine containing the same
IL59880A (en) Human le form interferon proteins,method of producing same and formulations comprising them
NZ230773A (en) Nematode antigenic peptides and vaccines
NZ224046A (en) Hiv antigenic peptide fragments and their use
IL82235A (en) Immunogen complexes, their preparation and vaccines comprising them
AU7237391A (en) Carrier-bound recombinant protein, process for producing it and its use as an immunogen and vaccine
NZ233085A (en) Eimeria tenella 100kd immunogenic peptide, vectors, antibodies and vaccines
FI830557A7 (fi) Ihmisen homogeeninen immuuni-interferoni ja menetelmä sen valmistamiseksi.
AU1631188A (en) Newcastle disease virus vaccine and method for the application thereof
ZA885774B (en) Vaccines in which the characteristic epitope is incorporated in a protein of a picornavirus,in particular of poliovirus
EP0265457A4 (fr) Vaccin et implant.
NZ221227A (en) Hiv envelope proteins, antigenic fragments vaccines; and diagnostic methods
IL71953A (en) Malaria associated antigen,process for preparation thereof and vaccine comprising it
GR80009B (en) Novel peptides with immune stimulated action method for the preparation and use thereof
DE3666666D1 (en) Early-summer meningo-encephalitis virus (fsme-virus) vaccine, and method of producing the same
IL81920A (en) Vaccines comprising an antigen and interferon-ypsilon and their preparation
NZ223624A (en) Peptide immunogen from streptococcus mutans, vaccines and antibodies
ZA83114B (en) Bluetongue virus vaccine,method of producing same,and method of immunizing ruminants therewith
ZA881081B (en) Virus antigen,method for its preparation and its use for diagnostic and therapeutic purposes(vaccines)