ZA887862B - Method of purifying protein - Google Patents

Method of purifying protein

Info

Publication number: ZA887862B
Authority: ZA; South Africa
Prior art keywords: disclosed; purifying protein; technique; impurities; csf
Prior art date: 1987-10-23

Application number

ZA887862A

Other languages

English (en)

Inventor

David Naveh

Naveh David

John Chu-Tay Tang

Chu-Tay Tang John

Original Assignee

Schering Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-10-23

Filing date

1988-10-20

Publication date

1989-06-28

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22340970&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ZA887862(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1988-10-20 Application filed by Schering Corp filed Critical Schering Corp

1989-06-28 Publication of ZA887862B publication Critical patent/ZA887862B/xx

Links

238000000034 method Methods 0.000 title abstract 3
102000004169 proteins and genes Human genes 0.000 title abstract 2
108090000623 proteins and genes Proteins 0.000 title abstract 2
239000012535 impurity Substances 0.000 abstract 2
NWUYHJFMYQTDRP-UHFFFAOYSA-N 1,2-bis(ethenyl)benzene;1-ethenyl-2-ethylbenzene;styrene Chemical compound C=CC1=CC=CC=C1.CCC1=CC=CC=C1C=C.C=CC1=CC=CC=C1C=C NWUYHJFMYQTDRP-UHFFFAOYSA-N 0.000 abstract 1
235000019750 Crude protein Nutrition 0.000 abstract 1
102000004457 Granulocyte-Macrophage Colony-Stimulating Factor Human genes 0.000 abstract 1
108010017213 Granulocyte-Macrophage Colony-Stimulating Factor Proteins 0.000 abstract 1
239000003729 cation exchange resin Substances 0.000 abstract 1
238000004255 ion exchange chromatography Methods 0.000 abstract 1
238000000746 purification Methods 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/53—Colony-stimulating factor [CSF]
- C07K14/535—Granulocyte CSF; Granulocyte-macrophage CSF
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J39/00—Cation exchange; Use of material as cation exchangers; Treatment of material for improving the cation exchange properties
- B01J39/26—Cation exchangers for chromatographic processes
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
- C07K1/18—Ion-exchange chromatography

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Analytical Chemistry (AREA)
Biochemistry (AREA)
Biophysics (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Medicinal Chemistry (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Immunology (AREA)
Toxicology (AREA)
Zoology (AREA)
Gastroenterology & Hepatology (AREA)
Chemical Kinetics & Catalysis (AREA)
Peptides Or Proteins (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Enzymes And Modification Thereof (AREA)
Treatment Of Liquids With Adsorbents In General (AREA)
Ultra Sonic Daignosis Equipment (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)

ZA887862A 1987-10-23 1988-10-20 Method of purifying protein ZA887862B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US11188687A	1987-10-23	1987-10-23

Publications (1)

Publication Number	Publication Date
ZA887862B true ZA887862B (en)	1989-06-28

Family

ID=22340970

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA887862A ZA887862B (en)	1987-10-23	1988-10-20	Method of purifying protein

Country Status (21)

Country	Link
EP (2)	EP0391934A1 (da)
JP (1)	JPH0788395B2 (da)
KR (1)	KR930008447B1 (da)
CN (1)	CN1031943C (da)
AT (1)	ATE121418T1 (da)
AU (1)	AU626008B2 (da)
DE (1)	DE3853610T3 (da)
DK (1)	DK99690A (da)
ES (1)	ES2070855T5 (da)
FI (1)	FI103974B (da)
HU (1)	HU204537B (da)
IE (1)	IE72219B1 (da)
IL (1)	IL88118A (da)
MY (1)	MY108512A (da)
NO (1)	NO303451B1 (da)
NZ (1)	NZ226651A (da)
OA (1)	OA09787A (da)
PT (1)	PT88813B (da)
TN (1)	TNSN88111A1 (da)
WO (1)	WO1989003840A1 (da)
ZA (1)	ZA887862B (da)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FI900178A0 (fi) *	1988-05-13	1990-01-12	Amgen Inc	Kompositioner och foerfarande foer behandling eller foerhindrande av infektioner hos djur.
US7217689B1 (en)	1989-10-13	2007-05-15	Amgen Inc.	Glycosylation analogs of erythropoietin
US5110913A (en) *	1990-05-25	1992-05-05	Miles Inc.	Antibody purification method
US5463029A (en) *	1992-11-23	1995-10-31	Immunex Corporation	Purification of fusion proteins comprising GM-CSF and IL-3
WO1995007703A1 (en) *	1993-09-15	1995-03-23	Alpha Therapeutic Corp.	Alpha1-acid glycoprotein purification process and product
US5808011A (en) *	1996-07-01	1998-09-15	Biopure Corporation	Method for chromatographic removal of prions
US7304150B1 (en)	1998-10-23	2007-12-04	Amgen Inc.	Methods and compositions for the prevention and treatment of anemia
CA2369451C (en)	1999-04-08	2009-09-22	Genentech, Inc.	Composition based on oppositely-charged polypeptides
ES2626268T3 (es)	2002-09-11	2017-07-24	Chugai Seiyaku Kabushiki Kaisha	Método de purificación de proteínas
DE10360841A1 (de) *	2003-12-20	2005-07-14	Henkel Kgaa	Helle, stabile, staub- und geruchsarme Enzymgranulate
DK1869065T3 (da) *	2005-03-11	2020-06-08	Wyeth Llc	Fremgangsmåde til kromatografi med svag opdeling
SE529259C2 (sv) *	2005-08-31	2007-06-12	Ge Healthcare Bio Sciences Ab	Tillverkning av kromarografimatriser, en kromarografimatris, en vätskekromatografikolonn, prcess för att isolera målföreningar och användning av en kromarografimatris för vätskekromatografi
NZ577195A (en) *	2006-11-10	2011-12-22	Murray Goulburn Coop Co Ltd	Process for the preparation of angiogenin using a cation exchange resin
CN101556261B (zh) *	2009-05-25	2012-01-11	北京理工大学	微管内等电聚焦和剪断吹出培养测定微生物等电点的方法
CN101556260B (zh) *	2009-05-25	2012-01-11	北京理工大学	固定化pH梯度毛细管等电聚焦测定微生物等电点的方法
WO2013075740A1 (en) *	2011-11-23	2013-05-30	Sanofi	Antibody purification method
US10364268B2 (en) *	2011-12-22	2019-07-30	Genentech, Inc.	Ion exchange membrane chromatography
TWI631132B (zh)	2013-05-06	2018-08-01	賽諾菲公司	用於純化抗體之連續多步驟方法
EP3546475A1 (en)	2018-03-27	2019-10-02	Sanofi	Full flow-through process for purifying recombinant proteins

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4658018A (en) *	1984-03-13	1987-04-14	Immunex Corporation	Process for producing homogeneous colony stimulating factor
IL76360A0 (en) *	1984-09-26	1986-01-31	Takeda Chemical Industries Ltd	Mutual separation of proteins
ZA872781B (en) *	1986-05-19	1987-10-05	Immunology Ventures	B-cell stimulating factor

1988
- 1988-10-19 AU AU26247/88A patent/AU626008B2/en not_active Ceased
- 1988-10-19 DE DE3853610T patent/DE3853610T3/de not_active Expired - Fee Related
- 1988-10-19 AT AT88309824T patent/ATE121418T1/de not_active IP Right Cessation
- 1988-10-19 HU HU886264A patent/HU204537B/hu not_active IP Right Cessation
- 1988-10-19 ES ES88309824T patent/ES2070855T5/es not_active Expired - Lifetime
- 1988-10-19 EP EP88909648A patent/EP0391934A1/en active Pending
- 1988-10-19 WO PCT/US1988/003589 patent/WO1989003840A1/en not_active Ceased
- 1988-10-19 EP EP88309824A patent/EP0313343B2/en not_active Expired - Lifetime
- 1988-10-19 KR KR1019890701131A patent/KR930008447B1/ko not_active Expired - Fee Related
- 1988-10-19 JP JP63508950A patent/JPH0788395B2/ja not_active Expired - Lifetime
- 1988-10-20 PT PT88813A patent/PT88813B/pt not_active IP Right Cessation
- 1988-10-20 ZA ZA887862A patent/ZA887862B/xx unknown
- 1988-10-20 TN TNTNSN88111A patent/TNSN88111A1/fr unknown
- 1988-10-20 NZ NZ226651A patent/NZ226651A/xx unknown
- 1988-10-20 MY MYPI88001190A patent/MY108512A/en unknown
- 1988-10-20 IE IE316888A patent/IE72219B1/en not_active IP Right Cessation
- 1988-10-21 CN CN88107266A patent/CN1031943C/zh not_active Expired - Fee Related
- 1988-10-21 IL IL88118A patent/IL88118A/xx not_active IP Right Cessation
1990
- 1990-04-17 OA OA59777A patent/OA09787A/en unknown
- 1990-04-20 NO NO901769A patent/NO303451B1/no not_active IP Right Cessation
- 1990-04-23 DK DK099690A patent/DK99690A/da unknown
- 1990-04-23 FI FI902017A patent/FI103974B/fi not_active IP Right Cessation

Also Published As

Publication number	Publication date
DE3853610D1 (de)	1995-05-24
DK99690D0 (da)	1990-04-23
NO303451B1 (no)	1998-07-13
IL88118A (en)	1993-06-10
CN1031943C (zh)	1996-06-05
IL88118A0 (en)	1989-06-30
NZ226651A (en)	1990-09-26
ES2070855T5 (es)	2004-03-01
CN1032661A (zh)	1989-05-03
KR930008447B1 (ko)	1993-09-04
FI103974B1 (fi)	1999-10-29
NO901769D0 (no)	1990-04-20
WO1989003840A1 (en)	1989-05-05
AU2624788A (en)	1989-05-23
FI902017A0 (fi)	1990-04-23
NO901769L (no)	1990-04-20
KR890701618A (ko)	1989-12-22
JPH03500649A (ja)	1991-02-14
HUT52783A (en)	1990-08-28
AU626008B2 (en)	1992-07-23
TNSN88111A1 (fr)	1990-07-10
DE3853610T3 (de)	2004-05-13
PT88813B (pt)	1993-01-29
EP0391934A1 (en)	1990-10-17
FI103974B (fi)	1999-10-29
MY108512A (en)	1996-10-31
DK99690A (da)	1990-04-23
IE883168L (en)	1989-04-23
JPH0788395B2 (ja)	1995-09-27
IE72219B1 (en)	1997-04-09
EP0313343B2 (en)	2003-07-23
EP0313343A1 (en)	1989-04-26
HU204537B (en)	1992-01-28
ES2070855T3 (es)	1995-06-16
HU886264D0 (en)	1990-07-28
DE3853610T2 (de)	1995-08-31
EP0313343B1 (en)	1995-04-19
ATE121418T1 (de)	1995-05-15
OA09787A (en)	1994-04-15

Publication	Publication Date	Title
IL88118A0 (en)	1989-06-30	Method of purifying protein
PT81754A (en)	1986-01-02	Processes for purifying tumor necrosis factors and for producing recombinant dna molecules coding for tumor necrosis factor-like compounds and tumor necrosis factors
AU4113385A (en)	1985-10-11	Bone protein purification process
AU5024085A (en)	1986-06-12	Improvements in or relating to a process for purifying proteins
FR2603581B1 (fr)	1993-08-13	Procede pour isoler et purifier des aminoacides par chromatographie
MY103892A (en)	1993-10-30	Interleukin-2 of high purity production and use
ES8600690A1 (es)	1985-11-01	Procedimiento de purificar factores antihemofilicos y similares
ZA868274B (en)	1988-07-27	Purification method for proteins
AU7671087A (en)	1988-02-11	Method for purifying and isolating two ionic forms of somatomedin C
AU1239495A (en)	1995-06-01	An electrophoretic method to assess human cerebrospinal fluid
EP0185249A3 (en)	1988-07-27	Process for the purification of crude beta-phenylethyl alcohol
DE69001309D1 (de)	1993-05-19	Verfahren zur herstellung von antihaemophilem faktor (faktor viii), der eine hohe reinheit aufweist.
PT85956A (en)	1987-11-01	Process for protein purification
DE3568298D1 (en)	1989-03-30	Process for hydrolysis of peptide or protein
IL71580A0 (en)	1984-07-31	Process for the purification of microbial protein isolates
YU137384A (en)	1986-08-31	Process for bacterial production of protein