ZA899626B - Method for solubilization and naturation of somatotropin - Google Patents

Method for solubilization and naturation of somatotropin

Info

Publication number: ZA899626B
Authority: ZA; South Africa
Prior art keywords: naturation; somatotropin; solubilization; denaturants; eliminates
Prior art date: 1988-12-16

Application number

ZA899626A

Other languages

English (en)

Inventor

Kevin Michael Mccoy

Michael Mccoy Kevin

Robert A Frost

A Frost Robert

Original Assignee

American Cyanamid Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1988-12-16

Filing date

1989-12-15

Publication date

1990-09-26

1989-12-15 Application filed by American Cyanamid Co filed Critical American Cyanamid Co

1990-09-26 Publication of ZA899626B publication Critical patent/ZA899626B/xx

Links

102000018997 Growth Hormone Human genes 0.000 title abstract 2
108010051696 Growth Hormone Proteins 0.000 title abstract 2
238000000034 method Methods 0.000 title abstract 2
230000007928 solubilization Effects 0.000 title abstract 2
238000005063 solubilization Methods 0.000 title abstract 2
239000012670 alkaline solution Substances 0.000 abstract 1
230000015572 biosynthetic process Effects 0.000 abstract 1
239000003795 chemical substances by application Substances 0.000 abstract 1
239000003398 denaturant Substances 0.000 abstract 1
239000000539 dimer Substances 0.000 abstract 1
238000004153 renaturation Methods 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/61—Growth hormone [GH], i.e. somatotropin

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Endocrinology (AREA)
Zoology (AREA)
Genetics & Genomics (AREA)
Medicinal Chemistry (AREA)
Biochemistry (AREA)
Molecular Biology (AREA)
General Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Wood Science & Technology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Gastroenterology & Hepatology (AREA)
Engineering & Computer Science (AREA)
Toxicology (AREA)
Biophysics (AREA)
Biotechnology (AREA)
Microbiology (AREA)
General Engineering & Computer Science (AREA)
Biomedical Technology (AREA)
Peptides Or Proteins (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Saccharide Compounds (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Enzymes And Modification Thereof (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Medicines Containing Plant Substances (AREA)

ZA899626A 1988-12-16 1989-12-15 Method for solubilization and naturation of somatotropin ZA899626B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US07/285,477 US5064943A (en)	1988-12-16	1988-12-16	Method for solubilization and naturation of somatotropin

Publications (1)

Publication Number	Publication Date
ZA899626B true ZA899626B (en)	1990-09-26

Family

ID=23094405

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA899626A ZA899626B (en)	1988-12-16	1989-12-15	Method for solubilization and naturation of somatotropin

Country Status (18)

Country	Link
US (1)	US5064943A (da)
EP (1)	EP0373325B1 (da)
JP (1)	JPH02222697A (da)
KR (1)	KR0148681B1 (da)
AT (1)	ATE136309T1 (da)
AU (1)	AU628443B2 (da)
CA (1)	CA2005478C (da)
DE (1)	DE68926153T2 (da)
DK (1)	DK174662B1 (da)
ES (1)	ES2087065T3 (da)
FI (1)	FI102179B (da)
GR (1)	GR3019691T3 (da)
HU (1)	HU213572B (da)
IE (1)	IE74848B1 (da)
IL (1)	IL92135A (da)
NZ (1)	NZ231681A (da)
PT (1)	PT92305B (da)
ZA (1)	ZA899626B (da)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5340926A (en) *	1983-03-25	1994-08-23	Celltech, Limited	Process for the recovery of recombinantly produced protein from insoluble aggregate
US5332805A (en) *	1984-02-03	1994-07-26	Celltech Limited	Process for the recovery of recombinantly produced chymosin from insoluble aggregate
US5317324A (en) *	1991-06-20	1994-05-31	Sumitomo Metal Mining Co., Ltd.	Printed antenna
US5151501A (en) *	1991-12-20	1992-09-29	American Cyanamid Company	Method for solubilization and naturation of somatotropins utilizing sulfolane
AU4665193A (en) *	1992-07-02	1994-01-31	Pitman-Moore, Inc.	A process for recovering a recombinant protein, in biologically active form, from a solution containing inactive protein
ZA94169B (en) *	1993-01-26	1994-09-07	Lilly Co Eli	Non-denaturing potency assay for bovine somatotropin
US5567620A (en) *	1993-01-26	1996-10-22	Eli Lilly And Company	Non-denaturing potency assay for somatotropin
EP1095056B1 (en)	1998-07-09	2006-12-27	BaroFold, Inc.	High pressure refolding of protein aggregates and inclusion bodies
EP1149160B1 (en) *	1999-01-25	2006-04-19	Novozymes A/S	Recovery of a protein at high ph
CA2434045A1 (en) *	2000-10-31	2002-08-15	The Regents Of The University Of Colorado, A Body Corporate	Improved protein disaggregation and refolding using high pressure
CA2443365C (en) *	2002-11-19	2010-01-12	F. Hoffmann-La Roche Ag	Methods for the recombinant production of antifusogenic peptides
AR062069A1 (es) *	2006-07-14	2008-10-15	Genentech Inc	Replegado de proteinas recombinantes
CA2663416A1 (en) *	2006-09-15	2008-03-20	Barofold, Inc.	High pressure treatment of proteins for reduced immunogenicity
BR102013026129A2 (pt) *	2013-10-10	2016-05-24	Ouro Fino Participações E Empreendimentos S A	processo para a produção de somatotropina bovina recombinate ativa e produto obtido

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IE55163B1 (en) *	1982-06-07	1990-06-20	Celltech Ltd	A process for the preparation of chymosin
US4511503A (en) *	1982-12-22	1985-04-16	Genentech, Inc.	Purification and activity assurance of precipitated heterologous proteins
EP0122080B1 (en) *	1983-03-25	1989-09-13	Celltech Limited	A process for the production of a protein
CA1267615A (en) *	1984-08-27	1990-04-10	Dan Hadary	Method for recovering purified growth hormones from genetically engineered microorganisms
ES8800957A1 (es) *	1985-02-22	1987-12-01	Monsanto Co	Un metodo para la solubilizacion y renaturalizacion de proteina somatotropina
US4652630A (en) *	1985-02-22	1987-03-24	Monsanto Company	Method of somatotropin naturation
US4677196A (en) *	1985-09-06	1987-06-30	International Minerals & Chemical Corp.	Purification and activation of proteins from insoluble inclusion bodies
AU3439089A (en) *	1988-08-05	1990-03-05	Ralph Akyuz	Skin protection lotion
JP2531272B2 (ja) *	1988-08-11	1996-09-04	日本電気株式会社	フレ―ム同期制御方式

1988
- 1988-12-16 US US07/285,477 patent/US5064943A/en not_active Expired - Lifetime
1989
- 1989-10-19 ES ES89119409T patent/ES2087065T3/es not_active Expired - Lifetime
- 1989-10-19 EP EP89119409A patent/EP0373325B1/en not_active Expired - Lifetime
- 1989-10-19 DE DE68926153T patent/DE68926153T2/de not_active Expired - Fee Related
- 1989-10-19 AT AT89119409T patent/ATE136309T1/de not_active IP Right Cessation
- 1989-10-27 IL IL9213589A patent/IL92135A/en not_active IP Right Cessation
- 1989-11-06 IE IE356189A patent/IE74848B1/en not_active IP Right Cessation
- 1989-11-14 PT PT92305A patent/PT92305B/pt not_active IP Right Cessation
- 1989-12-08 NZ NZ231681A patent/NZ231681A/xx unknown
- 1989-12-14 JP JP1322768A patent/JPH02222697A/ja active Pending
- 1989-12-14 CA CA002005478A patent/CA2005478C/en not_active Expired - Fee Related
- 1989-12-14 AU AU46750/89A patent/AU628443B2/en not_active Expired
- 1989-12-15 FI FI896021A patent/FI102179B/fi not_active IP Right Cessation
- 1989-12-15 KR KR1019890018683A patent/KR0148681B1/ko not_active Expired - Fee Related
- 1989-12-15 DK DK198906390A patent/DK174662B1/da not_active IP Right Cessation
- 1989-12-15 ZA ZA899626A patent/ZA899626B/xx unknown
- 1989-12-15 HU HU896639A patent/HU213572B/hu not_active IP Right Cessation
1996
- 1996-04-22 GR GR950403213T patent/GR3019691T3/el unknown

Also Published As

Publication number	Publication date
CA2005478C (en)	2000-01-04
FI102179B1 (fi)	1998-10-30
FI896021A0 (fi)	1989-12-15
IE74848B1 (en)	1997-08-13
HU213572B (en)	1997-08-28
JPH02222697A (ja)	1990-09-05
DK639089D0 (da)	1989-12-15
AU628443B2 (en)	1992-09-17
EP0373325A3 (en)	1991-06-12
IL92135A (en)	1995-05-26
CA2005478A1 (en)	1990-06-16
EP0373325A2 (en)	1990-06-20
HU896639D0 (en)	1990-02-28
DE68926153T2 (de)	1996-10-24
DK639089A (da)	1990-06-17
EP0373325B1 (en)	1996-04-03
ES2087065T3 (es)	1996-07-16
DK174662B1 (da)	2003-08-18
PT92305B (pt)	1995-07-18
AU4675089A (en)	1990-06-21
PT92305A (pt)	1990-06-29
FI102179B (fi)	1998-10-30
US5064943A (en)	1991-11-12
KR0148681B1 (ko)	1998-08-01
GR3019691T3 (en)	1996-07-31
IE893561L (en)	1990-06-16
ATE136309T1 (de)	1996-04-15
KR900009971A (ko)	1990-07-06
HUT52563A (en)	1990-07-28
DE68926153D1 (de)	1996-05-09
NZ231681A (en)	1993-09-27
IL92135A0 (en)	1990-07-12

Publication	Publication Date	Title
ZA899626B (en)	1990-09-26	Method for solubilization and naturation of somatotropin
EP0515228A3 (da)	1994-05-04
ZA881067B (en)	1988-08-11	Production of proteins in active forms
DK80986A (da)	1986-08-23	Fremgangsmaade til at solubilisere somatotropinproteiner og bringe disse tilbage til naturlig tilstand
AU2284188A (en)	1990-03-29	Improved process for recovering microbially produced interferon-beta
EP0475927A3 (en)	1992-12-09	Method of somatotropin naturation
ZA909745B (en)	1991-10-30	Method for solubilization and naturation of somatotropins utilizing low urea concentration
FR2637775B1 (fr)	1991-01-18	Procede et dispositif de maintien d'une piece de viande au cours de son desossage
FR2637776B1 (fr)	1992-07-10	Dispositif et procede de maintien d'une piece de viande au cours de son desossage
KR960008652B1 (en)	1996-06-28	Method of increasing concentration of endogenous growth hormone of an economic mamals
IL106634A0 (en)	1993-12-08	Method and standard solution for the determination of thyroxine(t4)or triiodothyronine(t3)
JPS61138466U (da)	1986-08-28