ZA90681B - Heterocyclic compounds - Google Patents

Heterocyclic compounds

Info

Publication number: ZA90681B
Authority: ZA; South Africa
Prior art keywords: lower alkyl; chem; alkyl group; hydrogen; mean
Prior art date: 1989-02-11

Application number

ZA90681A

Other languages

English (en)

Inventor

Heimo Olavi Haikala

Olavi Haikala Heimo

Erkki Juhani Honkanen

Juhani Honkanen Erkki

Kari Kalevi Lonnberg

Kalevi Lonnberg Kari

Pentti Tapio Nore

Tapio Nore Pentti

Jarmo Johan Pystynen

Johan Pystynen Jarmo

Anne Maria Luiro

Maria Luiro Anne

Aino Kyllikki Pippuri

Kyllikki Pippuri Aino

Original Assignee

Orion Yhtymae Oy

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-02-11

Filing date

1990-01-30

Publication date

1990-10-31

1990-01-30 Application filed by Orion Yhtymae Oy filed Critical Orion Yhtymae Oy

1990-10-31 Publication of ZA90681B publication Critical patent/ZA90681B/xx

Links

150000002391 heterocyclic compounds Chemical class 0.000 title abstract 2
125000000217 alkyl group Chemical group 0.000 abstract 5
229910052739 hydrogen Inorganic materials 0.000 abstract 4
239000001257 hydrogen Substances 0.000 abstract 4
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 2
125000004093 cyano group Chemical group *C#N 0.000 abstract 2
150000002431 hydrogen Chemical class 0.000 abstract 2
206010007559 Cardiac failure congestive Diseases 0.000 abstract 1
206010019280 Heart failures Diseases 0.000 abstract 1
125000002252 acyl group Chemical group 0.000 abstract 1
125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 1
125000003435 aroyl group Chemical group 0.000 abstract 1
125000003118 aryl group Chemical group 0.000 abstract 1
125000005518 carboxamido group Chemical group 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
229910052736 halogen Inorganic materials 0.000 abstract 1
150000002367 halogens Chemical class 0.000 abstract 1
125000005842 heteroatom Chemical group 0.000 abstract 1
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
125000004029 hydroxymethyl group Chemical group [H]OC([H])([H])* 0.000 abstract 1
125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
229910052760 oxygen Inorganic materials 0.000 abstract 1
125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
125000004076 pyridyl group Chemical group 0.000 abstract 1
229910052717 sulfur Inorganic materials 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
- C07D285/15—Six-membered rings
- C07D285/16—Thiadiazines; Hydrogenated thiadiazines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/04—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having less than three double bonds between ring members or between ring members and non-ring members
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D237/14—Oxygen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/26—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings condensed with carbocyclic rings or ring systems
- C07D237/30—Phthalazines
- C07D237/32—Phthalazines with oxygen atoms directly attached to carbon atoms of the nitrogen-containing ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D253/00—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
- C07D253/02—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 not condensed with other rings
- C07D253/06—1,2,4-Triazines
- C07D253/065—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members
- C07D253/07—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members with hetero atoms, or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D273/00—Heterocyclic compounds containing rings having nitrogen and oxygen atoms as the only ring hetero atoms, not provided for by groups C07D261/00 - C07D271/00
- C07D273/02—Heterocyclic compounds containing rings having nitrogen and oxygen atoms as the only ring hetero atoms, not provided for by groups C07D261/00 - C07D271/00 having two nitrogen atoms and only one oxygen atom
- C07D273/04—Six-membered rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Cardiology (AREA)
General Health & Medical Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Heart & Thoracic Surgery (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Hospice & Palliative Care (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Cephalosporin Compounds (AREA)
Saccharide Compounds (AREA)
Pyridine Compounds (AREA)
Detergent Compositions (AREA)
Compounds Of Unknown Constitution (AREA)

ZA90681A 1989-02-11 1990-01-30 Heterocyclic compounds ZA90681B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB898903130A GB8903130D0 (en)	1989-02-11	1989-02-11	Substituted pyridazinones

Publications (1)

Publication Number	Publication Date
ZA90681B true ZA90681B (en)	1990-10-31

Family

ID=10651554

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA90681A ZA90681B (en)	1989-02-11	1990-01-30	Heterocyclic compounds

Country Status (24)

Country	Link
US (2)	US5019575A (de)
EP (1)	EP0383449B1 (de)
JP (1)	JP3011955B2 (de)
CN (1)	CN1036265C (de)
AT (1)	ATE127456T1 (de)
AU (1)	AU619648B2 (de)
CA (1)	CA2009678C (de)
CZ (1)	CZ286036B6 (de)
DD (1)	DD293112A5 (de)
DE (1)	DE69022078T2 (de)
DK (1)	DK0383449T3 (de)
ES (1)	ES2078939T3 (de)
FI (1)	FI96511C (de)
GB (2)	GB8903130D0 (de)
GR (1)	GR3017510T3 (de)
HU (2)	HU204797B (de)
LT (1)	LT3769B (de)
LU (1)	LU90921I2 (de)
NO (2)	NO178067C (de)
NZ (1)	NZ232257A (de)
PT (1)	PT93111B (de)
RU (3)	RU2048467C1 (de)
SK (1)	SK280411B6 (de)
ZA (1)	ZA90681B (de)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
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GB8824458D0 (en) *	1988-10-19	1988-11-23	Orion Yhtymae Oy	Substituted pyridazinones
IE62890B1 (en) *	1988-12-06	1995-03-08	Hafslund Nycomed Pharma	New piperazinylalkyl-3(2h)-pyridazinones process for the preparation thereof and the use thereof as agents lowering blood pressure
GB8903130D0 (en) *	1989-02-11	1989-03-30	Orion Yhtymae Oy	Substituted pyridazinones
GB2251615B (en) *	1991-01-03	1995-02-08	Orion Yhtymae Oy	(-)-[[4-(1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazinyl)phenyl]hydrazono]pro panedinitrile
GB2266841A (en) *	1992-05-06	1993-11-17	Orion Yhtymae Oy	Compounds for use as anti-ischemic medicaments
DE4239540A1 (de) *	1992-11-25	1994-05-26	Asta Medica Ag	Neue heterocyclische Verbindungen mit antiasthmatischer/antiallergischer, entzündungshemmender, positiv inotroper und blutdrucksenkender Wirkung
TW309520B (de) *	1994-04-26	1997-07-01	Mitsubishi Chem Corp
DE19514568A1 (de)	1995-04-20	1996-10-24	Merck Patent Gmbh	Arylalkyl-pyridazinone
GB9606474D0 (en)	1996-03-27	1996-06-05	Orion Yhytmo Oy	Method for obtaining pure enantiomers of a pyridazinone derivative
GB9626472D0 (en)	1996-12-20	1997-02-05	Aperia Anita C	New use of comt inhibitors
FI973804A7 (fi) *	1997-09-26	1999-03-27	Orion Yhtymae Oy	Levosimendaanin oraalisia koostumuksia
FI980902A7 (fi)	1998-04-23	1999-10-24	Orion Yhtymae Oyj	Levosimendaanin stabiileja koostumuksia
FI105389B (fi) *	1998-04-23	2000-08-15	Orion Yhtymae Oyj	Menetelmä levosimendaaniannon siedettävyyden seuraamiseksi
FI980901A7 (fi) *	1998-04-23	1999-10-24	Orion Yhtymae Oyj	Levosimendaania säädellysti vapauttavia oraalisia koostumuksia
FI104718B (fi) *	1998-06-18	2000-03-31	Orion Yhtymae Oyj	[[4-(2-atsido-3-metyyli-5-oksotetrahydrofuran-2-yyli)fenyyli]hydratsono]propaanidinitriili käytettäväksi referenssiaineena levosimendaanierien analyysissä
FI20000577A0 (fi) *	2000-03-13	2000-03-13	Orion Yhtymae Oy	Pyridatsinyylifenyylihydratsoneja
FI20002525A7 (fi) *	2000-11-17	2002-05-18	Orion Yhtymae Oyj	Tulehduksenvastaisia aineita
WO2002072099A1 (en) *	2001-03-14	2002-09-19	Mitsubishi Pharma Corporation	Therapeutic and/or preventive agent for diabetic ischemic heart disease
EP1612204A4 (de) *	2003-03-31	2007-04-11	Daiichi Seiyaku Co	Hydrazon-derivate
DE102004011512B4 (de)	2004-03-08	2022-01-13	Boehringer Ingelheim Vetmedica Gmbh	Pharmazeutische Zubereitung enthaltend Pimobendan
EP1579862A1 (de)	2004-03-25	2005-09-28	Boehringer Ingelheim Vetmedica Gmbh	Verwendung von PDE III Ihibitoren zur Reduktion der Herzgrösse in an Herzversagen leidenden Säugern
US8980894B2 (en)	2004-03-25	2015-03-17	Boehringer Ingelheim Vetmedica Gmbh	Use of PDE III inhibitors for the treatment of asymptomatic (occult) heart failure
AU2005249498B2 (en) *	2004-05-28	2010-06-24	Orion Corporation	Methods for treating a mammal before, during and after cardiac arrest
WO2007054514A2 (en)	2005-11-14	2007-05-18	Boehringer Ingelheim Vetmedica Gmbh	Use of pde iii inhibitors or calcium sensitizers for the treatment of asymptomatic (occult) heart failure
MX2009000884A (es)	2006-07-25	2009-06-05	Cephalon Inc	Derivados de piridizinona.
EP1920785A1 (de)	2006-11-07	2008-05-14	Boehringer Ingelheim Vetmedica Gmbh	Pimobendan-Cyclodextrin Komplex enthaltendes flüssiges Präparat
FR2917975B1 (fr)	2007-06-26	2009-10-16	Ceva Sante Animale Sa	Compositions et traitement de l'insuffisance cardiaque chez les animaux mammiferes non humains
CA2645772A1 (en) *	2007-12-05	2009-06-05	Tagawa Greenhouse Enterprises, Llc	Collapsible support apparatus and methods
MX2011005444A (es)	2008-11-25	2011-06-09	Boehringer Ingelheim Vetmed	Inhibidores de la fosfodiesterasa tipo iii (pde iii) o agentes sensibilizantes a iones de ca(2+) para el tratamiento de la cardiomiopatia hipertrofica.
EP3167876B1 (de)	2012-03-15	2021-09-08	Boehringer Ingelheim Vetmedica GmbH	Pharmazeutische tablettenformulierung für den veterinärmedizinischen sektor, verfahren zur herstellung und verwendung davon
WO2014113620A2 (en) *	2013-01-18	2014-07-24	Bristol-Myers Squibb Company	Phthalazinones and isoquinolinones as rock inhibitors
DK3021832T3 (da)	2013-07-19	2021-05-25	Boehringer Ingelheim Vetmedica Gmbh	Konserverede etherificerede cyclodextrinderivater indeholdende flydende vandig farmaceutisk sammensætning
ES2593210T3 (es)	2013-12-04	2016-12-07	Boehringer Ingelheim Vetmedica Gmbh	Composiciones farmacéuticas mejoradas de pimobendán
US10537570B2 (en)	2016-04-06	2020-01-21	Boehringer Ingelheim Vetmedica Gmbh	Use of pimobendan for the reduction of heart size and/or the delay of onset of clinical symptoms in patients with asymptomatic heart failure due to mitral valve disease
EP3424908A1 (de)	2017-07-07	2019-01-09	Melody Healthcare Pvt. Ltd.	Verfahren zur herstellung von levosimendan
KR102128509B1 (ko) *	2018-12-19	2020-07-01	한국과학기술연구원	말단 아민기에 아릴 또는 헤테로아릴기가 치환된 신규한 히드라존 유도체 및 이의 용도
CN111548310B (zh) *	2020-05-12	2021-07-02	成都欣捷高新技术开发股份有限公司	一种左西孟旦钠晶型及其制备方法
KR102356644B1 (ko) *	2020-06-19	2022-01-28	한국과학기술연구원	신규한 옥소피리다지닐-페닐-카르보노하이드라조노일 디시아나이드 화합물 및 이의 용도
US11760730B2 (en)	2021-01-11	2023-09-19	Navinta, Llc	Process for the preparation of high purity Levosimendan

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US3432507A (en) *	1963-12-04	1969-03-11	Upjohn Co	Certain diazatricyclododecadienones and their preparation
EP0052442B1 (de) *	1980-11-14	1985-09-11	Imperial Chemical Industries Plc	Heterocyclische Derivate
US4353905A (en) *	1981-09-17	1982-10-12	Warner-Lambert Company	Substituted 4,5-dihydro-6-[4-(1H-imidazol-1-yl)phenyl]-3(2H)-pyridazinones and 6-[4-(1H-imidazol-1-yl)phenyl]-3(2H)-pyridazinones
US4495185A (en) *	1981-11-12	1985-01-22	Imperial Chemical Industries, Plc	1,2,4-Triazin-3(2H) ones
JPS58113180A (ja) *	1981-12-28	1983-07-05	Mitsui Toatsu Chem Inc	ピリダジノン誘導体
US4581356A (en) *	1983-03-22	1986-04-08	Fujisawa Pharmaceutical Co., Ltd.	Triazine derivatives, and pharmaceutical compositions comprising the same
GB8310435D0 (en) *	1983-04-18	1983-05-25	Fujisawa Pharmaceutical Co	Triazine derivatives
JPS59196874A (ja) *	1983-04-22	1984-11-08	Fujisawa Pharmaceut Co Ltd	トリアジン誘導体
US4599332A (en) *	1983-12-07	1986-07-08	Warner-Lambert Company	4,5-dihydro-6-[2-[4-(1H-imidazol-1-yl)phenyl]-ethenyl]-3(2H)-pyridazinones and related compounds
JPS61158969A (ja) *	1984-12-24	1986-07-18	ワーナー‐ランバート・コンパニー	４，５‐ジヒドロ‐４，４‐ジアルキル‐６‐（置換）フエニル‐３（２ｈ）‐ピリダジノン類
US4656170A (en) *	1985-05-28	1987-04-07	Warner-Lambert Company	N-[4-[2-(1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazinyl)ethenyl]phenyl]acetamide and related compounds
AU581324B2 (en) *	1985-07-05	1989-02-16	Smith Kline & French Laboratories Limited	Substituted 6-phenyl-4,5-dihydro pyradazin-3-ones
DE3531658A1 (de)	1985-09-05	1987-03-12	Boehringer Mannheim Gmbh	Heterocyclisch substituierte indole, zwischenprodukte, verfahren zu ihrer herstellung und arzneimittel
GB8603780D0 (en) *	1986-02-15	1986-03-19	Smith Kline French Lab	Chemical compounds
US4898862A (en) *	1986-03-20	1990-02-06	Sankyo Company Limited	1,2,4-triazinone derivatives, their preparation and use
IT1208003B (it) *	1987-01-08	1989-06-01	Isf Spa	Procedimento per preparare derivati alcossi alchiliden, idrazino, piridazinici.
DE3706427A1 (de) *	1987-02-27	1988-09-08	Boehringer Mannheim Gmbh	Neue substituierte 3h-indole, zwischenprodukte, verfahren zu ihrer herstellung sowie arzneimittel
DE3728491A1 (de) *	1987-08-26	1989-03-09	Heumann Pharma Gmbh & Co	Dihydropyridazinon-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
JP2717687B2 (ja) *	1988-02-13	1998-02-18	日本曹達株式会社	ピリダジノン誘導体及びその製造方法
GB8903130D0 (en) *	1989-02-11	1989-03-30	Orion Yhtymae Oy	Substituted pyridazinones

1989
- 1989-02-11 GB GB898903130A patent/GB8903130D0/en active Pending
1990
- 1990-01-24 NO NO900336A patent/NO178067C/no not_active IP Right Cessation
- 1990-01-26 GB GB9001853A patent/GB2228004B/en not_active Expired - Lifetime
- 1990-01-26 NZ NZ232257A patent/NZ232257A/en unknown
- 1990-01-29 ES ES90300875T patent/ES2078939T3/es not_active Expired - Lifetime
- 1990-01-29 DE DE69022078T patent/DE69022078T2/de not_active Expired - Lifetime
- 1990-01-29 AT AT90300875T patent/ATE127456T1/de active
- 1990-01-29 EP EP90300875A patent/EP0383449B1/de not_active Expired - Lifetime
- 1990-01-29 DK DK90300875.3T patent/DK0383449T3/da active
- 1990-01-30 ZA ZA90681A patent/ZA90681B/xx unknown
- 1990-02-06 CZ CS90557A patent/CZ286036B6/cs not_active IP Right Cessation
- 1990-02-06 SK SK557-90A patent/SK280411B6/sk not_active IP Right Cessation
- 1990-02-08 FI FI900613A patent/FI96511C/fi active Protection Beyond IP Right Term
- 1990-02-08 AU AU49296/90A patent/AU619648B2/en not_active Expired
- 1990-02-09 US US07/477,530 patent/US5019575A/en not_active Expired - Lifetime
- 1990-02-09 HU HU90747A patent/HU204797B/hu unknown
- 1990-02-09 PT PT93111A patent/PT93111B/pt not_active IP Right Cessation
- 1990-02-09 JP JP2031339A patent/JP3011955B2/ja not_active Expired - Lifetime
- 1990-02-09 HU HU913501D patent/HU206692B/hu unknown
- 1990-02-09 DD DD90337728A patent/DD293112A5/de not_active IP Right Cessation
- 1990-02-09 RU SU904743235A patent/RU2048467C1/ru active
- 1990-02-09 CA CA002009678A patent/CA2009678C/en not_active Expired - Lifetime
- 1990-02-10 CN CN90100645A patent/CN1036265C/zh not_active Expired - Lifetime
1991
- 1991-03-15 US US07/670,338 patent/US5122524A/en not_active Expired - Lifetime
- 1991-05-05 RU SU914895242A patent/RU1836362C/ru active
1992
- 1992-06-29 RU SU925011896A patent/RU2068844C1/ru active
1993
- 1993-09-28 LT LTIP1233A patent/LT3769B/lt not_active IP Right Cessation
1995
- 1995-09-22 GR GR950402628T patent/GR3017510T3/el unknown
2001
- 2001-11-19 NO NO2001020C patent/NO2001020I1/no unknown
2002
- 2002-05-17 LU LU90921C patent/LU90921I2/en unknown

Also Published As

Publication number	Publication date
JP3011955B2 (ja)	2000-02-21
CZ286036B6 (cs)	1999-12-15
NO2001020I1 (no)	2001-12-03
EP0383449A2 (de)	1990-08-22
DE69022078T2 (de)	1996-02-22
ES2078939T3 (es)	1996-01-01
JPH02288868A (ja)	1990-11-28
US5122524A (en)	1992-06-16
LTIP1233A (en)	1995-04-25
NZ232257A (en)	1991-03-26
HUT53090A (en)	1990-09-28
GB2228004A (en)	1990-08-15
LU90921I2 (en)	2002-07-17
RU2068844C1 (ru)	1996-11-10
CN1036265C (zh)	1997-10-29
CN1044811A (zh)	1990-08-22
NO900336D0 (no)	1990-01-24
ATE127456T1 (de)	1995-09-15
SK55790A3 (en)	2000-02-14
RU1836362C (ru)	1993-08-23
HU913501D0 (en)	1992-02-28
EP0383449B1 (de)	1995-09-06
LT3769B (en)	1996-03-25
DK0383449T3 (da)	1996-01-02
NO178067B (no)	1995-10-09
AU619648B2 (en)	1992-01-30
CA2009678A1 (en)	1990-08-11
FI900613A0 (fi)	1990-02-08
HUT59384A (en)	1992-05-28
FI96511C (fi)	1996-07-10
PT93111A (pt)	1990-08-31
GB8903130D0 (en)	1989-03-30
GB9001853D0 (en)	1990-03-28
DE69022078D1 (de)	1995-10-12
NO178067C (no)	1996-01-17
AU4929690A (en)	1990-08-16
DD293112A5 (de)	1991-08-22
FI96511B (fi)	1996-03-29
EP0383449A3 (de)	1991-07-03
PT93111B (pt)	1996-01-31
HU900747D0 (en)	1990-04-28
GB2228004B (en)	1992-07-15
HU204797B (en)	1992-02-28
GR3017510T3 (en)	1995-12-31
US5019575A (en)	1991-05-28
HU206692B (en)	1992-12-28
RU2048467C1 (ru)	1995-11-20
SK280411B6 (sk)	2000-02-14
CZ55790A3 (cs)	1999-10-13
CA2009678C (en)	1998-08-11
NO900336L (no)	1990-08-13

Publication	Publication Date	Title
GB2228004B (en)	1992-07-15	Heterocyclic compounds
PH22999A (en)	1989-02-24	3-cyano-5-(6-imidazo(1,2-a)pyridyl)-pyridin-2-ols useful as cardiotonics
CA2082574A1 (en)	1993-05-19	3-isoxazolylphenyl compounds, their preparation and their use
ATE143949T1 (de)	1996-10-15	Buten- oder propensäure-derivate
MY106474A (en)	1995-05-30	Guanidine derivatives.
BG101601A (bg)	1998-02-27	Фармацевтични пиперазинови производни
HUT42277A (en)	1987-07-28	Herbicides containing as active subtance derivatives of new 1-aryl-4-nitro-pirasole and process for production of the active substances
EP0449195A3 (en)	1992-05-13	Aminobenzene compounds, their production and use
ATE137759T1 (de)	1996-05-15	S'-adenosyl-methionin-decarboxylase-inhibitoren
FR2529891B1 (de)	1985-01-11
NO954764L (no)	1996-01-25	Psoralen-derivater, deres fremstilling og anvendelse
HUT48201A (en)	1989-05-29	Herbicide comprising anilide derivatives and process for producing such compounds
FI921298A7 (fi)	1992-03-25	Menetelmä lääkeaineena käyttökelpoisen 5-(6-imidatso/1,2-a/pyridyyli)pyridiini-johdannaisen valmistamiseksi
ATE53216T1 (de)	1990-06-15	Phosphono pyridine und ihre 1,4-dihydroderivate.