ZA923239B - Glycosphingolipids and the use thereof. - Google Patents

Glycosphingolipids and the use thereof.

Info

Publication number
ZA923239B
ZA923239B ZA923239A ZA923239A ZA923239B ZA 923239 B ZA923239 B ZA 923239B ZA 923239 A ZA923239 A ZA 923239A ZA 923239 A ZA923239 A ZA 923239A ZA 923239 B ZA923239 B ZA 923239B
Authority
ZA
South Africa
Prior art keywords
sphingoglycolipid
integer
glycosphingolipids
chem
isopropyl
Prior art date
Application number
ZA923239A
Other languages
English (en)
Inventor
Tatsuo Higal
Koji Akimoto
Yasuhiko Koezuka
Teruyuki Sakai
Masahiro Morita
Takenori Natori
Original Assignee
Kirin Brewery
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kirin Brewery filed Critical Kirin Brewery
Publication of ZA923239B publication Critical patent/ZA923239B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • C07H15/10—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical containing unsaturated carbon-to-carbon bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/44—Preparation of O-glycosides, e.g. glucosides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • External Artificial Organs (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
ZA923239A 1991-08-29 1992-05-05 Glycosphingolipids and the use thereof. ZA923239B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP3244384A JPH0559081A (ja) 1991-08-29 1991-08-29 新規スフインゴ糖脂質、その製造法および使用

Publications (1)

Publication Number Publication Date
ZA923239B true ZA923239B (en) 1993-05-05

Family

ID=17117885

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA923239A ZA923239B (en) 1991-08-29 1992-05-05 Glycosphingolipids and the use thereof.

Country Status (18)

Country Link
EP (1) EP0609437B1 (de)
JP (2) JPH0559081A (de)
KR (1) KR100220793B1 (de)
AT (1) ATE181922T1 (de)
AU (1) AU665536B2 (de)
CA (1) CA2116442C (de)
DE (1) DE69229557T2 (de)
DK (1) DK0609437T3 (de)
ES (1) ES2134213T3 (de)
FI (1) FI105189B (de)
GR (1) GR3030723T3 (de)
HU (1) HU223839B1 (de)
NO (1) NO180338C (de)
PT (1) PT100736B (de)
SG (1) SG44031A1 (de)
TW (1) TW197446B (de)
WO (1) WO1993005055A1 (de)
ZA (1) ZA923239B (de)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5936076A (en) * 1991-08-29 1999-08-10 Kirin Beer Kabushiki Kaisha αgalactosylceramide derivatives
TW261533B (de) * 1992-07-16 1995-11-01 Kirin Brewery
KR100281264B1 (ko) * 1992-10-22 2001-02-01 마나배 게이사꾸 신규한 스핀고당 지질 및 그의 사용
JP4020958B2 (ja) * 1993-04-15 2007-12-12 キリンファーマ株式会社 新規スフィンゴ糖脂質およびその使用
TW555562B (en) 1996-12-27 2003-10-01 Kirin Brewery Method for activation of human antigen-presenting cells, activated human antigen-presenting cells and use thereof
TW575420B (en) * 1997-09-22 2004-02-11 Kirin Brewery Composition for enhancing cellular immunogenicity comprising alpha-glycosylceramides
JP4787445B2 (ja) * 2000-01-14 2011-10-05 株式会社明治 抗原特異的ＩｇＥ抗体産生抑制剤
JP2002030093A (ja) * 2000-03-13 2002-01-29 Nof Corp グリコシルセラミドの精製方法
CA2459482C (en) * 2001-08-16 2010-09-28 Daiichi Suntory Pharma Co., Ltd. Novel glycolipid and medicine for autoimmune disease containing the same as active ingredient
AU2003266530A1 (en) * 2002-09-20 2004-04-08 Kirin Beer Kabushiki Kaisha HEPATITIS C VIRUS INHIBITOR COMPRISING Alpha-GLYCOSYLCERAMIDE AS THE ACTIVE INGREDIENT
JP4585172B2 (ja) * 2003-01-31 2010-11-24 森永乳業株式会社 骨形成促進剤
EP1619199B1 (de) * 2003-02-14 2013-12-18 Japan as represented by President of National Center of Neurology and Psychiatry Ministry of Health Glykolipid-derivate, herstellungsverfahren dafür, zwischenprodukte für deren synthese und herstellungsverfahren für die zwischenprodukte
JP4753089B2 (ja) * 2004-12-20 2011-08-17 株式会社岡安商店 体内脂肪の分解促進作用を有する組成物及びそれを含有する食品又は食品配合剤
JP2007070311A (ja) * 2005-09-09 2007-03-22 Gunma Univ α−ガラクトシルセラミドからなる感染症予防剤及び感染症治療剤
EP1776963A1 (de) 2005-10-19 2007-04-25 Gbf-Gesellschaft Für Biotechnologische Forschung Mbh Hexosylceramiden als Adjuvantien und ihre Verwendung in pharmazeutischen Zusammensetzungen
WO2008047174A1 (en) * 2006-10-18 2008-04-24 Centre National De La Recherche Scientifique Alpha-galactosylceramide analogs, their methods of manufacture, intermediate compounds useful in these methods, and pharmaceutical compositions containing them
KR100868959B1 (ko) * 2006-12-30 2008-11-17 재단법인서울대학교산학협력재단 알파-갈락토실세라마이드 유도체, 이의 약학적으로 허용가능한 염, 이의 제조방법 및 이를 유효성분으로 함유하는면역보조용 약학적 조성물
EP2117583B1 (de) 2007-02-21 2013-05-22 Vib Vzw Kombinationstherapie mit TNF und alpha-Galactosylceramid
JP4995172B2 (ja) * 2008-10-10 2012-08-08 壽製薬株式会社 糖脂質誘導体、その製造方法並びにそれを有効成分とする医薬
AU2010213568B2 (en) 2009-02-16 2014-11-20 Cerenis Therapeutics Holding Sa Apolipoprotein A-I Mimics
JP5025692B2 (ja) * 2009-07-06 2012-09-12 壽製薬株式会社 糖脂質誘導体の製造方法
JP5095683B2 (ja) * 2009-07-06 2012-12-12 壽製薬株式会社 新規糖脂質誘導体及びこれを有効成分とする製剤
JP2010254718A (ja) * 2010-08-13 2010-11-11 Morinaga Milk Ind Co Ltd 骨形成促進剤
CN106167483B (zh) 2010-10-18 2019-02-15 塞伦尼斯医疗控股有限公司 可用于胆固醇动员的化合物、组合物和方法
EP2647384B1 (de) 2010-12-02 2018-05-23 Riken IMMUNTHERAPIE MIT ALLO-NKT-ZELLEN, ZELLEN FÜR DIE IMMUNTHERAPIE MIT UMGEORDNETER aplha KETTE DES T-ZELL REZEPTOR (TCR)-GENS IN GLEICHMÄSSIGE V alpha-J alpha-ANORDNUNG UND LAGERUNG VON NKT-ZELLEN AUS DIESEN ZELLEN
WO2014021464A1 (ja) * 2012-08-03 2014-02-06 独立行政法人理化学研究所 水酸化ｋｒｎ７０００類縁体及びその用途
EP2903622A1 (de) 2012-10-03 2015-08-12 INSERM - Institut National de la Santé et de la Recherche Médicale Verfahren und pharmazeutische zusammensetzungen zur prophylaktischen behandlung von bakteriellen superinfektionen nach einer influenza mit invarianten nkt-zellagonisten
JP6599233B2 (ja) 2012-11-21 2019-10-30 アンセルム（アンスティチュート・ナシオナル・ドゥ・ラ・サンテ・エ・ドゥ・ラ・ルシェルシュ・メディカル） 急性移植片対宿主病のリスクを決定する方法
WO2017207040A1 (en) 2016-06-01 2017-12-07 Vib Vzw ANTI-CANCER THERAPY USING A LEPTIN ANTAGONIST AND AN iNKT-CELL ACTIVATOR
KR102328367B1 (ko) * 2019-11-05 2021-11-18 한국해양과학기술원 아젤록심 d를 유효성분으로 함유하는 방사선 민감성 증진용 조성물
EP4257140A4 (de) 2020-12-04 2024-11-06 Regimmune Corporation Zubereitung von liposomen mit einer cd1d-ligandenverbindung mit verbesserter pharmakokinetik

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6157594A (ja) * 1984-08-30 1986-03-24 Suntory Ltd ガラクトスフインゴ脂質及びその製造法
JP2588729B2 (ja) * 1987-10-05 1997-03-12 塩野義製薬株式会社 スフィンゴシン誘導体
DE3840044A1 (de) * 1988-11-27 1990-06-07 Behringwerke Ag Glykosphingolipide mit kopplungsfaehiger gruppe im sphingoidanteil, ihre herstellung und verwendung
JP3068910B2 (ja) * 1990-11-08 2000-07-24 麒麟麦酒株式会社 新規スフィンゴ糖脂質、その製造法および使用

Also Published As

Publication number Publication date
GR3030723T3 (en) 1999-11-30
DE69229557D1 (de) 1999-08-12
AU1666492A (en) 1993-04-05
HU223839B1 (hu) 2005-02-28
NO180338B (no) 1996-12-23
PT100736A (pt) 1993-09-30
TW197446B (de) 1993-01-01
SG44031A1 (en) 1997-11-14
FI940851A7 (fi) 1994-02-23
KR100220793B1 (ko) 1999-10-01
WO1993005055A1 (fr) 1993-03-18
NO940598D0 (no) 1994-02-22
AU665536B2 (en) 1996-01-11
CA2116442A1 (en) 1993-03-18
HU9400596D0 (en) 1994-05-30
EP0609437A4 (en) 1994-08-24
NO940598L (de) 1994-04-27
DK0609437T3 (da) 2000-01-31
HK1009967A1 (en) 1999-09-17
FI940851A0 (fi) 1994-02-23
JP2774194B2 (ja) 1998-07-09
FI105189B (fi) 2000-06-30
DE69229557T2 (de) 1999-11-25
EP0609437B1 (de) 1999-07-07
EP0609437A1 (de) 1994-08-10
NO180338C (no) 1997-04-02
ATE181922T1 (de) 1999-07-15
JPH0559081A (ja) 1993-03-09
CA2116442C (en) 2000-09-05
PT100736B (pt) 1999-04-30
ES2134213T3 (es) 1999-10-01
HUT70435A (en) 1995-10-30

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