ZA93162B - Esters of acyl carnitines with long-chain aliphatic alcohols and pharmaceutical compositions containing same having antibacterial activity. - Google Patents

Esters of acyl carnitines with long-chain aliphatic alcohols and pharmaceutical compositions containing same having antibacterial activity.

Info

Publication number
ZA93162B
ZA93162B ZA93162A ZA93162A ZA93162B ZA 93162 B ZA93162 B ZA 93162B ZA 93162 A ZA93162 A ZA 93162A ZA 93162 A ZA93162 A ZA 93162A ZA 93162 B ZA93162 B ZA 93162B
Authority
ZA
South Africa
Prior art keywords
esters
pharmaceutical compositions
antibacterial activity
long
compositions containing
Prior art date
Application number
ZA93162A
Other languages
English (en)
Inventor
Mose Santaniello
Domenico Misiti
Maria Ornella Tinti
Piero Foresta
Original Assignee
Sigma Tau Ind Farmaceuti
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sigma Tau Ind Farmaceuti filed Critical Sigma Tau Ind Farmaceuti
Publication of ZA93162B publication Critical patent/ZA93162B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C225/00—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones
    • C07C225/02—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to acyclic carbon atoms of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/22—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated the carbon skeleton being further substituted by oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ZA93162A 1992-01-16 1993-01-11 Esters of acyl carnitines with long-chain aliphatic alcohols and pharmaceutical compositions containing same having antibacterial activity. ZA93162B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITRM920027A IT1254135B (it) 1992-01-16 1992-01-16 Esteri di acil carnitine con alcooli alifatici a lunga catena e composizioni farmaceutiche che li contengono, ad attivita' antibatterica.

Publications (1)

Publication Number Publication Date
ZA93162B true ZA93162B (en) 1993-09-30

Family

ID=11400572

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA93162A ZA93162B (en) 1992-01-16 1993-01-11 Esters of acyl carnitines with long-chain aliphatic alcohols and pharmaceutical compositions containing same having antibacterial activity.

Country Status (13)

Country Link
US (2) US5498632A (de)
EP (1) EP0552137B1 (de)
JP (1) JP3294653B2 (de)
KR (1) KR100251888B1 (de)
AT (1) ATE144492T1 (de)
CA (1) CA2087085C (de)
DE (1) DE69305540T2 (de)
DK (1) DK0552137T3 (de)
ES (1) ES2093395T3 (de)
GR (1) GR3021479T3 (de)
HK (1) HK1005724A1 (de)
IT (1) IT1254135B (de)
ZA (1) ZA93162B (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1261828B (it) 1993-07-14 1996-06-03 Sigma Tau Ind Farmaceuti Esteri di acil l-carnitine e composizioni farmaceutiche che li contengono per il trattamento dello shock endotossico.
US5741816A (en) 1994-06-20 1998-04-21 Tanabe Seiyaku Co., Ltd. Hair-growth agent
IT1274156B (it) * 1994-09-08 1997-07-15 Avantgarde Spa "sale della l-carnitina e composizioni farmaceutiche che lo contengonoper il trattamento di affezioni cutanee"
IT1274157B (it) * 1994-09-08 1997-07-15 Avantgarde Spa "sale della l-carnitina e composizioni farmaceutiche che lo contengonoper il trattamento di affezioni cutanee"
JPH08133971A (ja) * 1994-09-16 1996-05-28 Toyama Chem Co Ltd 抗ヘリコバクター剤
IT1283955B1 (it) * 1996-03-20 1998-05-07 Sigma Tau Ind Farmaceuti Bis alcanoil esteri della carnitina ad attivita' antibatterica, antimicotica ed antiprotozoaria.
KR100513996B1 (ko) * 1996-11-21 2005-12-07 아지노모토 가부시키가이샤 연속발효에의한l-글루탐산의제조방법
US6403124B1 (en) * 1997-04-16 2002-06-11 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Storage and maintenance of blood products including red blood cells and platelets
AU2004283464B8 (en) 2003-10-15 2011-04-14 Syncore Biotechnology Co., Ltd Method of administering cationic liposomes comprising an active drug
CN1852659B (zh) * 2003-10-16 2011-02-09 泰克康姆集团公司 具有降低的血糖应答的可消化性降低的碳水化合物食物
US20050232911A1 (en) * 2004-04-19 2005-10-20 Schreiber Brian D Prevention and treatment of metabolic abnormalities associated with excess intramyocellular lipid
JP5700909B2 (ja) 2005-05-04 2015-04-15 メディゲーネ アクチエンゲゼルシャフトＭｅｄｉＧｅｎｅ ＡＧ パクリタキセルを含む陽イオン性リポソーム製剤を投与する方法
RU2448697C2 (ru) 2006-03-22 2012-04-27 Медигене Аг Лечение рака молочной железы, негативного по трем рецепторам
EP2394640A1 (de) 2010-05-21 2011-12-14 MediGene AG Verbesserte liposomale Formulierungen von lipophilen Verbindungen
WO2011147926A2 (en) 2010-05-26 2011-12-01 Erik Reimhult Magnetically responsive membrane structures
PT2825156T (pt) 2012-03-16 2017-11-02 Merck Patent Gmbh Aminoácidos lipídicos de direcionamento
AU2013231819B2 (en) 2012-03-16 2017-07-20 Merck Patent Gmbh Aminoacid lipids
JP7305088B2 (ja) * 2019-03-06 2023-07-10 源至技術有限公司 動物用飼料添加物の調製にγ－第四級アンモニウム酪酸エステル化合物の適用

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH588443A5 (de) * 1974-09-25 1977-06-15 Lonza Ag
CH596147A5 (de) * 1974-09-25 1978-02-28 Lonza Ag
IT1116037B (it) * 1979-04-23 1986-02-10 Sigma Tau Ind Farmaceuti Esteri e ammidi di acil carnitine loro procedimenti di preparazione e loro uso terapeutico
IT1147079B (it) * 1980-05-30 1986-11-19 Sigma Tau Ind Farmacuetiche Ri Esteri di alcossi-acil derivati della carnitina procedimento per la loro preparatione e composizioni farmaceutiche che li contengono
IT1170861B (it) * 1981-03-31 1987-06-03 Sigma Tau Ind Farmaceuti Ester di mercaptoacil-carnitine procedimento per la loro preparazione e loro uso terapeutico
IT1191945B (it) * 1986-06-04 1988-03-31 Avantgarde Spa N-alchilammidi della d(+)-carnitina dotate di attivita' antibatterica,procedimento per la loro preparazione e composizioni farmaceutiche e cosmetiche che le contengono
IT1235494B (it) * 1987-12-02 1992-09-04 Avantgarde Spa N-alchilammidi della dl e l(-)carnitina dotate di attivita' antibatterica, procedimento per la loro preparazione e composizioni farmaceutiche e cosmetiche che le contengono
IT1231751B (it) * 1989-04-12 1991-12-21 Sigma Tau Ind Farmaceuti Procedimento per la produzione di r(+) amminocarnitina e s(-) amminocarnitina
IT1231944B (it) * 1989-05-05 1992-01-16 Sigma Tau Ind Farmaceuti Composizione farmaceutica per il trattamento di protozoosi, particolarmente della tripasonomiasi comprendente d-carnitina o un alcanoilderivato della d-carnitina
IT1240775B (it) * 1990-02-23 1993-12-17 Sigma Tau Ind Farmaceuti Esteri della l-carnitina e di acil-l-carnitine con l'acido beta-idrossibutirrico e composizioni farmaceutiche che li contengono per la inibizione della degenerazione neuronale, della proteolisi epatica e nel trattamento del coma.

Also Published As

Publication number Publication date
ES2093395T3 (es) 1996-12-16
IT1254135B (it) 1995-09-08
EP0552137A3 (en) 1993-10-20
ITRM920027A1 (it) 1993-07-16
DE69305540T2 (de) 1997-03-06
JPH05339218A (ja) 1993-12-21
HK1005724A1 (en) 1999-01-22
ATE144492T1 (de) 1996-11-15
EP0552137B1 (de) 1996-10-23
DE69305540D1 (de) 1996-11-28
US5498632A (en) 1996-03-12
CA2087085A1 (en) 1993-07-17
ITRM920027A0 (it) 1992-01-16
DK0552137T3 (da) 1996-11-18
US5498633A (en) 1996-03-12
EP0552137A2 (de) 1993-07-21
KR930016391A (ko) 1993-08-26
JP3294653B2 (ja) 2002-06-24
GR3021479T3 (en) 1997-01-31
CA2087085C (en) 2003-12-16
KR100251888B1 (ko) 2000-05-01

Similar Documents

Publication Publication Date Title
GR3021479T3 (en) Esters of acyl carnitines with long-chain aliphatic alcohols and pharmaceutical compositions containing same having antibacterial activity
SG32564G (en) Tetralin esters of phenols or benzoic acids having retinoid like activity
HU9201213D0 (en) Pyrazolo-piridin-derivatives and process for their production
AU1919988A (en) Nitric ester derivative
ZA911728B (en) Benzisothiazolinone-1-dioxide derivatives as elastase inhibitors
EP0218441A3 (en) Cosmetic composition
ITRM910327A1 (it) Uso di esteri di acil l-carnitine con l'acido gamma-idrossibutirrico per produrre composizioni farmaceutiche per il trattamento di epatopatie
ATE157348T1 (de) Ester von l-carnitin und acyl-l-carnitin, mit entspannender wirkung, selektiv auf den gastrointestinaltrakt und sie enthaltende pharmazeutische zusammensetzungen
DE3760202D1 (en) Phosphorylalkanolamide derivatives of l-carnitine and pharmaceutical compositions containing same
EP0309421A3 (en) O-alkanoyl derivatives of 3-amino-2-hydroxypropanesulfonic acid having anticonvulsivant activity and pharmaceutical compositions containing same for the therapeutical treatment of epilepsy
EP0552138A3 (en) Esters of acyl carnitines with long-chain aliphatic alcohols and pharmaceutical compositions containing same having antimycotic activity
NZ334119A (en) Use of pentynoic acid derivatives as neurotrophic and antiproliferative agents
DE69410866D1 (de) Verwendung von Ester von Acyl-L-Carnitin mit Gammahydroxybuttersäure zur Behandlung von Alkoholismus