ZA977406B - Process for preparing intermediates to florfenicol. - Google Patents

Process for preparing intermediates to florfenicol.

Info

Publication number: ZA977406B
Authority: ZA; South Africa
Prior art keywords: florfenicol; preparing intermediates; intermediates; preparing
Prior art date: 1996-08-19

Application number

ZA9707406A

Other languages

English (en)

Inventor

James C Towson

Dhiru B Vashi

Original Assignee

Schering Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-08-19

Filing date

1997-08-18

Publication date

1998-02-18

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24808601&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ZA977406(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1997-08-18 Application filed by Schering Corp filed Critical Schering Corp

1998-02-18 Publication of ZA977406B publication Critical patent/ZA977406B/xx

Links

AYIRNRDRBQJXIF-NXEZZACHSA-N (-)-Florfenicol Chemical compound CS(=O)(=O)C1=CC=C([C@@H](O)[C@@H](CF)NC(=O)C(Cl)Cl)C=C1 AYIRNRDRBQJXIF-NXEZZACHSA-N 0.000 title 1
229960003760 florfenicol Drugs 0.000 title 1
239000000543 intermediate Substances 0.000 title 1
238000004519 manufacturing process Methods 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D263/28—Nitrogen atoms not forming part of a nitro radical

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

ZA9707406A 1996-08-19 1997-08-18 Process for preparing intermediates to florfenicol. ZA977406B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US08/699,271 US5663361A (en)	1996-08-19	1996-08-19	Process for preparing intermediates to florfenicol

Publications (1)

Publication Number	Publication Date
ZA977406B true ZA977406B (en)	1998-02-18

Family

ID=24808601

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA9707406A ZA977406B (en)	1996-08-19	1997-08-18	Process for preparing intermediates to florfenicol.

Country Status (30)

Country	Link
US (1)	US5663361A (da)
EP (1)	EP0922040B2 (da)
JP (1)	JP3274868B2 (da)
KR (1)	KR100286851B1 (da)
CN (1)	CN1097583C (da)
AR (1)	AR008298A1 (da)
AT (1)	ATE283847T1 (da)
AU (1)	AU714495B2 (da)
BR (1)	BR9711318B1 (da)
CA (1)	CA2264116C (da)
CO (1)	CO4560550A1 (da)
CZ (1)	CZ297915B6 (da)
DE (1)	DE69731835T3 (da)
DK (1)	DK0922040T3 (da)
ES (1)	ES2234026T5 (da)
HU (1)	HU229610B1 (da)
ID (1)	ID18047A (da)
IL (1)	IL128574A (da)
MY (1)	MY115679A (da)
NO (1)	NO312962B1 (da)
NZ (1)	NZ334111A (da)
PE (1)	PE99798A1 (da)
PL (2)	PL198553B1 (da)
PT (1)	PT922040E (da)
SI (1)	SI0922040T1 (da)
SK (1)	SK286124B6 (da)
TR (2)	TR200800474T2 (da)
TW (1)	TW381075B (da)
WO (1)	WO1998007709A1 (da)
ZA (1)	ZA977406B (da)

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CN1173933C (zh) *	2001-06-01	2004-11-03	中国科学院上海有机化学研究所	一种从l型取代苯丝氨酸酯制备d－（－）－苏式1－r－取代苯基－2－二氯乙酰氨基－3－氟－1－丙醇的方法
AU2003249503A1 (en) *	2002-03-08	2003-09-29	Schering-Plough, Ltd.	Novel florfenicol-type antibiotics
PE20050386A1 (es)	2003-05-29	2005-06-23	Schering Plough Ltd	Composiciones farmaceuticas de florfenicol
US7439268B2 (en) *	2003-07-18	2008-10-21	Idexx Laboratories	Compositions containing prodrugs of florfenicol and methods of use
US20050049210A1 (en) *	2003-08-27	2005-03-03	Idexx Laboratories, Inc.	Methods for the controlled delivery of pharmacologically active compounds
US7126005B2 (en) *	2003-10-06	2006-10-24	Aurobindo Pharma Limited	Process for preparing florfenicol
CA2576589C (en) *	2004-08-13	2013-11-12	Schering-Plough Ltd.	Pharmaceutical formulation comprising an antibiotic, a triazole and a corticosteroid
DE602005009381D1 (de)	2004-09-23	2008-10-09	Schering Plough Ltd	Bekämpfung von parasiten in tieren durch verwendung neuer trifluormethansulfonanilidoximetherderivate
JP4750126B2 (ja) *	2004-11-19	2011-08-17	シェーリング−プラウ・リミテッド	殺寄生虫薬２−フェニル−３−（１ｈ−ピロール−２−イル）アクリロニトリル誘導体の使用による動物における寄生虫の制御
US8680154B2 (en) *	2004-12-21	2014-03-25	Intervet International B.V.	Injectable veterinary composition
EP1890547A2 (en) *	2005-06-09	2008-02-27	Schering-Plough Ltd.	Control of parasites in animals by n-[(phenyloxy)phenyl]-1,1,1-trifluoromethanesulfonamide and n-[(phenylsulfanyl)phenyl]-1,1,1-trifluoromethanesulfonamide derivatives
JP5113754B2 (ja) *	2005-09-07	2013-01-09	シェーリング−プラウ・リミテッド	エステルオキサゾリジン化合物を調製するためのプロセスおよびそれらのフロルフェニコールへの変換
US8119667B2 (en) *	2005-12-29	2012-02-21	Schering-Plough Animal Health Corporation	Carbonates of fenicol antibiotics
US7518017B2 (en)	2006-02-17	2009-04-14	Idexx Laboratories	Fenicol compounds and methods synthesizing 2-trifluoroacetamido-3-substituted propiophenone compounds
US20070238700A1 (en) *	2006-04-10	2007-10-11	Winzenberg Kevin N	N-phenyl-1,1,1-trifluoromethanesulfonamide hydrazone derivative compounds and their usage in controlling parasites
CN101605756A (zh) *	2006-12-13	2009-12-16	先灵-普劳有限公司	氟苯尼考及其类似物的水溶性前药
WO2008076256A1 (en) *	2006-12-13	2008-06-26	Schering-Plough Ltd.	Water-soluble prodrugs of chloramphenicol, thiamphenicol, and analogs thereof
WO2008133901A1 (en) *	2007-04-27	2008-11-06	Schering-Plough Ltd.	Compounds and methods for enhancing solubility of florfenicol and structurally-related antibiotics using cyclodextrins
KR20100022999A (ko) *	2007-05-30	2010-03-03	쉐링-프라우 리미티드	플로르페니콜에 대한 중간체로서 유용한 옥사졸린-보호된 아미노디올 화합물의 제조방법
TWI430995B (zh)	2007-06-26	2014-03-21	Du Pont	萘異唑啉無脊椎有害動物控制劑
DK2182945T3 (da)	2007-06-27	2015-11-16	Du Pont	Fremgangsmåde til bekæmpelse af skadedyr hos dyr
CN101796037A (zh) *	2007-07-25	2010-08-04	英特威国际有限公司	制备噁唑烷-氨基二醇和噁唑烷酮-氨基二醇及相关中间体的方法
US7550625B2 (en) *	2007-10-19	2009-06-23	Idexx Laboratories	Esters of florfenicol
PL2217207T3 (pl) *	2007-11-09	2019-05-31	Intervet Int Bv	Preparat o szybkim uwalnianiu w postaci stałej, jego przygotowanie i zastosowanie
TWI401023B (zh)	2008-02-06	2013-07-11	Du Pont	中離子農藥
WO2010014566A2 (en) *	2008-07-30	2010-02-04	Intervet International B.V.	Process for preparing oxazoline-protected aminodiol compounds useful as intermediates to florfenicol
AU2010279587A1 (en)	2009-08-05	2012-02-09	E. I. Du Pont De Nemours And Company	Mesoionic pesticides
EP2461684A2 (en)	2009-08-05	2012-06-13	E. I. du Pont de Nemours and Company	Mesoionic pesticides
UA110924C2 (uk)	2009-08-05	2016-03-10	Е. І. Дю Пон Де Немур Енд Компані	Мезоіонні пестициди
UA107804C2 (xx)	2009-08-05	2015-02-25	Du Pont	Суміші мезоіонних пестицидів
BRPI1002023A2 (pt)	2010-03-01	2011-10-25	Nanocore Biotecnologia S A	forma farmacêutica sólida de dissolução rápida para tratamento de infecções bacterianas
EP2576523B1 (en)	2010-05-27	2016-01-13	E. I. du Pont de Nemours and Company	Crystalline form of 4-[5 - [3 -chloro-5 -(trifluoromethyl)phenyl] -4,5 -dihydro-5 -(trifluoromethyl)-3 - isoxazolyl]-n-[2-oxo-2-[(2,2,2-trifluoroethyl)amino]ethyl]-1- naphthalenecarboxamide
WO2012087630A1 (en)	2010-12-20	2012-06-28	E.I. Du Pont De Nemours And Company	Pyridine and pyrimidine compounds for controlling invertebrate
WO2013158422A1 (en)	2012-04-17	2013-10-24	E. I. Du Pont De Nemours And Company	Heterocyclic compounds for controlling invertebrate pests
CN102911133B (zh) *	2012-10-31	2014-07-02	绍兴民生医药有限公司	(4r,5r)-2-二氯甲基-4,5-二氢-5-(4-甲砜基苯基)-4-恶唑甲醇的纯化方法
CN103254147B (zh) *	2013-04-19	2016-04-06	浙江科技学院	一种d-苏式-2-(二氯甲基)-4,5-二氢-5-[对-（甲砜基）苯基]-4-噁唑甲醇的制备方法
CN106278964B (zh) *	2016-07-31	2018-01-16	浙江润康药业有限公司	氟苯尼考的制备方法
CN106631872A (zh) *	2016-12-13	2017-05-10	浙江普洛家园药业有限公司	一种氟苯尼考类似物中间体的合成方法
CN110272856B (zh) *	2019-05-08	2022-05-03	江南大学	一种表达d-苏氨酸醛缩酶的重组菌及其构建方法与应用
CN117466787B (zh) *	2023-12-28	2024-03-22	山东国邦药业有限公司	一种氟苯尼考中间体的制备方法

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US2759001A (en) *	1952-03-01	1956-08-14	Parke Davis & Co	Process for the production of delta2-oxazolines
US4361557A (en) *	1980-01-28	1982-11-30	Schering Corporation	1-Aryl-2-acylamido-3-fluoro-1-propanol acylates, methods for their use as anti-bacterial agents and compositions useful therefor
DE3486438T2 (de) *	1983-06-02	1998-08-13	Schering Plouth Ltd	Verfahren zur Herstellung von 1-(Phenyl)-1-hydroxy-2-amino-3-fluor-propan-Derivaten
US4876352A (en) *	1988-09-14	1989-10-24	Schering Corporation	Pressurized fluorination of hydroxy alkyl groups
KR920701469A (ko) †	1989-05-15	1992-08-11	스테이너 브이. 캔스태드	향균성 화합물 및 이의 중간물질의 제조방법
HU9301182D0 (en) *	1990-10-25	1993-08-30	Schering Corp	Method for producing fluoro-phenicole, its analogues and intermediary compounds

1996
- 1996-08-19 US US08/699,271 patent/US5663361A/en not_active Expired - Lifetime
1997
- 1997-08-15 CO CO97047276A patent/CO4560550A1/es unknown
- 1997-08-15 AR ARP970103736A patent/AR008298A1/es not_active Application Discontinuation
- 1997-08-18 TR TR2008/00474T patent/TR200800474T2/xx unknown
- 1997-08-18 IL IL12857497A patent/IL128574A/en not_active IP Right Cessation
- 1997-08-18 ES ES97938263T patent/ES2234026T5/es not_active Expired - Lifetime
- 1997-08-18 EP EP97938263.7A patent/EP0922040B2/en not_active Expired - Lifetime
- 1997-08-18 CN CN97198768A patent/CN1097583C/zh not_active Expired - Lifetime
- 1997-08-18 PT PT97938263T patent/PT922040E/pt unknown
- 1997-08-18 PL PL378741A patent/PL198553B1/pl not_active IP Right Cessation
- 1997-08-18 JP JP51080598A patent/JP3274868B2/ja not_active Expired - Lifetime
- 1997-08-18 AU AU40638/97A patent/AU714495B2/en not_active Expired
- 1997-08-18 CZ CZ0054099A patent/CZ297915B6/cs not_active IP Right Cessation
- 1997-08-18 WO PCT/US1997/014205 patent/WO1998007709A1/en not_active Ceased
- 1997-08-18 SK SK199-99A patent/SK286124B6/sk not_active IP Right Cessation
- 1997-08-18 DE DE69731835T patent/DE69731835T3/de not_active Expired - Lifetime
- 1997-08-18 SI SI9730688T patent/SI0922040T1/xx unknown
- 1997-08-18 ID IDP972887A patent/ID18047A/id unknown
- 1997-08-18 PL PL331644A patent/PL196454B1/pl not_active IP Right Cessation
- 1997-08-18 MY MYPI97003778A patent/MY115679A/en unknown
- 1997-08-18 ZA ZA9707406A patent/ZA977406B/xx unknown
- 1997-08-18 PE PE1997000728A patent/PE99798A1/es not_active Application Discontinuation
- 1997-08-18 BR BRPI9711318-2A patent/BR9711318B1/pt not_active IP Right Cessation
- 1997-08-18 DK DK97938263T patent/DK0922040T3/da active
- 1997-08-18 HU HU9904166A patent/HU229610B1/hu unknown
- 1997-08-18 AT AT97938263T patent/ATE283847T1/de active
- 1997-08-18 TR TR1999/00354T patent/TR199900354T2/xx unknown
- 1997-08-18 CA CA002264116A patent/CA2264116C/en not_active Expired - Lifetime
- 1997-08-18 NZ NZ334111A patent/NZ334111A/en not_active IP Right Cessation
- 1997-08-19 TW TW086111823A patent/TW381075B/zh not_active IP Right Cessation
1999
- 1999-02-18 KR KR1019997001290A patent/KR100286851B1/ko not_active Expired - Lifetime
- 1999-02-18 NO NO19990756A patent/NO312962B1/no not_active IP Right Cessation

Also Published As

Publication number	Publication date
EP0922040B1 (en)	2004-12-01
ES2234026T3 (es)	2005-06-16
HUP9904166A2 (hu)	2000-05-28
SI0922040T1 (en)	2005-02-28
AU4063897A (en)	1998-03-06
MY115679A (en)	2003-08-30
AR008298A1 (es)	1999-12-29
JP2000501424A (ja)	2000-02-08
TW381075B (en)	2000-02-01
NO990756D0 (no)	1999-02-18
PE99798A1 (es)	1998-12-28
EP0922040B2 (en)	2013-07-17
PL196454B1 (pl)	2008-01-31
EP0922040A1 (en)	1999-06-16
NZ334111A (en)	1999-10-28
BR9711318A (pt)	1999-08-17
CA2264116A1 (en)	1998-02-26
ATE283847T1 (de)	2004-12-15
BR9711318B1 (pt)	2009-01-13
ID18047A (id)	1998-02-19
PL198553B1 (pl)	2008-06-30
CZ54099A3 (cs)	1999-07-14
HK1017890A1 (en)	1999-12-03
AU714495B2 (en)	2000-01-06
IL128574A (en)	2002-04-21
KR20000068178A (ko)	2000-11-25
SK19999A3 (en)	2000-02-14
NO990756L (no)	1999-02-18
ES2234026T5 (es)	2013-11-12
CN1097583C (zh)	2003-01-01
JP3274868B2 (ja)	2002-04-15
KR100286851B1 (ko)	2001-04-16
IL128574A0 (en)	2000-01-31
HU229610B1 (en)	2014-03-28
PL331644A1 (en)	1999-08-02
US5663361A (en)	1997-09-02
CZ297915B6 (cs)	2007-04-25
DK0922040T3 (da)	2005-04-04
CN1233244A (zh)	1999-10-27
CO4560550A1 (es)	1998-02-10
TR199900354T2 (xx)	1999-05-21
HUP9904166A3 (en)	2001-11-28
DE69731835T3 (de)	2013-12-05
DE69731835D1 (de)	2005-01-05
NO312962B1 (no)	2002-07-22
CA2264116C (en)	2002-07-02
SK286124B6 (sk)	2008-04-07
TR200800474T2 (tr)	2008-04-21
DE69731835T2 (de)	2005-07-21
WO1998007709A1 (en)	1998-02-26
PT922040E (pt)	2005-02-28

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