DK0922040T3 - Fremgangsmåde til fremstilling af mellemprodukter til florfenicol - Google Patents

Fremgangsmåde til fremstilling af mellemprodukter til florfenicol

Info

Publication number: DK0922040T3
Authority: DK; Denmark
Prior art keywords: florfenicol; intermediates; preparation
Prior art date: 1996-08-19

Application number

DK97938263T

Other languages

English (en)

Inventor

James C Towson

Dhiru B Vashi

Original Assignee

Schering Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-08-19

Filing date

1997-08-18

Publication date

2005-04-04

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24808601&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0922040(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1997-08-18 Application filed by Schering Corp filed Critical Schering Corp

2005-04-04 Application granted granted Critical

2005-04-04 Publication of DK0922040T3 publication Critical patent/DK0922040T3/da

Links

AYIRNRDRBQJXIF-NXEZZACHSA-N (-)-Florfenicol Chemical compound CS(=O)(=O)C1=CC=C([C@@H](O)[C@@H](CF)NC(=O)C(Cl)Cl)C=C1 AYIRNRDRBQJXIF-NXEZZACHSA-N 0.000 title 1
229960003760 florfenicol Drugs 0.000 title 1
239000000543 intermediate Substances 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D263/28—Nitrogen atoms not forming part of a nitro radical

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

DK97938263T 1996-08-19 1997-08-18 Fremgangsmåde til fremstilling af mellemprodukter til florfenicol DK0922040T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US08/699,271 US5663361A (en)	1996-08-19	1996-08-19	Process for preparing intermediates to florfenicol
EP97938263.7A EP0922040B2 (en)	1996-08-19	1997-08-18	Process for preparing intermediates to florfenicol

Publications (1)

Publication Number	Publication Date
DK0922040T3 true DK0922040T3 (da)	2005-04-04

Family

ID=24808601

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK97938263T DK0922040T3 (da)	1996-08-19	1997-08-18	Fremgangsmåde til fremstilling af mellemprodukter til florfenicol

Country Status (30)

Country	Link
US (1)	US5663361A (da)
EP (1)	EP0922040B2 (da)
JP (1)	JP3274868B2 (da)
KR (1)	KR100286851B1 (da)
CN (1)	CN1097583C (da)
AR (1)	AR008298A1 (da)
AT (1)	ATE283847T1 (da)
AU (1)	AU714495B2 (da)
BR (1)	BR9711318B1 (da)
CA (1)	CA2264116C (da)
CO (1)	CO4560550A1 (da)
CZ (1)	CZ297915B6 (da)
DE (1)	DE69731835T3 (da)
DK (1)	DK0922040T3 (da)
ES (1)	ES2234026T5 (da)
HU (1)	HU229610B1 (da)
ID (1)	ID18047A (da)
IL (1)	IL128574A (da)
MY (1)	MY115679A (da)
NO (1)	NO312962B1 (da)
NZ (1)	NZ334111A (da)
PE (1)	PE99798A1 (da)
PL (2)	PL198553B1 (da)
PT (1)	PT922040E (da)
SI (1)	SI0922040T1 (da)
SK (1)	SK286124B6 (da)
TR (2)	TR199900354T2 (da)
TW (1)	TW381075B (da)
WO (1)	WO1998007709A1 (da)
ZA (1)	ZA977406B (da)

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CN1173933C (zh) *	2001-06-01	2004-11-03	中国科学院上海有机化学研究所	一种从l型取代苯丝氨酸酯制备d－（－）－苏式1－r－取代苯基－2－二氯乙酰氨基－3－氟－1－丙醇的方法
CN1649829A (zh) *	2002-03-08	2005-08-03	先灵-普劳有限公司	新型氟苯尼考类抗生素
TW200505425A (en)	2003-05-29	2005-02-16	Schering Plough Ltd	Compositions and method for treating infection in cattle and swine
US7439268B2 (en) *	2003-07-18	2008-10-21	Idexx Laboratories	Compositions containing prodrugs of florfenicol and methods of use
US20050049210A1 (en) *	2003-08-27	2005-03-03	Idexx Laboratories, Inc.	Methods for the controlled delivery of pharmacologically active compounds
US7126005B2 (en) *	2003-10-06	2006-10-24	Aurobindo Pharma Limited	Process for preparing florfenicol
KR101289115B1 (ko) *	2004-08-13	2013-07-23	엠에스디 인터내셔널 홀딩즈 게엠베하	항생제인 트리아졸 및 코르티코스테로이드를 포함하는약제학적 제형
BRPI0515917A (pt)	2004-09-23	2008-08-12	Schering Plough Ltd	controle de parasitas em animais pelo uso de novos derivados de éter de oxima de trifluorometanossulfonanilida
EP1811841B1 (en) *	2004-11-19	2009-10-28	Schering-Plough Ltd.	Control of parasites in animals by the use of parasiticidal 2-phenyl-3-(1h-pyrrol-2-yl) acrylonitrile derivatives
PL1830885T3 (pl) *	2004-12-21	2009-04-30	Intervet Int Bv	Iniekcyjna kompozycja weterynaryjna zawierająca florfenikol
WO2006135648A2 (en) *	2005-06-09	2006-12-21	Schering-Plough Ltd.	Control of parasites in animals by n-[(phenyloxy)phenyl]-1,1,1-trifluoromethanesulfonamide and n-[(phenylsulfanyl)phenyl]-1,1,1-trifluoromethanesulfonamide derivatives
EP1934190A2 (en) *	2005-09-07	2008-06-25	Schering-Plough Ltd.	An improved process for preparing oxazolidine protected aminodiol compounds useful as intermediates to florfenicol
US8119667B2 (en) *	2005-12-29	2012-02-21	Schering-Plough Animal Health Corporation	Carbonates of fenicol antibiotics
US7518017B2 (en)	2006-02-17	2009-04-14	Idexx Laboratories	Fenicol compounds and methods synthesizing 2-trifluoroacetamido-3-substituted propiophenone compounds
US20070238700A1 (en) *	2006-04-10	2007-10-11	Winzenberg Kevin N	N-phenyl-1,1,1-trifluoromethanesulfonamide hydrazone derivative compounds and their usage in controlling parasites
CA2672795A1 (en) *	2006-12-13	2008-06-26	Schering-Plough Ltd.	Water-soluble prodrugs of chloramphenicol, thiamphenicol, and analogs thereof
WO2008076259A1 (en) *	2006-12-13	2008-06-26	Schering-Plough Ltd.	Water-soluble prodrugs of florfenicol and its analogs
MX2009011642A (es) *	2007-04-27	2010-01-29	Schering Plough Ltd	Compuestos y metodos para potenciar la solubilidad de florfenicol y antibioticos estructuralmente relacionados utilizando ciclodextrinas.
PE20090758A1 (es) *	2007-05-30	2009-06-24	Schering Plough Ltd	Un proceso para la preparacion de compuestos de aminodiol protegidos con oxazolina, utiles como intermediarios para florfenicol
TWI430995B (zh)	2007-06-26	2014-03-21	Du Pont	萘異唑啉無脊椎有害動物控制劑
KR101769728B1 (ko)	2007-06-27	2017-08-18	이 아이 듀폰 디 네모아 앤드 캄파니	동물 해충 방제 방법
US20100210851A1 (en) *	2007-07-25	2010-08-19	Towson James C	Process for preparing oxazolidine- and oxazolidinone-aminodiols
US7550625B2 (en) *	2007-10-19	2009-06-23	Idexx Laboratories	Esters of florfenicol
NZ585219A (en) *	2007-11-09	2012-11-30	Intervet Int Bv	Fast release solid formulation, preparation and use thereof
TWI468407B (zh)	2008-02-06	2015-01-11	Du Pont	中離子農藥
WO2010014566A2 (en) *	2008-07-30	2010-02-04	Intervet International B.V.	Process for preparing oxazoline-protected aminodiol compounds useful as intermediates to florfenicol
UA107804C2 (xx)	2009-08-05	2015-02-25	Du Pont	Суміші мезоіонних пестицидів
US20120122680A1 (en)	2009-08-05	2012-05-17	E.I. Du Pont De Nemours And Company	Mesoionic pesticides
UA110924C2 (uk)	2009-08-05	2016-03-10	Е. І. Дю Пон Де Немур Енд Компані	Мезоіонні пестициди
KR20120050467A (ko)	2009-08-05	2012-05-18	이 아이 듀폰 디 네모아 앤드 캄파니	메소이온성 살충제
BRPI1002023A2 (pt)	2010-03-01	2011-10-25	Nanocore Biotecnologia S A	forma farmacêutica sólida de dissolução rápida para tratamento de infecções bacterianas
UA108881C2 (xx)	2010-05-27	2015-06-25		Кристалічна форма 4-$5-$3-хлор-5-(трифторметил)феніл]-4,5-дигідро-5-(трифторметил)-3-ізоксазоліл]-n-$2-оксо-2-$(2,2,2-трифторетил)аміно]етил]-1-нафталінкарбоксаміду
WO2012087630A1 (en)	2010-12-20	2012-06-28	E.I. Du Pont De Nemours And Company	Pyridine and pyrimidine compounds for controlling invertebrate
WO2013158422A1 (en)	2012-04-17	2013-10-24	E. I. Du Pont De Nemours And Company	Heterocyclic compounds for controlling invertebrate pests
CN102911133B (zh) *	2012-10-31	2014-07-02	绍兴民生医药有限公司	(4r,5r)-2-二氯甲基-4,5-二氢-5-(4-甲砜基苯基)-4-恶唑甲醇的纯化方法
CN103254147B (zh) *	2013-04-19	2016-04-06	浙江科技学院	一种d-苏式-2-(二氯甲基)-4,5-二氢-5-[对-（甲砜基）苯基]-4-噁唑甲醇的制备方法
CN106278964B (zh) *	2016-07-31	2018-01-16	浙江润康药业有限公司	氟苯尼考的制备方法
CN106631872A (zh) *	2016-12-13	2017-05-10	浙江普洛家园药业有限公司	一种氟苯尼考类似物中间体的合成方法
CN110272856B (zh) *	2019-05-08	2022-05-03	江南大学	一种表达d-苏氨酸醛缩酶的重组菌及其构建方法与应用
CN117466787B (zh) *	2023-12-28	2024-03-22	山东国邦药业有限公司	一种氟苯尼考中间体的制备方法

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US2759001A (en)	1952-03-01	1956-08-14	Parke Davis & Co	Process for the production of delta2-oxazolines
US4361557A (en) *	1980-01-28	1982-11-30	Schering Corporation	1-Aryl-2-acylamido-3-fluoro-1-propanol acylates, methods for their use as anti-bacterial agents and compositions useful therefor
EP0677511A3 (en) *	1983-06-02	1996-07-24	Zambon Spa	Intermediates for the production of 1-phenyl-1-hydroxy-2-amino-3-fluoropropane derivatives.
US4876352A (en) *	1988-09-14	1989-10-24	Schering Corporation	Pressurized fluorination of hydroxy alkyl groups
KR920701469A (ko) †	1989-05-15	1992-08-11	스테이너 브이. 캔스태드	향균성 화합물 및 이의 중간물질의 제조방법
NZ250394A (en) *	1990-10-25	1994-10-26	Schering Corp	Fluorinated and hydroxylated oxazoline compounds

1996
- 1996-08-19 US US08/699,271 patent/US5663361A/en not_active Expired - Lifetime
1997
- 1997-08-15 AR ARP970103736A patent/AR008298A1/es not_active Application Discontinuation
- 1997-08-15 CO CO97047276A patent/CO4560550A1/es unknown
- 1997-08-18 HU HU9904166A patent/HU229610B1/hu unknown
- 1997-08-18 PE PE1997000728A patent/PE99798A1/es not_active Application Discontinuation
- 1997-08-18 CN CN97198768A patent/CN1097583C/zh not_active Expired - Lifetime
- 1997-08-18 DE DE69731835T patent/DE69731835T3/de not_active Expired - Lifetime
- 1997-08-18 AU AU40638/97A patent/AU714495B2/en not_active Expired
- 1997-08-18 BR BRPI9711318-2A patent/BR9711318B1/pt not_active IP Right Cessation
- 1997-08-18 WO PCT/US1997/014205 patent/WO1998007709A1/en not_active Ceased
- 1997-08-18 ES ES97938263T patent/ES2234026T5/es not_active Expired - Lifetime
- 1997-08-18 PL PL378741A patent/PL198553B1/pl not_active IP Right Cessation
- 1997-08-18 ID IDP972887A patent/ID18047A/id unknown
- 1997-08-18 ZA ZA9707406A patent/ZA977406B/xx unknown
- 1997-08-18 PT PT97938263T patent/PT922040E/pt unknown
- 1997-08-18 DK DK97938263T patent/DK0922040T3/da active
- 1997-08-18 SK SK199-99A patent/SK286124B6/sk not_active IP Right Cessation
- 1997-08-18 IL IL12857497A patent/IL128574A/en not_active IP Right Cessation
- 1997-08-18 TR TR1999/00354T patent/TR199900354T2/xx unknown
- 1997-08-18 JP JP51080598A patent/JP3274868B2/ja not_active Expired - Lifetime
- 1997-08-18 CA CA002264116A patent/CA2264116C/en not_active Expired - Lifetime
- 1997-08-18 MY MYPI97003778A patent/MY115679A/en unknown
- 1997-08-18 CZ CZ0054099A patent/CZ297915B6/cs not_active IP Right Cessation
- 1997-08-18 TR TR2008/00474T patent/TR200800474T2/xx unknown
- 1997-08-18 EP EP97938263.7A patent/EP0922040B2/en not_active Expired - Lifetime
- 1997-08-18 AT AT97938263T patent/ATE283847T1/de active
- 1997-08-18 NZ NZ334111A patent/NZ334111A/en not_active IP Right Cessation
- 1997-08-18 SI SI9730688T patent/SI0922040T1/xx unknown
- 1997-08-18 PL PL331644A patent/PL196454B1/pl not_active IP Right Cessation
- 1997-08-19 TW TW086111823A patent/TW381075B/zh not_active IP Right Cessation
1999
- 1999-02-18 NO NO19990756A patent/NO312962B1/no not_active IP Right Cessation
- 1999-02-18 KR KR1019997001290A patent/KR100286851B1/ko not_active Expired - Lifetime

Also Published As

Publication number	Publication date
EP0922040B2 (en)	2013-07-17
CO4560550A1 (es)	1998-02-10
US5663361A (en)	1997-09-02
ID18047A (id)	1998-02-19
TW381075B (en)	2000-02-01
PT922040E (pt)	2005-02-28
IL128574A (en)	2002-04-21
JP3274868B2 (ja)	2002-04-15
NO312962B1 (no)	2002-07-22
ES2234026T5 (es)	2013-11-12
DE69731835D1 (de)	2005-01-05
SI0922040T1 (en)	2005-02-28
CA2264116A1 (en)	1998-02-26
ZA977406B (en)	1998-02-18
KR100286851B1 (ko)	2001-04-16
WO1998007709A1 (en)	1998-02-26
BR9711318B1 (pt)	2009-01-13
CN1097583C (zh)	2003-01-01
EP0922040A1 (en)	1999-06-16
HK1017890A1 (en)	1999-12-03
NO990756D0 (no)	1999-02-18
KR20000068178A (ko)	2000-11-25
EP0922040B1 (en)	2004-12-01
SK19999A3 (en)	2000-02-14
CZ54099A3 (cs)	1999-07-14
DE69731835T2 (de)	2005-07-21
CZ297915B6 (cs)	2007-04-25
PE99798A1 (es)	1998-12-28
AU714495B2 (en)	2000-01-06
CN1233244A (zh)	1999-10-27
BR9711318A (pt)	1999-08-17
CA2264116C (en)	2002-07-02
AU4063897A (en)	1998-03-06
NZ334111A (en)	1999-10-28
IL128574A0 (en)	2000-01-31
PL331644A1 (en)	1999-08-02
HUP9904166A2 (hu)	2000-05-28
HUP9904166A3 (en)	2001-11-28
AR008298A1 (es)	1999-12-29
DE69731835T3 (de)	2013-12-05
ES2234026T3 (es)	2005-06-16
NO990756L (no)	1999-02-18
PL198553B1 (pl)	2008-06-30
TR199900354T2 (xx)	1999-05-21
HU229610B1 (en)	2014-03-28
JP2000501424A (ja)	2000-02-08
PL196454B1 (pl)	2008-01-31
SK286124B6 (sk)	2008-04-07
TR200800474T2 (tr)	2008-04-21
MY115679A (en)	2003-08-30
ATE283847T1 (de)	2004-12-15

Publication	Publication Date	Title
DK0922040T3 (da)	2005-04-04	Fremgangsmåde til fremstilling af mellemprodukter til florfenicol
DK1032566T5 (da)	2004-06-28	Fremgangsmåde til fremstilling af citalopram
DK0790226T3 (da)	2000-08-07	Fremgangsmåde til fremstilling af methanol
DK0773940T3 (da)	2003-09-15	Fremgangsmåde til syntese af substituerede sulfoxider
DK0770615T3 (da)	2003-07-14	Fremgangsmåde til fremstilling af dihalogenazolopyrimidiner
DK0857784T3 (da)	2007-01-15	Fremgangsmåde til fremstilling af L-lysin
DK0811682T3 (da)	2004-05-17	Fremgangsmåde til fremstilling af L-lysin
DK0854189T3 (da)	2007-01-15	Fremgangsmåde til fremstilling af L-lysin
DK1123284T3 (da)	2003-04-28	Fremgangsmåde til fremstilling af citalopram
DK0754756T3 (da)	2006-03-13	Fremgangsmåde til fremstilling af L-lysin
DK0916675T3 (da)	2003-10-27	Fremgangsmåde til fremstilling af sildenafil
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DK1053217T3 (da)	2003-09-15	Fremgangsmåde til fremstilling af n-propanol
DK0939749T3 (da)	2001-11-05	Fremgangsmåde til fremstilling af benzylethere
DK0996642T3 (da)	2006-05-08	Fremgangsmåde til fremstilling af heparin
DK0970939T3 (da)	2003-04-07	Fremgangsmåde til fremstilling af methanol
DK0946531T3 (da)	2006-02-13	Fremgangsmåde til fremstilling af thiazol-derivater
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