AP2008004437A0 - Pyrazolo Ä4,3-DÜ pyrimidin-5-yl) derivative used as PDE5 inhibitors - Google Patents

Pyrazolo Ä4,3-DÜ pyrimidin-5-yl) derivative used as PDE5 inhibitors

Info

Publication number: AP2008004437A0
Authority: AP; ARIPO
Prior art keywords: pyrazolo; pyrimidin; derivative used; pde5 inhibitors; pde5
Prior art date: 2005-11-10

Application number

AP2008004437A

Other languages

English (en)

Inventor

Michael Brent Tollefson

Original Assignee

Pfizer Prod Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2005-11-10

Filing date

2006-10-31

Publication date

2008-04-30

2006-10-31 Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc

2008-04-30 Publication of AP2008004437A0 publication Critical patent/AP2008004437A0/xx

Links

229940123333 Phosphodiesterase 5 inhibitor Drugs 0.000 title 1
239000002590 phosphodiesterase V inhibitor Substances 0.000 title 1
125000004528 pyrimidin-5-yl group Chemical group N1=CN=CC(=C1)* 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Diabetes (AREA)
Cardiology (AREA)
Endocrinology (AREA)
Heart & Thoracic Surgery (AREA)
Pain & Pain Management (AREA)
Physical Education & Sports Medicine (AREA)
Reproductive Health (AREA)
Urology & Nephrology (AREA)
Hematology (AREA)
Ophthalmology & Optometry (AREA)
Orthopedic Medicine & Surgery (AREA)
Obesity (AREA)
Dermatology (AREA)
Psychiatry (AREA)
Gynecology & Obstetrics (AREA)
Pregnancy & Childbirth (AREA)
Vascular Medicine (AREA)
Rheumatology (AREA)
Addiction (AREA)
Psychology (AREA)
Hospice & Palliative Care (AREA)
Emergency Medicine (AREA)

AP2008004437A 2005-11-10 2006-10-31 Pyrazolo Ä4,3-DÜ pyrimidin-5-yl) derivative used as PDE5 inhibitors AP2008004437A0 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US73532005P	2005-11-10	2005-11-10
PCT/IB2006/003132 WO2007054778A1 (en)	2005-11-10	2006-10-31	Pyrazolo[4,3-d]pyrimidin-5-yl)derivative used as pde5 inhibitors

Publications (1)

Publication Number	Publication Date
AP2008004437A0 true AP2008004437A0 (en)	2008-04-30

Family

ID=37685872

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AP2008004437A AP2008004437A0 (en)	2005-11-10	2006-10-31	Pyrazolo Ä4,3-DÜ pyrimidin-5-yl) derivative used as PDE5 inhibitors

Country Status (29)

Country	Link
US (2)	US20090156618A1 (sr)
EP (1)	EP1948661B1 (sr)
JP (1)	JP4208959B1 (sr)
KR (1)	KR101012592B1 (sr)
CN (1)	CN101305007B (sr)
AP (1)	AP2008004437A0 (sr)
AR (1)	AR057885A1 (sr)
AT (1)	ATE435865T1 (sr)
AU (1)	AU2006313486B2 (sr)
BR (1)	BRPI0618284A2 (sr)
CA (1)	CA2629339C (sr)
CR (1)	CR9966A (sr)
DE (1)	DE602006007728D1 (sr)
DK (1)	DK1948661T3 (sr)
DO (1)	DOP2006000248A (sr)
EA (1)	EA200800920A1 (sr)
EC (1)	ECSP088441A (sr)
ES (1)	ES2326919T3 (sr)
IL (1)	IL190456A (sr)
MA (1)	MA29943B1 (sr)
NL (1)	NL2000291C2 (sr)
NO (1)	NO20082593L (sr)
PE (1)	PE20070764A1 (sr)
RS (1)	RS20080197A (sr)
TN (1)	TNSN08209A1 (sr)
TW (1)	TW200738723A (sr)
UY (1)	UY29909A1 (sr)
WO (1)	WO2007054778A1 (sr)
ZA (1)	ZA200803173B (sr)

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JP2011529918A (ja) *	2008-08-01	2011-12-15	バイオクライストファーマシューティカルズ，インコーポレイテッド	Ｊａｋ３阻害剤としてのピペリジン誘導体
WO2010043633A1 (en) *	2008-10-15	2010-04-22	Palau Pharma, S. A.	2h-pyrazolo [4,3-d]pyrimidin-5-amine derivatives as h4 histamine receptor antagonists for the treatment of allergic, immunological and inflammatory diseases
JP2013523809A (ja) *	2010-04-05	2013-06-17	エスケーケミカルズカンパニーリミテッド	Ｐｄｅ５抑制剤を含む皮膚しわ改善用組成物
WO2012118042A1 (ja) *	2011-02-28	2012-09-07	独立行政法人国立循環器病研究センター	悪性腫瘍転移抑制用医薬
AP2013007253A0 (en)	2011-04-21	2013-11-30	Origenis Gmbh	Pyrazolo [4,3-D] pyrimidines useful as kinase inhibitors
WO2014060112A1 (en)	2012-10-19	2014-04-24	Origenis Gmbh	Pyrazolo[4,3-d]pyrimidines as kinase inhibitors
MX2015005004A (es) *	2012-10-23	2015-07-17	Pfizer	Uso de un compuesto de pirazolo[4,3-d]pirimidina tetrasubstituida para tratar la nefropatia diabetica.
TN2017000029A1 (en)	2014-08-12	2018-07-04	Mezzion Pharma Co Ltd	Methods of improving myocardial performance in fontan patients using udenafil compositions
AU2020356193A1 (en)	2019-09-24	2022-05-19	Children's Hospital Of Philadelphia	Methods of improving exercise performance, single ventricular performance, and myocardial performance index (MPI) in single ventricle heart disease, using udenafil compositions

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2006
- 2006-10-27 NL NL2000291A patent/NL2000291C2/nl not_active IP Right Cessation
- 2006-10-31 DE DE602006007728T patent/DE602006007728D1/de active Active
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- 2006-10-31 BR BRPI0618284-4A patent/BRPI0618284A2/pt not_active Application Discontinuation
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- 2006-11-09 US US11/558,306 patent/US20090156618A1/en not_active Abandoned
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- 2008-05-09 MA MA30918A patent/MA29943B1/fr unknown
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Publication number	Publication date
RS20080197A (sr)	2009-05-06
NO20082593L (no)	2008-07-22
ES2326919T3 (es)	2009-10-21
CA2629339A1 (en)	2007-05-18
UY29909A1 (es)	2007-06-29
CN101305007A (zh)	2008-11-12
TNSN08209A1 (fr)	2009-10-30
HK1120803A1 (en)	2009-04-09
ZA200803173B (en)	2009-01-28
ECSP088441A (es)	2008-06-30
KR101012592B1 (ko)	2011-02-07
EA200800920A1 (ru)	2008-10-30
IL190456A (en)	2012-10-31
IL190456A0 (en)	2008-11-03
EP1948661B1 (en)	2009-07-08
BRPI0618284A2 (pt)	2011-08-23
WO2007054778A1 (en)	2007-05-18
KR20080063830A (ko)	2008-07-07
PE20070764A1 (es)	2007-08-13
US20090156618A1 (en)	2009-06-18
DOP2006000248A (es)	2007-10-15
JP4208959B1 (ja)	2009-01-14
US20110059993A1 (en)	2011-03-10
AU2006313486A1 (en)	2007-05-18
CA2629339C (en)	2010-07-27
AU2006313486B2 (en)	2011-10-27
MA29943B1 (fr)	2008-11-03
NL2000291A1 (nl)	2007-05-11
DK1948661T3 (da)	2009-09-07
US8518956B2 (en)	2013-08-27
EP1948661A1 (en)	2008-07-30
AR057885A1 (es)	2007-12-26
JP2009519215A (ja)	2009-05-14
NL2000291C2 (nl)	2009-02-17
ATE435865T1 (de)	2009-07-15
DE602006007728D1 (de)	2009-08-20
CN101305007B (zh)	2011-07-20
TW200738723A (en)	2007-10-16
CR9966A (es)	2008-06-16

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