AP2008004437A0 - Pyrazolo Ä4,3-DÜ pyrimidin-5-yl) derivative used as PDE5 inhibitors - Google Patents

Pyrazolo Ä4,3-DÜ pyrimidin-5-yl) derivative used as PDE5 inhibitors

Info

Publication number: AP2008004437A0
Authority: AP; ARIPO
Prior art keywords: pyrazolo; pyrimidin; derivative used; pde5 inhibitors; pde5
Prior art date: 2005-11-10

Application number

AP2008004437A

Other languages

English (en)

Inventor

Michael Brent Tollefson

Original Assignee

Pfizer Prod Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2005-11-10

Filing date

2006-10-31

Publication date

2008-04-30

2006-10-31 Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc

2008-04-30 Publication of AP2008004437A0 publication Critical patent/AP2008004437A0/xx

Links

229940123333 Phosphodiesterase 5 inhibitor Drugs 0.000 title 1
239000002590 phosphodiesterase V inhibitor Substances 0.000 title 1
125000004528 pyrimidin-5-yl group Chemical group N1=CN=CC(=C1)* 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Diabetes (AREA)
Cardiology (AREA)
Endocrinology (AREA)
Heart & Thoracic Surgery (AREA)
Physical Education & Sports Medicine (AREA)
Pain & Pain Management (AREA)
Hematology (AREA)
Urology & Nephrology (AREA)
Reproductive Health (AREA)
Ophthalmology & Optometry (AREA)
Orthopedic Medicine & Surgery (AREA)
Dermatology (AREA)
Obesity (AREA)
Psychiatry (AREA)
Gynecology & Obstetrics (AREA)
Addiction (AREA)
Psychology (AREA)
Hospice & Palliative Care (AREA)
Vascular Medicine (AREA)
Pregnancy & Childbirth (AREA)
Rheumatology (AREA)
Child & Adolescent Psychology (AREA)

AP2008004437A 2005-11-10 2006-10-31 Pyrazolo Ä4,3-DÜ pyrimidin-5-yl) derivative used as PDE5 inhibitors AP2008004437A0 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US73532005P	2005-11-10	2005-11-10
PCT/IB2006/003132 WO2007054778A1 (en)	2005-11-10	2006-10-31	Pyrazolo[4,3-d]pyrimidin-5-yl)derivative used as pde5 inhibitors

Publications (1)

Publication Number	Publication Date
AP2008004437A0 true AP2008004437A0 (en)	2008-04-30

Family

ID=37685872

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AP2008004437A AP2008004437A0 (en)	2005-11-10	2006-10-31	Pyrazolo Ä4,3-DÜ pyrimidin-5-yl) derivative used as PDE5 inhibitors

Country Status (29)

Country	Link
US (2)	US20090156618A1 (sr)
EP (1)	EP1948661B1 (sr)
JP (1)	JP4208959B1 (sr)
KR (1)	KR101012592B1 (sr)
CN (1)	CN101305007B (sr)
AP (1)	AP2008004437A0 (sr)
AR (1)	AR057885A1 (sr)
AT (1)	ATE435865T1 (sr)
AU (1)	AU2006313486B2 (sr)
BR (1)	BRPI0618284A2 (sr)
CA (1)	CA2629339C (sr)
CR (1)	CR9966A (sr)
DE (1)	DE602006007728D1 (sr)
DK (1)	DK1948661T3 (sr)
DO (1)	DOP2006000248A (sr)
EA (1)	EA200800920A1 (sr)
EC (1)	ECSP088441A (sr)
ES (1)	ES2326919T3 (sr)
IL (1)	IL190456A (sr)
MA (1)	MA29943B1 (sr)
NL (1)	NL2000291C2 (sr)
NO (1)	NO20082593L (sr)
PE (1)	PE20070764A1 (sr)
RS (1)	RS20080197A (sr)
TN (1)	TNSN08209A1 (sr)
TW (1)	TW200738723A (sr)
UY (1)	UY29909A1 (sr)
WO (1)	WO2007054778A1 (sr)
ZA (1)	ZA200803173B (sr)

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RU2011105768A (ru) *	2008-08-01	2012-09-10	Биокрист Фармасьютикалз, Инк. (Us)	Производные пиперидина в качестве ингибиторов jakз
WO2010043633A1 (en) *	2008-10-15	2010-04-22	Palau Pharma, S. A.	2h-pyrazolo [4,3-d]pyrimidin-5-amine derivatives as h4 histamine receptor antagonists for the treatment of allergic, immunological and inflammatory diseases
EP2556820A4 (en) *	2010-04-05	2015-01-21	Sk Chemicals Co Ltd	COMPOSITION CONTAINING PDE5 INHIBITOR FOR MITIGATION OF SKIN WRINKLES
EP3189835B1 (en) *	2011-02-28	2018-07-25	National Cerebral and Cardiovascular Center	Medical agent for suppressing malignant tumor metastasis
AU2012244550C1 (en)	2011-04-21	2017-06-22	Origenis Gmbh	Pyrazolo [4, 3-d] pyrimidines useful as kinase inhibitors
WO2014060112A1 (en)	2012-10-19	2014-04-24	Origenis Gmbh	Pyrazolo[4,3-d]pyrimidines as kinase inhibitors
CA2888160A1 (en) *	2012-10-23	2014-05-01	Pfizer Inc.	Use of a tetrasubstituted pyrazolo[4,3-d]pyrimidine compound for treating diabetic nephropathy
MX390977B (es)	2014-08-12	2025-03-21	Mezzion Pharma Co Ltd	Metodos para mejorar el rendimiento miocardico en pacientes con cirugia de fontan que utilizan composiciones de udenafilo
MX2022003593A (es)	2019-09-24	2022-09-19	Mezzion Pharma Co Ltd	Métodos para mejorar el rendimiento del ejercicio, el rendimiento ventricular único y el índice de rendimiento del miocardio (mpi) en la enfermedad cardiaca del ventrículo único, utilizando composiciones de udenafil.

Family Cites Families (17)

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2006
- 2006-10-27 NL NL2000291A patent/NL2000291C2/nl not_active IP Right Cessation
- 2006-10-31 KR KR1020087011230A patent/KR101012592B1/ko not_active Expired - Fee Related
- 2006-10-31 JP JP2008539522A patent/JP4208959B1/ja not_active Expired - Fee Related
- 2006-10-31 BR BRPI0618284-4A patent/BRPI0618284A2/pt not_active Application Discontinuation
- 2006-10-31 DK DK06809195T patent/DK1948661T3/da active
- 2006-10-31 AT AT06809195T patent/ATE435865T1/de not_active IP Right Cessation
- 2006-10-31 RS RSP-2008/0197A patent/RS20080197A/sr unknown
- 2006-10-31 CA CA2629339A patent/CA2629339C/en not_active Expired - Fee Related
- 2006-10-31 EA EA200800920A patent/EA200800920A1/ru unknown
- 2006-10-31 ES ES06809195T patent/ES2326919T3/es active Active
- 2006-10-31 WO PCT/IB2006/003132 patent/WO2007054778A1/en not_active Ceased
- 2006-10-31 DE DE602006007728T patent/DE602006007728D1/de active Active
- 2006-10-31 CN CN2006800416985A patent/CN101305007B/zh not_active Expired - Fee Related
- 2006-10-31 EP EP06809195A patent/EP1948661B1/en active Active
- 2006-10-31 AP AP2008004437A patent/AP2008004437A0/xx unknown
- 2006-10-31 AU AU2006313486A patent/AU2006313486B2/en not_active Ceased
- 2006-11-07 PE PE2006001379A patent/PE20070764A1/es not_active Application Discontinuation
- 2006-11-08 AR ARP060104894A patent/AR057885A1/es unknown
- 2006-11-09 TW TW095141515A patent/TW200738723A/zh unknown
- 2006-11-09 US US11/558,306 patent/US20090156618A1/en not_active Abandoned
- 2006-11-09 DO DO2006P000248A patent/DOP2006000248A/es unknown
- 2006-11-09 UY UY29909A patent/UY29909A1/es not_active Application Discontinuation
2008
- 2008-03-26 IL IL190456A patent/IL190456A/en not_active IP Right Cessation
- 2008-04-10 ZA ZA200803173A patent/ZA200803173B/xx unknown
- 2008-05-08 EC EC2008008441A patent/ECSP088441A/es unknown
- 2008-05-09 CR CR9966A patent/CR9966A/es not_active Application Discontinuation
- 2008-05-09 TN TNP2008000209A patent/TNSN08209A1/fr unknown
- 2008-05-09 MA MA30918A patent/MA29943B1/fr unknown
- 2008-06-10 NO NO20082593A patent/NO20082593L/no not_active Application Discontinuation
2010
- 2010-11-17 US US12/948,387 patent/US8518956B2/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
CN101305007A (zh)	2008-11-12
NO20082593L (no)	2008-07-22
KR20080063830A (ko)	2008-07-07
EP1948661A1 (en)	2008-07-30
EP1948661B1 (en)	2009-07-08
US20090156618A1 (en)	2009-06-18
AU2006313486A1 (en)	2007-05-18
KR101012592B1 (ko)	2011-02-07
TNSN08209A1 (fr)	2009-10-30
AU2006313486B2 (en)	2011-10-27
HK1120803A1 (en)	2009-04-09
US20110059993A1 (en)	2011-03-10
DE602006007728D1 (de)	2009-08-20
ATE435865T1 (de)	2009-07-15
CN101305007B (zh)	2011-07-20
DOP2006000248A (es)	2007-10-15
IL190456A0 (en)	2008-11-03
RS20080197A (sr)	2009-05-06
NL2000291C2 (nl)	2009-02-17
JP2009519215A (ja)	2009-05-14
UY29909A1 (es)	2007-06-29
CA2629339A1 (en)	2007-05-18
DK1948661T3 (da)	2009-09-07
US8518956B2 (en)	2013-08-27
TW200738723A (en)	2007-10-16
IL190456A (en)	2012-10-31
BRPI0618284A2 (pt)	2011-08-23
PE20070764A1 (es)	2007-08-13
EA200800920A1 (ru)	2008-10-30
CA2629339C (en)	2010-07-27
NL2000291A1 (nl)	2007-05-11
JP4208959B1 (ja)	2009-01-14
CR9966A (es)	2008-06-16
ES2326919T3 (es)	2009-10-21
WO2007054778A1 (en)	2007-05-18
AR057885A1 (es)	2007-12-26
MA29943B1 (fr)	2008-11-03
ZA200803173B (en)	2009-01-28
ECSP088441A (es)	2008-06-30

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