AR072145A1 - Composiciones de uso oral y usos de las mismas que comprenden antibacterianos como el triclosan - Google Patents
Composiciones de uso oral y usos de las mismas que comprenden antibacterianos como el triclosanInfo
- Publication number
- AR072145A1 AR072145A1 ARP090102163A ARP090102163A AR072145A1 AR 072145 A1 AR072145 A1 AR 072145A1 AR P090102163 A ARP090102163 A AR P090102163A AR P090102163 A ARP090102163 A AR P090102163A AR 072145 A1 AR072145 A1 AR 072145A1
- Authority
- AR
- Argentina
- Prior art keywords
- composition
- decrease
- fluoride
- glycol
- inhibit
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 12
- XEFQLINVKFYRCS-UHFFFAOYSA-N Triclosan Chemical compound OC1=CC(Cl)=CC=C1OC1=CC=C(Cl)C=C1Cl XEFQLINVKFYRCS-UHFFFAOYSA-N 0.000 title 1
- 229940088710 antibiotic agent Drugs 0.000 title 1
- 229960003500 triclosan Drugs 0.000 title 1
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 abstract 5
- 230000002209 hydrophobic effect Effects 0.000 abstract 4
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 abstract 3
- MTHSVFCYNBDYFN-UHFFFAOYSA-N diethylene glycol Chemical compound OCCOCCO MTHSVFCYNBDYFN-UHFFFAOYSA-N 0.000 abstract 3
- 239000000839 emulsion Substances 0.000 abstract 3
- -1 fluoride ions Chemical class 0.000 abstract 3
- 239000003752 hydrotrope Substances 0.000 abstract 3
- 210000000214 mouth Anatomy 0.000 abstract 3
- QUCDWLYKDRVKMI-UHFFFAOYSA-M sodium;3,4-dimethylbenzenesulfonate Chemical compound [Na+].CC1=CC=C(S([O-])(=O)=O)C=C1C QUCDWLYKDRVKMI-UHFFFAOYSA-M 0.000 abstract 3
- PUPZLCDOIYMWBV-UHFFFAOYSA-N (+/-)-1,3-Butanediol Chemical compound CC(O)CCO PUPZLCDOIYMWBV-UHFFFAOYSA-N 0.000 abstract 2
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 abstract 2
- MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 abstract 2
- INVGWHRKADIJHF-UHFFFAOYSA-N Sanguinarin Chemical compound C1=C2OCOC2=CC2=C3[N+](C)=CC4=C(OCO5)C5=CC=C4C3=CC=C21 INVGWHRKADIJHF-UHFFFAOYSA-N 0.000 abstract 2
- 230000002421 anti-septic effect Effects 0.000 abstract 2
- 229940064004 antiseptic throat preparations Drugs 0.000 abstract 2
- 230000015572 biosynthetic process Effects 0.000 abstract 2
- OSWPMRLSEDHDFF-UHFFFAOYSA-N methyl salicylate Chemical compound COC(=O)C1=CC=CC=C1O OSWPMRLSEDHDFF-UHFFFAOYSA-N 0.000 abstract 2
- 229960001245 olaflur Drugs 0.000 abstract 2
- ZVVSSOQAYNYNPP-UHFFFAOYSA-N olaflur Chemical compound F.F.CCCCCCCCCCCCCCCCCCN(CCO)CCCN(CCO)CCO ZVVSSOQAYNYNPP-UHFFFAOYSA-N 0.000 abstract 2
- NROKBHXJSPEDAR-UHFFFAOYSA-M potassium fluoride Chemical compound [F-].[K+] NROKBHXJSPEDAR-UHFFFAOYSA-M 0.000 abstract 2
- PUZPDOWCWNUUKD-UHFFFAOYSA-M sodium fluoride Chemical compound [F-].[Na+] PUZPDOWCWNUUKD-UHFFFAOYSA-M 0.000 abstract 2
- MGSRCZKZVOBKFT-UHFFFAOYSA-N thymol Chemical compound CC(C)C1=CC=C(C)C=C1O MGSRCZKZVOBKFT-UHFFFAOYSA-N 0.000 abstract 2
- 239000000341 volatile oil Substances 0.000 abstract 2
- NOOLISFMXDJSKH-UTLUCORTSA-N (+)-Neomenthol Chemical compound CC(C)[C@@H]1CC[C@@H](C)C[C@@H]1O NOOLISFMXDJSKH-UTLUCORTSA-N 0.000 abstract 1
- DTOUUUZOYKYHEP-UHFFFAOYSA-N 1,3-bis(2-ethylhexyl)-5-methyl-1,3-diazinan-5-amine Chemical compound CCCCC(CC)CN1CN(CC(CC)CCCC)CC(C)(N)C1 DTOUUUZOYKYHEP-UHFFFAOYSA-N 0.000 abstract 1
- 229940058015 1,3-butylene glycol Drugs 0.000 abstract 1
- WEEGYLXZBRQIMU-UHFFFAOYSA-N 1,8-cineole Natural products C1CC2CCC1(C)OC2(C)C WEEGYLXZBRQIMU-UHFFFAOYSA-N 0.000 abstract 1
- CPKVUHPKYQGHMW-UHFFFAOYSA-N 1-ethenylpyrrolidin-2-one;molecular iodine Chemical compound II.C=CN1CCCC1=O CPKVUHPKYQGHMW-UHFFFAOYSA-N 0.000 abstract 1
- LCZVSXRMYJUNFX-UHFFFAOYSA-N 2-[2-(2-hydroxypropoxy)propoxy]propan-1-ol Chemical compound CC(O)COC(C)COC(C)CO LCZVSXRMYJUNFX-UHFFFAOYSA-N 0.000 abstract 1
- UOWIFEANNONTKY-UHFFFAOYSA-N 2-hydroxy-5-octanoyl-n-[3-(trifluoromethyl)phenyl]benzamide Chemical compound CCCCCCCC(=O)C1=CC=C(O)C(C(=O)NC=2C=C(C=CC=2)C(F)(F)F)=C1 UOWIFEANNONTKY-UHFFFAOYSA-N 0.000 abstract 1
- XGRSAFKZAGGXJV-UHFFFAOYSA-N 3-azaniumyl-3-cyclohexylpropanoate Chemical compound OC(=O)CC(N)C1CCCCC1 XGRSAFKZAGGXJV-UHFFFAOYSA-N 0.000 abstract 1
- HIQIXEFWDLTDED-UHFFFAOYSA-N 4-hydroxy-1-piperidin-4-ylpyrrolidin-2-one Chemical group O=C1CC(O)CN1C1CCNCC1 HIQIXEFWDLTDED-UHFFFAOYSA-N 0.000 abstract 1
- DDFHBQSCUXNBSA-UHFFFAOYSA-N 5-(5-carboxythiophen-2-yl)thiophene-2-carboxylic acid Chemical compound S1C(C(=O)O)=CC=C1C1=CC=C(C(O)=O)S1 DDFHBQSCUXNBSA-UHFFFAOYSA-N 0.000 abstract 1
- 206010006326 Breath odour Diseases 0.000 abstract 1
- GHXZTYHSJHQHIJ-UHFFFAOYSA-N Chlorhexidine Chemical compound C=1C=C(Cl)C=CC=1NC(N)=NC(N)=NCCCCCCN=C(N)N=C(N)NC1=CC=C(Cl)C=C1 GHXZTYHSJHQHIJ-UHFFFAOYSA-N 0.000 abstract 1
- FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 abstract 1
- FBPFZTCFMRRESA-JGWLITMVSA-N D-glucitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-JGWLITMVSA-N 0.000 abstract 1
- NOOLISFMXDJSKH-UHFFFAOYSA-N DL-menthol Natural products CC(C)C1CCC(C)CC1O NOOLISFMXDJSKH-UHFFFAOYSA-N 0.000 abstract 1
- FCEXWTOTHXCQCQ-UHFFFAOYSA-N Ethoxydihydrosanguinarine Natural products C12=CC=C3OCOC3=C2C(OCC)N(C)C(C2=C3)=C1C=CC2=CC1=C3OCO1 FCEXWTOTHXCQCQ-UHFFFAOYSA-N 0.000 abstract 1
- WEEGYLXZBRQIMU-WAAGHKOSSA-N Eucalyptol Chemical compound C1C[C@H]2CC[C@]1(C)OC2(C)C WEEGYLXZBRQIMU-WAAGHKOSSA-N 0.000 abstract 1
- 208000032139 Halitosis Diseases 0.000 abstract 1
- 206010020751 Hypersensitivity Diseases 0.000 abstract 1
- 229920000153 Povidone-iodine Polymers 0.000 abstract 1
- 241000241413 Propolis Species 0.000 abstract 1
- 239000005844 Thymol Substances 0.000 abstract 1
- TVXBFESIOXBWNM-UHFFFAOYSA-N Xylitol Natural products OCCC(O)C(O)C(O)CCO TVXBFESIOXBWNM-UHFFFAOYSA-N 0.000 abstract 1
- 229950010221 alexidine Drugs 0.000 abstract 1
- LFVVNPBBFUSSHL-UHFFFAOYSA-N alexidine Chemical compound CCCCC(CC)CNC(=N)NC(=N)NCCCCCCNC(=N)NC(=N)NCC(CC)CCCC LFVVNPBBFUSSHL-UHFFFAOYSA-N 0.000 abstract 1
- 208000026935 allergic disease Diseases 0.000 abstract 1
- 239000003242 anti bacterial agent Substances 0.000 abstract 1
- 235000019437 butane-1,3-diol Nutrition 0.000 abstract 1
- WERYXYBDKMZEQL-UHFFFAOYSA-N butane-1,4-diol Chemical compound OCCCCO WERYXYBDKMZEQL-UHFFFAOYSA-N 0.000 abstract 1
- 239000003093 cationic surfactant Substances 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 229960003260 chlorhexidine Drugs 0.000 abstract 1
- 229960005233 cineole Drugs 0.000 abstract 1
- 229920001577 copolymer Polymers 0.000 abstract 1
- 229960003854 delmopinol Drugs 0.000 abstract 1
- QSFOWAYMMZCQNF-UHFFFAOYSA-N delmopinol Chemical compound CCCC(CCC)CCCC1COCCN1CCO QSFOWAYMMZCQNF-UHFFFAOYSA-N 0.000 abstract 1
- 238000005115 demineralization Methods 0.000 abstract 1
- 230000002328 demineralizing effect Effects 0.000 abstract 1
- 208000002925 dental caries Diseases 0.000 abstract 1
- USIUVYZYUHIAEV-UHFFFAOYSA-N diphenyl ether Chemical class C=1C=CC=CC=1OC1=CC=CC=C1 USIUVYZYUHIAEV-UHFFFAOYSA-N 0.000 abstract 1
- SZXQTJUDPRGNJN-UHFFFAOYSA-N dipropylene glycol Chemical compound OCCCOCCCO SZXQTJUDPRGNJN-UHFFFAOYSA-N 0.000 abstract 1
- 239000008157 edible vegetable oil Substances 0.000 abstract 1
- 229940091249 fluoride supplement Drugs 0.000 abstract 1
- 208000007565 gingivitis Diseases 0.000 abstract 1
- 235000011187 glycerol Nutrition 0.000 abstract 1
- 239000012676 herbal extract Substances 0.000 abstract 1
- 229960004867 hexetidine Drugs 0.000 abstract 1
- WGCNASOHLSPBMP-UHFFFAOYSA-N hydroxyacetaldehyde Natural products OCC=O WGCNASOHLSPBMP-UHFFFAOYSA-N 0.000 abstract 1
- 230000009610 hypersensitivity Effects 0.000 abstract 1
- FPYJFEHAWHCUMM-UHFFFAOYSA-N maleic anhydride Chemical compound O=C1OC(=O)C=C1 FPYJFEHAWHCUMM-UHFFFAOYSA-N 0.000 abstract 1
- 229940041616 menthol Drugs 0.000 abstract 1
- HEBKCHPVOIAQTA-UHFFFAOYSA-N meso ribitol Natural products OCC(O)C(O)C(O)CO HEBKCHPVOIAQTA-UHFFFAOYSA-N 0.000 abstract 1
- 229910021645 metal ion Inorganic materials 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 229960001047 methyl salicylate Drugs 0.000 abstract 1
- 230000000813 microbial effect Effects 0.000 abstract 1
- 239000002480 mineral oil Substances 0.000 abstract 1
- 235000010446 mineral oil Nutrition 0.000 abstract 1
- 239000002324 mouth wash Substances 0.000 abstract 1
- 229940051866 mouthwash Drugs 0.000 abstract 1
- 229960001774 octenidine Drugs 0.000 abstract 1
- SMGTYJPMKXNQFY-UHFFFAOYSA-N octenidine dihydrochloride Chemical compound Cl.Cl.C1=CC(=NCCCCCCCC)C=CN1CCCCCCCCCCN1C=CC(=NCCCCCCCC)C=C1 SMGTYJPMKXNQFY-UHFFFAOYSA-N 0.000 abstract 1
- 239000003921 oil Substances 0.000 abstract 1
- 230000001706 oxygenating effect Effects 0.000 abstract 1
- ISWSIDIOOBJBQZ-UHFFFAOYSA-N phenol group Chemical group C1(=CC=CC=C1)O ISWSIDIOOBJBQZ-UHFFFAOYSA-N 0.000 abstract 1
- 230000007406 plaque accumulation Effects 0.000 abstract 1
- 229920000151 polyglycol Polymers 0.000 abstract 1
- 239000010695 polyglycol Substances 0.000 abstract 1
- 229920001289 polyvinyl ether Polymers 0.000 abstract 1
- 239000011698 potassium fluoride Substances 0.000 abstract 1
- 235000003270 potassium fluoride Nutrition 0.000 abstract 1
- 229960001621 povidone-iodine Drugs 0.000 abstract 1
- 229940069949 propolis Drugs 0.000 abstract 1
- 229940092258 rosemary extract Drugs 0.000 abstract 1
- 235000020748 rosemary extract Nutrition 0.000 abstract 1
- 239000001233 rosmarinus officinalis l. extract Substances 0.000 abstract 1
- 229940084560 sanguinarine Drugs 0.000 abstract 1
- YZRQUTZNTDAYPJ-UHFFFAOYSA-N sanguinarine pseudobase Natural products C1=C2OCOC2=CC2=C3N(C)C(O)C4=C(OCO5)C5=CC=C4C3=CC=C21 YZRQUTZNTDAYPJ-UHFFFAOYSA-N 0.000 abstract 1
- 239000011775 sodium fluoride Substances 0.000 abstract 1
- 235000013024 sodium fluoride Nutrition 0.000 abstract 1
- 229960004711 sodium monofluorophosphate Drugs 0.000 abstract 1
- MWNQXXOSWHCCOZ-UHFFFAOYSA-L sodium;oxido carbonate Chemical compound [Na+].[O-]OC([O-])=O MWNQXXOSWHCCOZ-UHFFFAOYSA-L 0.000 abstract 1
- 239000000600 sorbitol Substances 0.000 abstract 1
- 229960002799 stannous fluoride Drugs 0.000 abstract 1
- ANOBYBYXJXCGBS-UHFFFAOYSA-L stannous fluoride Chemical group F[Sn]F ANOBYBYXJXCGBS-UHFFFAOYSA-L 0.000 abstract 1
- 150000005846 sugar alcohols Polymers 0.000 abstract 1
- 229960000790 thymol Drugs 0.000 abstract 1
- WGIWBXUNRXCYRA-UHFFFAOYSA-H trizinc;2-hydroxypropane-1,2,3-tricarboxylate Chemical compound [Zn+2].[Zn+2].[Zn+2].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O.[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O WGIWBXUNRXCYRA-UHFFFAOYSA-H 0.000 abstract 1
- 239000000811 xylitol Substances 0.000 abstract 1
- 235000010447 xylitol Nutrition 0.000 abstract 1
- HEBKCHPVOIAQTA-SCDXWVJYSA-N xylitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)CO HEBKCHPVOIAQTA-SCDXWVJYSA-N 0.000 abstract 1
- 229960002675 xylitol Drugs 0.000 abstract 1
- 150000003751 zinc Chemical class 0.000 abstract 1
- 239000011746 zinc citrate Substances 0.000 abstract 1
- 235000006076 zinc citrate Nutrition 0.000 abstract 1
- 229940068475 zinc citrate Drugs 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/03—Liquid compositions with two or more distinct layers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/04—Dispersions; Emulsions
- A61K8/06—Emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/20—Halogens; Compounds thereof
- A61K8/21—Fluorides; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Chemical & Material Sciences (AREA)
- Emergency Medicine (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Inorganic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Communicable Diseases (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Dispersion Chemistry (AREA)
- Cosmetics (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Plant Substances (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Composicion bif sica para el enjuague bucal que incluye una fase hidrof¡lica, una fase hidrofobica y un hidrotropo. Las fases hidrof¡lica e hidrofobica permanecen separadas y forman una emulsion temporal al ser combinadas. La emulsion se revierte espont neamente a las dos fases originales luego de ser dejada en reposo, sin formarse una emulsion. Reivindicacion 2: La composicion de la reivindicacion 1, caracterizada porque el componente hidrotropo incluye un poliglicol, un alcohol polih¡drico o una mezcla de los anteriores. Reivindicacion 3: La composicion de la reivindicacion 1 o 2, caracterizada porque el componente hidrotropo incluye etilenglicol, propilenglicol, glicerina, dietilenglicol, dipropilenglicol, tripropilenglicol, nexilenglicol, 1,3-butilenglicol, 1,4-butilenglicol, 1,2,6-hexanotriol, sorbitol, xilitol o una combinacion de los anteriores. Reivindicacion 6: La composicion de cualquiera de las reivindicaciones que anteceden, caracterizada porque la fase hidrofobica incluye un aceite que es seleccionado a partir de miristato de isopropilo, aceite mineral, un aceite comestible y sus combinaciones. Reivindicacion 8: La composicion de cualquiera de las reivindicaciones que anteceden, caracterizada porque incluye un agente antibacteriano que es seleccionado a partir de un eter difen¡lico halogenado (triclos n), extractos de hierbas o aceites esenciales (por ejemplo, extracto de romero, timol, mentol, eucaliptol, salicilato de metilo), antisepticos a base de bisguanida (por ejemplo, clorhexidina, alexidina o octenidina), antisepticos fenolicos, hexetidina, povidona yodada, delmopinol, salifluor, iones met licos (por ejemplo, sales de zinc, por ejemplo, citrato de zinc), sanguinarina, propolis y agentes oxigenantes (por ejemplo, peroxido de hidrogeno, peroxiborato o peroxicarbonato de sodio amortiguado). Reivindicacion 11: La composicion de cualquiera de las reivindicaciones que anteceden, caracterizada porque la fase hidrofobica incluye un aceite esencial. Reivindicacion 12: La composicion de cualquiera de las reivindicaciones que anteceden, caracterizada porque la fase hidrof¡lica incluye un copol¡mero de eter polivinilmet¡lico/anh¡drido maleico. Reivindicacion 13: La composicion de cualquiera de las reivindicaciones que anteceden, caracterizada porque la fase hidrof¡lica incluye una fuente de iones fluoruro que es seleccionada a partir de fluoruro estanoso, fluoruro de sodio, fluoruro de potasio, monofluorofosfato de sodio, fluorosilicato de sodio, fluorosilicato de amonio, fluoruro de amina, fluoruro de amina, fluoruro de amonio y sus combinaciones. Reivindicacion 21: La composicion de cualquiera de las reivindicaciones que anteceden, caracterizada porque est esencialmente exenta de un surfactante cationico. Reivindicacion 22: Un metodo para mejorar la salud oral, caracterizado porque consiste en aplicarle una cantidad efectiva de la composicion de uso oral de cualquiera de las reivindicaciones 1-21 a la cavidad bucal de un sujeto que as¡ lo requiere, a los fines de: 1) disminuir o inhibir la formacion de caries dentales, 2) disminuir o inhibir la desmineralizacion y promover la remineralizacion de los dientes, 3) disminuir la hipersensibilidad de los dientes, 4) disminuir o inhibir la gingivitis, 5) inhibir la formacion de biopel¡culas microbianas en la cavidad bucal, 6) tratar y/o disminuir la acumulacion de placa, y/o 7) limpiar los dientes y/o la cavidad bucal y/o 8) tratar y/o disminuir la halitosis.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US12/138,647 US9724278B2 (en) | 2008-06-13 | 2008-06-13 | Oral compositions and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR072145A1 true AR072145A1 (es) | 2010-08-11 |
Family
ID=41414992
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP090102163A AR072145A1 (es) | 2008-06-13 | 2009-06-12 | Composiciones de uso oral y usos de las mismas que comprenden antibacterianos como el triclosan |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US9724278B2 (es) |
| EP (1) | EP2293849B1 (es) |
| JP (1) | JP2011526245A (es) |
| CN (2) | CN105581925A (es) |
| AR (1) | AR072145A1 (es) |
| AU (1) | AU2009257250B2 (es) |
| BR (1) | BRPI0915025B1 (es) |
| CA (1) | CA2726560C (es) |
| CO (1) | CO6341582A2 (es) |
| MX (1) | MX2010013440A (es) |
| MY (1) | MY157314A (es) |
| RU (1) | RU2483709C2 (es) |
| TW (1) | TWI432215B (es) |
| WO (1) | WO2009152507A2 (es) |
| ZA (1) | ZA201008887B (es) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102009049504A1 (de) * | 2009-10-15 | 2011-04-21 | Schülke & Mayr GmbH | Wund- und Schleimhautantiseptikum auf der Basis von Bispyridiniumalkanen |
| JP5723001B2 (ja) | 2010-06-23 | 2015-05-27 | コルゲート・パーモリブ・カンパニーＣｏｌｇａｔｅ−Ｐａｌｍｏｌｉｖｅ Ｃｏｍｐａｎｙ | 治療用口腔用組成物 |
| US9622962B2 (en) | 2010-11-12 | 2017-04-18 | Colgate-Palmolive Company | Oral care product and methods of use and manufacture thereof |
| WO2012087279A1 (en) | 2010-12-20 | 2012-06-28 | Colgate-Palmolive Company | Gelatin encapsulated oral care composition containing dental occlusion actives, hydrophobic viscosity modifier and oil carrier |
| US9289369B2 (en) | 2010-12-20 | 2016-03-22 | Colgate-Palmolive Company | Non-aqueous oral care composition containing dental occlusion actives |
| JP5854038B2 (ja) * | 2011-03-11 | 2016-02-09 | ライオン株式会社 | ２層分離型液体口腔用組成物 |
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-
2008
- 2008-06-13 US US12/138,647 patent/US9724278B2/en active Active
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2009
- 2009-06-12 TW TW098119627A patent/TWI432215B/zh not_active IP Right Cessation
- 2009-06-12 AR ARP090102163A patent/AR072145A1/es unknown
- 2009-06-15 RU RU2011100783/15A patent/RU2483709C2/ru not_active IP Right Cessation
- 2009-06-15 AU AU2009257250A patent/AU2009257250B2/en active Active
- 2009-06-15 MY MYPI2010005863A patent/MY157314A/en unknown
- 2009-06-15 BR BRPI0915025A patent/BRPI0915025B1/pt not_active IP Right Cessation
- 2009-06-15 WO PCT/US2009/047383 patent/WO2009152507A2/en not_active Ceased
- 2009-06-15 CN CN201511020706.5A patent/CN105581925A/zh active Pending
- 2009-06-15 EP EP09763794.6A patent/EP2293849B1/en not_active Not-in-force
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- 2010-12-09 ZA ZA2010/08887A patent/ZA201008887B/en unknown
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| CA2726560C (en) | 2015-01-06 |
| CN102281922A (zh) | 2011-12-14 |
| WO2009152507A3 (en) | 2011-08-11 |
| EP2293849B1 (en) | 2017-01-04 |
| CA2726560A1 (en) | 2009-12-17 |
| JP2011526245A (ja) | 2011-10-06 |
| EP2293849A2 (en) | 2011-03-16 |
| US9724278B2 (en) | 2017-08-08 |
| CO6341582A2 (es) | 2011-11-21 |
| TW201010735A (en) | 2010-03-16 |
| WO2009152507A2 (en) | 2009-12-17 |
| AU2009257250A1 (en) | 2009-12-17 |
| RU2483709C2 (ru) | 2013-06-10 |
| BRPI0915025A2 (pt) | 2015-10-27 |
| US20090311200A1 (en) | 2009-12-17 |
| MY157314A (en) | 2016-05-31 |
| CN105581925A (zh) | 2016-05-18 |
| TWI432215B (zh) | 2014-04-01 |
| BRPI0915025B1 (pt) | 2016-12-13 |
| AU2009257250B2 (en) | 2012-08-30 |
| MX2010013440A (es) | 2011-03-02 |
| ZA201008887B (en) | 2014-11-26 |
| RU2011100783A (ru) | 2012-07-20 |
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