ATE110963T1 - Mittel zur hemmung der alpha-amylase aktivität. - Google Patents
Mittel zur hemmung der alpha-amylase aktivität.Info
- Publication number
- ATE110963T1 ATE110963T1 AT90107475T AT90107475T ATE110963T1 AT E110963 T1 ATE110963 T1 AT E110963T1 AT 90107475 T AT90107475 T AT 90107475T AT 90107475 T AT90107475 T AT 90107475T AT E110963 T1 ATE110963 T1 AT E110963T1
- Authority
- AT
- Austria
- Prior art keywords
- tea
- agents
- theaflavin
- amylase activity
- inhibiting alpha
- Prior art date
Links
- 244000269722 Thea sinensis Species 0.000 abstract 4
- 235000013616 tea Nutrition 0.000 abstract 3
- XMOCLSLCDHWDHP-IUODEOHRSA-N epi-Gallocatechin Chemical compound C1([C@H]2OC3=CC(O)=CC(O)=C3C[C@H]2O)=CC(O)=C(O)C(O)=C1 XMOCLSLCDHWDHP-IUODEOHRSA-N 0.000 abstract 2
- 229930013915 (+)-catechin Natural products 0.000 abstract 1
- 235000007219 (+)-catechin Nutrition 0.000 abstract 1
- PFTAWBLQPZVEMU-DZGCQCFKSA-N (+)-catechin Chemical compound C1([C@H]2OC3=CC(O)=CC(O)=C3C[C@@H]2O)=CC=C(O)C(O)=C1 PFTAWBLQPZVEMU-DZGCQCFKSA-N 0.000 abstract 1
- PFTAWBLQPZVEMU-ZFWWWQNUSA-N (+)-epicatechin Natural products C1([C@@H]2OC3=CC(O)=CC(O)=C3C[C@@H]2O)=CC=C(O)C(O)=C1 PFTAWBLQPZVEMU-ZFWWWQNUSA-N 0.000 abstract 1
- WMBWREPUVVBILR-WIYYLYMNSA-N (-)-Epigallocatechin-3-o-gallate Chemical compound O([C@@H]1CC2=C(O)C=C(C=C2O[C@@H]1C=1C=C(O)C(O)=C(O)C=1)O)C(=O)C1=CC(O)=C(O)C(O)=C1 WMBWREPUVVBILR-WIYYLYMNSA-N 0.000 abstract 1
- PFTAWBLQPZVEMU-UKRRQHHQSA-N (-)-epicatechin Chemical compound C1([C@H]2OC3=CC(O)=CC(O)=C3C[C@H]2O)=CC=C(O)C(O)=C1 PFTAWBLQPZVEMU-UKRRQHHQSA-N 0.000 abstract 1
- LSHVYAFMTMFKBA-TZIWHRDSSA-N (-)-epicatechin-3-O-gallate Chemical compound O([C@@H]1CC2=C(O)C=C(C=C2O[C@@H]1C=1C=C(O)C(O)=CC=1)O)C(=O)C1=CC(O)=C(O)C(O)=C1 LSHVYAFMTMFKBA-TZIWHRDSSA-N 0.000 abstract 1
- LSHVYAFMTMFKBA-UHFFFAOYSA-N ECG Natural products C=1C=C(O)C(O)=CC=1C1OC2=CC(O)=CC(O)=C2CC1OC(=O)C1=CC(O)=C(O)C(O)=C1 LSHVYAFMTMFKBA-UHFFFAOYSA-N 0.000 abstract 1
- WMBWREPUVVBILR-UHFFFAOYSA-N GCG Natural products C=1C(O)=C(O)C(O)=CC=1C1OC2=CC(O)=CC(O)=C2CC1OC(=O)C1=CC(O)=C(O)C(O)=C1 WMBWREPUVVBILR-UHFFFAOYSA-N 0.000 abstract 1
- IPMYMEWFZKHGAX-UHFFFAOYSA-N Isotheaflavin Natural products OC1CC2=C(O)C=C(O)C=C2OC1C(C1=C2)=CC(O)=C(O)C1=C(O)C(=O)C=C2C1C(O)CC2=C(O)C=C(O)C=C2O1 IPMYMEWFZKHGAX-UHFFFAOYSA-N 0.000 abstract 1
- XMOCLSLCDHWDHP-UHFFFAOYSA-N L-Epigallocatechin Natural products OC1CC2=C(O)C=C(O)C=C2OC1C1=CC(O)=C(O)C(O)=C1 XMOCLSLCDHWDHP-UHFFFAOYSA-N 0.000 abstract 1
- 235000006468 Thea sinensis Nutrition 0.000 abstract 1
- UXRMWRBWCAGDQB-UHFFFAOYSA-N Theaflavin Natural products C1=CC(C2C(CC3=C(O)C=C(O)C=C3O2)O)=C(O)C(=O)C2=C1C(C1OC3=CC(O)=CC(O)=C3CC1O)=CC(O)=C2O UXRMWRBWCAGDQB-UHFFFAOYSA-N 0.000 abstract 1
- 241000700605 Viruses Species 0.000 abstract 1
- KMJPKUVSXFVQGZ-WQLSNUALSA-N [(2r,3r)-5,7-dihydroxy-2-[3,4,5-trihydroxy-6-oxo-1-[(2r,3r)-3,5,7-trihydroxy-3,4-dihydro-2h-chromen-2-yl]benzo[7]annulen-8-yl]-3,4-dihydro-2h-chromen-3-yl] 3,4,5-trihydroxybenzoate Chemical class O([C@@H]1CC2=C(O)C=C(O)C=C2O[C@@H]1C1=CC(=O)C(O)=C2C(O)=C(O)C=C(C2=C1)[C@H]1OC2=CC(O)=CC(O)=C2C[C@H]1O)C(=O)C1=CC(O)=C(O)C(O)=C1 KMJPKUVSXFVQGZ-WQLSNUALSA-N 0.000 abstract 1
- 102000004139 alpha-Amylases Human genes 0.000 abstract 1
- 108090000637 alpha-Amylases Proteins 0.000 abstract 1
- 229940024171 alpha-amylase Drugs 0.000 abstract 1
- 235000020279 black tea Nutrition 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 239000000470 constituent Substances 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- LPTRNLNOHUVQMS-UHFFFAOYSA-N epicatechin Natural products Cc1cc(O)cc2OC(C(O)Cc12)c1ccc(O)c(O)c1 LPTRNLNOHUVQMS-UHFFFAOYSA-N 0.000 abstract 1
- 235000012734 epicatechin Nutrition 0.000 abstract 1
- DZYNKLUGCOSVKS-UHFFFAOYSA-N epigallocatechin Natural products OC1Cc2cc(O)cc(O)c2OC1c3cc(O)c(O)c(O)c3 DZYNKLUGCOSVKS-UHFFFAOYSA-N 0.000 abstract 1
- 229940030275 epigallocatechin gallate Drugs 0.000 abstract 1
- 239000004615 ingredient Substances 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 150000008442 polyphenolic compounds Chemical class 0.000 abstract 1
- 235000013824 polyphenols Nutrition 0.000 abstract 1
- 235000014620 theaflavin Nutrition 0.000 abstract 1
- IPMYMEWFZKHGAX-ZKSIBHASSA-N theaflavin Chemical compound C1=C2C([C@H]3OC4=CC(O)=CC(O)=C4C[C@H]3O)=CC(O)=C(O)C2=C(O)C(=O)C=C1[C@@H]1[C@H](O)CC2=C(O)C=C(O)C=C2O1 IPMYMEWFZKHGAX-ZKSIBHASSA-N 0.000 abstract 1
- 229940026509 theaflavin Drugs 0.000 abstract 1
- FJYGFTHLNNSVPY-BBXLVSEPSA-N theaflavin digallate Chemical compound C1=C([C@@H]2[C@@H](CC3=C(O)C=C(O)C=C3O2)O)C=C(OC(=O)C=2C=C(O)C(O)=C(O)C=2)C(=O)C2=C1C([C@H]1OC3=CC(O)=CC(O)=C3C[C@H]1O)=CC(O)=C2OC(=O)C1=CC(O)=C(O)C(O)=C1 FJYGFTHLNNSVPY-BBXLVSEPSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/82—Theaceae (Tea family), e.g. camellia
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23F—COFFEE; TEA; THEIR SUBSTITUTES; MANUFACTURE, PREPARATION, OR INFUSION THEREOF
- A23F3/00—Tea; Tea substitutes; Preparations thereof
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23F—COFFEE; TEA; THEIR SUBSTITUTES; MANUFACTURE, PREPARATION, OR INFUSION THEREOF
- A23F3/00—Tea; Tea substitutes; Preparations thereof
- A23F3/16—Tea extraction; Tea extracts; Treating tea extract; Making instant tea
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Botany (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Alternative & Traditional Medicine (AREA)
- Biotechnology (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Child & Adolescent Psychology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
- Pyrane Compounds (AREA)
- Tea And Coffee (AREA)
- Fats And Perfumes (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Compounds Of Unknown Constitution (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP1270228A JP3018013B2 (ja) | 1989-10-19 | 1989-10-19 | α―アミラーゼ活性阻害剤 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE110963T1 true ATE110963T1 (de) | 1994-09-15 |
Family
ID=17483335
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT90107475T ATE110963T1 (de) | 1989-10-19 | 1990-04-19 | Mittel zur hemmung der alpha-amylase aktivität. |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP0423419B1 (de) |
| JP (1) | JP3018013B2 (de) |
| KR (1) | KR0178522B1 (de) |
| AT (1) | ATE110963T1 (de) |
| AU (1) | AU628514B2 (de) |
| CA (1) | CA2014971C (de) |
| DE (1) | DE69012268T2 (de) |
Families Citing this family (52)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2727471B2 (ja) * | 1989-09-14 | 1998-03-11 | 三井農林株式会社 | インフルエンザウィルス感染予防剤 |
| JPH04253918A (ja) * | 1991-02-05 | 1992-09-09 | Mitsui Norin Kk | 血糖上昇抑制剤 |
| FR2788438B1 (fr) * | 1999-01-14 | 2003-10-03 | Arkopharma Laboratoires | Composition pour le traitement de l'obesite et procede de traitement esthetique |
| AU2001241078B2 (en) | 2000-03-10 | 2006-02-09 | Kabushiki Kaisha Yakult Honsha | Alpha-amylase activity inhibitors |
| JP2011105763A (ja) * | 2000-06-21 | 2011-06-02 | Kao Corp | Ppar依存的遺伝子転写活性化剤 |
| US6932990B2 (en) | 2000-08-01 | 2005-08-23 | Oryza Oil & Fat Chemical Co., Ltd. | Carbohydrate absorption inhibitor and method for manufacturing the same |
| JP4727790B2 (ja) * | 2000-08-02 | 2011-07-20 | グンゼ株式会社 | 抗肥満剤 |
| EP1333726B1 (de) | 2000-11-17 | 2005-04-06 | Kao Corporation | Verpackte getränke |
| KR20030025200A (ko) * | 2001-09-19 | 2003-03-28 | (주)바이오니아 | 아밀라제의 활성을 억제할 수 있는 옥수수 추출물, 이를함유하는 비만증 또는 당뇨병 치료 또는 예방용 의약적조성물 및 식품 첨가물 그리고 그들의 제조방법 |
| JP3403400B1 (ja) | 2001-09-28 | 2003-05-06 | 花王株式会社 | 容器詰飲料 |
| JP3378577B1 (ja) | 2001-09-28 | 2003-02-17 | 花王株式会社 | 飲 料 |
| US7157493B2 (en) | 2001-11-28 | 2007-01-02 | Nashai Biotech, Llc | Methods of making and using theaflavin, theaflavin-3-gallate, theaflavin-3′-gallate and theaflavin 3,3′-digallate and mixtures thereof |
| JP2005523242A (ja) * | 2001-11-28 | 2005-08-04 | ナシャイ・バイオテック・リミテッド・ライアビリティ・カンパニー | テアフラビン、テアフラビン−3−ガレート、テアフラビン−3’−ガレートおよびテアフラビン3,3’−ジガレートおよびそれらの混合物の製法および使用法 |
| FR2836336B1 (fr) * | 2002-02-26 | 2004-08-27 | Diana Ingredients | Utilisation dans un traitement cosmetique d'une fraction phenolique riche en dihydrochalcones |
| FR2836337B1 (fr) * | 2002-02-28 | 2004-11-19 | Bio Serae Laboratoires | Utilisation des polymeres procyanidoliques a titre d'agents inhibuteurs des alpha-amylases et application dans des compositions a visees dietetiques |
| EP2382876B1 (de) | 2002-10-28 | 2013-08-28 | Kao Corporation | Verfahren zum Reinigen eines festen Konzentrats eines Teeextrakts |
| JP2006508096A (ja) * | 2002-11-07 | 2006-03-09 | ディーエスエム アイピー アセッツ ビー.ブイ. | 没食子酸エピガロカテキンを含む新規な栄養補助組成物 |
| JP4776149B2 (ja) * | 2003-03-28 | 2011-09-21 | クラシエフーズ株式会社 | 糖質吸収抑制剤および食品 |
| US7220444B2 (en) | 2003-09-26 | 2007-05-22 | Kao Corporation | Packaged beverages |
| JP3597857B2 (ja) | 2003-10-31 | 2004-12-08 | 花王株式会社 | 容器詰茶飲料 |
| DE602004028647D1 (de) | 2003-12-02 | 2010-09-23 | Kao Corp | Verpacktes getränk |
| JP3766670B2 (ja) | 2003-12-16 | 2006-04-12 | 花王株式会社 | 容器詰飲料 |
| TWI321039B (en) | 2003-12-18 | 2010-03-01 | Kao Corp | Packaged beverages |
| JP3597859B2 (ja) | 2003-12-22 | 2004-12-08 | 花王株式会社 | 容器詰緑茶飲料及びその製造法 |
| JP2006016367A (ja) * | 2004-07-05 | 2006-01-19 | Suntory Ltd | リパーゼ阻害剤 |
| JP3742096B1 (ja) * | 2005-02-08 | 2006-02-01 | 花王株式会社 | 非茶系容器詰飲料 |
| JP3742094B1 (ja) * | 2004-11-04 | 2006-02-01 | 花王株式会社 | 非茶系容器詰飲料 |
| KR20070026005A (ko) * | 2005-09-01 | 2007-03-08 | 카오카부시키가이샤 | 정제 녹차 추출물의 제조 방법 |
| JP4884003B2 (ja) | 2005-12-27 | 2012-02-22 | 花王株式会社 | 容器詰烏龍茶飲料 |
| WO2007099715A1 (ja) | 2006-03-02 | 2007-09-07 | Kao Corporation | 精製茶抽出物の製造方法 |
| JP4569965B2 (ja) | 2006-04-17 | 2010-10-27 | 花王株式会社 | 精製緑茶抽出物の製造法 |
| JP4562682B2 (ja) | 2006-04-17 | 2010-10-13 | 花王株式会社 | 精製緑茶抽出物の製造法 |
| JP5080835B2 (ja) | 2006-07-04 | 2012-11-21 | 花王株式会社 | 発泡性容器詰飲料 |
| JP2008088146A (ja) | 2006-09-08 | 2008-04-17 | Kao Corp | インスリン感受性改善剤 |
| CN101562987B (zh) | 2006-12-22 | 2013-06-12 | 花王株式会社 | 容器装绿茶饮料 |
| WO2008081542A1 (ja) | 2006-12-28 | 2008-07-10 | Kao Corporation | 茶抽出物 |
| EP2127529B1 (de) * | 2007-01-24 | 2011-03-09 | Kao Corporation | Katechine enthaltende konditorwaren |
| JP2008200032A (ja) | 2007-01-24 | 2008-09-04 | Kao Corp | パン類 |
| US8367140B2 (en) | 2007-05-08 | 2013-02-05 | Kao Corporation | Concentrate composition for drink from concentrate |
| JP5517412B2 (ja) | 2007-05-24 | 2014-06-11 | 花王株式会社 | 精製緑茶抽出物 |
| US20120121761A1 (en) | 2007-08-08 | 2012-05-17 | Kao Corporation | Method for production of tea extract |
| EP2186418A4 (de) | 2007-08-30 | 2011-11-16 | Kao Corp | Instant-pulver-getränk |
| US8445031B2 (en) | 2007-09-05 | 2013-05-21 | Kao Corporation | Method for producing purified tea extract |
| JP2009268420A (ja) * | 2008-05-09 | 2009-11-19 | Kataoka & Co Ltd | 機能性食品組成物 |
| JP2010222277A (ja) * | 2009-03-23 | 2010-10-07 | Kao Corp | 食後の血糖値上昇抑制剤 |
| JP2011182703A (ja) * | 2010-03-08 | 2011-09-22 | Asahi Group Holdings Ltd | 1,2−ジ−O−ガロイル−4,6−HHDP−b−d−グルコピラノースを高濃度で含有する飲食品 |
| JP5744507B2 (ja) * | 2010-12-24 | 2015-07-08 | 三井農林株式会社 | α−アミラーゼ阻害剤 |
| CN106456693A (zh) * | 2014-04-23 | 2017-02-22 | 日本制纸株式会社 | 糖尿病预防或改善剂 |
| JP6355129B2 (ja) * | 2014-11-06 | 2018-07-11 | 国立研究開発法人農業・食品産業技術総合研究機構 | 1,2−ジ−O−ガロイル−4,6−HHDP−b−d−グルコピラノースを高濃度で含有する飲食品 |
| WO2018117002A1 (ja) | 2016-12-21 | 2018-06-28 | サントリーホールディングス株式会社 | エピガロカテキンガレート及びシクロプロリルトレオニンを含有する飲食品 |
| KR20220101432A (ko) | 2021-01-11 | 2022-07-19 | (주)아모레퍼시픽 | 갈로카테킨 갈레이트를 함유하는 녹차 추출물을 유효성분으로 포함하는 체지방 감소용 조성물 및 이의 제조방법 |
| JP7171954B2 (ja) | 2021-03-22 | 2022-11-15 | 花王株式会社 | カテキン類含有組成物 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS59219384A (ja) * | 1983-05-30 | 1984-12-10 | Mitsui Norin Kk | 天然抗酸化剤の製造方法 |
| JPS6013780A (ja) * | 1983-07-05 | 1985-01-24 | Mitsui Norin Kk | 茶カテキン類の製造方法 |
| JPS63214183A (ja) * | 1987-03-03 | 1988-09-06 | Mitsui Norin Kk | アンジオテンシン1変換酵素阻害剤 |
| JP2727471B2 (ja) * | 1989-09-14 | 1998-03-11 | 三井農林株式会社 | インフルエンザウィルス感染予防剤 |
-
1989
- 1989-10-19 JP JP1270228A patent/JP3018013B2/ja not_active Expired - Lifetime
-
1990
- 1990-04-12 AU AU53195/90A patent/AU628514B2/en not_active Ceased
- 1990-04-19 EP EP90107475A patent/EP0423419B1/de not_active Expired - Lifetime
- 1990-04-19 DE DE69012268T patent/DE69012268T2/de not_active Expired - Fee Related
- 1990-04-19 AT AT90107475T patent/ATE110963T1/de not_active IP Right Cessation
- 1990-04-19 CA CA002014971A patent/CA2014971C/en not_active Expired - Fee Related
- 1990-04-20 KR KR1019900005521A patent/KR0178522B1/ko not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP0423419A1 (de) | 1991-04-24 |
| AU628514B2 (en) | 1992-09-17 |
| EP0423419B1 (de) | 1994-09-07 |
| JP3018013B2 (ja) | 2000-03-13 |
| DE69012268T2 (de) | 1995-02-23 |
| JPH03133928A (ja) | 1991-06-07 |
| DE69012268D1 (de) | 1994-10-13 |
| KR0178522B1 (ko) | 1999-03-20 |
| CA2014971C (en) | 1999-12-14 |
| CA2014971A1 (en) | 1991-04-19 |
| KR910007538A (ko) | 1991-05-30 |
| AU5319590A (en) | 1991-04-26 |
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