ATE113830T1 - Ladung und gesteuerte abgabe von molekülen zu und von liposomen. - Google Patents

Ladung und gesteuerte abgabe von molekülen zu und von liposomen.

Info

Publication number
ATE113830T1
ATE113830T1 AT89309836T AT89309836T ATE113830T1 AT E113830 T1 ATE113830 T1 AT E113830T1 AT 89309836 T AT89309836 T AT 89309836T AT 89309836 T AT89309836 T AT 89309836T AT E113830 T1 ATE113830 T1 AT E113830T1
Authority
AT
Austria
Prior art keywords
liposomes
molecules
charge
controlled delivery
procedure
Prior art date
Application number
AT89309836T
Other languages
English (en)
Inventor
Yechezkel Barenholz
Gilad Haran
Original Assignee
Yissum Res Dev Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yissum Res Dev Co filed Critical Yissum Res Dev Co
Application granted granted Critical
Publication of ATE113830T1 publication Critical patent/ATE113830T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/22—Echographic preparations; Ultrasonic imaging preparations
    • A61K49/222—Echographic preparations; Ultrasonic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
    • A61K49/227—Liposomes, lipoprotein vesicles, e.g. LDL or HDL lipoproteins, micelles, e.g. phospholipidic or polymeric
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1277—Preparation processes; Proliposomes
    • A61K9/1278—Post-loading, e.g. by ion or pH gradient
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/829—Liposomes, e.g. encapsulation
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2984—Microcapsule with fluid core [includes liposome]

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Physics & Mathematics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Acoustics & Sound (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Preparation (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT89309836T 1988-09-28 1989-09-27 Ladung und gesteuerte abgabe von molekülen zu und von liposomen. ATE113830T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US25068788A 1988-09-28 1988-09-28

Publications (1)

Publication Number Publication Date
ATE113830T1 true ATE113830T1 (de) 1994-11-15

Family

ID=22948747

Family Applications (1)

Application Number Title Priority Date Filing Date
AT89309836T ATE113830T1 (de) 1988-09-28 1989-09-27 Ladung und gesteuerte abgabe von molekülen zu und von liposomen.

Country Status (11)

Country Link
US (2) US5192549A (de)
EP (1) EP0361894B1 (de)
JP (1) JP2659136B2 (de)
AT (1) ATE113830T1 (de)
CA (1) CA1335565C (de)
DE (2) DE68919321T2 (de)
ES (1) ES2067551T3 (de)
HK (1) HK26197A (de)
IL (1) IL91664A (de)
LU (1) LU88856I2 (de)
NL (1) NL960033I2 (de)

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IL91664A0 (en) 1990-04-29
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