ATE174793T1 - Verwendung von prolaktin-inhibitoren zur einstellung des zirkadianen prolaktin-rhythmus - Google Patents

Verwendung von prolaktin-inhibitoren zur einstellung des zirkadianen prolaktin-rhythmus

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Publication number
ATE174793T1
ATE174793T1 AT91300083T AT91300083T ATE174793T1 AT E174793 T1 ATE174793 T1 AT E174793T1 AT 91300083 T AT91300083 T AT 91300083T AT 91300083 T AT91300083 T AT 91300083T AT E174793 T1 ATE174793 T1 AT E174793T1
Authority
AT
Austria
Prior art keywords
prolactin
long term
treatment
peak
bromocriptine
Prior art date
Application number
AT91300083T
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English (en)
Inventor
Anthony Cincotta
Albert Meier
Original Assignee
Univ Louisiana State
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Publication date
Application filed by Univ Louisiana State filed Critical Univ Louisiana State
Application granted granted Critical
Publication of ATE174793T1 publication Critical patent/ATE174793T1/de

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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K31/13—Amines
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    • A61K31/13—Amines
    • A61K31/15—Oximes (>C=N—O—); Hydrazines (>N—N<); Hydrazones (>N—N=) ; Imines (C—N=C)
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    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/166—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the carbon of a carboxamide group directly attached to the aromatic ring, e.g. procainamide, procarbazine, metoclopramide, labetalol
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    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
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    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
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    • A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
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AT91300083T 1990-01-10 1991-01-07 Verwendung von prolaktin-inhibitoren zur einstellung des zirkadianen prolaktin-rhythmus ATE174793T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US46332790A 1990-01-10 1990-01-10

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ATE174793T1 true ATE174793T1 (de) 1999-01-15

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AT98110831T ATE391506T1 (de) 1990-01-10 1991-01-07 Verfahren zur langfristigen reduktion von körperfettspeichern, insulinresistenz, hyperinsulinämie und hyperglykämie in vertebraten
AT91300083T ATE174793T1 (de) 1990-01-10 1991-01-07 Verwendung von prolaktin-inhibitoren zur einstellung des zirkadianen prolaktin-rhythmus

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AT98110831T ATE391506T1 (de) 1990-01-10 1991-01-07 Verfahren zur langfristigen reduktion von körperfettspeichern, insulinresistenz, hyperinsulinämie und hyperglykämie in vertebraten

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US (2) US5496803A (de)
EP (2) EP0917874B1 (de)
JP (2) JP2896939B2 (de)
AT (2) ATE391506T1 (de)
CA (1) CA2030174C (de)
DE (2) DE69130651T2 (de)
DK (2) DK0917874T3 (de)
ES (2) ES2306465T3 (de)
GR (1) GR3029276T3 (de)

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US5744477A (en) * 1988-05-10 1998-04-28 The Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Method for treatment of obesity using prolactin modulators and diet
US5344832A (en) * 1990-01-10 1994-09-06 The Board Of Supervisors Of Louisiana University And Agricultural And Mechanical College Method for the long term reduction of body fat stores, insulin resistance, hyperinsulinemia and hyperglycemia in vertebrates
US5792748A (en) * 1995-06-07 1998-08-11 The General Hospital Corporation Method for inhibiting neoplastic disease in mammals
WO1996040132A1 (en) * 1995-06-07 1996-12-19 Ergo Science Incorporated Method for inhibiting neoplastic disease in mammals
ATE243513T1 (de) * 1996-05-01 2003-07-15 Gen Hospital Corp Wachstumshemmung und abtoetung solider tumore unter verwendung eines prolaktin-modulators und eines photosensitizers
US5866546A (en) * 1997-04-18 1999-02-02 Hadasit Medical Research Services And Development Company Ltd. Treatment for diabetes
AR019727A1 (es) 1998-06-30 2002-03-13 Takeda Chemical Industries Ltd Composicion farmaceutica
CA2387928A1 (en) * 1999-10-19 2001-04-26 Curagen Corporation Genes associated with obesity and methods for using the same
WO2001028539A2 (en) * 1999-10-19 2001-04-26 Glaxo Group Limited Agent for treating cephalic pain
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JPH1072372A (ja) 1998-03-17
CA2030174C (en) 1996-12-24
US5866584A (en) 1999-02-02
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EP0440333B1 (de) 1998-12-23
EP0917874B1 (de) 2008-04-09
DE69133595D1 (de) 2008-05-21
ATE391506T1 (de) 2008-04-15
ES2126563T3 (es) 1999-04-01
US5496803A (en) 1996-03-05
DE69133595T2 (de) 2009-06-10
CA2030174A1 (en) 1991-07-11
ES2306465T3 (es) 2008-11-01
EP0440333A2 (de) 1991-08-07
DK0440333T3 (da) 1999-08-23
DE69130651D1 (de) 1999-02-04
EP0440333A3 (en) 1992-06-17
GR3029276T3 (en) 1999-05-28
EP0917874A1 (de) 1999-05-26
JP2896939B2 (ja) 1999-05-31
DK0917874T3 (da) 2008-07-28

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